iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033899

Ensembl Protein ID

ENSECAP00000016646.1

UniProt Accession

F7B0Q7; F7B0Q7_HORSE

Protein Name

Uncharacterized protein

Gene Name

FXN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019174.1	ENSECAT00000020287.1	ENSECAP00000016646.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	90.85	2.00e-63	238.00	IUUC-Hsa-046921

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

SSSLHFLSQI LNVKKQSVCV MHLRTTGTLG DPGSLDETTY ERLAEETLDS LAEFFEDLAD 60
KPYTFEDYDV SFGSGVLTIK MGGDLGTYVI NKQTPNKQIW LSSPSSGPKR YDWTGKNWVY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTCGAGCC TCCACTTCCT CAGCCAGATT CTGAATGTCA AAAAGCAGAG TGTCTGTGTG 60
ATGCATTTGA GGACAACGGG GACTTTGGGT GACCCGGGGT AAGATAAAAC ACCTTCTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017789--Frataxin
IPR002908--Frataxin/CyaY
IPR020895--Frataxin_CS

PROSITE

PS01344--FRATAXIN_1
PS50810--FRATAXIN_2

Pfam

PF01491--Frataxin_Cyay

PRINTS

PR00904--FRATAXIN

SMART

SM01219--Frataxin_Cyay

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0051537--F:2 iron, 2 sulfur cluster binding
GO:0008199--F:ferric iron binding
GO:0008198--F:ferrous iron binding
GO:0004322--F:ferroxidase activity
GO:0034986--F:iron chaperone activity
GO:0007628--P:adult walking behavior
GO:0009060--P:aerobic respiration
GO:0006879--P:cellular iron ion homeostasis
GO:0070301--P:cellular response to hydrogen peroxide
GO:0034599--P:cellular response to oxidative stress
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0018283--P:iron incorporation into metallo-sulfur cluster
GO:0007005--P:mitochondrion organization
GO:0040015--P:negative regulation of multicellular organism growth
GO:0046621--P:negative regulation of organ growth
GO:0090201--P:negative regulation of release of cytochrome c from mitochondria
GO:0006119--P:oxidative phosphorylation
GO:1904234--P:positive regulation of aconitate hydratase activity
GO:0030307--P:positive regulation of cell growth
GO:0008284--P:positive regulation of cell proliferation
GO:1904231--P:positive regulation of succinate dehydrogenase activity
GO:0019230--P:proprioception
GO:0016540--P:protein autoprocessing
GO:0010722--P:regulation of ferrochelatase activity
GO:0010039--P:response to iron ion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002122	Ailuropoda melanoleuca	90.13	4.00e-79	286.00
IUUC-Apl-003853	Anas platyrhynchos	83.33	4.00e-57	212.00
IUUC-Aca-005026	Anolis carolinensis	72.11	3.00e-60	223.00
IUUC-Aly-006200	Arabidopsis lyrata	47.73	7.00e-19	86.70
IUUC-Ath-007033	Arabidopsis thaliana	47.73	6.00e-19	87.00
IUUC-Ago-007707	Ashbya gossypii	46.30	3.00e-19	86.70
IUUC-Acl-008146	Aspergillus clavatus	39.85	1.00e-18	85.90
IUUC-Afl-008501	Aspergillus flavus	38.18	1.00e-14	72.40
IUUC-Afu-008851	Aspergillus fumigatus	38.52	3.00e-18	84.70
IUUC-Ani-009129	Aspergillus nidulans	41.18	3.00e-12	64.70
IUUC-Ang-009557	Aspergillus niger	38.40	3.00e-17	81.60
IUUC-Ate-010486	Aspergillus terreus	39.20	5.00e-18	84.00
IUUC-Bgr-012108	Blumeria graminis	42.74	8.00e-16	76.60
IUUC-Bta-013437	Bos taurus	87.10	1.00e-68	252.00
IUUC-Bci-013810	Botrytis cinerea	53.25	1.00e-15	76.30
IUUC-Bdi-014226	Brachypodium distachyon	44.74	1.00e-23	102.00
IUUC-Bol-015092	Brassica oleracea	47.73	2.00e-19	88.20
IUUC-Bra-017945	Brassica rapa	46.67	6.00e-19	86.30
IUUC-Cel-018466	Caenorhabditis elegans	50.46	2.00e-25	107.00
IUUC-Cja-019306	Callithrix jacchus	90.20	1.00e-67	248.00
IUUC-Cfa-020063	Canis familiaris	88.24	4.00e-78	283.00
IUUC-Cpo-021325	Cavia porcellus	85.81	8.00e-76	275.00
IUUC-Cre-022889	Chlamydomonas reinhardtii	47.12	4.00e-21	94.40
IUUC-Csa-023739	Chlorocebus sabaeus	89.54	9.00e-78	282.00
IUUC-Cho-024324	Choloepus hoffmanni	89.03	6.00e-66	243.00
IUUC-Cgl-026402	Colletotrichum gloeosporioides	43.86	5.00e-19	87.40
IUUC-Cne-027094	Cryptococcus neoformans	38.82	4.00e-13	67.40
IUUC-Cme-027112	Cyanidioschyzon merolae	47.25	2.00e-13	68.20
IUUC-Dre-028813	Danio rerio	66.67	2.00e-44	171.00
IUUC-Dno-029949	Dasypus novemcinctus	86.76	4.00e-55	206.00
IUUC-Dse-031482	Dothistroma septosporum	41.03	1.00e-18	85.90
IUUC-Dme-031608	Drosophila melanogaster	51.22	3.00e-33	134.00
IUUC-Ete-032937	Echinops telfairi	96.88	2.00e-13	68.20
IUUC-Fca-036579	Felis catus	85.33	1.00e-64	239.00
IUUC-Fox-037940	Fusarium oxysporum	48.28	4.00e-23	100.00
IUUC-Fso-038465	Fusarium solani	50.86	1.00e-23	102.00
IUUC-Ggr-040089	Gaeumannomyces graminis	45.61	7.00e-21	93.60
IUUC-Gga-040910	Gallus gallus	78.72	5.00e-64	236.00
IUUC-Gma-044349	Glycine max	46.49	3.00e-24	104.00
IUUC-Ggo-044854	Gorilla gorilla	91.50	1.00e-65	242.00
IUUC-Hsa-046921	Homo sapiens	90.85	5.00e-65	240.00
IUUC-Hvu-047142	Hordeum vulgare	41.98	3.00e-24	104.00
IUUC-Kpa-049187	Komagataella pastoris	41.23	7.00e-16	76.30
IUUC-Lch-050614	Latimeria chalumnae	77.31	1.00e-54	205.00
IUUC-Lpe-051184	Leersia perrieri	38.93	3.00e-23	101.00
IUUC-Loc-052083	Lepisosteus oculatus	70.09	3.00e-47	179.00
IUUC-Lma-053209	Leptosphaeria maculans	40.18	4.00e-15	73.90
IUUC-Laf-054090	Loxodonta africana	87.58	8.00e-76	276.00
IUUC-Meu-056814	Macropus eugenii	77.33	8.00e-67	245.00
IUUC-Mor-057169	Magnaporthe oryzae	48.31	9.00e-23	99.80
IUUC-Mpo-057483	Magnaporthe poae	46.15	2.00e-22	98.60
IUUC-Mtr-058166	Medicago truncatula	47.62	2.00e-19	88.20
IUUC-Mla-059015	Melampsora laricipopulina	45.37	4.00e-19	87.00
IUUC-Mvi-060356	Microbotryum violaceum	51.06	1.00e-20	92.80
IUUC-Mdo-062658	Monodelphis domestica	79.33	9.00e-67	246.00
IUUC-Mmu-063470	Mus musculus	89.54	2.00e-77	281.00
IUUC-Mac-065327	Musa acuminata	48.28	9.00e-25	106.00
IUUC-Mpu-065761	Mustela putorius furo	86.36	1.00e-71	261.00
IUUC-Mlu-067175	Myotis lucifugus	90.85	8.00e-80	289.00
IUUC-Nfi-068535	Neosartorya fischeri	38.52	3.00e-18	84.70
IUUC-Ncr-068966	Neurospora crassa	43.20	9.00e-22	96.30
IUUC-Opr-070533	Ochotona princeps	54.84	2.00e-34	137.00
IUUC-Oan-073024	Ornithorhynchus anatinus	81.46	3.00e-60	224.00
IUUC-Ocu-074451	Oryctolagus cuniculus	86.27	2.00e-67	249.00
IUUC-Oba-075540	Oryza barthii	44.74	2.00e-23	102.00
IUUC-Obr-076285	Oryza brachyantha	37.67	3.00e-23	102.00
IUUC-Ogl-077827	Oryza glaberrima	44.74	2.00e-23	102.00
IUUC-Ogu-078491	Oryza glumaepatula	44.74	1.00e-23	102.00
IUUC-Oin-080149	Oryza indica	44.74	2.00e-23	102.00
IUUC-Olo-080318	Oryza longistaminata	42.50	9.00e-22	95.50
IUUC-Oni-083037	Oryza nivara	44.74	2.00e-23	102.00
IUUC-Opu-083448	Oryza punctata	44.74	1.00e-23	102.00
IUUC-Oru-084793	Oryza rufipogon	44.74	2.00e-23	102.00
IUUC-Osa-086032	Oryza sativa	44.74	2.00e-23	102.00
IUUC-Ola-086956	Oryzias latipes	63.28	5.00e-44	169.00
IUUC-Olu-087806	Ostreococcus lucimarinus	40.91	8.00e-17	79.70
IUUC-Oga-089029	Otolemur garnettii	90.91	7.00e-71	259.00
IUUC-Oar-089471	Ovis aries	85.16	3.00e-67	247.00
IUUC-Pan-092091	Papio anubis	90.20	7.00e-78	282.00
IUUC-Psi-093193	Pelodiscus sinensis	76.97	9.00e-68	248.00
IUUC-Pma-094540	Petromyzon marinus	60.50	7.00e-42	161.00
IUUC-Pno-094873	Phaeosphaeria nodorum	42.15	4.00e-17	81.30
IUUC-Ppa-095343	Physcomitrella patens	43.33	2.00e-17	82.80
IUUC-Pfo-097093	Poecilia formosa	55.80	4.00e-43	167.00
IUUC-Pab-098781	Pongo abelii	97.50	3.00e-29	120.00
IUUC-Pop-098983	Populus trichocarpa	39.13	7.00e-22	96.70
IUUC-Pca-100872	Procavia capensis	78.32	6.00e-55	206.00
IUUC-Ppe-101711	Prunus persica	50.00	1.00e-19	89.40
IUUC-Pva-102256	Pteropus vampyrus	93.38	3.00e-79	287.00
IUUC-Pgr-103607	Puccinia graminis	46.02	3.00e-21	94.70
IUUC-Pte-104220	Pyrenophora teres	37.29	1.00e-15	75.10
IUUC-Pyt-104562	Pyrenophora triticirepentis	37.29	6.00e-16	77.00
IUUC-Rno-105021	Rattus norvegicus	82.35	2.00e-72	264.00
IUUC-Sce-106182	Saccharomyces cerevisiae	49.30	1.00e-15	75.50
IUUC-Sha-107279	Sarcophilus harrisii	80.00	6.00e-68	249.00
IUUC-Sja-107819	Schizosaccharomyces japonicus	39.52	3.00e-19	87.40
IUUC-Spo-108197	Schizosaccharomyces pombe	38.93	2.00e-20	91.70
IUUC-Smo-108810	Selaginella moellendorffii	50.56	3.00e-21	93.20
IUUC-Sit-110256	Setaria italica	42.98	7.00e-23	100.00
IUUC-Sly-111448	Solanum lycopersicum	39.72	1.00e-22	99.40
IUUC-Stu-112702	Solanum tuberosum	44.74	1.00e-22	99.40
IUUC-Sbi-113956	Sorghum bicolor	46.09	1.00e-24	105.00
IUUC-Sre-115024	Sporisorium reilianum	37.98	1.00e-16	79.70
IUUC-Ssc-116034	Sus scrofa	90.32	1.00e-79	288.00
IUUC-Tgu-117503	Taeniopygia guttata	76.06	4.00e-56	209.00
IUUC-Tsy-119166	Tarsius syrichta	67.10	2.00e-45	174.00
IUUC-Tni-120703	Tetraodon nigroviridis	42.65	4.00e-24	103.00
IUUC-Tca-121473	Theobroma cacao	41.94	6.00e-20	90.10
IUUC-Tre-122241	Trichoderma reesei	44.83	8.00e-20	89.00
IUUC-Tvi-122347	Trichoderma virens	42.24	5.00e-18	84.00
IUUC-Tae-124560	Triticum aestivum	41.32	7.00e-23	100.00
IUUC-Tur-126452	Triticum urartu	44.74	4.00e-24	103.00
IUUC-Tme-127205	Tuber melanosporum	49.48	1.00e-19	87.40
IUUC-Ttr-128186	Tursiops truncatus	87.74	2.00e-74	271.00
IUUC-Uma-129523	Ustilago maydis	34.33	3.00e-15	74.70
IUUC-Vda-129793	Verticillium dahliae	45.61	2.00e-20	92.00
IUUC-Vpa-130040	Vicugna pacos	87.10	7.00e-76	275.00
IUUC-Vvi-131588	Vitis vinifera	40.32	8.00e-21	93.20
IUUC-Yli-134631	Yarrowia lipolytica	49.41	1.00e-17	82.40
IUUC-Zma-135478	Zea mays	46.49	4.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence