iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sbi-114419

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM000762

Gene Name

SORBI_003G046300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Sb03g004040	Sb03g004040.1	Sb03g004040.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-54	186.6	310	792
UBD/Alpha-Helix/UBA	1.80e-15	57.3	669	708

Active Site

Position(s)	Description	Evidence
361	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
797	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw........kskkkavsprellkalkkeaeefsgy 87
           tGl NlgN+CYm S++Q++++++++ + ++e +  ++  +++p +p+ +l ++++kl + l+        k+ ++ + pr++++++++ ++efs++
   Q: 310  TGLANLGNSCYMASIMQVMFSTHPFISRYFEkQSLKAAFATAPADPTVDLNMQMTKLGHGLLsgkysapaKEGQEGIRPRMFKSVIAANHPEFSSM 405
           7************************99888834445555678899****************76666666688888********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeet 182
           +qqDa +f+ +l+d++e++                           + +++ ++    F++ ++++++c++ + ++ +r +  l+ls+p+++ ++ 
   Q: 406  RQQDALDFFLHLIDRVEKAN--------------------------PGNHELNPC-SGFKFIVEERVQCPSGKVSYnKRSDYILSLSIPLHEATN- 473
           ****************9988..........................444455554.57***********98776664555555666666665554. PP
   S: 183  kke.............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
            ke                              l+ cL+sf+ +ee+ +   +y++  ++k++a+k+ +++++P++L+lh+ +f + e++++++k+
   Q: 474  -KEqleafnekkaamdldgkevsnedivrprvPLEACLASFSGPEEIPD---FYSTALNSKTTATKTAGFNTFPDYLVLHMRKF-VMEAGWVPKKL 564
           .44569*****************************************97...********************************.77889****** PP
   S: 250  nkkvefpleLdlspfcts.............................................................................. 267
           + ++++p+++d++++ ++                                                                              
   Q: 565  DVYIDVPDTIDITHMRSKgvqpgeellpeggsgdnsaepahpvasedivsqlasmgfnylhcqkaaintsntgveeamnwllshmddpdindpisk 660
           *************99999999999999888888888888888888888888888888888777777777777777777777777777666666666 PP
   S: 268  ...........peekqke.............................................................kkkYeLiavvvHsG.sl 290
                            +                                                             + +Y+L+a v+H+G s+
   Q: 661  dsrasepsvdeA-----SvqtlisfgfqedvaikalkasggniekatdwifshpeasssasadsstsnanaddayipdgSGRYKLMAFVSHMGtST 751
           666655555550.....05555555555555555555555666666666666666666667777778888999999999***************** PP
   S: 291  ssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           ++GHYva+v + +g+W  f+DskV ++   +  +   + +Y++f++r
   Q: 752  HCGHYVAHVLK-DGRWTIFNDSKVAAS--VDLPK---EMGYLYFFQR 792
           ***********.9***********998..67788...8999999997 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
            de  ++ l++ GF ++ a++aL a+++n+e A+++++++
   Q: 669  VDEASVQTLISFGFQEDVAIKALKASGGNIEKATDWIFSH 708
           58899*********************************97 PP

Organism

Sorghum bicolor

Protein Sequence
(Fasta)

MDLLRSHLHK VRIPEPTNRI HKDECCVSFD TPRSEGGLYV DMSSFLGFGR EYVEWNFEKT 60
GNPVYLHIVQ RRKPEPDEAD RPLKKPTLLA IGVEGGFGDQ EPEYDDTFEI VILPDFVSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTTCCAA TCTTCCTCTC TCTTCGTCTC GCCGTCTCCA CCCCCCAAAA CCCTAGACGC 60
CACCCTCTAC CGCCGCCGCT CGCCGCCATC CGCGGCCATG GATCTCCTGC GTTCTCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sbi:SORBI_03g004040

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	81.00	0.00e+00	1267.00
IUUC-Aml-002104	Ailuropoda melanoleuca	47.43	0.00e+00	760.00
IUUC-Atr-002580	Amborella trichopoda	75.33	0.00e+00	628.00
IUUC-Apl-003774	Anas platyrhynchos	47.87	0.00e+00	740.00
IUUC-Aca-005368	Anolis carolinensis	48.31	0.00e+00	776.00
IUUC-Aly-005727	Arabidopsis lyrata	70.24	0.00e+00	1147.00
IUUC-Ath-006974	Arabidopsis thaliana	70.61	0.00e+00	1150.00
IUUC-Ago-007890	Ashbya gossypii	26.99	7.00e-70	258.00
IUUC-Acl-008057	Aspergillus clavatus	34.39	2.00e-116	412.00
IUUC-Afl-008547	Aspergillus flavus	35.17	3.00e-108	384.00
IUUC-Afu-008805	Aspergillus fumigatus	33.25	5.00e-103	367.00
IUUC-Ani-009441	Aspergillus nidulans	34.79	4.00e-96	344.00
IUUC-Ang-009720	Aspergillus niger	32.97	1.00e-107	383.00
IUUC-Aor-010111	Aspergillus oryzae	33.62	2.00e-117	415.00
IUUC-Ate-010531	Aspergillus terreus	32.31	9.00e-99	353.00
IUUC-Ame-011470	Astyanax mexicanus	42.01	0.00e+00	668.00
IUUC-Bgr-012183	Blumeria graminis	32.08	4.00e-103	368.00
IUUC-Bta-013179	Bos taurus	47.66	0.00e+00	765.00
IUUC-Bci-013858	Botrytis cinerea	32.19	4.00e-110	391.00
IUUC-Bdi-014904	Brachypodium distachyon	89.06	0.00e+00	1426.00
IUUC-Bol-015296	Brassica oleracea	70.90	0.00e+00	1150.00
IUUC-Bra-017939	Brassica rapa	71.64	0.00e+00	1157.00
IUUC-Cel-018625	Caenorhabditis elegans	33.00	2.00e-114	405.00
IUUC-Cja-019063	Callithrix jacchus	46.61	0.00e+00	755.00
IUUC-Cfa-020976	Canis familiaris	48.98	0.00e+00	776.00
IUUC-Cpo-022265	Cavia porcellus	48.98	0.00e+00	779.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	41.96	5.00e-119	420.00
IUUC-Csa-024177	Chlorocebus sabaeus	49.52	0.00e+00	684.00
IUUC-Cho-024522	Choloepus hoffmanni	35.87	1.00e-129	456.00
IUUC-Cin-025411	Ciona intestinalis	43.84	0.00e+00	635.00
IUUC-Csv-026347	Ciona savignyi	42.21	1.00e-178	619.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	32.39	9.00e-100	357.00
IUUC-Cne-026831	Cryptococcus neoformans	35.29	6.00e-116	410.00
IUUC-Cme-027335	Cyanidioschyzon merolae	29.95	8.00e-36	145.00
IUUC-Dre-027982	Danio rerio	44.69	0.00e+00	667.00
IUUC-Dno-029034	Dasypus novemcinctus	47.72	0.00e+00	765.00
IUUC-Dor-030130	Dipodomys ordii	42.37	4.00e-97	348.00
IUUC-Dse-031467	Dothistroma septosporum	34.15	2.00e-114	405.00
IUUC-Dme-032075	Drosophila melanogaster	45.75	0.00e+00	691.00
IUUC-Ete-032865	Echinops telfairi	44.39	0.00e+00	676.00
IUUC-Eca-034059	Equus caballus	47.67	0.00e+00	764.00
IUUC-Eeu-035304	Erinaceus europaeus	44.85	0.00e+00	676.00
IUUC-Fca-035515	Felis catus	47.78	0.00e+00	769.00
IUUC-Fal-037271	Ficedula albicollis	48.30	0.00e+00	720.00
IUUC-Fox-037745	Fusarium oxysporum	34.29	1.00e-115	410.00
IUUC-Fso-038158	Fusarium solani	32.88	2.00e-106	379.00
IUUC-Gmo-039071	Gadus morhua	45.22	0.00e+00	672.00
IUUC-Ggr-040098	Gaeumannomyces graminis	33.05	2.00e-107	382.00
IUUC-Gga-040635	Gallus gallus	47.42	0.00e+00	775.00
IUUC-Gac-042528	Gasterosteus aculeatus	44.17	0.00e+00	689.00
IUUC-Gma-043614	Glycine max	69.93	0.00e+00	1117.00
IUUC-Ggo-044602	Gorilla gorilla	47.66	0.00e+00	766.00
IUUC-Hsa-045959	Homo sapiens	47.66	0.00e+00	766.00
IUUC-Hvu-047563	Hordeum vulgare	83.70	0.00e+00	1080.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	47.31	0.00e+00	771.00
IUUC-Kpa-049156	Komagataella pastoris	32.25	2.00e-104	372.00
IUUC-Lch-049648	Latimeria chalumnae	47.90	0.00e+00	761.00
IUUC-Lpe-051523	Leersia perrieri	86.35	0.00e+00	1407.00
IUUC-Loc-052072	Lepisosteus oculatus	42.72	0.00e+00	664.00
IUUC-Lma-053216	Leptosphaeria maculans	34.11	3.00e-103	370.00
IUUC-Laf-054327	Loxodonta africana	47.42	0.00e+00	766.00
IUUC-Mcc-055443	Macaca mulatta	47.66	0.00e+00	764.00
IUUC-Meu-056298	Macropus eugenii	50.34	2.00e-157	548.00
IUUC-Mor-057106	Magnaporthe oryzae	33.70	4.00e-112	398.00
IUUC-Mpo-057589	Magnaporthe poae	33.33	8.00e-109	387.00
IUUC-Mtr-058680	Medicago truncatula	69.80	0.00e+00	1144.00
IUUC-Mla-058903	Melampsora laricipopulina	32.41	4.00e-105	375.00
IUUC-Mga-059669	Meleagris gallopavo	47.34	0.00e+00	728.00
IUUC-Mvi-060476	Microbotryum violaceum	32.46	3.00e-99	355.00
IUUC-Mmr-060575	Microcebus murinus	47.89	0.00e+00	766.00
IUUC-Mdo-062183	Monodelphis domestica	47.81	0.00e+00	762.00
IUUC-Mmu-063592	Mus musculus	48.00	0.00e+00	768.00
IUUC-Mac-065634	Musa acuminata	77.40	0.00e+00	687.00
IUUC-Mpu-066082	Mustela putorius furo	48.86	0.00e+00	769.00
IUUC-Mlu-067345	Myotis lucifugus	46.96	0.00e+00	757.00
IUUC-Nfi-068558	Neosartorya fischeri	34.64	4.00e-115	407.00
IUUC-Ncr-068960	Neurospora crassa	31.53	2.00e-101	362.00
IUUC-Nle-070173	Nomascus leucogenys	48.86	0.00e+00	773.00
IUUC-Opr-070556	Ochotona princeps	47.42	0.00e+00	775.00
IUUC-Ont-071502	Oreochromis niloticus	46.48	0.00e+00	692.00
IUUC-Oan-072959	Ornithorhynchus anatinus	49.79	6.00e-67	246.00
IUUC-Ocu-074861	Oryctolagus cuniculus	48.62	0.00e+00	781.00
IUUC-Oba-075109	Oryza barthii	87.03	0.00e+00	1408.00
IUUC-Obr-076292	Oryza brachyantha	88.55	0.00e+00	1394.00
IUUC-Ogl-077065	Oryza glaberrima	89.42	0.00e+00	1462.00
IUUC-Ogu-078776	Oryza glumaepatula	87.03	0.00e+00	1424.00
IUUC-Oin-080048	Oryza indica	89.04	0.00e+00	1454.00
IUUC-Olo-080711	Oryza longistaminata	84.94	0.00e+00	1313.00
IUUC-Ome-081506	Oryza meridionalis	86.85	0.00e+00	1324.00
IUUC-Oni-082320	Oryza nivara	84.70	0.00e+00	1399.00
IUUC-Opu-083801	Oryza punctata	87.78	0.00e+00	1385.00
IUUC-Oru-085139	Oryza rufipogon	84.58	0.00e+00	1396.00
IUUC-Osa-085713	Oryza sativa	89.42	0.00e+00	1465.00
IUUC-Ola-086951	Oryzias latipes	43.62	0.00e+00	667.00
IUUC-Olu-087822	Ostreococcus lucimarinus	41.53	7.00e-170	590.00
IUUC-Oga-088625	Otolemur garnettii	47.01	0.00e+00	761.00
IUUC-Oar-089995	Ovis aries	46.78	0.00e+00	758.00
IUUC-Ptr-090640	Pan troglodytes	46.84	0.00e+00	765.00
IUUC-Pan-091974	Papio anubis	46.85	0.00e+00	758.00
IUUC-Psi-093957	Pelodiscus sinensis	47.08	0.00e+00	780.00
IUUC-Pma-094242	Petromyzon marinus	47.55	8.00e-103	365.00
IUUC-Pno-094835	Phaeosphaeria nodorum	35.22	3.00e-95	342.00
IUUC-Ppa-095901	Physcomitrella patens	61.90	0.00e+00	1040.00
IUUC-Pfo-097148	Poecilia formosa	45.36	0.00e+00	685.00
IUUC-Pab-098068	Pongo abelii	43.39	0.00e+00	642.00
IUUC-Pop-098943	Populus trichocarpa	72.98	0.00e+00	1167.00
IUUC-Pca-100738	Procavia capensis	44.98	4.00e-146	511.00
IUUC-Ppe-101315	Prunus persica	71.02	0.00e+00	1150.00
IUUC-Pva-102154	Pteropus vampyrus	47.42	0.00e+00	761.00
IUUC-Pgr-103343	Puccinia graminis	32.56	2.00e-95	342.00
IUUC-Ptt-103928	Puccinia triticina	29.66	2.00e-89	322.00
IUUC-Pte-104306	Pyrenophora teres	32.57	4.00e-92	332.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	32.76	2.00e-95	342.00
IUUC-Rno-105801	Rattus norvegicus	48.24	0.00e+00	772.00
IUUC-Sce-106304	Saccharomyces cerevisiae	30.40	6.00e-69	254.00
IUUC-Sha-107635	Sarcophilus harrisii	49.04	0.00e+00	766.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	31.94	7.00e-94	337.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.74	2.00e-108	385.00
IUUC-Smo-108848	Selaginella moellendorffii	60.58	0.00e+00	943.00
IUUC-Sit-110728	Setaria italica	95.72	0.00e+00	1556.00
IUUC-Sly-111523	Solanum lycopersicum	68.78	0.00e+00	1163.00
IUUC-Sar-113733	Sorex araneus	45.97	7.00e-94	337.00
IUUC-Sre-115225	Sporisorium reilianum	33.18	2.00e-105	376.00
IUUC-Ssc-115686	Sus scrofa	46.72	0.00e+00	764.00
IUUC-Tgu-117346	Taeniopygia guttata	47.49	0.00e+00	757.00
IUUC-Tru-118350	Takifugu rubripes	43.40	0.00e+00	669.00
IUUC-Tsy-119278	Tarsius syrichta	39.66	2.00e-164	572.00
IUUC-Tni-120658	Tetraodon nigroviridis	43.94	0.00e+00	660.00
IUUC-Tca-121585	Theobroma cacao	71.73	0.00e+00	1152.00
IUUC-Tre-122043	Trichoderma reesei	33.99	6.00e-109	387.00
IUUC-Tvi-122303	Trichoderma virens	33.41	1.00e-109	389.00
IUUC-Tae-123798	Triticum aestivum	86.29	0.00e+00	1414.00
IUUC-Tur-126732	Triticum urartu	80.88	0.00e+00	1318.00
IUUC-Tme-126909	Tuber melanosporum	34.30	2.00e-103	369.00
IUUC-Tbe-127261	Tupaia belangeri	40.43	2.00e-121	429.00
IUUC-Ttr-129119	Tursiops truncatus	53.66	6.00e-111	394.00
IUUC-Uma-129599	Ustilago maydis	33.53	4.00e-114	405.00
IUUC-Vda-129688	Verticillium dahliae	33.37	1.00e-104	373.00
IUUC-Vpa-130170	Vicugna pacos	36.75	2.00e-144	505.00
IUUC-Vvi-131116	Vitis vinifera	72.75	0.00e+00	1155.00
IUUC-Xtr-131953	Xenopus tropicalis	45.30	0.00e+00	716.00
IUUC-Xma-133837	Xiphophorus maculatus	45.24	0.00e+00	682.00
IUUC-Yli-134510	Yarrowia lipolytica	34.33	2.00e-107	382.00
IUUC-Zma-135786	Zea mays	95.72	0.00e+00	1496.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence