iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000073848.3	ENSDART00000163725.1	ENSDARP00000134316.1
ENSDARG00000073848.3	ENSDART00000108528.3	ENSDARP00000100870.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-15	57.7	166	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd+++v    ++++gW++g   l+gk G fP+n+v++++
   Q: 166  LVKARFNFQQTNEDELSFSKGDIIQVT--RQEEGGWWEG--ALNGKTGWFPSNYVKEIK 220
           68999*********************7..9999******..9**************986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MNSAEQTITW LITLGVLESP KKTLSDPEGF LQASLRDGVV LCKLLERLRP GSVHTIYQDP 60
RKDECLSNIR EFVKGCALYH IEVFEANDLL QGQNFSKVLN CLVALNKATS ESGGGSNSVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGCCCGA GCTCCAGATA TATTATCCTC CTCATCCTGA TTCCTGCGGC GGACACACGG 60
GAGATCTGTC ATTTCACACA CACAAACATT CAGCTTTGCT TATGGATTAA TCGCTTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0001525--P:angiogenesis
GO:0001568--P:blood vessel development
GO:0001935--P:endothelial cell proliferation
GO:0055113--P:epiboly involved in gastrulation with mouth forming second
GO:0035556--P:intracellular signal transduction
GO:0071896--P:protein localization to adherens junction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008379	Aspergillus clavatus	46.03	8.00e-12	66.60
IUUC-Afl-008545	Aspergillus flavus	47.46	9.00e-12	66.60
IUUC-Afu-009104	Aspergillus fumigatus	46.03	5.00e-12	67.40
IUUC-Ani-009428	Aspergillus nidulans	46.43	3.00e-11	65.10
IUUC-Aor-010139	Aspergillus oryzae	39.22	4.00e-12	67.80
IUUC-Ate-010289	Aspergillus terreus	46.30	4.00e-11	64.70
IUUC-Bgr-012305	Blumeria graminis	44.07	3.00e-12	67.80
IUUC-Bci-013864	Botrytis cinerea	47.37	5.00e-13	70.90
IUUC-Cgl-026676	Colletotrichum gloeosporioides	45.00	1.00e-12	69.30
IUUC-Cne-026866	Cryptococcus neoformans	52.54	2.00e-13	72.40
IUUC-Dse-031165	Dothistroma septosporum	50.00	5.00e-12	67.40
IUUC-Dme-032219	Drosophila melanogaster	43.81	2.00e-97	351.00
IUUC-Fox-037757	Fusarium oxysporum	41.67	7.00e-13	70.50
IUUC-Fso-038433	Fusarium solani	35.65	3.00e-13	71.20
IUUC-Ggr-040119	Gaeumannomyces graminis	44.26	2.00e-12	68.60
IUUC-Lma-053273	Leptosphaeria maculans	48.21	2.00e-12	68.60
IUUC-Mor-056932	Magnaporthe oryzae	44.26	2.00e-12	68.90
IUUC-Mpo-057322	Magnaporthe poae	42.03	1.00e-12	69.30
IUUC-Mtr-058576	Medicago truncatula	46.88	1.00e-10	60.80
IUUC-Nfi-068248	Neosartorya fischeri	46.03	5.00e-12	67.40
IUUC-Ncr-068791	Neurospora crassa	46.77	5.00e-13	70.50
IUUC-Pma-094701	Petromyzon marinus	58.07	6.00e-120	424.00
IUUC-Pte-104123	Pyrenophora teres	47.46	3.00e-12	68.20
IUUC-Pyt-104567	Pyrenophora triticirepentis	47.46	3.00e-12	68.20
IUUC-Ssl-108538	Sclerotinia sclerotiorum	45.61	3.00e-12	68.20
IUUC-Tre-121917	Trichoderma reesei	41.67	4.00e-13	70.90
IUUC-Tvi-122534	Trichoderma virens	41.67	5.00e-13	70.90
IUUC-Vpa-130144	Vicugna pacos	47.96	0.00e+00	678.00
IUUC-Xma-133901	Xiphophorus maculatus	67.83	0.00e+00	1081.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence