iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mvi-060221

Ensembl Protein ID

MVLG_01605T0

UniProt Accession

U5H2M1; U5H2M1_USTV1

Genbank Protein ID

KDE08124.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

AEIJ01000157

Gene Name

MVLG_01605

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MVLG_01605	MVLG_01605T0	MVLG_01605T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.50e-72	242.5	44	563

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesi 97
           YDRQ+rlw   +q +l++a +l+v+a+++++ +lKnLvl G+g++t++D  +v+ s ++++F++++ + gk+KAe + ++l e+n dv++ea  +++
   Q: 44   YDRQLRLWAKSGQSALENADILVVNATATAAQTLKNLVLPGIGKFTLLDPTKVQGSSIGNNFFLDPTSLGKNKAEQVTQFLLEMNNDVKGEAIVQDL 140
           ************************************************************************************************* PP
   S: 98   teleeeiv.FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpn.........a 182
           +    + +  ++k++++++ + n    +++ +l +++++pli +++ G++G +++ i +l++ + +++   ++++  Pf++l+e+ n         a
   Q: 141  SSVLSTSPeALEKYSLIIAVDVNPTDLLQLSDLAWKYHIPLIKVRSCGFYGSLTTQINELPIVETHPEslIDLRVHHPFPELIEYANtfnydrmdsA 237
           ******99*****************************************************************************888889999999 PP
   S: 183  aehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv.... 274
           +  +++ +v++ k l+e+++++e++ +++++e +++ d v ++ ++ d enf+ea+++ ++a  kt i+s ++ l+++++c+ v+ s+++fw+    
   Q: 238  EFGHVPAVVILVKALQEWRESHEGKGPSTTTERKQFADSVLAKKRQHDDENFDEAVTLFRRAGTKTGIPSeVQALFDDPSCEDVSASSANFWLllha 334
           99****9****************************************************************************************** PP
   S: 275  ................................................................................................s 275
                                                                                                           s
   Q: 335  vrlftlhasnpsgllplsgalpdmkahssvyvglqnvyrtqaqqdlklttsllfqllqslgldcsrieveeietfvkhsaylkvvrgrslrmeiedS 431
           *************************************************************************888888888888888888888877 PP
   S: 276  fcsnaealqvpekvekdeevvkasaplylllralerfekkkgrkpgelsfekddds....avdlvtaaanlraeslgiep.kldddlikeiagniip 367
           + s + +l++   + k   v +++ ++yl lr +e f +++gr+pg+ + +++       +v +v+++       l+ e+ +  ++   e+++ +++
   Q: 432  LLSEEGKLKEAIEASKWDVVPTRAVEIYLTLRGAEVFYERRGREPGTGEGDEEGTAdredLVGIVKEVVEGLGGGLDEEAwEEIEKTCWEVCRAGAS 528
           77777777777777777777777777*******************9888776533333469999**999888888888888778888899******* PP
   S: 368  aiattnavvgGlaaqEviKvvsgkfeplknfflfd 402
            +  ++a +gG++aqE+iK+v++++ pl+ + + +
   Q: 529  DLPQIAALLGGMVAQEAIKIVTKQYGPLNGTCVLN 563
           ****************************9877665 PP

Organism

Microbotryum violaceum

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MAAQDVLPPP VQDSVDISHT PLIPSTSAST STSSARPDAH TQRYDRQLRL WAKSGQSALE 60
NADILVVNAT ATAAQTLKNL VLPGIGKFTL LDPTKVQGSS IGNNFFLDPT SLGKNKAEQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCGTCGG GCTTCGGTCG CGCTCCTAAT AGAAAGAACG TAACCTAATC CGGCTGCATC 60
TGACATCGCG CTGCAATAGC AACCTCACCC CGCGACCGCC TCTTACCTCC TGCCGCTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	34.96	6.00e-82	296.00
IUUC-Aml-002333	Ailuropoda melanoleuca	37.38	1.00e-96	345.00
IUUC-Atr-002644	Amborella trichopoda	33.84	7.00e-79	286.00
IUUC-Apl-003446	Anas platyrhynchos	35.45	2.00e-85	307.00
IUUC-Aca-004450	Anolis carolinensis	36.45	5.00e-94	336.00
IUUC-Aly-006187	Arabidopsis lyrata	33.08	9.00e-83	299.00
IUUC-Ath-006692	Arabidopsis thaliana	33.64	2.00e-86	311.00
IUUC-Acl-008333	Aspergillus clavatus	33.45	6.00e-79	286.00
IUUC-Afl-008529	Aspergillus flavus	35.37	2.00e-86	311.00
IUUC-Afu-009071	Aspergillus fumigatus	35.38	8.00e-83	299.00
IUUC-Ani-009443	Aspergillus nidulans	35.29	2.00e-79	288.00
IUUC-Ang-009669	Aspergillus niger	34.28	3.00e-84	304.00
IUUC-Aor-009914	Aspergillus oryzae	35.04	2.00e-84	304.00
IUUC-Ate-010450	Aspergillus terreus	35.29	3.00e-87	313.00
IUUC-Ame-011183	Astyanax mexicanus	34.14	1.00e-92	332.00
IUUC-Bgr-012111	Blumeria graminis	32.97	2.00e-69	254.00
IUUC-Bta-012583	Bos taurus	36.78	1.00e-96	345.00
IUUC-Bci-013892	Botrytis cinerea	35.55	3.00e-76	277.00
IUUC-Bdi-014592	Brachypodium distachyon	33.78	8.00e-79	286.00
IUUC-Bol-015487	Brassica oleracea	33.90	4.00e-86	310.00
IUUC-Bra-017506	Brassica rapa	33.21	1.00e-85	308.00
IUUC-Cel-018456	Caenorhabditis elegans	30.32	5.00e-65	240.00
IUUC-Cja-020007	Callithrix jacchus	36.58	3.00e-94	337.00
IUUC-Cfa-020324	Canis familiaris	37.34	3.00e-98	350.00
IUUC-Cpo-022248	Cavia porcellus	32.84	7.00e-53	199.00
IUUC-Csa-023149	Chlorocebus sabaeus	33.20	9.00e-69	252.00
IUUC-Cho-024537	Choloepus hoffmanni	30.13	1.00e-55	209.00
IUUC-Cin-025763	Ciona intestinalis	37.99	1.00e-102	365.00
IUUC-Csv-026113	Ciona savignyi	36.41	3.00e-101	360.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	31.78	6.00e-68	249.00
IUUC-Cne-026884	Cryptococcus neoformans	38.03	4.00e-91	327.00
IUUC-Cme-027210	Cyanidioschyzon merolae	28.08	7.00e-24	103.00
IUUC-Dre-028140	Danio rerio	34.14	3.00e-92	330.00
IUUC-Dno-030033	Dasypus novemcinctus	38.15	2.00e-85	308.00
IUUC-Dor-030513	Dipodomys ordii	55.10	2.00e-28	118.00
IUUC-Dse-031536	Dothistroma septosporum	33.89	3.00e-88	317.00
IUUC-Dme-031683	Drosophila melanogaster	33.46	4.00e-76	276.00
IUUC-Ete-032420	Echinops telfairi	35.91	5.00e-66	243.00
IUUC-Eca-033992	Equus caballus	33.41	4.00e-66	243.00
IUUC-Eeu-034713	Erinaceus europaeus	55.79	6.00e-29	120.00
IUUC-Fca-036548	Felis catus	37.15	7.00e-96	342.00
IUUC-Fal-037600	Ficedula albicollis	34.89	7.00e-85	306.00
IUUC-Fox-038037	Fusarium oxysporum	34.95	1.00e-84	305.00
IUUC-Fso-038387	Fusarium solani	34.22	1.00e-82	299.00
IUUC-Gmo-038562	Gadus morhua	33.70	8.00e-91	325.00
IUUC-Ggr-040005	Gaeumannomyces graminis	34.00	3.00e-78	284.00
IUUC-Gga-041129	Gallus gallus	36.38	5.00e-91	326.00
IUUC-Gac-042558	Gasterosteus aculeatus	35.73	5.00e-92	330.00
IUUC-Gma-043610	Glycine max	34.35	6.00e-82	296.00
IUUC-Ggo-045611	Gorilla gorilla	36.58	5.00e-94	336.00
IUUC-Hsa-046563	Homo sapiens	36.78	9.00e-96	342.00
IUUC-Hvu-047790	Hordeum vulgare	33.16	9.00e-49	185.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	36.97	3.00e-96	343.00
IUUC-Kpa-049309	Komagataella pastoris	34.46	5.00e-78	283.00
IUUC-Lch-050038	Latimeria chalumnae	35.61	1.00e-87	315.00
IUUC-Lpe-051535	Leersia perrieri	30.51	4.00e-60	224.00
IUUC-Loc-051917	Lepisosteus oculatus	32.67	3.00e-79	287.00
IUUC-Lma-053112	Leptosphaeria maculans	35.59	1.00e-89	322.00
IUUC-Laf-053690	Loxodonta africana	37.15	1.00e-96	345.00
IUUC-Mcc-055117	Macaca mulatta	35.78	3.00e-91	327.00
IUUC-Meu-056761	Macropus eugenii	29.47	6.00e-58	216.00
IUUC-Mor-057230	Magnaporthe oryzae	37.14	2.00e-83	301.00
IUUC-Mpo-057514	Magnaporthe poae	34.96	2.00e-74	271.00
IUUC-Mtr-058551	Medicago truncatula	34.58	2.00e-77	281.00
IUUC-Mla-059183	Melampsora laricipopulina	43.39	3.00e-123	433.00
IUUC-Mga-060144	Meleagris gallopavo	35.73	4.00e-88	317.00
IUUC-Mmr-061325	Microcebus murinus	36.03	2.00e-93	334.00
IUUC-Mdo-062532	Monodelphis domestica	35.67	1.00e-91	328.00
IUUC-Mmu-063956	Mus musculus	36.60	2.00e-95	341.00
IUUC-Mac-064521	Musa acuminata	33.77	2.00e-83	301.00
IUUC-Mpu-066716	Mustela putorius furo	36.96	1.00e-88	318.00
IUUC-Mlu-067459	Myotis lucifugus	36.88	2.00e-96	344.00
IUUC-Nfi-068245	Neosartorya fischeri	35.26	1.00e-81	295.00
IUUC-Ncr-068910	Neurospora crassa	34.10	1.00e-78	285.00
IUUC-Nle-070034	Nomascus leucogenys	35.02	3.00e-87	313.00
IUUC-Opr-070552	Ochotona princeps	33.20	6.00e-67	246.00
IUUC-Ont-071426	Oreochromis niloticus	33.77	1.00e-91	328.00
IUUC-Oan-073389	Ornithorhynchus anatinus	33.26	7.00e-57	213.00
IUUC-Ocu-074911	Oryctolagus cuniculus	37.15	1.00e-96	345.00
IUUC-Oba-075437	Oryza barthii	32.96	3.00e-71	261.00
IUUC-Obr-076684	Oryza brachyantha	32.84	1.00e-63	236.00
IUUC-Ogl-077170	Oryza glaberrima	32.96	3.00e-71	261.00
IUUC-Ogu-078844	Oryza glumaepatula	31.78	2.00e-63	234.00
IUUC-Oin-079105	Oryza indica	32.96	3.00e-71	261.00
IUUC-Olo-080943	Oryza longistaminata	29.47	9.00e-57	212.00
IUUC-Oni-082891	Oryza nivara	30.34	5.00e-64	236.00
IUUC-Opu-083457	Oryza punctata	32.58	6.00e-70	256.00
IUUC-Oru-084960	Oryza rufipogon	29.47	7.00e-57	213.00
IUUC-Osa-085358	Oryza sativa	32.96	5.00e-71	259.00
IUUC-Ola-086420	Oryzias latipes	31.69	1.00e-51	194.00
IUUC-Olu-087625	Ostreococcus lucimarinus	28.62	5.00e-45	174.00
IUUC-Oga-088810	Otolemur garnettii	37.34	2.00e-98	350.00
IUUC-Oar-089196	Ovis aries	36.58	8.00e-95	339.00
IUUC-Ptr-090617	Pan troglodytes	36.60	5.00e-95	339.00
IUUC-Pan-092761	Papio anubis	36.97	4.00e-96	343.00
IUUC-Psi-093191	Pelodiscus sinensis	34.83	5.00e-86	310.00
IUUC-Pma-094380	Petromyzon marinus	37.67	4.00e-87	313.00
IUUC-Pno-095084	Phaeosphaeria nodorum	34.42	9.00e-76	277.00
IUUC-Ppa-095798	Physcomitrella patens	32.90	2.00e-81	295.00
IUUC-Pfo-096467	Poecilia formosa	34.20	1.00e-90	325.00
IUUC-Pab-098255	Pongo abelii	38.15	3.00e-85	307.00
IUUC-Pop-099871	Populus trichocarpa	33.21	7.00e-84	303.00
IUUC-Pca-100807	Procavia capensis	41.05	1.00e-42	165.00
IUUC-Ppe-101280	Prunus persica	34.35	2.00e-85	307.00
IUUC-Pva-102333	Pteropus vampyrus	34.93	5.00e-86	310.00
IUUC-Pgr-103401	Puccinia graminis	35.94	6.00e-101	359.00
IUUC-Ptt-103889	Puccinia triticina	29.57	3.00e-75	274.00
IUUC-Pte-104355	Pyrenophora teres	35.29	1.00e-87	315.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	34.94	6.00e-87	313.00
IUUC-Rno-105810	Rattus norvegicus	36.04	4.00e-94	337.00
IUUC-Sce-106397	Saccharomyces cerevisiae	27.86	3.00e-26	111.00
IUUC-Sha-106770	Sarcophilus harrisii	39.11	2.00e-57	213.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	29.89	1.00e-70	258.00
IUUC-Spo-108276	Schizosaccharomyces pombe	28.41	7.00e-63	233.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	35.44	5.00e-78	283.00
IUUC-Smo-109296	Selaginella moellendorffii	35.37	3.00e-84	304.00
IUUC-Sit-110157	Setaria italica	34.60	4.00e-89	320.00
IUUC-Sly-111105	Solanum lycopersicum	34.08	2.00e-84	305.00
IUUC-Stu-112469	Solanum tuberosum	33.58	8.00e-85	305.00
IUUC-Sar-113083	Sorex araneus	42.00	3.00e-34	137.00
IUUC-Sbi-113813	Sorghum bicolor	34.92	4.00e-87	313.00
IUUC-Sre-115058	Sporisorium reilianum	38.66	2.00e-110	391.00
IUUC-Tgu-116772	Taeniopygia guttata	35.06	3.00e-87	313.00
IUUC-Tru-118686	Takifugu rubripes	35.12	6.00e-93	333.00
IUUC-Tsy-119111	Tarsius syrichta	35.74	2.00e-46	178.00
IUUC-Tni-120231	Tetraodon nigroviridis	31.18	2.00e-76	277.00
IUUC-Tca-121491	Theobroma cacao	33.08	7.00e-77	279.00
IUUC-Tre-122103	Trichoderma reesei	33.15	2.00e-77	281.00
IUUC-Tvi-122672	Trichoderma virens	34.26	7.00e-80	289.00
IUUC-Tae-125455	Triticum aestivum	34.29	2.00e-81	295.00
IUUC-Tur-126487	Triticum urartu	34.16	7.00e-78	283.00
IUUC-Tme-127097	Tuber melanosporum	36.33	2.00e-87	314.00
IUUC-Ttr-128465	Tursiops truncatus	35.11	1.00e-87	315.00
IUUC-Uma-129645	Ustilago maydis	38.88	9.00e-113	399.00
IUUC-Vda-129989	Verticillium dahliae	30.70	2.00e-62	231.00
IUUC-Vpa-130529	Vicugna pacos	35.29	1.00e-88	318.00
IUUC-Vvi-131059	Vitis vinifera	34.03	3.00e-79	287.00
IUUC-Xtr-132002	Xenopus tropicalis	36.10	9.00e-92	329.00
IUUC-Xma-133930	Xiphophorus maculatus	34.63	4.00e-90	323.00
IUUC-Yli-134505	Yarrowia lipolytica	33.52	1.00e-81	295.00
IUUC-Zma-135895	Zea mays	34.54	3.00e-86	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence