iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004683

UUCD1 version

UUC-AnC-00825

Ensembl Protein ID

ENSACAP00000015452.3

UniProt Accession

G1KRH3; G1KRH3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015703.3	ENSACAT00000015766.3	ENSACAP00000015452.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-45	151.3	204	240
UBD/Beta-Prp	4.80e-65	219.6	300	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 204  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 240
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           p  ++l+t srd+t ++wdv+t+  +++lsgh+++v++vk++  ++ ++tgs D ti++wdl +gk+ +tl++h++sv+++ ++p +++
   Q: 300  PTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVKCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRQYT 388
           55567777888888888888887778888888888888888888778888888888888888888888888888888888888887788 PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.......tgghtdsvyslsfds 190
           ++sGs d+ i+ w+ + g  ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++        + + ++ + s +fd+
   Q: 389  FASGSPDN-IKQWKFPDGNFIQ-NLSGHNAIINTLAVNS-DGVLVSGADNGTMHLWDWRTGYNFQRVhaavqpgSLDSESGIFSCAFDQ 474
           88888554.7888888888887.7888888888888877.5677788888888888887777777776666666334666677777888 PP
   S: 191  ngkelvsgsldgtvklwd 208
           +  +l+++  d+t+k++ 
   Q: 475  SESRLLTAEADKTIKVYR 492
           778888888888888775 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADNA KPVSLDEKSH KIKMAVKLRV EYSSVLHMPV 60
IKENTRDKGS HGAIDSYGHK QYLQNSGDDN EYLITGTHPY PPGPGVALTA DTKIQRMPSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTAGAAT TTTAAAATAT TGCTAGCCAG ATTTCGTTCA TTTTCATGGA TTCCTCCTTC 60
CTTTTGAAAC TGTCCACATG CTTGTGGATT TCAATGCATT CTCTGTGTAG TCTAACACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus

KEGG

acs:100552926

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	46.08	2.00e-128	452.00
IUUC-Aml-001605	Ailuropoda melanoleuca	89.30	0.00e+00	956.00
IUUC-Atr-002757	Amborella trichopoda	47.96	4.00e-129	454.00
IUUC-Apl-003198	Anas platyrhynchos	91.09	0.00e+00	992.00
IUUC-Aly-005775	Arabidopsis lyrata	60.36	2.00e-125	442.00
IUUC-Ath-007460	Arabidopsis thaliana	52.71	5.00e-125	441.00
IUUC-Ago-007884	Ashbya gossypii	48.85	2.00e-106	378.00
IUUC-Acl-008153	Aspergillus clavatus	64.33	5.00e-129	454.00
IUUC-Afl-008384	Aspergillus flavus	57.14	2.00e-130	458.00
IUUC-Afu-009045	Aspergillus fumigatus	65.55	1.00e-130	459.00
IUUC-Ani-009229	Aspergillus nidulans	62.50	7.00e-130	456.00
IUUC-Ang-009812	Aspergillus niger	65.30	8.00e-124	436.00
IUUC-Aor-010059	Aspergillus oryzae	57.14	2.00e-130	458.00
IUUC-Ate-010351	Aspergillus terreus	63.08	9.00e-136	476.00
IUUC-Ame-011613	Astyanax mexicanus	60.49	8.00e-162	563.00
IUUC-Bgr-012042	Blumeria graminis	55.56	4.00e-135	474.00
IUUC-Bta-012406	Bos taurus	88.37	0.00e+00	945.00
IUUC-Bci-013760	Botrytis cinerea	59.21	7.00e-135	473.00
IUUC-Bdi-014776	Brachypodium distachyon	56.96	2.00e-131	461.00
IUUC-Bol-016189	Brassica oleracea	60.66	8.00e-126	443.00
IUUC-Bra-018044	Brassica rapa	60.66	8.00e-126	443.00
IUUC-Cel-018651	Caenorhabditis elegans	52.22	9.00e-154	536.00
IUUC-Cja-019974	Callithrix jacchus	88.57	0.00e+00	947.00
IUUC-Cfa-021085	Canis familiaris	89.34	0.00e+00	960.00
IUUC-Cpo-021458	Cavia porcellus	88.18	0.00e+00	951.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.88	2.00e-124	438.00
IUUC-Csa-023883	Chlorocebus sabaeus	88.37	0.00e+00	945.00
IUUC-Cho-024623	Choloepus hoffmanni	87.87	0.00e+00	927.00
IUUC-Cin-025190	Ciona intestinalis	60.08	0.00e+00	636.00
IUUC-Csv-026367	Ciona savignyi	60.00	0.00e+00	644.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	66.26	7.00e-140	490.00
IUUC-Cne-027069	Cryptococcus neoformans	50.10	8.00e-129	453.00
IUUC-Cme-027233	Cyanidioschyzon merolae	30.75	2.00e-35	142.00
IUUC-Dre-028260	Danio rerio	81.24	0.00e+00	884.00
IUUC-Dno-029112	Dasypus novemcinctus	89.53	0.00e+00	957.00
IUUC-Dor-031118	Dipodomys ordii	90.75	0.00e+00	775.00
IUUC-Dse-031493	Dothistroma septosporum	59.59	1.00e-124	439.00
IUUC-Dme-032138	Drosophila melanogaster	76.31	1.00e-159	555.00
IUUC-Ete-032411	Echinops telfairi	78.36	0.00e+00	761.00
IUUC-Eca-033521	Equus caballus	89.34	0.00e+00	963.00
IUUC-Eeu-035249	Erinaceus europaeus	78.83	0.00e+00	651.00
IUUC-Fca-036358	Felis catus	88.76	0.00e+00	954.00
IUUC-Fal-036933	Ficedula albicollis	90.70	0.00e+00	984.00
IUUC-Fox-037713	Fusarium oxysporum	56.02	6.00e-138	483.00
IUUC-Fso-038380	Fusarium solani	63.45	3.00e-138	484.00
IUUC-Gmo-039133	Gadus morhua	82.26	0.00e+00	891.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.67	2.00e-132	465.00
IUUC-Gga-041176	Gallus gallus	90.50	0.00e+00	989.00
IUUC-Gac-042344	Gasterosteus aculeatus	79.84	0.00e+00	878.00
IUUC-Gma-043328	Glycine max	48.53	4.00e-131	461.00
IUUC-Ggo-044478	Gorilla gorilla	88.18	0.00e+00	942.00
IUUC-Hsa-046037	Homo sapiens	88.37	0.00e+00	944.00
IUUC-Hvu-047349	Hordeum vulgare	49.08	2.00e-132	465.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	89.15	0.00e+00	958.00
IUUC-Kpa-049343	Komagataella pastoris	58.46	3.00e-119	421.00
IUUC-Lch-049830	Latimeria chalumnae	86.63	0.00e+00	945.00
IUUC-Lpe-051442	Leersia perrieri	47.24	3.00e-130	458.00
IUUC-Loc-051794	Lepisosteus oculatus	84.91	0.00e+00	897.00
IUUC-Lma-053137	Leptosphaeria maculans	45.54	7.00e-128	450.00
IUUC-Laf-053471	Loxodonta africana	88.52	0.00e+00	950.00
IUUC-Mcc-055627	Macaca mulatta	88.37	0.00e+00	947.00
IUUC-Meu-056148	Macropus eugenii	80.31	0.00e+00	855.00
IUUC-Mor-056960	Magnaporthe oryzae	63.74	2.00e-137	482.00
IUUC-Mtr-057816	Medicago truncatula	60.66	1.00e-126	446.00
IUUC-Mla-059031	Melampsora laricipopulina	65.72	7.00e-128	450.00
IUUC-Mga-059337	Meleagris gallopavo	90.66	0.00e+00	988.00
IUUC-Mvi-060217	Microbotryum violaceum	65.09	3.00e-130	458.00
IUUC-Mmr-061018	Microcebus murinus	89.92	0.00e+00	967.00
IUUC-Mdo-062863	Monodelphis domestica	92.44	0.00e+00	979.00
IUUC-Mmu-063988	Mus musculus	87.98	0.00e+00	937.00
IUUC-Mac-064459	Musa acuminata	63.99	5.00e-122	431.00
IUUC-Mpu-066559	Mustela putorius furo	89.53	0.00e+00	962.00
IUUC-Mlu-067361	Myotis lucifugus	88.69	0.00e+00	937.00
IUUC-Nfi-068492	Neosartorya fischeri	65.85	9.00e-131	459.00
IUUC-Ncr-068808	Neurospora crassa	57.11	9.00e-138	483.00
IUUC-Nle-069875	Nomascus leucogenys	88.57	0.00e+00	946.00
IUUC-Opr-070462	Ochotona princeps	96.24	6.00e-155	540.00
IUUC-Ont-071365	Oreochromis niloticus	79.65	0.00e+00	882.00
IUUC-Oan-072708	Ornithorhynchus anatinus	92.02	0.00e+00	1001.00
IUUC-Ocu-074594	Oryctolagus cuniculus	88.37	0.00e+00	948.00
IUUC-Oba-075570	Oryza barthii	62.46	2.00e-127	448.00
IUUC-Obr-076366	Oryza brachyantha	64.83	8.00e-93	332.00
IUUC-Ogl-077153	Oryza glaberrima	62.46	1.00e-126	446.00
IUUC-Ogu-078540	Oryza glumaepatula	62.46	2.00e-127	448.00
IUUC-Oin-079612	Oryza indica	61.54	2.00e-125	442.00
IUUC-Olo-081077	Oryza longistaminata	61.54	2.00e-125	442.00
IUUC-Ome-081236	Oryza meridionalis	61.24	3.00e-125	441.00
IUUC-Oni-082499	Oryza nivara	62.46	2.00e-127	448.00
IUUC-Opu-083499	Oryza punctata	61.54	2.00e-125	442.00
IUUC-Oru-084276	Oryza rufipogon	62.46	2.00e-127	448.00
IUUC-Osa-085849	Oryza sativa	62.46	2.00e-127	448.00
IUUC-Ola-086655	Oryzias latipes	77.95	0.00e+00	852.00
IUUC-Olu-087637	Ostreococcus lucimarinus	58.97	6.00e-119	420.00
IUUC-Oga-087934	Otolemur garnettii	89.56	0.00e+00	960.00
IUUC-Oar-090185	Ovis aries	87.81	0.00e+00	938.00
IUUC-Ptr-091198	Pan troglodytes	88.57	0.00e+00	946.00
IUUC-Pan-092622	Papio anubis	88.37	0.00e+00	945.00
IUUC-Psi-093320	Pelodiscus sinensis	91.68	0.00e+00	995.00
IUUC-Pma-094638	Petromyzon marinus	79.22	0.00e+00	866.00
IUUC-Pno-094826	Phaeosphaeria nodorum	50.74	5.00e-105	374.00
IUUC-Ppa-095576	Physcomitrella patens	63.67	3.00e-124	438.00
IUUC-Pfo-096894	Poecilia formosa	79.34	0.00e+00	866.00
IUUC-Pab-098020	Pongo abelii	88.57	0.00e+00	946.00
IUUC-Pop-099180	Populus trichocarpa	48.54	6.00e-127	447.00
IUUC-Pca-100909	Procavia capensis	83.07	0.00e+00	745.00
IUUC-Ppe-101346	Prunus persica	54.71	5.00e-124	437.00
IUUC-Pva-102167	Pteropus vampyrus	74.22	0.00e+00	752.00
IUUC-Pgr-103516	Puccinia graminis	65.72	3.00e-129	454.00
IUUC-Ptt-103738	Puccinia triticina	50.84	2.00e-129	455.00
IUUC-Pte-104352	Pyrenophora teres	58.11	2.00e-130	458.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	58.70	3.00e-131	461.00
IUUC-Rno-105291	Rattus norvegicus	88.37	0.00e+00	944.00
IUUC-Sce-106204	Saccharomyces cerevisiae	49.55	5.00e-103	367.00
IUUC-Sha-106943	Sarcophilus harrisii	91.68	0.00e+00	970.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	64.76	3.00e-129	454.00
IUUC-Spo-108049	Schizosaccharomyces pombe	49.51	4.00e-136	477.00
IUUC-Smo-109043	Selaginella moellendorffii	60.78	3.00e-126	444.00
IUUC-Sit-110431	Setaria italica	57.36	2.00e-131	462.00
IUUC-Sly-111391	Solanum lycopersicum	61.66	4.00e-119	421.00
IUUC-Stu-112364	Solanum tuberosum	55.26	2.00e-96	345.00
IUUC-Sar-113450	Sorex araneus	96.28	0.00e+00	710.00
IUUC-Sbi-113829	Sorghum bicolor	49.19	1.00e-130	459.00
IUUC-Sre-115153	Sporisorium reilianum	61.85	3.00e-122	431.00
IUUC-Ssc-115798	Sus scrofa	88.59	0.00e+00	948.00
IUUC-Tgu-117417	Taeniopygia guttata	91.42	0.00e+00	990.00
IUUC-Tru-117615	Takifugu rubripes	77.97	0.00e+00	820.00
IUUC-Tsy-119480	Tarsius syrichta	89.08	0.00e+00	945.00
IUUC-Tni-119847	Tetraodon nigroviridis	78.10	0.00e+00	851.00
IUUC-Tca-121287	Theobroma cacao	47.06	1.00e-128	453.00
IUUC-Tre-122010	Trichoderma reesei	65.50	3.00e-143	501.00
IUUC-Tvi-122475	Trichoderma virens	64.33	7.00e-142	496.00
IUUC-Tae-124397	Triticum aestivum	49.29	6.00e-134	470.00
IUUC-Tur-126116	Triticum urartu	49.87	9.00e-101	360.00
IUUC-Tme-126992	Tuber melanosporum	65.24	4.00e-136	478.00
IUUC-Tbe-127803	Tupaia belangeri	79.72	0.00e+00	692.00
IUUC-Ttr-128933	Tursiops truncatus	88.76	0.00e+00	949.00
IUUC-Uma-129447	Ustilago maydis	60.00	4.00e-118	418.00
IUUC-Vda-129780	Verticillium dahliae	62.46	3.00e-138	484.00
IUUC-Vpa-130557	Vicugna pacos	76.62	4.00e-100	358.00
IUUC-Vvi-130918	Vitis vinifera	53.63	4.00e-121	427.00
IUUC-Xtr-132409	Xenopus tropicalis	88.78	0.00e+00	931.00
IUUC-Xma-133420	Xiphophorus maculatus	79.26	0.00e+00	866.00
IUUC-Yli-134362	Yarrowia lipolytica	59.45	6.00e-122	430.00
IUUC-Zma-135804	Zea mays	58.45	4.00e-125	441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence