iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049290

Ensembl Protein ID

CAY70761

UniProt Accession

C4R5C5; C4R5C5_KOMPG

Genbank Protein ID

CAY70761.1

Protein Name

Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal protein

Genbank Nucleotide ID

FN392321

Gene Name

PAS_chr3_0710

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr3_0710	CAY70761	CAY70761

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.30e-55	183.1	5	139
UBD/UBC-like/UBD_UBC	1.00e-75	250.5	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesv 101
           R++kel +l +dpp+++sa+pv + dl++w++ i+Gp+d+pY+ggvF l+i+fp+dYPfkPPk++f+tki+hPn++++G++Cl+ilk  ++Wspal++++v
   Q: 5    RINKELIDLGRDPPTSCSAGPVGD-DLYHWQASIMGPPDSPYAGGVFFLSIHFPTDYPFKPPKIQFTTKIYHPNINASGNICLDILK--DQWSPALTISKV 102
           89**********************.9************************************************************9..************ PP
   S: 102  llsiqsllaepnpesplneeaaellkknreeykkkvr 138
           llsi+sll+++np++pl  e+a+++k++r++y+ +++
   Q: 103  LLSICSLLTDANPDDPLVPEIAHIYKSDRAKYEATAK 139
           *********************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskvlls 101
           ri+kel dl rd+++ +sa++v+ddl++++a i+gppdspy ggvffl i++ptdypfkppk++f+tkiyhpnin++g icldil++qws+alt+skvlls
   Q: 5    RINKELIDLGRDPPTSCSAGPVGDDLYHWQASIMGPPDSPYAGGVFFLSIHFPTDYPFKPPKIQFTTKIYHPNINASGNICLDILKDQWSPALTISKVLLS 105
           8**************************************************************************************************** PP
   S: 102  lcslladaepddplvaeiariyktdkekykriarewt 138
           +csll+da+pddplv+eia+iyk+d+ ky+ +a+ewt
   Q: 106  ICSLLTDANPDDPLVPEIAHIYKSDRAKYEATAKEWT 142
           ************************************8 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSSKRINKEL IDLGRDPPTS CSAGPVGDDL YHWQASIMGP PDSPYAGGVF FLSIHFPTDY 60
PFKPPKIQFT TKIYHPNINA SGNICLDILK DQWSPALTIS KVLLSICSLL TDANPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTCCA AAAGAATCAA CAAAGAACTG ATCGATTTGG GAAGAGATCC CCCCACGTCG 60
TGCTCAGCTG GCCCTGTTGG AGACGATCTC TACCATTGGC AAGCTTCTAT AATGGGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0000502--C:proteasome complex
GO:0005524--F:ATP binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034605--P:cellular response to heat
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

ppa:PAS_chr3_0710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	78.23	1.00e-70	256.00
IUUC-Aml-001563	Ailuropoda melanoleuca	78.23	8.00e-69	249.00
IUUC-Atr-002894	Amborella trichopoda	78.91	8.00e-71	256.00
IUUC-Apl-004043	Anas platyrhynchos	78.17	3.00e-67	244.00
IUUC-Aca-005236	Anolis carolinensis	78.23	2.00e-69	251.00
IUUC-Aly-006221	Arabidopsis lyrata	78.23	7.00e-71	256.00
IUUC-Ath-007700	Arabidopsis thaliana	78.23	1.00e-70	255.00
IUUC-Ago-007967	Ashbya gossypii	95.92	2.00e-81	291.00
IUUC-Acl-008266	Aspergillus clavatus	82.31	3.00e-75	271.00
IUUC-Afl-008709	Aspergillus flavus	76.76	5.00e-70	256.00
IUUC-Afu-008956	Aspergillus fumigatus	82.99	2.00e-75	271.00
IUUC-Ani-009401	Aspergillus nidulans	80.95	4.00e-74	267.00
IUUC-Ang-009725	Aspergillus niger	83.20	7.00e-64	233.00
IUUC-Aor-010157	Aspergillus oryzae	82.31	4.00e-75	271.00
IUUC-Ate-010438	Aspergillus terreus	82.99	5.00e-75	270.00
IUUC-Ame-011566	Astyanax mexicanus	78.91	7.00e-70	253.00
IUUC-Bgr-012238	Blumeria graminis	78.23	2.00e-70	255.00
IUUC-Bta-013158	Bos taurus	78.23	2.00e-69	251.00
IUUC-Bci-013661	Botrytis cinerea	81.63	2.00e-75	271.00
IUUC-Bdi-014832	Brachypodium distachyon	78.23	1.00e-70	255.00
IUUC-Bol-016512	Brassica oleracea	79.59	9.00e-72	259.00
IUUC-Bra-017985	Brassica rapa	79.59	9.00e-72	259.00
IUUC-Cel-018362	Caenorhabditis elegans	78.91	8.00e-71	256.00
IUUC-Cja-019886	Callithrix jacchus	78.23	2.00e-69	251.00
IUUC-Cfa-020436	Canis familiaris	78.23	2.00e-69	251.00
IUUC-Cpo-021714	Cavia porcellus	78.23	5.00e-69	250.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	80.27	1.00e-71	259.00
IUUC-Csa-023668	Chlorocebus sabaeus	78.23	8.00e-69	249.00
IUUC-Cho-024987	Choloepus hoffmanni	78.23	8.00e-69	249.00
IUUC-Cin-025379	Ciona intestinalis	75.51	3.00e-68	248.00
IUUC-Csv-026311	Ciona savignyi	72.79	1.00e-64	235.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	82.99	9.00e-76	273.00
IUUC-Cne-026957	Cryptococcus neoformans	82.31	5.00e-74	267.00
IUUC-Cme-027220	Cyanidioschyzon merolae	80.27	6.00e-73	263.00
IUUC-Dre-028804	Danio rerio	78.91	9.00e-70	253.00
IUUC-Dno-030067	Dasypus novemcinctus	78.23	8.00e-69	249.00
IUUC-Dor-030323	Dipodomys ordii	78.23	1.00e-69	253.00
IUUC-Dse-031397	Dothistroma septosporum	82.31	1.00e-75	272.00
IUUC-Dme-031594	Drosophila melanogaster	80.95	5.00e-72	260.00
IUUC-Ete-032540	Echinops telfairi	78.23	8.00e-69	249.00
IUUC-Eca-034167	Equus caballus	78.23	8.00e-69	249.00
IUUC-Eeu-034766	Erinaceus europaeus	78.57	7.00e-65	236.00
IUUC-Fca-035917	Felis catus	78.23	1.00e-69	252.00
IUUC-Fal-036904	Ficedula albicollis	78.57	2.00e-66	242.00
IUUC-Fox-038021	Fusarium oxysporum	82.31	3.00e-75	271.00
IUUC-Fso-038297	Fusarium solani	81.63	7.00e-75	270.00
IUUC-Gmo-038775	Gadus morhua	78.91	2.00e-69	252.00
IUUC-Ggr-039912	Gaeumannomyces graminis	78.29	2.00e-70	255.00
IUUC-Gga-041015	Gallus gallus	78.91	7.00e-70	253.00
IUUC-Gac-041509	Gasterosteus aculeatus	78.23	1.00e-69	252.00
IUUC-Gma-044383	Glycine max	79.59	3.00e-71	258.00
IUUC-Ggo-045361	Gorilla gorilla	78.91	4.00e-70	254.00
IUUC-Hsa-045934	Homo sapiens	78.91	4.00e-70	254.00
IUUC-Hvu-047546	Hordeum vulgare	76.19	3.00e-69	251.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	78.23	8.00e-69	249.00
IUUC-Lch-050109	Latimeria chalumnae	75.51	1.00e-67	245.00
IUUC-Lpe-051194	Leersia perrieri	78.23	1.00e-70	257.00
IUUC-Loc-052838	Lepisosteus oculatus	78.91	4.00e-70	254.00
IUUC-Lma-053121	Leptosphaeria maculans	81.63	2.00e-75	271.00
IUUC-Laf-054244	Loxodonta africana	76.19	4.00e-60	221.00
IUUC-Mcc-055421	Macaca mulatta	78.91	4.00e-70	254.00
IUUC-Meu-056462	Macropus eugenii	78.42	1.00e-65	239.00
IUUC-Mor-057235	Magnaporthe oryzae	82.31	3.00e-75	271.00
IUUC-Mpo-057596	Magnaporthe poae	78.29	2.00e-70	255.00
IUUC-Mtr-058532	Medicago truncatula	78.91	2.00e-70	255.00
IUUC-Mla-059189	Melampsora laricipopulina	79.59	3.00e-70	254.00
IUUC-Mga-059237	Meleagris gallopavo	78.57	2.00e-66	241.00
IUUC-Mvi-060397	Microbotryum violaceum	80.95	2.00e-72	261.00
IUUC-Mmr-060889	Microcebus murinus	78.91	7.00e-70	253.00
IUUC-Mdo-062962	Monodelphis domestica	78.23	2.00e-69	251.00
IUUC-Mmu-063796	Mus musculus	78.91	7.00e-70	253.00
IUUC-Mac-065211	Musa acuminata	79.59	1.00e-71	259.00
IUUC-Mpu-065724	Mustela putorius furo	78.23	8.00e-69	249.00
IUUC-Mlu-067573	Myotis lucifugus	78.57	6.00e-66	240.00
IUUC-Nfi-068599	Neosartorya fischeri	82.99	2.00e-75	271.00
IUUC-Ncr-068677	Neurospora crassa	81.63	2.00e-74	268.00
IUUC-Nle-069715	Nomascus leucogenys	78.91	4.00e-70	254.00
IUUC-Opr-070191	Ochotona princeps	78.42	5.00e-66	240.00
IUUC-Ont-071403	Oreochromis niloticus	78.23	6.00e-69	250.00
IUUC-Oan-073026	Ornithorhynchus anatinus	78.72	3.00e-67	245.00
IUUC-Ocu-074315	Oryctolagus cuniculus	78.23	2.00e-69	251.00
IUUC-Oba-075411	Oryza barthii	78.91	1.00e-70	256.00
IUUC-Obr-076481	Oryza brachyantha	78.23	3.00e-70	254.00
IUUC-Ogl-077772	Oryza glaberrima	78.91	1.00e-70	256.00
IUUC-Ogu-078981	Oryza glumaepatula	78.91	1.00e-70	256.00
IUUC-Oin-079652	Oryza indica	78.91	1.00e-70	256.00
IUUC-Olo-080786	Oryza longistaminata	78.91	1.00e-70	256.00
IUUC-Ome-081987	Oryza meridionalis	78.23	2.00e-70	255.00
IUUC-Oni-082391	Oryza nivara	78.23	1.00e-70	257.00
IUUC-Opu-084027	Oryza punctata	78.23	2.00e-70	255.00
IUUC-Oru-085167	Oryza rufipogon	78.23	2.00e-70	257.00
IUUC-Osa-085982	Oryza sativa	78.23	2.00e-70	255.00
IUUC-Ola-087515	Oryzias latipes	78.23	3.00e-69	251.00
IUUC-Olu-087615	Ostreococcus lucimarinus	75.00	7.00e-66	240.00
IUUC-Oga-088915	Otolemur garnettii	78.23	8.00e-69	249.00
IUUC-Oar-090038	Ovis aries	78.23	1.00e-69	252.00
IUUC-Ptr-090707	Pan troglodytes	78.23	2.00e-69	251.00
IUUC-Pan-092143	Papio anubis	78.23	2.00e-69	251.00
IUUC-Psi-094076	Pelodiscus sinensis	78.23	1.00e-69	252.00
IUUC-Pma-094405	Petromyzon marinus	77.54	8.00e-64	233.00
IUUC-Pno-094765	Phaeosphaeria nodorum	81.63	2.00e-75	271.00
IUUC-Ppa-095177	Physcomitrella patens	78.91	7.00e-71	256.00
IUUC-Pfo-096867	Poecilia formosa	78.23	3.00e-69	251.00
IUUC-Pab-098760	Pongo abelii	78.91	2.00e-70	255.00
IUUC-Pop-098986	Populus trichocarpa	79.59	7.00e-71	256.00
IUUC-Pca-100678	Procavia capensis	78.23	8.00e-69	249.00
IUUC-Ppe-101387	Prunus persica	78.91	5.00e-71	257.00
IUUC-Pva-102770	Pteropus vampyrus	78.23	8.00e-69	249.00
IUUC-Pgr-103381	Puccinia graminis	79.59	2.00e-69	252.00
IUUC-Ptt-103723	Puccinia triticina	77.86	3.00e-62	228.00
IUUC-Pte-104015	Pyrenophora teres	81.63	3.00e-75	271.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	81.63	3.00e-75	271.00
IUUC-Rno-105498	Rattus norvegicus	78.23	1.00e-69	252.00
IUUC-Sce-106153	Saccharomyces cerevisiae	92.47	8.00e-79	283.00
IUUC-Sha-106489	Sarcophilus harrisii	77.46	2.00e-66	242.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	82.99	9.00e-76	273.00
IUUC-Spo-108032	Schizosaccharomyces pombe	82.31	4.00e-75	270.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	82.31	9.00e-76	273.00
IUUC-Smo-109317	Selaginella moellendorffii	79.59	2.00e-71	258.00
IUUC-Sit-109936	Setaria italica	78.23	1.00e-70	256.00
IUUC-Sly-111055	Solanum lycopersicum	79.59	1.00e-71	259.00
IUUC-Stu-112192	Solanum tuberosum	78.91	7.00e-71	256.00
IUUC-Sar-113302	Sorex araneus	79.14	2.00e-66	241.00
IUUC-Sbi-113792	Sorghum bicolor	78.91	1.00e-70	256.00
IUUC-Sre-115037	Sporisorium reilianum	79.17	2.00e-70	255.00
IUUC-Ssc-115391	Sus scrofa	78.91	4.00e-70	254.00
IUUC-Tgu-116727	Taeniopygia guttata	78.23	1.00e-69	252.00
IUUC-Tru-118628	Takifugu rubripes	78.91	1.00e-69	252.00
IUUC-Tsy-118832	Tarsius syrichta	78.23	4.00e-68	247.00
IUUC-Tni-120056	Tetraodon nigroviridis	77.55	1.00e-68	249.00
IUUC-Tca-121375	Theobroma cacao	80.27	3.00e-71	257.00
IUUC-Tre-122125	Trichoderma reesei	80.95	6.00e-73	263.00
IUUC-Tvi-122296	Trichoderma virens	80.95	6.00e-73	263.00
IUUC-Tae-125784	Triticum aestivum	78.23	2.00e-70	255.00
IUUC-Tur-126518	Triticum urartu	78.23	2.00e-71	259.00
IUUC-Tme-126912	Tuber melanosporum	82.31	1.00e-74	269.00
IUUC-Tbe-127329	Tupaia belangeri	71.43	3.00e-60	221.00
IUUC-Ttr-128363	Tursiops truncatus	78.23	8.00e-69	249.00
IUUC-Uma-129648	Ustilago maydis	79.59	5.00e-73	263.00
IUUC-Vda-129695	Verticillium dahliae	82.99	9.00e-76	273.00
IUUC-Vpa-130446	Vicugna pacos	75.51	1.00e-65	240.00
IUUC-Vvi-131016	Vitis vinifera	80.27	4.00e-72	260.00
IUUC-Xtr-132238	Xenopus tropicalis	77.55	1.00e-69	252.00
IUUC-Xma-133762	Xiphophorus maculatus	76.87	4.00e-69	250.00
IUUC-Yli-134353	Yarrowia lipolytica	82.31	1.00e-73	265.00
IUUC-Zma-134742	Zea mays	78.91	1.00e-70	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence