iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062099

Ensembl Protein ID

ENSMODP00000025387.2

UniProt Accession

F7BFU4; F7BFU4_MONDO

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020296.2	ENSMODT00000025838.2	ENSMODP00000025387.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.60e-12	46.2	2	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +lydye+ ++++L++kk +  ++i  ++++++W+++ + ++gk G +P+n+v+ ++
   Q: 2    MALYDYESRTTEDLSFKKSERFQII--NNKEGDWWEARSIATGKTGYIPSNYVAPAN 56
           58***********************..8999**********************9876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

FMALYDYESR TTEDLSFKKS ERFQIINNKE GDWWEARSIA TGKTGYIPSN YVAPANSIQA 60
EEWYFGKMGR KDAERASSEG REALRGIFLV RESETTKGTF SLSLRDWDEL RGDNVKHYKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCATGGCCT TATATGATTA TGAAAGTAGA ACTACAGAAG ATCTTTCTTT TAAGAAGAGT 60
GAAAGATTTC AAATAATTAA TAATAAGGAA GGAGATTGGT GGGAAGCAAG ATCCATAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Oba-075994	Oryza barthii	34.30	3.00e-23	103.00
IUUC-Ppe-102072	Prunus persica	37.88	5.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence