iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016644

Ensembl Protein ID

Bra032557.1-P

UniProt Accession

M4EUS5; M4EUS5_BRARP

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit; WD repeat-containing protein 4 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra032557	Bra032557.1	Bra032557.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-16	59.1	925	967

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf......sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt+ vtc+af      +  +l sGs+D t+++WD+++g ll 
   Q: 925  GHTEFVTCIAFvsspelTQSYLMSGSGDSTVRLWDITSGSLLD 967
           8***********996642278*****************99875 PP

Organism

Brassica rapa

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MSMTIWALRR DVRRKSYSIL VRYISGSSSS GRSSVKPNEQ CIEKVLVANR GEIACRIMRT 60
AKRLGIQTVA VYSDADRDSL HVKSADEAVR IGPPPARLSY LSAAAIMEAA ARTGAQAIHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGATGA CGATATGGGC ACTTCGCCGT GACGTTCGCC GGAAAAGTTA CTCGATCCTC 60
GTCAGATACA TCTCCGGCTC TTCATCTTCT GGAAGATCTT CGGTCAAGCC TAATGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0092--Biotin
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR011761--ATP-grasp
IPR013815--ATP_grasp_subdomain_1
IPR013816--ATP_grasp_subdomain_2
IPR005481--BC-like_N
IPR001882--Biotin_BS
IPR011764--Biotin_carboxylation_dom
IPR005482--Biotin_COase_C
IPR000089--Biotin_lipoyl
IPR005479--CbamoylP_synth_lsu-like_ATP-bd
IPR016185--PreATP-grasp_dom
IPR011054--Rudment_hybrid_motif
IPR011053--Single_hybrid_motif
IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50975--ATP_GRASP
PS50979--BC
PS00188--BIOTIN
PS50968--BIOTINYL_LIPOYL
PS00866--CPSASE_1
PS00867--CPSASE_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02785--Biotin_carb_C
PF00289--Biotin_carb_N
PF00364--Biotin_lipoyl
PF02786--CPSase_L_D2
PF00400--WD40

SMART

SM00878--Biotin_carb_C
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004075--F:biotin carboxylase activity
GO:0046872--F:metal ion binding
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	50.12	2.00e-91	329.00
IUUC-Atr-002431	Amborella trichopoda	53.91	6.00e-35	139.00
IUUC-Apl-003975	Anas platyrhynchos	35.85	4.00e-24	105.00
IUUC-Aca-005170	Anolis carolinensis	35.12	6.00e-17	81.60
IUUC-Aly-005769	Arabidopsis lyrata	81.24	0.00e+00	642.00
IUUC-Ath-006733	Arabidopsis thaliana	80.54	0.00e+00	627.00
IUUC-Bta-012788	Bos taurus	39.56	8.00e-25	107.00
IUUC-Bdi-014458	Brachypodium distachyon	52.39	2.00e-101	362.00
IUUC-Bol-016398	Brassica oleracea	92.82	0.00e+00	724.00
IUUC-Cpo-021963	Cavia porcellus	37.91	2.00e-24	106.00
IUUC-Csa-024148	Chlorocebus sabaeus	35.20	3.00e-17	82.40
IUUC-Dre-028427	Danio rerio	33.61	1.00e-24	107.00
IUUC-Dor-030522	Dipodomys ordii	37.89	1.00e-24	107.00
IUUC-Dme-032136	Drosophila melanogaster	30.10	1.00e-13	70.90
IUUC-Fca-035833	Felis catus	38.46	4.00e-24	105.00
IUUC-Fal-037497	Ficedula albicollis	33.99	2.00e-24	105.00
IUUC-Gga-040547	Gallus gallus	35.71	7.00e-23	101.00
IUUC-Gac-041761	Gasterosteus aculeatus	36.22	1.00e-23	103.00
IUUC-Gma-043722	Glycine max	60.64	6.00e-136	476.00
IUUC-Ggo-045340	Gorilla gorilla	34.08	4.00e-16	78.60
IUUC-Hsa-046403	Homo sapiens	34.44	2.00e-17	83.20
IUUC-Hvu-047643	Hordeum vulgare	52.28	9.00e-105	373.00
IUUC-Itr-048103	Ictidomys tridecemlineatus	39.01	5.00e-25	108.00
IUUC-Lch-050682	Latimeria chalumnae	36.53	4.00e-28	118.00
IUUC-Lpe-050712	Leersia perrieri	51.54	3.00e-108	384.00
IUUC-Laf-054390	Loxodonta africana	41.21	5.00e-27	114.00
IUUC-Mcc-054747	Macaca mulatta	35.20	2.00e-17	83.20
IUUC-Mtr-058600	Medicago truncatula	61.20	1.00e-138	486.00
IUUC-Mga-059876	Meleagris gallopavo	35.20	2.00e-23	102.00
IUUC-Mmr-061518	Microcebus murinus	35.96	2.00e-22	99.80
IUUC-Mdo-063074	Monodelphis domestica	46.28	4.00e-165	575.00
IUUC-Nle-069914	Nomascus leucogenys	32.78	5.00e-14	71.60
IUUC-Oan-072951	Ornithorhynchus anatinus	37.36	2.00e-25	109.00
IUUC-Ocu-074679	Oryctolagus cuniculus	37.32	8.00e-17	80.90
IUUC-Oba-075355	Oryza barthii	46.93	1.00e-98	353.00
IUUC-Obr-076769	Oryza brachyantha	53.44	9.00e-119	419.00
IUUC-Ogl-077168	Oryza glaberrima	51.55	6.00e-115	407.00
IUUC-Ogu-078275	Oryza glumaepatula	46.70	2.00e-97	349.00
IUUC-Oin-079207	Oryza indica	51.55	6.00e-115	407.00
IUUC-Ome-081169	Oryza meridionalis	34.61	6.00e-54	204.00
IUUC-Oni-082437	Oryza nivara	46.70	5.00e-98	351.00
IUUC-Opu-084031	Oryza punctata	51.55	7.00e-113	400.00
IUUC-Oru-084380	Oryza rufipogon	46.70	7.00e-98	350.00
IUUC-Osa-085327	Oryza sativa	51.31	4.00e-114	404.00
IUUC-Ola-086716	Oryzias latipes	33.85	4.00e-26	111.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.41	4.00e-38	151.00
IUUC-Oar-090239	Ovis aries	39.56	7.00e-25	107.00
IUUC-Ptr-090851	Pan troglodytes	33.89	4.00e-16	79.00
IUUC-Pan-092558	Papio anubis	35.20	2.00e-17	82.80
IUUC-Ppa-095757	Physcomitrella patens	41.96	3.00e-79	288.00
IUUC-Pfo-096465	Poecilia formosa	33.64	1.00e-22	100.00
IUUC-Pab-097722	Pongo abelii	30.81	1.00e-16	80.50
IUUC-Pop-098979	Populus trichocarpa	59.45	2.00e-141	494.00
IUUC-Pca-100753	Procavia capensis	50.00	1.00e-16	80.90
IUUC-Ppe-101515	Prunus persica	62.88	2.00e-145	508.00
IUUC-Sit-110020	Setaria italica	52.76	5.00e-115	407.00
IUUC-Sly-111543	Solanum lycopersicum	57.78	1.00e-134	473.00
IUUC-Stu-111925	Solanum tuberosum	57.78	8.00e-136	476.00
IUUC-Sbi-114061	Sorghum bicolor	50.57	4.00e-115	407.00
IUUC-Tgu-117321	Taeniopygia guttata	33.50	7.00e-20	90.90
IUUC-Tru-118454	Takifugu rubripes	35.65	3.00e-27	115.00
IUUC-Tni-119894	Tetraodon nigroviridis	34.11	8.00e-25	107.00
IUUC-Tca-121746	Theobroma cacao	61.57	2.00e-145	508.00
IUUC-Tae-124459	Triticum aestivum	53.72	2.00e-108	385.00
IUUC-Tur-126254	Triticum urartu	50.00	6.00e-85	307.00
IUUC-Tbe-127683	Tupaia belangeri	50.00	3.00e-16	79.30
IUUC-Ttr-129056	Tursiops truncatus	40.66	6.00e-25	108.00
IUUC-Vvi-131428	Vitis vinifera	60.60	2.00e-146	511.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence