iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049969

Ensembl Protein ID

ENSLACP00000003502.1

UniProt Accession

H3A1I1; H3A1I1_LATCH

Genbank Protein ID

ENSLACP00000003502

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01128722

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003123.1	ENSLACT00000003533.1	ENSLACP00000003502.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-98	330.3	35	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 35   FGLVNFGNTCYCNSVLQALYFCQPFRENVLA-YKTQ------QKKKENLLTCLADLFHSINtqKKKVGVIPPKKFISRLRKENDLFDNY 116
           6******************************.3333......457889************966777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ + ++ e+++k ++++++d+Fqg+l+++++cl+c++vs+++e+fldls++v
   Q: 117  MQQDAHEFLNYLLNTVADIL---QEEKKQEKQNGKLKNGNANEGEENNKPEPTWVHDIFQGTLTNETRCLNCETVSNKDEDFLDLSVDV 202
           ********************...34555555555556666677888999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 203  EQNT-----SITHCLRDFSNTETLCSEHKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 284
           ****.....9**********************************************************************55555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts  ++++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 285  TSG-DAVNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 364
           774.45556****************************.888*******************999*****************97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MTVRNIASIC NMGTNASALE KDIGPEQFPI NEHYFGLVNF GNTCYCNSVL QALYFCQPFR 60
ENVLAYKTQQ KKKENLLTCL ADLFHSINTQ KKKVGVIPPK KFISRLRKEN DLFDNYMQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGGCTGG TAGAGCTGCT GCAGAGTGTA GGCTGCTTAC TCTCGTGTTT TGGGGACTTG 60
CGTCCTATTT GTTTTTTATA TATATATAGA TGTATCTAAA TCAGCCTCTC ACTGGACAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102347644

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.56	2.00e-124	438.00
IUUC-Aml-002353	Ailuropoda melanoleuca	95.05	0.00e+00	679.00
IUUC-Atr-002650	Amborella trichopoda	60.11	1.00e-124	439.00
IUUC-Apl-003380	Anas platyrhynchos	93.72	0.00e+00	677.00
IUUC-Aca-005031	Anolis carolinensis	95.90	0.00e+00	738.00
IUUC-Aly-005830	Arabidopsis lyrata	59.73	5.00e-124	437.00
IUUC-Ath-006663	Arabidopsis thaliana	59.07	4.00e-124	437.00
IUUC-Ame-010862	Astyanax mexicanus	95.12	0.00e+00	724.00
IUUC-Bta-013023	Bos taurus	95.29	0.00e+00	676.00
IUUC-Bdi-014008	Brachypodium distachyon	60.05	9.00e-124	436.00
IUUC-Bol-015138	Brassica oleracea	59.14	3.00e-124	437.00
IUUC-Bra-016956	Brassica rapa	59.62	2.00e-125	442.00
IUUC-Cel-018379	Caenorhabditis elegans	61.18	8.00e-142	496.00
IUUC-Cja-018956	Callithrix jacchus	94.28	0.00e+00	674.00
IUUC-Cfa-021064	Canis familiaris	96.05	0.00e+00	665.00
IUUC-Cpo-022443	Cavia porcellus	95.80	0.00e+00	674.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.93	5.00e-100	357.00
IUUC-Csa-023841	Chlorocebus sabaeus	96.72	0.00e+00	699.00
IUUC-Cin-025659	Ciona intestinalis	56.84	2.00e-130	458.00
IUUC-Dre-028230	Danio rerio	94.32	0.00e+00	723.00
IUUC-Dno-029209	Dasypus novemcinctus	94.25	0.00e+00	677.00
IUUC-Dme-032038	Drosophila melanogaster	80.79	3.00e-100	358.00
IUUC-Eca-033721	Equus caballus	96.61	0.00e+00	675.00
IUUC-Eeu-034916	Erinaceus europaeus	94.90	2.00e-155	541.00
IUUC-Fca-036299	Felis catus	94.26	0.00e+00	676.00
IUUC-Fox-037682	Fusarium oxysporum	42.63	1.00e-73	270.00
IUUC-Fso-038299	Fusarium solani	37.56	6.00e-74	271.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	695.00
IUUC-Ggr-039806	Gaeumannomyces graminis	43.48	3.00e-76	279.00
IUUC-Gga-041157	Gallus gallus	96.72	0.00e+00	701.00
IUUC-Gac-041764	Gasterosteus aculeatus	93.94	0.00e+00	707.00
IUUC-Gma-043828	Glycine max	60.60	3.00e-126	444.00
IUUC-Ggo-044659	Gorilla gorilla	94.55	0.00e+00	678.00
IUUC-Hsa-046156	Homo sapiens	96.72	0.00e+00	699.00
IUUC-Hvu-047692	Hordeum vulgare	58.58	1.00e-122	432.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	96.72	0.00e+00	699.00
IUUC-Kpa-049250	Komagataella pastoris	43.79	4.00e-68	252.00
IUUC-Lpe-051368	Leersia perrieri	59.56	3.00e-122	431.00
IUUC-Loc-052479	Lepisosteus oculatus	91.28	0.00e+00	694.00
IUUC-Laf-054085	Loxodonta africana	96.72	0.00e+00	699.00
IUUC-Mcc-055566	Macaca mulatta	94.79	0.00e+00	678.00
IUUC-Mor-057072	Magnaporthe oryzae	43.65	3.00e-75	276.00
IUUC-Mpo-057424	Magnaporthe poae	43.48	1.00e-76	280.00
IUUC-Mtr-057715	Medicago truncatula	60.93	2.00e-126	444.00
IUUC-Mga-059575	Meleagris gallopavo	96.61	0.00e+00	674.00
IUUC-Mvi-060357	Microbotryum violaceum	53.60	2.00e-77	283.00
IUUC-Mdo-062579	Monodelphis domestica	96.72	0.00e+00	698.00
IUUC-Mmu-063611	Mus musculus	96.72	0.00e+00	699.00
IUUC-Mac-065323	Musa acuminata	60.39	5.00e-122	430.00
IUUC-Mpu-066038	Mustela putorius furo	96.61	0.00e+00	673.00
IUUC-Mlu-068183	Myotis lucifugus	94.78	0.00e+00	681.00
IUUC-Nle-069330	Nomascus leucogenys	96.72	0.00e+00	699.00
IUUC-Opr-070980	Ochotona princeps	96.33	0.00e+00	672.00
IUUC-Ont-072134	Oreochromis niloticus	95.39	0.00e+00	733.00
IUUC-Oan-073583	Ornithorhynchus anatinus	91.55	0.00e+00	673.00
IUUC-Ocu-074923	Oryctolagus cuniculus	96.33	0.00e+00	671.00
IUUC-Oba-075220	Oryza barthii	59.73	1.00e-122	432.00
IUUC-Obr-076088	Oryza brachyantha	58.90	5.00e-120	423.00
IUUC-Ogl-077216	Oryza glaberrima	59.73	1.00e-122	432.00
IUUC-Ogu-078836	Oryza glumaepatula	59.73	1.00e-122	432.00
IUUC-Oin-079522	Oryza indica	59.73	1.00e-122	432.00
IUUC-Olo-080882	Oryza longistaminata	59.73	1.00e-122	432.00
IUUC-Ome-081549	Oryza meridionalis	59.73	1.00e-122	432.00
IUUC-Oni-082982	Oryza nivara	59.73	1.00e-122	432.00
IUUC-Opu-083532	Oryza punctata	59.73	6.00e-123	433.00
IUUC-Oru-084568	Oryza rufipogon	59.73	1.00e-122	432.00
IUUC-Osa-085299	Oryza sativa	59.73	1.00e-122	432.00
IUUC-Ola-086546	Oryzias latipes	93.66	0.00e+00	706.00
IUUC-Oga-088073	Otolemur garnettii	96.61	0.00e+00	675.00
IUUC-Oar-089248	Ovis aries	96.61	0.00e+00	674.00
IUUC-Ptr-090814	Pan troglodytes	96.72	0.00e+00	699.00
IUUC-Pan-091753	Papio anubis	96.72	0.00e+00	699.00
IUUC-Psi-094012	Pelodiscus sinensis	96.61	0.00e+00	672.00
IUUC-Ppa-095415	Physcomitrella patens	59.30	1.00e-126	446.00
IUUC-Pfo-097369	Poecilia formosa	95.93	0.00e+00	733.00
IUUC-Pab-098594	Pongo abelii	96.62	0.00e+00	677.00
IUUC-Pop-099798	Populus trichocarpa	59.84	7.00e-125	439.00
IUUC-Pca-100913	Procavia capensis	80.56	6.00e-153	533.00
IUUC-Ppe-101474	Prunus persica	59.84	1.00e-125	442.00
IUUC-Pva-102892	Pteropus vampyrus	96.61	0.00e+00	674.00
IUUC-Pgr-103306	Puccinia graminis	52.63	1.00e-94	341.00
IUUC-Rno-104909	Rattus norvegicus	96.45	0.00e+00	698.00
IUUC-Sha-107400	Sarcophilus harrisii	96.61	0.00e+00	673.00
IUUC-Smo-108829	Selaginella moellendorffii	59.66	1.00e-125	442.00
IUUC-Sit-110819	Setaria italica	59.51	1.00e-122	432.00
IUUC-Sly-111210	Solanum lycopersicum	60.55	3.00e-125	441.00
IUUC-Stu-112398	Solanum tuberosum	59.89	8.00e-126	442.00
IUUC-Sbi-114562	Sorghum bicolor	58.90	2.00e-122	431.00
IUUC-Ssc-115550	Sus scrofa	96.61	0.00e+00	674.00
IUUC-Tgu-116800	Taeniopygia guttata	96.72	0.00e+00	700.00
IUUC-Tru-118212	Takifugu rubripes	95.39	0.00e+00	733.00
IUUC-Tni-120071	Tetraodon nigroviridis	95.39	0.00e+00	734.00
IUUC-Tca-121329	Theobroma cacao	60.11	1.00e-125	442.00
IUUC-Tae-124807	Triticum aestivum	59.56	2.00e-125	442.00
IUUC-Tur-126563	Triticum urartu	59.56	2.00e-125	441.00
IUUC-Uma-129409	Ustilago maydis	47.08	2.00e-80	293.00
IUUC-Vpa-130590	Vicugna pacos	91.83	0.00e+00	628.00
IUUC-Vvi-131371	Vitis vinifera	60.11	8.00e-126	443.00
IUUC-Xma-133111	Xiphophorus maculatus	95.66	0.00e+00	731.00
IUUC-Yli-134632	Yarrowia lipolytica	45.21	2.00e-79	290.00
IUUC-Zma-134951	Zea mays	59.45	2.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence