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Tag Content
UUCD2 ID IUUC-Pab-098250
UUCD1 version UUC-PoA-00127
Ensembl Protein ID ENSPPYP00000003692.2
UniProt Accession H2ND95; H2ND95_PONAB
Genbank Protein ID ENSPPYP00000003692
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01399834
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000003202.2 ENSPPYT00000003824.2 ENSPPYP00000003692.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.70e-15 56.9 3 64
E3 adaptor/Cullin RING/DCX/DWD 1.50e-29 100.9 390 423
UBD/Beta-Prp 3.90e-49 167.5 231 461
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++C+Is+e++++P+v+p s+++y+r+ Iek++a++g+ +P+++qpl+ee+l++ ++ + +  +
   Q: 3    LICSISNEVPEHPCVSPvSNHVYERRLIEKYIAENGT-DPINNQPLSEEQLIDIKVAHPIRPK 64
           79**********************************9.***************9998877665 PP
   

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 390  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 423
           8**********976699**************986 PP
   

   UBD/Beta-Prp
   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ + v+d ++++ l++l+gh+++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd
   Q: 231  PSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 319
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l
   Q: 320  YLLSSSDDQYWAFSDIQTGRVLTKvTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYL 407
           **********************997777777789************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           +++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 408  ATAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 461
           ***************999999999866527********************9998 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MSLICSISNE VPEHPCVSPV SNHVYERRLI EKYIAENGTD PINNQPLSEE QLIDIKVAHP 60
IRPKPPSATS IPAILKALQD EWDAVMLHSF TLRQQLQTTR QELSHALYQH DAACRVIARL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098250|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTCGTGGCGG GCCCTTTCCT GCCCGACTGC ATTCTGGGAA AGAGCAATTT CCGTTAGGTG 60
CTGAAGGCTG TGGCGCGCGG CTGTCCCCAT TCCCACGTGA AGCGCTGCGC TAGCATCGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098250|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001480--Bulb-type_lectin_dom
IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 39.51 1.00e-92 335.00
IUUC-Aml-001230 Ailuropoda melanoleuca 94.46 0.00e+00 905.00
IUUC-Atr-002594 Amborella trichopoda 44.91 2.00e-116 412.00
IUUC-Apl-003686 Anas platyrhynchos 87.85 0.00e+00 729.00
IUUC-Aca-005272 Anolis carolinensis 95.88 0.00e+00 936.00
IUUC-Aly-005586 Arabidopsis lyrata 44.40 3.00e-115 408.00
IUUC-Ath-007696 Arabidopsis thaliana 44.53 5.00e-111 394.00
IUUC-Acl-008335 Aspergillus clavatus 35.79 3.00e-68 252.00
IUUC-Afl-008527 Aspergillus flavus 38.19 3.00e-73 268.00
IUUC-Afu-008957 Aspergillus fumigatus 38.32 5.00e-79 288.00
IUUC-Ani-009280 Aspergillus nidulans 38.45 6.00e-67 248.00
IUUC-Ang-009746 Aspergillus niger 36.50 3.00e-67 249.00
IUUC-Aor-009905 Aspergillus oryzae 37.97 9.00e-77 280.00
IUUC-Ate-010412 Aspergillus terreus 37.97 8.00e-66 244.00
IUUC-Ame-011561 Astyanax mexicanus 85.00 5.00e-111 393.00
IUUC-Bgr-012283 Blumeria graminis 32.85 1.00e-56 213.00
IUUC-Bta-013242 Bos taurus 98.14 0.00e+00 949.00
IUUC-Bci-013901 Botrytis cinerea 35.09 8.00e-65 241.00
IUUC-Bdi-014277 Brachypodium distachyon 43.89 7.00e-119 420.00
IUUC-Bol-016207 Brassica oleracea 45.95 2.00e-114 405.00
IUUC-Bra-017902 Brassica rapa 43.79 3.00e-112 398.00
IUUC-Cel-018271 Caenorhabditis elegans 51.98 6.00e-144 503.00
IUUC-Cja-019879 Callithrix jacchus 97.94 0.00e+00 944.00
IUUC-Cfa-020175 Canis familiaris 97.73 0.00e+00 946.00
IUUC-Cpo-022379 Cavia porcellus 97.94 0.00e+00 948.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 41.54 3.00e-97 348.00
IUUC-Csa-023500 Chlorocebus sabaeus 98.35 0.00e+00 951.00
IUUC-Cho-025065 Choloepus hoffmanni 88.10 5.00e-149 520.00
IUUC-Cin-025699 Ciona intestinalis 68.35 1.00e-175 608.00
IUUC-Csv-026128 Ciona savignyi 65.64 0.00e+00 639.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 34.32 3.00e-65 242.00
IUUC-Cne-026860 Cryptococcus neoformans 38.32 2.00e-88 319.00
IUUC-Dre-028187 Danio rerio 84.49 0.00e+00 803.00
IUUC-Dno-029453 Dasypus novemcinctus 98.14 0.00e+00 949.00
IUUC-Dor-030150 Dipodomys ordii 99.16 3.00e-128 451.00
IUUC-Dse-031220 Dothistroma septosporum 32.49 1.00e-58 220.00
IUUC-Dme-031906 Drosophila melanogaster 66.24 3.00e-179 621.00
IUUC-Ete-033035 Echinops telfairi 84.74 0.00e+00 795.00
IUUC-Eca-033478 Equus caballus 97.94 0.00e+00 947.00
IUUC-Eeu-034974 Erinaceus europaeus 97.10 2.00e-178 618.00
IUUC-Fca-036194 Felis catus 96.89 0.00e+00 936.00
IUUC-Fal-037417 Ficedula albicollis 95.46 0.00e+00 932.00
IUUC-Fox-037922 Fusarium oxysporum 34.72 4.00e-64 238.00
IUUC-Fso-038256 Fusarium solani 34.73 1.00e-65 243.00
IUUC-Gmo-038713 Gadus morhua 86.79 0.00e+00 828.00
IUUC-Ggr-039854 Gaeumannomyces graminis 33.27 1.00e-53 204.00
IUUC-Gga-041143 Gallus gallus 95.88 0.00e+00 935.00
IUUC-Gac-042129 Gasterosteus aculeatus 85.53 0.00e+00 843.00
IUUC-Gma-044273 Glycine max 46.14 2.00e-116 412.00
IUUC-Ggo-045262 Gorilla gorilla 98.35 0.00e+00 951.00
IUUC-Hsa-046036 Homo sapiens 98.35 0.00e+00 951.00
IUUC-Hvu-047442 Hordeum vulgare 42.81 2.00e-68 252.00
IUUC-Itr-048169 Ictidomys tridecemlineatus 97.73 0.00e+00 907.00
IUUC-Lch-050105 Latimeria chalumnae 90.13 0.00e+00 882.00
IUUC-Lpe-050976 Leersia perrieri 44.72 2.00e-114 405.00
IUUC-Loc-052042 Lepisosteus oculatus 73.70 2.00e-176 611.00
IUUC-Lma-053143 Leptosphaeria maculans 34.38 1.00e-64 241.00
IUUC-Laf-053451 Loxodonta africana 94.62 0.00e+00 937.00
IUUC-Mcc-055786 Macaca mulatta 98.35 0.00e+00 951.00
IUUC-Meu-056161 Macropus eugenii 99.17 8.00e-141 493.00
IUUC-Mor-057215 Magnaporthe oryzae 34.51 1.00e-56 214.00
IUUC-Mpo-057419 Magnaporthe poae 32.24 6.00e-50 191.00
IUUC-Mtr-057756 Medicago truncatula 44.38 1.00e-111 396.00
IUUC-Mla-059085 Melampsora laricipopulina 38.16 5.00e-82 298.00
IUUC-Mga-060158 Meleagris gallopavo 91.86 0.00e+00 868.00
IUUC-Mvi-060441 Microbotryum violaceum 38.24 3.00e-73 269.00
IUUC-Mmr-061085 Microcebus murinus 98.35 0.00e+00 951.00
IUUC-Mdo-061804 Monodelphis domestica 97.94 0.00e+00 948.00
IUUC-Mmu-063608 Mus musculus 94.05 0.00e+00 932.00
IUUC-Mac-064972 Musa acuminata 44.51 6.00e-112 397.00
IUUC-Mpu-065700 Mustela putorius furo 97.73 0.00e+00 947.00
IUUC-Mlu-068223 Myotis lucifugus 94.50 0.00e+00 926.00
IUUC-Nfi-068504 Neosartorya fischeri 37.76 1.00e-78 286.00
IUUC-Ncr-068729 Neurospora crassa 36.90 1.00e-63 236.00
IUUC-Nle-069754 Nomascus leucogenys 98.35 0.00e+00 951.00
IUUC-Opr-070621 Ochotona princeps 100.00 0.00e+00 933.00
IUUC-Ont-071377 Oreochromis niloticus 85.32 0.00e+00 820.00
IUUC-Oan-073498 Ornithorhynchus anatinus 73.23 1.00e-122 432.00
IUUC-Ocu-074182 Oryctolagus cuniculus 94.27 0.00e+00 938.00
IUUC-Oba-075509 Oryza barthii 43.81 5.00e-116 411.00
IUUC-Obr-076480 Oryza brachyantha 44.83 4.00e-117 414.00
IUUC-Ogl-077052 Oryza glaberrima 43.81 5.00e-116 411.00
IUUC-Ogu-078919 Oryza glumaepatula 43.81 5.00e-116 411.00
IUUC-Oin-079357 Oryza indica 43.06 3.00e-109 388.00
IUUC-Olo-080376 Oryza longistaminata 43.57 4.00e-104 371.00
IUUC-Ome-081973 Oryza meridionalis 43.04 5.00e-104 371.00
IUUC-Oni-082849 Oryza nivara 44.02 7.00e-117 414.00
IUUC-Opu-083243 Oryza punctata 43.81 7.00e-116 410.00
IUUC-Oru-084613 Oryza rufipogon 44.11 4.00e-116 411.00
IUUC-Osa-085407 Oryza sativa 43.81 5.00e-116 411.00
IUUC-Ola-086566 Oryzias latipes 84.27 0.00e+00 812.00
IUUC-Olu-087757 Ostreococcus lucimarinus 40.52 1.00e-93 336.00
IUUC-Oga-089010 Otolemur garnettii 93.44 0.00e+00 896.00
IUUC-Oar-089638 Ovis aries 98.14 0.00e+00 949.00
IUUC-Ptr-091141 Pan troglodytes 98.35 0.00e+00 951.00
IUUC-Pan-092662 Papio anubis 98.35 0.00e+00 951.00
IUUC-Psi-093777 Pelodiscus sinensis 95.25 0.00e+00 758.00
IUUC-Pno-095115 Phaeosphaeria nodorum 35.08 4.00e-65 241.00
IUUC-Ppa-095841 Physcomitrella patens 45.73 2.00e-117 416.00
IUUC-Pfo-096390 Poecilia formosa 84.70 0.00e+00 820.00
IUUC-Pop-099854 Populus trichocarpa 45.47 6.00e-116 410.00
IUUC-Pca-100553 Procavia capensis 97.73 0.00e+00 941.00
IUUC-Ppe-101383 Prunus persica 43.95 1.00e-108 387.00
IUUC-Pva-102189 Pteropus vampyrus 97.94 0.00e+00 948.00
IUUC-Pgr-103304 Puccinia graminis 37.25 3.00e-80 292.00
IUUC-Ptt-103984 Puccinia triticina 38.16 1.00e-85 310.00
IUUC-Pte-104385 Pyrenophora teres 33.19 7.00e-69 254.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 33.62 2.00e-70 259.00
IUUC-Rno-105581 Rattus norvegicus 97.73 0.00e+00 946.00
IUUC-Sha-107071 Sarcophilus harrisii 93.69 0.00e+00 934.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 31.34 3.00e-35 142.00
IUUC-Spo-108315 Schizosaccharomyces pombe 32.40 1.00e-45 177.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 35.16 2.00e-64 239.00
IUUC-Smo-109648 Selaginella moellendorffii 45.40 1.00e-118 419.00
IUUC-Sit-109873 Setaria italica 43.81 4.00e-114 405.00
IUUC-Sly-111673 Solanum lycopersicum 45.75 7.00e-109 387.00
IUUC-Stu-112125 Solanum tuberosum 45.55 4.00e-108 384.00
IUUC-Sbi-114696 Sorghum bicolor 42.32 2.00e-102 365.00
IUUC-Sre-115134 Sporisorium reilianum 32.70 1.00e-70 260.00
IUUC-Ssc-116260 Sus scrofa 98.14 0.00e+00 949.00
IUUC-Tgu-116533 Taeniopygia guttata 95.88 0.00e+00 935.00
IUUC-Tru-117800 Takifugu rubripes 84.91 0.00e+00 845.00
IUUC-Tsy-118980 Tarsius syrichta 92.26 0.00e+00 870.00
IUUC-Tni-120334 Tetraodon nigroviridis 80.32 4.00e-158 550.00
IUUC-Tca-121807 Theobroma cacao 44.47 3.00e-116 412.00
IUUC-Tre-121920 Trichoderma reesei 33.40 4.00e-63 235.00
IUUC-Tvi-122294 Trichoderma virens 33.05 1.00e-55 210.00
IUUC-Tae-125713 Triticum aestivum 44.09 2.00e-119 422.00
IUUC-Tur-126664 Triticum urartu 39.67 2.00e-109 389.00
IUUC-Tme-127026 Tuber melanosporum 34.24 7.00e-68 251.00
IUUC-Tbe-127582 Tupaia belangeri 97.42 9.00e-178 616.00
IUUC-Ttr-128313 Tursiops truncatus 97.73 0.00e+00 939.00
IUUC-Uma-129626 Ustilago maydis 34.62 2.00e-72 266.00
IUUC-Vda-129699 Verticillium dahliae 35.36 1.00e-67 250.00
IUUC-Vpa-130593 Vicugna pacos 99.12 0.00e+00 900.00
IUUC-Vvi-131668 Vitis vinifera 44.35 3.00e-115 408.00
IUUC-Xtr-132186 Xenopus tropicalis 85.42 0.00e+00 768.00
IUUC-Xma-133212 Xiphophorus maculatus 84.49 0.00e+00 815.00
IUUC-Yli-134607 Yarrowia lipolytica 57.58 3.00e-41 160.00
IUUC-Zma-135662 Zea mays 45.12 3.00e-116 411.00
Created Date 25-Jun-2017

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