iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fso-038158

Ensembl Protein ID

NechaP104852

UniProt Accession

C7ZA50; C7ZA50_NECH7

Genbank Protein ID

EEU39615.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

GG698912

Gene Name

NECHADRAFT_104852

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NechaG104852	NechaT104852	NechaP104852

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.40e-52	176.7	301	776
UBD/Alpha-Helix/UBA	8.30e-21	73.1	582	620

Active Site

Position(s)	Description	Evidence
310	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
731	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel...........w....kskkkavsprellkalkkeae 82
           tGlkNlgN+CY+ S+ QcL+ +p+++e +++  + +l+    ++p ++l ++l+kl   l           +     +++k  +p ++++ +++ +e
   Q: 301  TGLKNLGNSCYLASITQCLFDMPSFQERYFR-PNDDLPIV--QDPAEDLETQLRKLADGLlsgryskpdsdVggdgITHQKGLAPAMFKHLIGRGHE 394
           7******************************.88899887..789***************444444444331333455555**************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           efs+++qqDa E+l++l++ + ++                            ++ + +  ++ F++ l+++++cl c++v  +  +   + ++vp +
   Q: 395  EFSTMRQQDAFELLQHLFKLITRSQ---------------------------HQGGLKDPTEPFRFALEQRLQCLGCKKVRYSSTEQDNIFIDVPLE 464
           ********************99987...........................677888899*******************97777777788888888 PP
   S: 180  eetkke...........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspf 264
           +  ++e           +l++cL++ft++e++e    + c+ c +k   +k+  +k++P++L+++  ++  +  +++++k++  v +p+e + l+++
   Q: 465  KLPAEEgsdgpaaykpvTLKECLDNFTATEKVE----LTCSACGSKDGFVKRYLFKTFPDTLVVNARKM--TVVNWVPIKVDVPVIVPDEpFPLDSY 555
           877777889999********************9....9*******************************..6678********************** PP
   S: 265  cts.............................................................................................. 267
           +++                                                                                              
   Q: 556  LSQglqpgeeqlpdepeakapafepdatalaqleamgfprnrceralhatgnsdanaamewlfghmedpdidapldlggqsaggdtadpekiemlga 652
           ***9999999998888888888888888888888777777777777777777766666666666666666666666666666666666666666666 PP
   S: 268  .........peekqke...............................................kkkYeLiavvvHsG.slssGHYvayvkn..ekgk 305
                    +                                                     + +++L ++v+H+G s++ GHYva++++     +
   Q: 653  mgfgapqakK-----AlketggdveravewlfshpddqgtfdddapaegatsaskepagsatlPATFQLRSIVCHKGtSIHAGHYVAFIRKalG--D 742
           6666555550.....055555556666666666666666666666666777777778888888****************************551..3 PP
   S: 306  .....WllfdDskVtevkeeevleetgstaYvlfYkr 337
                W+lf+D+kV e   ++v+e++ + aYv+f+kr
   Q: 743  antptWVLFNDEKVVEA--HDVEEMR-KFAYVYFFKR 776
           44567*********988..5666644.79******98 PP

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +l+ql++MGF+r+++ +aL a+ n +++aA+e+L+ +
   Q: 582  ATALAQLEAMGFPRNRCERALHATgNSDANAAMEWLFGH 620
           578*********************************976 PP

Organism

Fusarium solani

Protein Sequence
(Fasta)

MACPHLESIG LNPPTPAQSV YREDCTQCFD SIDDPAGLDV CLQCFNGGCA GDRMHNRLHA 60
ALKSHPLTLN IRRTRKVVER DEPPAKMSKL AIAAETEEDR YDTALSVKCL ECNTELDRTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCTACTTC ACAGAGGATA ACTGAAAAAT TTCTTCTTTC CTCCTGTCAC TCCTCTACCC 60
CAAGCTGCAG AGAGAATAAC CAGAGAAGCC CGCCTATCAT GGCTTGCCCT CATCTCGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nhe:NECHADRAFT_104852

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.35	2.00e-95	342.00
IUUC-Aml-002104	Ailuropoda melanoleuca	35.57	8.00e-131	459.00
IUUC-Atr-002580	Amborella trichopoda	37.96	7.00e-65	240.00
IUUC-Apl-003774	Anas platyrhynchos	36.34	1.00e-128	452.00
IUUC-Aca-005368	Anolis carolinensis	35.77	3.00e-134	471.00
IUUC-Aly-005727	Arabidopsis lyrata	36.63	4.00e-122	430.00
IUUC-Ath-006974	Arabidopsis thaliana	36.76	3.00e-122	431.00
IUUC-Ago-007890	Ashbya gossypii	32.10	1.00e-111	395.00
IUUC-Acl-008057	Aspergillus clavatus	57.42	0.00e+00	909.00
IUUC-Afl-008547	Aspergillus flavus	58.58	0.00e+00	800.00
IUUC-Afu-008805	Aspergillus fumigatus	55.28	0.00e+00	808.00
IUUC-Ani-009441	Aspergillus nidulans	54.97	0.00e+00	745.00
IUUC-Ang-009720	Aspergillus niger	59.11	0.00e+00	928.00
IUUC-Aor-010111	Aspergillus oryzae	59.24	0.00e+00	959.00
IUUC-Ate-010531	Aspergillus terreus	55.36	0.00e+00	841.00
IUUC-Ame-011893	Astyanax mexicanus	36.01	1.00e-108	385.00
IUUC-Bgr-012183	Blumeria graminis	61.09	0.00e+00	985.00
IUUC-Bta-013179	Bos taurus	35.92	5.00e-130	456.00
IUUC-Bci-013858	Botrytis cinerea	67.18	0.00e+00	1123.00
IUUC-Bdi-014904	Brachypodium distachyon	34.16	3.00e-102	364.00
IUUC-Bol-015296	Brassica oleracea	35.77	1.00e-120	425.00
IUUC-Bra-017619	Brassica rapa	35.14	5.00e-120	423.00
IUUC-Cel-018625	Caenorhabditis elegans	31.30	3.00e-85	307.00
IUUC-Cja-019063	Callithrix jacchus	35.19	2.00e-126	445.00
IUUC-Cfa-020976	Canis familiaris	36.94	8.00e-134	469.00
IUUC-Cpo-022265	Cavia porcellus	36.42	6.00e-132	463.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	34.33	3.00e-68	251.00
IUUC-Csa-024177	Chlorocebus sabaeus	36.60	3.00e-121	427.00
IUUC-Cho-024702	Choloepus hoffmanni	34.78	5.00e-82	297.00
IUUC-Cin-025411	Ciona intestinalis	34.30	3.00e-105	374.00
IUUC-Csv-026347	Ciona savignyi	31.95	3.00e-100	357.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	77.51	0.00e+00	1164.00
IUUC-Cne-026831	Cryptococcus neoformans	48.67	0.00e+00	677.00
IUUC-Cme-027335	Cyanidioschyzon merolae	39.19	3.00e-50	192.00
IUUC-Dre-027982	Danio rerio	32.74	2.00e-109	388.00
IUUC-Dno-029034	Dasypus novemcinctus	36.15	3.00e-131	460.00
IUUC-Dor-030479	Dipodomys ordii	38.74	6.00e-62	230.00
IUUC-Dse-031467	Dothistroma septosporum	59.28	0.00e+00	927.00
IUUC-Dme-032075	Drosophila melanogaster	34.52	8.00e-112	396.00
IUUC-Ete-032865	Echinops telfairi	32.71	4.00e-109	387.00
IUUC-Eca-034059	Equus caballus	35.81	6.00e-129	453.00
IUUC-Eeu-035304	Erinaceus europaeus	36.50	3.00e-121	427.00
IUUC-Fca-035515	Felis catus	35.81	8.00e-130	456.00
IUUC-Fal-037271	Ficedula albicollis	37.31	2.00e-125	441.00
IUUC-Fox-037745	Fusarium oxysporum	88.93	0.00e+00	1397.00
IUUC-Gmo-039071	Gadus morhua	34.21	2.00e-115	408.00
IUUC-Ggr-040098	Gaeumannomyces graminis	71.28	0.00e+00	1091.00
IUUC-Gga-040635	Gallus gallus	35.48	2.00e-131	461.00
IUUC-Gac-042528	Gasterosteus aculeatus	35.01	8.00e-117	412.00
IUUC-Gma-043614	Glycine max	34.16	6.00e-110	390.00
IUUC-Ggo-044602	Gorilla gorilla	35.66	3.00e-129	454.00
IUUC-Hsa-045959	Homo sapiens	35.66	3.00e-129	454.00
IUUC-Hvu-047563	Hordeum vulgare	37.22	4.00e-100	357.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	35.97	3.00e-130	457.00
IUUC-Kpa-049156	Komagataella pastoris	42.71	6.00e-180	622.00
IUUC-Lch-049648	Latimeria chalumnae	35.13	2.00e-121	428.00
IUUC-Lpe-051523	Leersia perrieri	32.89	2.00e-101	361.00
IUUC-Loc-052072	Lepisosteus oculatus	31.51	2.00e-107	381.00
IUUC-Lma-053216	Leptosphaeria maculans	62.29	0.00e+00	984.00
IUUC-Laf-054327	Loxodonta africana	35.84	2.00e-130	457.00
IUUC-Mcc-055443	Macaca mulatta	35.69	1.00e-129	455.00
IUUC-Meu-056298	Macropus eugenii	35.58	1.00e-86	312.00
IUUC-Mor-057106	Magnaporthe oryzae	72.84	0.00e+00	1156.00
IUUC-Mpo-057589	Magnaporthe poae	71.16	0.00e+00	1093.00
IUUC-Mtr-058680	Medicago truncatula	36.44	9.00e-116	409.00
IUUC-Mla-058903	Melampsora laricipopulina	44.51	0.00e+00	641.00
IUUC-Mga-059669	Meleagris gallopavo	35.28	3.00e-125	441.00
IUUC-Mvi-060476	Microbotryum violaceum	45.84	0.00e+00	640.00
IUUC-Mmr-060575	Microcebus murinus	35.81	2.00e-129	454.00
IUUC-Mdo-062183	Monodelphis domestica	35.71	1.00e-130	458.00
IUUC-Mmu-063592	Mus musculus	35.81	2.00e-129	454.00
IUUC-Mac-065634	Musa acuminata	32.19	5.00e-104	370.00
IUUC-Mpu-066082	Mustela putorius furo	37.05	2.00e-133	468.00
IUUC-Mlu-067345	Myotis lucifugus	35.64	1.00e-130	458.00
IUUC-Nfi-068558	Neosartorya fischeri	57.67	0.00e+00	867.00
IUUC-Ncr-068960	Neurospora crassa	72.03	0.00e+00	1103.00
IUUC-Nle-070173	Nomascus leucogenys	36.56	9.00e-132	462.00
IUUC-Opr-070556	Ochotona princeps	35.81	6.00e-129	453.00
IUUC-Ont-071502	Oreochromis niloticus	34.95	5.00e-120	423.00
IUUC-Oan-072959	Ornithorhynchus anatinus	40.71	1.00e-44	171.00
IUUC-Ocu-074861	Oryctolagus cuniculus	37.40	3.00e-132	464.00
IUUC-Oba-075109	Oryza barthii	33.37	1.00e-106	378.00
IUUC-Obr-076292	Oryza brachyantha	33.29	2.00e-101	361.00
IUUC-Ogl-077065	Oryza glaberrima	34.43	2.00e-113	401.00
IUUC-Ogu-078776	Oryza glumaepatula	33.17	2.00e-109	388.00
IUUC-Oin-080048	Oryza indica	34.22	2.00e-111	395.00
IUUC-Olo-080711	Oryza longistaminata	33.08	2.00e-99	355.00
IUUC-Ome-081506	Oryza meridionalis	33.81	1.00e-100	359.00
IUUC-Oni-082320	Oryza nivara	33.02	4.00e-105	374.00
IUUC-Opu-083801	Oryza punctata	33.74	2.00e-100	358.00
IUUC-Oru-085139	Oryza rufipogon	32.82	1.00e-105	375.00
IUUC-Osa-085713	Oryza sativa	34.55	1.00e-114	405.00
IUUC-Ola-086951	Oryzias latipes	33.33	6.00e-110	390.00
IUUC-Olu-087822	Ostreococcus lucimarinus	33.45	3.00e-100	357.00
IUUC-Oga-088625	Otolemur garnettii	35.46	2.00e-129	454.00
IUUC-Oar-089995	Ovis aries	35.81	7.00e-131	459.00
IUUC-Ptr-090640	Pan troglodytes	36.58	2.00e-132	464.00
IUUC-Pan-091974	Papio anubis	35.53	3.00e-130	457.00
IUUC-Psi-093957	Pelodiscus sinensis	35.86	6.00e-135	473.00
IUUC-Pma-094242	Petromyzon marinus	40.89	3.00e-73	266.00
IUUC-Pno-094835	Phaeosphaeria nodorum	63.96	0.00e+00	907.00
IUUC-Ppa-095901	Physcomitrella patens	36.90	3.00e-125	440.00
IUUC-Pfo-097148	Poecilia formosa	34.82	5.00e-118	416.00
IUUC-Pab-098068	Pongo abelii	33.29	1.00e-109	389.00
IUUC-Pop-098943	Populus trichocarpa	35.94	7.00e-115	406.00
IUUC-Pca-100738	Procavia capensis	37.42	6.00e-98	350.00
IUUC-Ppe-101315	Prunus persica	34.97	6.00e-114	403.00
IUUC-Pva-102154	Pteropus vampyrus	35.81	2.00e-129	454.00
IUUC-Pgr-103343	Puccinia graminis	43.16	1.00e-152	531.00
IUUC-Ptt-103928	Puccinia triticina	38.45	2.00e-149	521.00
IUUC-Pte-104306	Pyrenophora teres	65.32	0.00e+00	966.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	64.67	0.00e+00	983.00
IUUC-Rno-105801	Rattus norvegicus	35.90	7.00e-130	456.00
IUUC-Sce-106304	Saccharomyces cerevisiae	34.64	3.00e-120	424.00
IUUC-Sha-107635	Sarcophilus harrisii	35.65	1.00e-131	462.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	43.46	2.00e-179	620.00
IUUC-Spo-108144	Schizosaccharomyces pombe	42.98	5.00e-179	619.00
IUUC-Smo-108703	Selaginella moellendorffii	37.04	1.00e-117	415.00
IUUC-Sit-110728	Setaria italica	33.91	2.00e-112	398.00
IUUC-Sly-111523	Solanum lycopersicum	37.33	7.00e-126	442.00
IUUC-Sar-113733	Sorex araneus	39.13	3.00e-55	208.00
IUUC-Sbi-114419	Sorghum bicolor	33.58	2.00e-107	381.00
IUUC-Sre-115225	Sporisorium reilianum	44.83	0.00e+00	639.00
IUUC-Ssc-115686	Sus scrofa	35.65	1.00e-129	455.00
IUUC-Tgu-117346	Taeniopygia guttata	35.32	3.00e-126	444.00
IUUC-Tru-118350	Takifugu rubripes	33.29	4.00e-116	410.00
IUUC-Tsy-119278	Tarsius syrichta	31.54	3.00e-90	324.00
IUUC-Tni-120658	Tetraodon nigroviridis	34.08	1.00e-111	395.00
IUUC-Tca-121585	Theobroma cacao	35.36	4.00e-114	404.00
IUUC-Tre-122043	Trichoderma reesei	81.62	0.00e+00	1260.00
IUUC-Tvi-122303	Trichoderma virens	80.26	0.00e+00	1254.00
IUUC-Tae-123798	Triticum aestivum	34.70	8.00e-111	392.00
IUUC-Tur-126732	Triticum urartu	31.84	5.00e-98	350.00
IUUC-Tme-126909	Tuber melanosporum	61.38	0.00e+00	935.00
IUUC-Tbe-127261	Tupaia belangeri	32.79	1.00e-78	286.00
IUUC-Ttr-128295	Tursiops truncatus	28.15	5.00e-84	303.00
IUUC-Uma-129599	Ustilago maydis	44.89	0.00e+00	677.00
IUUC-Vda-129688	Verticillium dahliae	78.54	0.00e+00	1203.00
IUUC-Vpa-130170	Vicugna pacos	40.08	4.00e-45	174.00
IUUC-Vvi-131116	Vitis vinifera	34.52	8.00e-109	386.00
IUUC-Xtr-131953	Xenopus tropicalis	34.27	5.00e-115	407.00
IUUC-Xma-133837	Xiphophorus maculatus	34.50	2.00e-118	418.00
IUUC-Yli-134510	Yarrowia lipolytica	45.47	4.00e-178	616.00
IUUC-Zma-135786	Zea mays	33.17	2.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence