iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036421

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AANG02161252

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000027839.1	ENSFCAT00000028106.1	ENSFCAP00000016969.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	8.60e-73	245.6	3	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           +++wl+Le++P++ +++++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d++++++f+kq
   Q: 3    GQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVTSSVYFMKQ 89
           589*************************************************************766..5589**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +i+N+C+t++l+++++n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf+
   Q: 90   TISNACGTIGLIHAIANNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSID-------EKVDLHFI 171
           ***********************************************************************888.......8899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           ++v+++g+lyeldg+kpfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 172  ALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 230
           ********************************************....***********9875 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MEGQRWLPLE ANPEVTNQFL KQLGLHPNWQ FVDVYGMDPE LLSMVPRPVC AVLLLFPITE 60
KYEVFRTEEE EKIKSQGQDV TSSVYFMKQT ISNACGTIGL IHAIANNKDK MHFESGSTLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGATTCAG ATTCTTTTTC CTTTTTCAGT ACGGAGATGG CTTATCTTGT CTTCTCCGAT 60
TGTATCTTAA TTTAAAATGT AAGACTTGAG TGTGGCTCTG CAGGGAACGA GAAAAGCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fca:101083135

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	44.07	2.00e-53	202.00
IUUC-Aml-001344	Ailuropoda melanoleuca	100.00	2.00e-137	481.00
IUUC-Atr-002931	Amborella trichopoda	47.49	2.00e-48	184.00
IUUC-Apl-003949	Anas platyrhynchos	87.32	8.00e-105	372.00
IUUC-Aca-004924	Anolis carolinensis	82.68	3.00e-115	407.00
IUUC-Aly-005721	Arabidopsis lyrata	50.22	3.00e-60	224.00
IUUC-Ath-006827	Arabidopsis thaliana	50.88	1.00e-60	225.00
IUUC-Ago-007950	Ashbya gossypii	35.14	2.00e-27	115.00
IUUC-Acl-008305	Aspergillus clavatus	39.56	2.00e-40	158.00
IUUC-Afl-008611	Aspergillus flavus	40.25	1.00e-43	169.00
IUUC-Afu-008945	Aspergillus fumigatus	40.68	2.00e-43	169.00
IUUC-Ani-009339	Aspergillus nidulans	40.51	4.00e-44	171.00
IUUC-Ang-009691	Aspergillus niger	38.72	3.00e-43	168.00
IUUC-Aor-009961	Aspergillus oryzae	40.25	1.00e-43	169.00
IUUC-Ate-010316	Aspergillus terreus	40.85	2.00e-44	172.00
IUUC-Ame-011157	Astyanax mexicanus	73.04	1.00e-101	362.00
IUUC-Bgr-012125	Blumeria graminis	36.71	8.00e-40	156.00
IUUC-Bta-012673	Bos taurus	99.13	2.00e-136	478.00
IUUC-Bci-013734	Botrytis cinerea	37.61	2.00e-42	165.00
IUUC-Bdi-014330	Brachypodium distachyon	45.81	2.00e-56	212.00
IUUC-Bol-015214	Brassica oleracea	52.86	1.00e-63	235.00
IUUC-Bra-017491	Brassica rapa	53.30	3.00e-63	234.00
IUUC-Cel-018302	Caenorhabditis elegans	40.09	1.00e-35	142.00
IUUC-Cja-019642	Callithrix jacchus	54.71	2.00e-63	235.00
IUUC-Cfa-020371	Canis familiaris	97.37	2.00e-107	381.00
IUUC-Cpo-022036	Cavia porcellus	96.52	2.00e-131	461.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	44.19	3.00e-38	151.00
IUUC-Csa-023854	Chlorocebus sabaeus	99.13	1.00e-135	475.00
IUUC-Cho-024548	Choloepus hoffmanni	56.38	8.00e-20	89.70
IUUC-Cin-025545	Ciona intestinalis	49.78	6.00e-67	246.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	34.47	2.00e-32	132.00
IUUC-Cne-026914	Cryptococcus neoformans	35.19	2.00e-30	125.00
IUUC-Cme-027216	Cyanidioschyzon merolae	37.39	3.00e-28	118.00
IUUC-Dre-028356	Danio rerio	74.35	2.00e-103	367.00
IUUC-Dno-029325	Dasypus novemcinctus	54.26	7.00e-64	236.00
IUUC-Dor-030114	Dipodomys ordii	53.81	1.00e-71	261.00
IUUC-Dse-031461	Dothistroma septosporum	40.51	4.00e-39	154.00
IUUC-Dme-032146	Drosophila melanogaster	50.67	3.00e-62	231.00
IUUC-Ete-033092	Echinops telfairi	55.03	2.00e-53	201.00
IUUC-Eca-033220	Equus caballus	99.57	2.00e-136	477.00
IUUC-Eeu-034493	Erinaceus europaeus	52.47	8.00e-61	226.00
IUUC-Fal-036773	Ficedula albicollis	87.10	1.00e-106	378.00
IUUC-Fox-037830	Fusarium oxysporum	36.80	3.00e-41	161.00
IUUC-Fso-038259	Fusarium solani	36.68	2.00e-39	157.00
IUUC-Gmo-039468	Gadus morhua	68.70	3.00e-84	304.00
IUUC-Ggr-039832	Gaeumannomyces graminis	37.12	1.00e-37	149.00
IUUC-Gga-041205	Gallus gallus	85.65	6.00e-112	396.00
IUUC-Gac-041629	Gasterosteus aculeatus	68.42	6.00e-88	316.00
IUUC-Gma-043057	Glycine max	49.78	8.00e-54	203.00
IUUC-Ggo-044533	Gorilla gorilla	99.57	4.00e-136	476.00
IUUC-Hsa-046754	Homo sapiens	100.00	2.00e-137	481.00
IUUC-Hvu-047176	Hordeum vulgare	41.05	6.00e-44	170.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	97.47	7.00e-91	325.00
IUUC-Kpa-049123	Komagataella pastoris	37.09	6.00e-33	133.00
IUUC-Lch-049685	Latimeria chalumnae	78.51	5.00e-110	389.00
IUUC-Lpe-051377	Leersia perrieri	45.32	3.00e-47	181.00
IUUC-Loc-051988	Lepisosteus oculatus	76.52	5.00e-106	376.00
IUUC-Lma-053316	Leptosphaeria maculans	40.26	1.00e-42	166.00
IUUC-Laf-053985	Loxodonta africana	98.27	1.00e-134	471.00
IUUC-Mcc-055888	Macaca mulatta	97.83	1.00e-132	464.00
IUUC-Meu-056478	Macropus eugenii	52.91	1.00e-71	262.00
IUUC-Mor-057271	Magnaporthe oryzae	37.12	2.00e-41	162.00
IUUC-Mpo-057343	Magnaporthe poae	32.19	2.00e-22	98.20
IUUC-Mtr-057713	Medicago truncatula	48.67	8.00e-54	202.00
IUUC-Mla-058942	Melampsora laricipopulina	45.37	2.00e-47	182.00
IUUC-Mga-059702	Meleagris gallopavo	86.85	2.00e-104	370.00
IUUC-Mvi-060249	Microbotryum violaceum	44.30	4.00e-42	164.00
IUUC-Mmr-061284	Microcebus murinus	100.00	2.00e-92	331.00
IUUC-Mdo-062639	Monodelphis domestica	79.85	8.00e-123	432.00
IUUC-Mmu-063299	Mus musculus	98.26	1.00e-135	474.00
IUUC-Mac-065075	Musa acuminata	45.85	4.00e-54	204.00
IUUC-Mpu-066769	Mustela putorius furo	100.00	2.00e-137	481.00
IUUC-Mlu-066937	Myotis lucifugus	96.96	9.00e-133	465.00
IUUC-Nfi-068320	Neosartorya fischeri	40.76	2.00e-44	172.00
IUUC-Ncr-068673	Neurospora crassa	38.96	1.00e-45	176.00
IUUC-Nle-069175	Nomascus leucogenys	100.00	2.00e-124	437.00
IUUC-Opr-070652	Ochotona princeps	100.00	3.00e-64	238.00
IUUC-Ont-072170	Oreochromis niloticus	70.61	2.00e-89	321.00
IUUC-Oan-073247	Ornithorhynchus anatinus	93.81	2.00e-59	220.00
IUUC-Ocu-074422	Oryctolagus cuniculus	98.26	7.00e-136	475.00
IUUC-Oba-075098	Oryza barthii	42.04	2.00e-50	191.00
IUUC-Obr-076041	Oryza brachyantha	45.18	6.00e-55	206.00
IUUC-Ogl-076980	Oryza glaberrima	45.61	9.00e-55	206.00
IUUC-Ogu-078978	Oryza glumaepatula	38.74	8.00e-48	183.00
IUUC-Oin-079285	Oryza indica	41.59	1.00e-49	189.00
IUUC-Olo-080671	Oryza longistaminata	42.04	9.00e-50	189.00
IUUC-Ome-081428	Oryza meridionalis	41.15	2.00e-48	185.00
IUUC-Oni-082406	Oryza nivara	42.04	2.00e-50	191.00
IUUC-Opu-083305	Oryza punctata	42.04	8.00e-49	186.00
IUUC-Oru-084969	Oryza rufipogon	42.04	2.00e-50	191.00
IUUC-Osa-085830	Oryza sativa	45.61	9.00e-55	206.00
IUUC-Ola-086893	Oryzias latipes	68.42	9.00e-86	309.00
IUUC-Olu-087858	Ostreococcus lucimarinus	44.93	9.00e-53	199.00
IUUC-Oga-088055	Otolemur garnettii	99.57	4.00e-136	476.00
IUUC-Oar-090319	Ovis aries	98.70	5.00e-136	476.00
IUUC-Ptr-091536	Pan troglodytes	55.16	2.00e-64	238.00
IUUC-Pan-092714	Papio anubis	98.70	8.00e-135	472.00
IUUC-Psi-094036	Pelodiscus sinensis	86.64	3.00e-106	377.00
IUUC-Pma-094412	Petromyzon marinus	64.94	3.00e-55	206.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.22	7.00e-35	140.00
IUUC-Ppa-095519	Physcomitrella patens	51.11	2.00e-64	238.00
IUUC-Pfo-096182	Poecilia formosa	67.83	2.00e-88	318.00
IUUC-Pab-098216	Pongo abelii	100.00	3.00e-83	299.00
IUUC-Pop-099282	Populus trichocarpa	49.12	7.00e-54	203.00
IUUC-Pca-100818	Procavia capensis	43.88	5.00e-35	140.00
IUUC-Ppe-101332	Prunus persica	48.23	5.00e-56	210.00
IUUC-Pva-102954	Pteropus vampyrus	53.81	5.00e-61	226.00
IUUC-Pgr-103430	Puccinia graminis	47.48	6.00e-51	193.00
IUUC-Ptt-103955	Puccinia triticina	49.14	2.00e-51	195.00
IUUC-Pte-104414	Pyrenophora teres	38.89	1.00e-39	156.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	34.03	6.00e-35	140.00
IUUC-Rno-105096	Rattus norvegicus	97.39	1.00e-134	471.00
IUUC-Sce-106412	Saccharomyces cerevisiae	36.08	3.00e-28	118.00
IUUC-Sha-106677	Sarcophilus harrisii	94.01	1.00e-121	428.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.95	2.00e-26	111.00
IUUC-Spo-108322	Schizosaccharomyces pombe	31.00	3.00e-26	111.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	37.61	9.00e-39	153.00
IUUC-Smo-108914	Selaginella moellendorffii	49.14	3.00e-54	204.00
IUUC-Sit-110163	Setaria italica	47.41	1.00e-55	209.00
IUUC-Sly-111613	Solanum lycopersicum	49.78	2.00e-62	231.00
IUUC-Stu-112526	Solanum tuberosum	50.88	6.00e-58	216.00
IUUC-Sar-113190	Sorex araneus	39.13	1.00e-15	74.70
IUUC-Sbi-114545	Sorghum bicolor	46.72	2.00e-53	202.00
IUUC-Sre-114961	Sporisorium reilianum	42.49	1.00e-40	159.00
IUUC-Ssc-115255	Sus scrofa	97.64	6.00e-123	432.00
IUUC-Tgu-117003	Taeniopygia guttata	86.09	3.00e-111	394.00
IUUC-Tru-118330	Takifugu rubripes	62.84	7.00e-69	254.00
IUUC-Tsy-119488	Tarsius syrichta	98.25	2.00e-63	234.00
IUUC-Tni-120042	Tetraodon nigroviridis	64.13	8.00e-71	261.00
IUUC-Tca-120976	Theobroma cacao	47.79	4.00e-56	211.00
IUUC-Tre-122149	Trichoderma reesei	38.70	1.00e-43	169.00
IUUC-Tvi-122450	Trichoderma virens	38.70	2.00e-43	168.00
IUUC-Tae-122693	Triticum aestivum	45.22	6.00e-54	204.00
IUUC-Tur-126250	Triticum urartu	44.07	4.00e-53	201.00
IUUC-Tme-126961	Tuber melanosporum	37.02	3.00e-36	144.00
IUUC-Tbe-128048	Tupaia belangeri	56.21	3.00e-54	204.00
IUUC-Ttr-128494	Tursiops truncatus	53.36	2.00e-61	228.00
IUUC-Uma-129382	Ustilago maydis	41.38	3.00e-43	168.00
IUUC-Vda-129678	Verticillium dahliae	32.07	5.00e-32	130.00
IUUC-Vpa-130783	Vicugna pacos	99.13	1.00e-63	236.00
IUUC-Vvi-131661	Vitis vinifera	48.03	2.00e-57	214.00
IUUC-Xtr-132428	Xenopus tropicalis	74.35	7.00e-107	379.00
IUUC-Xma-134245	Xiphophorus maculatus	67.11	3.00e-88	317.00
IUUC-Yli-134570	Yarrowia lipolytica	35.90	1.00e-36	146.00
IUUC-Zma-134740	Zea mays	45.85	3.00e-55	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence