iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059410

Ensembl Protein ID

ENSMGAP00000015760.2

UniProt Accession

G1NPT5; G1NPT5_MELGA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014868.2	ENSMGAT00000016720.2	ENSMGAP00000015760.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-15	56.8	102	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 102  VVRAKFNFQQTNEDELSFSKGDIIHVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 156
           68999*********************7..999*******..8**************997 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

CESCFHEILD KCFHYLSFQT FDANDLYQGQ NFSKVLSSLV ALNKVTADIG LGSDSVCARP 60
SSHRIKSFDS LGSQSLHSRT SKLFQGQYRS LDMTDNSNHQ LVVRAKFNFQ QTNEDELSFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGAGAGCT GTTTTCATGA GATTTTGGAT AAGTGTTTTC ATTACCTCAG GCAAATATTA 60
TGAATTTTTT CTTTTTCTCC CCTTGAAAAT TCAGATGTTT AATGTCATCA CTGCTTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	92.76	0.00e+00	1162.00
IUUC-Aca-004591	Anolis carolinensis	93.73	0.00e+00	1300.00
IUUC-Afl-008545	Aspergillus flavus	48.08	7.00e-10	59.70
IUUC-Aor-010139	Aspergillus oryzae	48.08	6.00e-10	60.10
IUUC-Ame-010759	Astyanax mexicanus	75.22	0.00e+00	1164.00
IUUC-Bgr-012305	Blumeria graminis	41.43	2.00e-11	64.70
IUUC-Bta-013328	Bos taurus	90.73	0.00e+00	1350.00
IUUC-Cja-018742	Callithrix jacchus	93.34	0.00e+00	1176.00
IUUC-Cfa-020756	Canis familiaris	91.93	0.00e+00	1118.00
IUUC-Cpo-021284	Cavia porcellus	90.46	0.00e+00	1290.00
IUUC-Csa-023162	Chlorocebus sabaeus	92.72	0.00e+00	1360.00
IUUC-Cho-024736	Choloepus hoffmanni	74.58	1.00e-174	605.00
IUUC-Cin-025535	Ciona intestinalis	39.85	1.00e-93	336.00
IUUC-Cne-026866	Cryptococcus neoformans	50.79	2.00e-13	72.00
IUUC-Dre-028646	Danio rerio	75.34	0.00e+00	1158.00
IUUC-Dno-029461	Dasypus novemcinctus	93.98	0.00e+00	1367.00
IUUC-Dor-030623	Dipodomys ordii	82.10	0.00e+00	984.00
IUUC-Dse-031165	Dothistroma septosporum	50.00	2.00e-11	65.10
IUUC-Dme-032219	Drosophila melanogaster	45.59	4.00e-103	369.00
IUUC-Ete-032236	Echinops telfairi	79.84	0.00e+00	796.00
IUUC-Eca-034137	Equus caballus	94.22	0.00e+00	1338.00
IUUC-Fca-035742	Felis catus	89.95	0.00e+00	1082.00
IUUC-Fal-037205	Ficedula albicollis	98.16	0.00e+00	1244.00
IUUC-Fox-037757	Fusarium oxysporum	40.28	3.00e-12	67.40
IUUC-Fso-038433	Fusarium solani	40.28	3.00e-12	67.40
IUUC-Gmo-039475	Gadus morhua	67.92	0.00e+00	962.00
IUUC-Gga-040539	Gallus gallus	82.84	0.00e+00	1039.00
IUUC-Gac-042615	Gasterosteus aculeatus	64.24	0.00e+00	861.00
IUUC-Ggo-044470	Gorilla gorilla	88.59	0.00e+00	1277.00
IUUC-Hsa-046398	Homo sapiens	93.20	0.00e+00	1170.00
IUUC-Loc-052146	Lepisosteus oculatus	86.34	0.00e+00	1276.00
IUUC-Laf-053891	Loxodonta africana	93.13	0.00e+00	1389.00
IUUC-Mcc-055483	Macaca mulatta	92.91	0.00e+00	1169.00
IUUC-Mmr-060758	Microcebus murinus	91.93	0.00e+00	1127.00
IUUC-Mdo-061900	Monodelphis domestica	80.18	0.00e+00	1155.00
IUUC-Mmu-063849	Mus musculus	89.66	0.00e+00	1113.00
IUUC-Mpu-065876	Mustela putorius furo	91.41	0.00e+00	1103.00
IUUC-Mlu-067970	Myotis lucifugus	94.61	0.00e+00	1346.00
IUUC-Nle-069685	Nomascus leucogenys	74.75	0.00e+00	1009.00
IUUC-Opr-071132	Ochotona princeps	61.28	0.00e+00	677.00
IUUC-Ont-071815	Oreochromis niloticus	75.09	0.00e+00	1146.00
IUUC-Oan-073057	Ornithorhynchus anatinus	95.04	0.00e+00	1233.00
IUUC-Ola-086663	Oryzias latipes	73.59	0.00e+00	1066.00
IUUC-Oga-088103	Otolemur garnettii	92.97	0.00e+00	1288.00
IUUC-Ptr-091162	Pan troglodytes	92.81	0.00e+00	1176.00
IUUC-Pan-092093	Papio anubis	82.75	0.00e+00	1222.00
IUUC-Pma-094261	Petromyzon marinus	66.56	8.00e-127	446.00
IUUC-Pfo-096736	Poecilia formosa	67.29	0.00e+00	974.00
IUUC-Pab-097641	Pongo abelii	91.04	0.00e+00	1123.00
IUUC-Pva-102819	Pteropus vampyrus	88.67	0.00e+00	1106.00
IUUC-Pte-104123	Pyrenophora teres	47.06	1.00e-10	62.40
IUUC-Pyt-104567	Pyrenophora triticirepentis	47.06	1.00e-10	62.40
IUUC-Rno-106099	Rattus norvegicus	90.59	0.00e+00	1286.00
IUUC-Sha-106845	Sarcophilus harrisii	80.43	0.00e+00	1143.00
IUUC-Sly-111123	Solanum lycopersicum	44.23	2.00e-09	56.20
IUUC-Stu-112434	Solanum tuberosum	44.23	2.00e-09	56.20
IUUC-Ssc-116036	Sus scrofa	90.66	0.00e+00	1088.00
IUUC-Tgu-117498	Taeniopygia guttata	96.61	0.00e+00	1400.00
IUUC-Tru-118278	Takifugu rubripes	72.62	0.00e+00	1063.00
IUUC-Tsy-118990	Tarsius syrichta	90.02	0.00e+00	932.00
IUUC-Tni-120852	Tetraodon nigroviridis	73.19	0.00e+00	892.00
IUUC-Tre-121917	Trichoderma reesei	45.61	4.00e-12	67.00
IUUC-Tvi-122534	Trichoderma virens	45.61	4.00e-12	67.00
IUUC-Ttr-128922	Tursiops truncatus	88.36	0.00e+00	1065.00
IUUC-Xtr-132012	Xenopus tropicalis	85.34	0.00e+00	1141.00
IUUC-Xma-133901	Xiphophorus maculatus	63.97	0.00e+00	931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence