iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d034640	Zm00001d034640_T026	Zm00001d034640_T026
Zm00001d034640	Zm00001d034640_T027	Zm00001d034640_T027
Zm00001d034640	Zm00001d034640_T033	Zm00001d034640_T033
Zm00001d034640	Zm00001d034640_T035	Zm00001d034640_T035
Zm00001d034640	Zm00001d034640_T013	Zm00001d034640_T013
Zm00001d034640	Zm00001d034640_T003	Zm00001d034640_T003
Zm00001d034640	Zm00001d034640_T028	Zm00001d034640_T028
Zm00001d034640	Zm00001d034640_T018	Zm00001d034640_T018
Zm00001d034640	Zm00001d034640_T016	Zm00001d034640_T016
Zm00001d034640	Zm00001d034640_T002	Zm00001d034640_T002
Zm00001d034640	Zm00001d034640_T034	Zm00001d034640_T034
Zm00001d034640	Zm00001d034640_T017	Zm00001d034640_T017

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.20e-108	363.5	14	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnv 90
           YDRQ+r+wG+++q++l++a+++l+++g++G+E lKnLvl+G+gs+tvvD+++ve s+l+++FL+++   g+++A++ + +l+eln+ v++
   Q: 14   YDRQLRIWGDQGQAALEKASICLLNCGPTGTEALKNLVLGGIGSVTVVDGSKVESSDLGNNFLLDEGCLGQPRAKSICSFLQELNDAVKA 103
           ****************************************************************************************** PP
   S: 91   eaheesiteleeeiv.FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd...dppqktiPfctl 176
           +++ees+  l ++++ Ff++f+vV++++ +++  +k++ +c++a++ l+ ++++Gl G vrv++k++ +++s++d   d++++ +P+ +l
   Q: 104  KFVEESPAHLIDTNPsFFSQFTVVIATQLPESFLLKLDYICRKADIVLVAARSYGLTGLVRVSVKEHCVIESKPDhflDDLRLHNPWTEL 193
           ****************************************************************************************** PP
   S: 177  ketpn.........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikql 256
           k++           ++++ ++++v++  l+e++a +++++ +++++ek+e+kd++++ + + deen++ea+  + k   +  in+ i+q+
   Q: 194  KQFAKsidindkdpVVHKNTPYIVILVRLAEKWADAHDGNLPSTRQEKKEFKDLIRAHMLNVDEENYKEAVDSSYKVSVTPGINNeIRQI 283
           ***88899999999**************************************************************************** PP
   S: 257  lksfecdivtkskspfwv........................................................................ 274
           +++   ++v++s+s+fw+                                                                        
   Q: 284  IDD-DSAEVNSSSSDFWIlvaalkefiakegngelplegtipdmtslteyyvslqkiyqakaefdclalehhvkeilkrigrdpdsisra 372
           ***.56699********************************************************************************* PP
   S: 275  ...sfcsnaealqvp...........ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlrae 345
              +fc+n+++l+v            + v + +++++++++     +y+llra++r++++++r pg ++ e d+d +++l+t aa+  a+
   Q: 373  yikTFCKNSRKLRVSryrsfeeefssPFVPEIQRYFTDEDYsyatnFYILLRAVDRLAANYSRLPGIFDSEIDED-IPRLKTVAAS-VAS 460
           *************66666666666669999******9999999***********************999999999.9999997776.57* PP
   S: 346  slgiep.kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
           ++g+++  l++dli+e+++++ ++i++++a+vgG+a+qEviK+v+++f+pl  +f+f+++
   Q: 461  EMGLNGaSLSEDLITEMCRFGGAEIHPVAAFVGGVASQEVIKLVTKQFVPLPGTFIFNGI 520
           *********************************************************986 PP

Organism

Zea mays

Functional Description
(View)

Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1.

Protein Sequence
(Fasta)

MAATGVVAEP KTKYDRQLRI WGDQGQAALE KASICLLNCG PTGTEALKNL VLGGIGSVTV 60
VDGSKVESSD LGNNFLLDEG CLGQPRAKSI CSFLQELNDA VKAKFVEESP AHLIDTNPSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGTCGCTA TATTCCTCGC CGGAGTGTAG CGGGGCGAAG CCATCCGAAC TCCGAAAAGC 60
CCCCCAGCGG CCTCCCCTCC GCCCCGCAGC CATGGCCGCC ACCGGCGTGG TCGCCGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007900	Ashbya gossypii	27.26	5.00e-41	161.00
IUUC-Acl-008333	Aspergillus clavatus	33.15	1.00e-69	256.00
IUUC-Afu-009071	Aspergillus fumigatus	32.55	6.00e-67	248.00
IUUC-Bgr-012111	Blumeria graminis	32.66	1.00e-61	229.00
IUUC-Bra-017506	Brassica rapa	65.14	0.00e+00	733.00
IUUC-Cel-018456	Caenorhabditis elegans	30.70	1.00e-71	263.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	29.96	6.00e-58	218.00
IUUC-Cne-026884	Cryptococcus neoformans	31.67	9.00e-68	250.00
IUUC-Dor-030513	Dipodomys ordii	54.05	2.00e-28	119.00
IUUC-Dme-031683	Drosophila melanogaster	38.07	2.00e-101	362.00
IUUC-Ggr-040005	Gaeumannomyces graminis	34.67	1.00e-54	207.00
IUUC-Gga-041129	Gallus gallus	42.62	8.00e-122	430.00
IUUC-Gma-043610	Glycine max	69.41	0.00e+00	758.00
IUUC-Lpe-051535	Leersia perrieri	84.41	0.00e+00	828.00
IUUC-Mor-057230	Magnaporthe oryzae	32.16	2.00e-66	245.00
IUUC-Mac-064521	Musa acuminata	72.68	0.00e+00	822.00
IUUC-Nfi-068245	Neosartorya fischeri	32.15	1.00e-67	250.00
IUUC-Obr-076684	Oryza brachyantha	87.86	0.00e+00	842.00
IUUC-Ogu-078844	Oryza glumaepatula	87.93	0.00e+00	847.00
IUUC-Oin-079105	Oryza indica	88.68	0.00e+00	895.00
IUUC-Oru-084960	Oryza rufipogon	85.26	0.00e+00	822.00
IUUC-Osa-085358	Oryza sativa	88.48	0.00e+00	891.00
IUUC-Ppa-095798	Physcomitrella patens	55.28	9.00e-177	612.00
IUUC-Pca-100807	Procavia capensis	52.41	4.00e-54	204.00
IUUC-Ppe-101280	Prunus persica	68.26	0.00e+00	773.00
IUUC-Pgr-103401	Puccinia graminis	30.52	6.00e-72	264.00
IUUC-Pte-104355	Pyrenophora teres	33.63	3.00e-71	262.00
IUUC-Sha-106770	Sarcophilus harrisii	50.38	1.00e-71	262.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	33.20	7.00e-79	287.00
IUUC-Sit-110157	Setaria italica	91.30	0.00e+00	1004.00
IUUC-Sly-111105	Solanum lycopersicum	66.11	0.00e+00	756.00
IUUC-Stu-112469	Solanum tuberosum	66.67	0.00e+00	764.00
IUUC-Sbi-113813	Sorghum bicolor	96.79	0.00e+00	1056.00
IUUC-Sre-115058	Sporisorium reilianum	34.99	4.00e-66	245.00
IUUC-Tru-118686	Takifugu rubripes	41.45	1.00e-124	439.00
IUUC-Tca-121491	Theobroma cacao	68.83	0.00e+00	744.00
IUUC-Tre-122103	Trichoderma reesei	33.21	2.00e-75	276.00
IUUC-Tvi-122672	Trichoderma virens	32.52	6.00e-68	251.00
IUUC-Tae-125316	Triticum aestivum	87.72	0.00e+00	929.00
IUUC-Tur-126487	Triticum urartu	86.27	0.00e+00	899.00
IUUC-Tme-127097	Tuber melanosporum	34.44	7.00e-79	287.00
IUUC-Uma-129645	Ustilago maydis	30.14	6.00e-68	251.00
IUUC-Vda-129989	Verticillium dahliae	29.85	9.00e-51	194.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence