iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095901

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

DS545372

Gene Name

PHYPADRAFT_155889

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S495_6V6	PP1S495_6V6.1	PP1S495_6V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-53	181.2	308	814
UBD/Alpha-Helix/UBA	1.90e-14	54.0	626	666

Active Site

Position(s)	Description	Evidence
318	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
757	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenpkepkgellkslqklfeel.............................wkskk 65
           tGl NlgN+CY+ Sv+Q+ ++++++++++ e  k   +  +++p +p+ +l ++l kl + +                             + + +
   Q: 308  TGLANLGNSCYLASVVQAVFSTKDFQRYYYEnvK-LDDAFKQAPADPTLDLHMQLSKLAHGIlsgkyavpskkgqdnevaeepkgknaltsMLQGQ 402
           7*****************************9744.444555678999***************6666666666666666555555555443335555 PP
   S: 66   kavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdn 161
             + pr++++ +++ ++ef +++qqDa Ef++++ldq+e++                                 +   + F++ ++++i+c   ++
   Q: 403  DGIPPRMFKSLIGTGHPEFASSRQQDALEFFQHFLDQVEQNH---------------------------VAAVGEDPARCFKFCVEERIMCSVSKK 471
           5**************************************998...........................3455566789***************** PP
   S: 162  vssreepfldlslpvpgkeetkke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPe 228
           v+ ++++ + lsl++p +   +k                               l+ cLe+f+++ee+ +   +y++  +++++a k+++l ++P+
   Q: 472  VKYTKKTDNILSLNIPLRAAVNKDevaayeknlaqkelageklsdeeivrprvPLSACLENFSAPEEVMD---FYSSAINARTTAIKTTRLATFPD 564
           ****************88876666889999**************************************97...*********************** PP
   S: 229  vLilhLkRfsfseeqksrekinkkvefpleLdlspfcts......................................................... 267
           +L+lh+ +f +  ++++++k++  +++p+e+d+s + ++                                                         
   Q: 565  YLVLHMRKF-VLAAGWVPKKLDVFIDVPDEIDISDMRSKgpqpdeqflpetpdgipeqvdsaadeaivsqladmgfprircekaaiqtlnsgleea 659
           *********.66889**********************99888777777777777777777777777777777777777766666666666666666 PP
   S: 268  ..........................peekqke............................................................... 274
                                     +     +                                                               
   Q: 660  mnwllvhmddpdiddpitrvgnnetsS-----Vtalnesdvetlvsfgflpemarkalkatggdmeraaewilnhpeesmameldvgactqdtqae 750
           666666666666666666666555550.....0555555555566666666666666666666666666667777777777777777777777788 PP
   S: 275  ......kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                 + kY+L+a v+H+G s++sGHYv++v++ +++W+ f+D kV ++   +  +   + +Y++f++r
   Q: 751  vkypdgSGKYRLLAFVSHMGtSTQSGHYVCHVRK-NDRWVIFNDCKVAVS--GDPPK---DMGYLYFFER 814
           899999****************************.888*********998..68888...8999999987 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +de ++ ql +MGF+r ++ +a  ++ n  le+A+++Ll +
   Q: 626  ADEAIVSQLADMGFPRIRCEKAAIQTlNSGLEEAMNWLLVH 666
           58999*********************************976 PP

Organism

Physcomitrella patens

Protein Sequence
(Fasta)

METLRSHLSR VRIPEPSYRI YKQECCVSFS TPRSEGGLFI DLYSFLAFGK DYVMWNYEKT 60
GNPVYLNIQE TPKQVSESRP HKKPTLLAIG VEGGFDSKVP EYEETYRIVI LPDFISLLYP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTACTAACT AGGGGTTTGT AAAACTGCAC GCATTCTCAC CCTCCCCGCA CAATCCCACG 60
CCCCTCTTGT CATCTCCACG CTCTCTTGCC AATCCGTCTT TCCCTTGTCG TTTCCCTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppp:PHYPADRAFT_155889

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	57.09	0.00e+00	882.00
IUUC-Aml-002104	Ailuropoda melanoleuca	48.21	0.00e+00	758.00
IUUC-Atr-002580	Amborella trichopoda	61.68	0.00e+00	1060.00
IUUC-Apl-003774	Anas platyrhynchos	49.34	0.00e+00	755.00
IUUC-Aca-005368	Anolis carolinensis	49.94	0.00e+00	801.00
IUUC-Aly-005727	Arabidopsis lyrata	64.76	0.00e+00	1046.00
IUUC-Ath-006974	Arabidopsis thaliana	64.39	0.00e+00	1045.00
IUUC-Ago-007890	Ashbya gossypii	28.05	8.00e-67	247.00
IUUC-Acl-008057	Aspergillus clavatus	35.19	1.00e-117	417.00
IUUC-Afl-008547	Aspergillus flavus	37.27	1.00e-111	396.00
IUUC-Afu-008805	Aspergillus fumigatus	36.01	9.00e-115	407.00
IUUC-Ani-009441	Aspergillus nidulans	35.01	2.00e-97	349.00
IUUC-Ang-009720	Aspergillus niger	35.60	2.00e-117	416.00
IUUC-Aor-010111	Aspergillus oryzae	35.30	1.00e-120	426.00
IUUC-Ate-010531	Aspergillus terreus	32.04	3.00e-96	345.00
IUUC-Ame-011470	Astyanax mexicanus	41.57	0.00e+00	654.00
IUUC-Bgr-012183	Blumeria graminis	32.42	1.00e-106	380.00
IUUC-Bta-013179	Bos taurus	48.32	0.00e+00	760.00
IUUC-Bci-013858	Botrytis cinerea	36.65	1.00e-129	456.00
IUUC-Bdi-014904	Brachypodium distachyon	60.83	0.00e+00	981.00
IUUC-Bol-015536	Brassica oleracea	64.56	0.00e+00	1057.00
IUUC-Bra-017939	Brassica rapa	64.22	0.00e+00	1056.00
IUUC-Cel-018625	Caenorhabditis elegans	32.38	1.00e-105	377.00
IUUC-Cja-019063	Callithrix jacchus	47.86	0.00e+00	752.00
IUUC-Cfa-020976	Canis familiaris	49.47	0.00e+00	776.00
IUUC-Cpo-022265	Cavia porcellus	49.41	0.00e+00	776.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	38.79	5.00e-110	390.00
IUUC-Csa-024177	Chlorocebus sabaeus	48.34	0.00e+00	682.00
IUUC-Cho-024522	Choloepus hoffmanni	34.77	5.00e-124	437.00
IUUC-Cin-025411	Ciona intestinalis	44.11	0.00e+00	649.00
IUUC-Csv-026347	Ciona savignyi	41.55	0.00e+00	630.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	34.94	4.00e-103	368.00
IUUC-Cne-026831	Cryptococcus neoformans	34.82	4.00e-113	401.00
IUUC-Cme-027335	Cyanidioschyzon merolae	27.90	4.00e-67	249.00
IUUC-Dre-027982	Danio rerio	46.24	0.00e+00	672.00
IUUC-Dno-029034	Dasypus novemcinctus	49.25	0.00e+00	766.00
IUUC-Dor-030130	Dipodomys ordii	35.20	3.00e-106	379.00
IUUC-Dse-031467	Dothistroma septosporum	35.84	4.00e-123	435.00
IUUC-Dme-032075	Drosophila melanogaster	45.11	0.00e+00	674.00
IUUC-Ete-032865	Echinops telfairi	45.15	0.00e+00	684.00
IUUC-Eca-034059	Equus caballus	48.56	0.00e+00	766.00
IUUC-Eeu-035304	Erinaceus europaeus	46.35	0.00e+00	694.00
IUUC-Fca-035515	Felis catus	48.55	0.00e+00	768.00
IUUC-Fal-037271	Ficedula albicollis	50.19	0.00e+00	749.00
IUUC-Fox-037745	Fusarium oxysporum	36.52	2.00e-121	429.00
IUUC-Fso-038158	Fusarium solani	35.98	6.00e-117	414.00
IUUC-Gmo-039071	Gadus morhua	45.62	0.00e+00	696.00
IUUC-Ggr-040098	Gaeumannomyces graminis	34.61	8.00e-113	400.00
IUUC-Gga-040635	Gallus gallus	48.68	0.00e+00	785.00
IUUC-Gac-042528	Gasterosteus aculeatus	46.28	0.00e+00	708.00
IUUC-Gma-043614	Glycine max	63.69	0.00e+00	1018.00
IUUC-Ggo-044602	Gorilla gorilla	48.55	0.00e+00	767.00
IUUC-Hsa-045959	Homo sapiens	48.55	0.00e+00	767.00
IUUC-Hvu-047563	Hordeum vulgare	60.24	0.00e+00	769.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	48.20	0.00e+00	762.00
IUUC-Kpa-049156	Komagataella pastoris	31.71	2.00e-99	355.00
IUUC-Lch-049648	Latimeria chalumnae	48.75	0.00e+00	762.00
IUUC-Lpe-051523	Leersia perrieri	59.98	0.00e+00	961.00
IUUC-Loc-052072	Lepisosteus oculatus	42.26	0.00e+00	660.00
IUUC-Lma-053216	Leptosphaeria maculans	35.78	3.00e-110	393.00
IUUC-Laf-054327	Loxodonta africana	48.32	0.00e+00	764.00
IUUC-Mcc-055443	Macaca mulatta	48.55	0.00e+00	766.00
IUUC-Meu-056298	Macropus eugenii	52.28	2.00e-166	578.00
IUUC-Mor-057106	Magnaporthe oryzae	34.69	5.00e-119	421.00
IUUC-Mpo-057589	Magnaporthe poae	34.89	4.00e-113	401.00
IUUC-Mtr-058680	Medicago truncatula	63.98	0.00e+00	1038.00
IUUC-Mla-058903	Melampsora laricipopulina	33.53	3.00e-107	382.00
IUUC-Mga-059669	Meleagris gallopavo	48.82	0.00e+00	748.00
IUUC-Mvi-060476	Microbotryum violaceum	33.65	3.00e-102	365.00
IUUC-Mmr-060575	Microcebus murinus	48.32	0.00e+00	761.00
IUUC-Mdo-062183	Monodelphis domestica	50.12	0.00e+00	786.00
IUUC-Mmu-063592	Mus musculus	48.55	0.00e+00	764.00
IUUC-Mac-065634	Musa acuminata	60.76	0.00e+00	1016.00
IUUC-Mpu-066082	Mustela putorius furo	49.23	0.00e+00	771.00
IUUC-Mlu-067345	Myotis lucifugus	48.27	0.00e+00	759.00
IUUC-Nfi-068558	Neosartorya fischeri	36.55	2.00e-122	432.00
IUUC-Ncr-068960	Neurospora crassa	33.50	2.00e-103	369.00
IUUC-Nle-070173	Nomascus leucogenys	49.58	0.00e+00	776.00
IUUC-Opr-070556	Ochotona princeps	48.78	0.00e+00	777.00
IUUC-Ont-071502	Oreochromis niloticus	46.93	0.00e+00	704.00
IUUC-Oan-072959	Ornithorhynchus anatinus	55.31	1.00e-71	261.00
IUUC-Ocu-074861	Oryctolagus cuniculus	49.58	0.00e+00	783.00
IUUC-Oba-075109	Oryza barthii	60.29	0.00e+00	967.00
IUUC-Obr-076292	Oryza brachyantha	60.98	0.00e+00	981.00
IUUC-Ogl-077065	Oryza glaberrima	61.39	0.00e+00	1001.00
IUUC-Ogu-078776	Oryza glumaepatula	60.29	0.00e+00	981.00
IUUC-Oin-080048	Oryza indica	61.39	0.00e+00	998.00
IUUC-Olo-080711	Oryza longistaminata	58.34	0.00e+00	885.00
IUUC-Ome-081506	Oryza meridionalis	59.62	0.00e+00	895.00
IUUC-Oni-082320	Oryza nivara	58.77	0.00e+00	958.00
IUUC-Opu-083801	Oryza punctata	61.22	0.00e+00	969.00
IUUC-Oru-085139	Oryza rufipogon	58.53	0.00e+00	956.00
IUUC-Osa-085713	Oryza sativa	61.51	0.00e+00	1004.00
IUUC-Ola-086951	Oryzias latipes	45.10	0.00e+00	691.00
IUUC-Olu-087822	Ostreococcus lucimarinus	39.43	2.00e-161	562.00
IUUC-Oga-088625	Otolemur garnettii	47.91	0.00e+00	757.00
IUUC-Oar-089995	Ovis aries	47.92	0.00e+00	756.00
IUUC-Ptr-090640	Pan troglodytes	47.86	0.00e+00	770.00
IUUC-Pan-091974	Papio anubis	48.21	0.00e+00	758.00
IUUC-Psi-093957	Pelodiscus sinensis	48.79	0.00e+00	799.00
IUUC-Pma-094242	Petromyzon marinus	49.12	2.00e-109	387.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.54	3.00e-105	375.00
IUUC-Pfo-097148	Poecilia formosa	46.81	0.00e+00	710.00
IUUC-Pab-098068	Pongo abelii	44.39	0.00e+00	641.00
IUUC-Pop-098943	Populus trichocarpa	64.60	0.00e+00	1030.00
IUUC-Pca-100738	Procavia capensis	46.59	8.00e-150	523.00
IUUC-Ppe-101315	Prunus persica	65.20	0.00e+00	1054.00
IUUC-Pva-102154	Pteropus vampyrus	48.20	0.00e+00	758.00
IUUC-Pgr-103343	Puccinia graminis	34.39	2.00e-98	352.00
IUUC-Ptt-103928	Puccinia triticina	29.43	3.00e-93	335.00
IUUC-Pte-104306	Pyrenophora teres	33.69	7.00e-102	364.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	34.91	2.00e-105	375.00
IUUC-Rno-105801	Rattus norvegicus	48.78	0.00e+00	767.00
IUUC-Sce-106304	Saccharomyces cerevisiae	29.55	2.00e-61	230.00
IUUC-Sha-107635	Sarcophilus harrisii	50.24	0.00e+00	780.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.85	2.00e-93	336.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.09	5.00e-116	411.00
IUUC-Smo-108848	Selaginella moellendorffii	66.46	0.00e+00	1041.00
IUUC-Sit-110728	Setaria italica	61.39	0.00e+00	1023.00
IUUC-Sly-111523	Solanum lycopersicum	64.30	0.00e+00	1071.00
IUUC-Sar-113733	Sorex araneus	44.26	3.00e-94	338.00
IUUC-Sbi-114419	Sorghum bicolor	61.29	0.00e+00	1015.00
IUUC-Sre-115225	Sporisorium reilianum	33.52	2.00e-116	412.00
IUUC-Ssc-115686	Sus scrofa	47.86	0.00e+00	757.00
IUUC-Tgu-117346	Taeniopygia guttata	48.97	0.00e+00	776.00
IUUC-Tru-118350	Takifugu rubripes	45.52	0.00e+00	691.00
IUUC-Tsy-119278	Tarsius syrichta	39.64	7.00e-166	577.00
IUUC-Tni-120658	Tetraodon nigroviridis	45.61	0.00e+00	671.00
IUUC-Tca-121585	Theobroma cacao	65.24	0.00e+00	1024.00
IUUC-Tre-122043	Trichoderma reesei	36.21	2.00e-123	435.00
IUUC-Tvi-122303	Trichoderma virens	35.46	3.00e-116	412.00
IUUC-Tae-123798	Triticum aestivum	60.71	0.00e+00	984.00
IUUC-Tur-126732	Triticum urartu	56.93	0.00e+00	919.00
IUUC-Tme-126909	Tuber melanosporum	35.91	6.00e-109	387.00
IUUC-Tbe-127261	Tupaia belangeri	43.10	4.00e-83	301.00
IUUC-Ttr-128295	Tursiops truncatus	39.58	3.00e-168	585.00
IUUC-Uma-129599	Ustilago maydis	34.72	2.00e-121	429.00
IUUC-Vda-129688	Verticillium dahliae	34.92	2.00e-112	399.00
IUUC-Vpa-130170	Vicugna pacos	44.66	3.00e-83	302.00
IUUC-Vvi-131116	Vitis vinifera	64.67	0.00e+00	1018.00
IUUC-Xtr-131953	Xenopus tropicalis	46.89	0.00e+00	741.00
IUUC-Xma-133837	Xiphophorus maculatus	46.69	0.00e+00	709.00
IUUC-Yli-134510	Yarrowia lipolytica	34.18	7.00e-106	377.00
IUUC-Zma-135786	Zea mays	61.05	0.00e+00	987.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence