iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Obr-076755

Ensembl Protein ID

OB12G10440.1

UniProt Accession

J3NAN6; J3NAN6_ORYBR

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OB12G10440	OB12G10440.1	OB12G10440.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.10e-154	516.2	440	733

Active Site

Position(s)	Description	Evidence
621	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnvea 92
           YD Qi ++G++ q+kl++ak+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLfr++++g++K+ vaa a+  +np+ +ve+
   Q: 440  YDAQISVFGSKLQRKLEQAKIFMVGSGALGCEFLKNLALMGIscsenGKLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMAINPKLHVEV 536
           ************************************************************************************************* PP
   S: 93   heesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeht 186
            +++ ++++e+++   F + +d Vv+aldn+ ar++++++c++ ++ l+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+
   Q: 537  LQNRASPETENVFndaFWEGLDAVVNALDNVTARMYIDSRCVYFQKALLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHC 633
           ***********99999********************************************************************************* PP
   S: 187  iewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtksksp 271
           ++wa              +n +l++ +g ++ +     ++ ++ +++v + l+ e+ e+f+++i++a+ +f+ +++n +kql+  f+ d +t+s++p
   Q: 634  LTWArsefegllektpTEVNAFLSNPSGYSTAARTAGDAQARDQLERVIECLEREKCETFQDCITWARLKFEDYFSNRVKQLTFTFPEDAMTSSGAP 730
           ***************9999****************************************************************************** PP
   S: 272  fwv 274
           fw+
   Q: 731  FWS 733
           **7 PP

Organism

Oryza brachyantha

Protein Sequence
(Fasta)

MLTRKREELA DDVDDLQKKT RADAKDNHDM TTGRTPEIDE DLHSRQLAVY GRETMKRLFA 60
SNVLVSGLNG LGAEIAKNLV LAGVKSVTLH DDDKVDLWDL SSNFFLSEND VGQNRAQACI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAGAGAA GAGAAGAGAA GGATTAGAAG AAGAAGAATT TACAGTTTAG CCCTCCCCTC 60
CAAGAAAACC CTAGCTAGCT ATCGGAAGAG AAGCGAAGAA GAAGATCAGG TAGAGTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR011009--Kinase-like_dom
IPR016040--NAD(P)-bd_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000594--ThiF_NAD_FAD-bd
IPR020635--Tyr_kinase_cat_dom
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF07714--Pkinase_Tyr
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00219--TyrKc

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0004713--F:protein tyrosine kinase activity
GO:0008641--F:small protein activating enzyme activity

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence