iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000000968.8	ENSRNOT00000092401.1	ENSRNOP00000075825.1
ENSRNOG00000000968.8	ENSRNOT00000001282.7	ENSRNOP00000001282.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-06	28.3	614	655

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C +d+   + ++ lpC H fh +C+ +w       s + +CP+Cr
   Q: 614  CSVCISDYvaGNKLRQLPCLHEFHIHCIDRW------LSENCTCPVCR 655
           9*******884449*****************......**********8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MNPSRSRSGG SGEEISFQEN ERRWQQERLH REEAYYQFIN ALNDEDYRLM RDHNLLGTPG 60
DITSEELQQR LDRAKEQLVS QPGSGSGTSD GDSENLRENS DEGSLLRWLS TFRRTGNVTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACGCACCG ACAGGGTCGG CGCAGACAGT GGCGTGCCTT AGTTCTTCTA GATGGTGAAA 60
GAAGGCCTGA GACCGGACGG TCTTCTCTCA GCTTTCTCTC TGCTCGGTCG ACTCCGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0030424--C:axon
GO:0005737--C:cytoplasm
GO:0031965--C:nuclear membrane
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030517--P:negative regulation of axon extension
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044314--P:protein K27-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0060765--P:regulation of androgen receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000525	Aegilops tauschii	55.56	6.00e-11	58.90
IUUC-Aml-001415	Ailuropoda melanoleuca	72.53	0.00e+00	796.00
IUUC-Apl-003834	Anas platyrhynchos	53.72	3.00e-152	531.00
IUUC-Aca-004373	Anolis carolinensis	45.81	2.00e-119	422.00
IUUC-Ame-011730	Astyanax mexicanus	60.42	5.00e-79	288.00
IUUC-Bta-012763	Bos taurus	65.10	0.00e+00	696.00
IUUC-Bol-015504	Brassica oleracea	42.31	1.00e-15	76.60
IUUC-Bra-017535	Brassica rapa	42.11	7.00e-16	77.00
IUUC-Cja-018980	Callithrix jacchus	72.61	0.00e+00	825.00
IUUC-Cfa-020416	Canis familiaris	72.42	0.00e+00	808.00
IUUC-Cpo-022086	Cavia porcellus	69.23	3.00e-133	468.00
IUUC-Csa-023246	Chlorocebus sabaeus	71.39	0.00e+00	828.00
IUUC-Cho-024749	Choloepus hoffmanni	68.12	0.00e+00	655.00
IUUC-Cme-027313	Cyanidioschyzon merolae	50.98	2.00e-12	67.00
IUUC-Dre-028428	Danio rerio	59.52	5.00e-75	275.00
IUUC-Dno-029617	Dasypus novemcinctus	69.43	0.00e+00	785.00
IUUC-Dor-030800	Dipodomys ordii	67.27	4.00e-103	369.00
IUUC-Ete-032882	Echinops telfairi	68.85	2.00e-130	459.00
IUUC-Eca-033892	Equus caballus	72.41	0.00e+00	865.00
IUUC-Eeu-034563	Erinaceus europaeus	70.45	6.00e-88	318.00
IUUC-Fca-035765	Felis catus	72.08	0.00e+00	789.00
IUUC-Fal-036981	Ficedula albicollis	52.81	3.00e-149	522.00
IUUC-Gmo-039344	Gadus morhua	59.04	2.00e-87	317.00
IUUC-Gga-041114	Gallus gallus	59.10	1.00e-98	353.00
IUUC-Gac-042220	Gasterosteus aculeatus	59.58	1.00e-87	317.00
IUUC-Ggo-044902	Gorilla gorilla	71.18	0.00e+00	842.00
IUUC-Hsa-046548	Homo sapiens	71.32	0.00e+00	845.00
IUUC-Hvu-047246	Hordeum vulgare	42.31	2.00e-14	72.40
IUUC-Itr-048447	Ictidomys tridecemlineatus	71.68	0.00e+00	842.00
IUUC-Lch-050541	Latimeria chalumnae	53.11	9.00e-93	334.00
IUUC-Lpe-050856	Leersia perrieri	45.95	2.00e-14	72.40
IUUC-Laf-054296	Loxodonta africana	66.03	0.00e+00	739.00
IUUC-Mcc-054858	Macaca mulatta	70.70	0.00e+00	836.00
IUUC-Meu-056296	Macropus eugenii	59.10	1.00e-113	403.00
IUUC-Mtr-058518	Medicago truncatula	39.47	5.00e-14	70.90
IUUC-Mga-059307	Meleagris gallopavo	62.90	2.00e-95	343.00
IUUC-Mmr-060699	Microcebus murinus	73.63	0.00e+00	875.00
IUUC-Mdo-062162	Monodelphis domestica	59.88	0.00e+00	627.00
IUUC-Mmu-064188	Mus musculus	87.65	0.00e+00	1009.00
IUUC-Mac-065654	Musa acuminata	41.38	1.00e-13	70.10
IUUC-Mpu-065891	Mustela putorius furo	71.49	0.00e+00	801.00
IUUC-Mlu-067177	Myotis lucifugus	70.71	0.00e+00	780.00
IUUC-Nle-069127	Nomascus leucogenys	71.03	0.00e+00	852.00
IUUC-Ont-072086	Oreochromis niloticus	57.65	1.00e-87	317.00
IUUC-Ocu-074281	Oryctolagus cuniculus	75.00	4.00e-52	196.00
IUUC-Oba-075544	Oryza barthii	45.07	4.00e-14	70.90
IUUC-Ogl-077537	Oryza glaberrima	45.07	4.00e-14	70.90
IUUC-Oin-079590	Oryza indica	45.07	6.00e-14	70.10
IUUC-Olo-080739	Oryza longistaminata	48.33	9.00e-13	67.40
IUUC-Ome-081556	Oryza meridionalis	40.38	3.00e-14	72.00
IUUC-Oni-082676	Oryza nivara	45.07	4.00e-14	70.90
IUUC-Oru-084922	Oryza rufipogon	45.00	1.00e-13	70.90
IUUC-Osa-085384	Oryza sativa	45.00	2.00e-14	72.00
IUUC-Ola-087452	Oryzias latipes	59.06	8.00e-87	314.00
IUUC-Oga-088750	Otolemur garnettii	73.04	0.00e+00	864.00
IUUC-Oar-089523	Ovis aries	63.91	0.00e+00	684.00
IUUC-Ptr-091533	Pan troglodytes	71.32	0.00e+00	844.00
IUUC-Pan-092675	Papio anubis	70.55	0.00e+00	832.00
IUUC-Psi-093735	Pelodiscus sinensis	54.95	3.00e-165	575.00
IUUC-Pab-098486	Pongo abelii	71.32	0.00e+00	865.00
IUUC-Pca-100143	Procavia capensis	70.77	2.00e-141	496.00
IUUC-Ppe-101804	Prunus persica	33.33	3.00e-13	69.70
IUUC-Pva-103151	Pteropus vampyrus	69.02	0.00e+00	784.00
IUUC-Sha-106681	Sarcophilus harrisii	60.21	0.00e+00	644.00
IUUC-Smo-109214	Selaginella moellendorffii	45.35	4.00e-15	75.10
IUUC-Sar-113229	Sorex araneus	71.91	2.00e-108	386.00
IUUC-Ssc-115345	Sus scrofa	53.21	1.00e-63	238.00
IUUC-Tgu-117477	Taeniopygia guttata	52.90	3.00e-143	502.00
IUUC-Tru-118302	Takifugu rubripes	57.81	2.00e-86	313.00
IUUC-Tsy-119338	Tarsius syrichta	60.53	0.00e+00	629.00
IUUC-Tni-119675	Tetraodon nigroviridis	53.10	2.00e-73	270.00
IUUC-Tca-120922	Theobroma cacao	50.00	4.00e-13	68.90
IUUC-Tae-123899	Triticum aestivum	42.31	2.00e-14	72.00
IUUC-Tur-125977	Triticum urartu	41.30	5.00e-15	75.10
IUUC-Tbe-127505	Tupaia belangeri	65.87	2.00e-72	266.00
IUUC-Ttr-128367	Tursiops truncatus	68.92	0.00e+00	688.00
IUUC-Vpa-130480	Vicugna pacos	72.01	2.00e-118	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence