iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088350

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03128293

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000000312.2	ENSOGAT00000000314.2	ENSOGAP00000000280.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.00e-18	66.3	254	301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 254  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 301
           8*********88.6*******************.*******7.******75 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAGVGPGGYA AEFVPPPECP VFEPSWEEFT DPLSFIGRIR PLAEKTGICK IRPPKDWQPP 60
FACEVKSFRF TPRVQRLNEL EIVASKGGFE MVTKEKKWSK VGSRLGYLPG KGTGSLLKSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAATAACA AACGAGAGAA GGAAGCGGTT GCGGGGTTTC CGTGTTGAAC GGTTCGTGTC 60
CGAGAAGATG CGCTTCGGGC CCTGGCAGGG AACGTGAAAG GGCTTGGCGA GCTTCAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	30.89	6.00e-97	349.00
IUUC-Aml-002061	Ailuropoda melanoleuca	96.21	0.00e+00	2898.00
IUUC-Atr-002595	Amborella trichopoda	30.01	3.00e-122	434.00
IUUC-Apl-004141	Anas platyrhynchos	90.17	0.00e+00	2732.00
IUUC-Aca-004952	Anolis carolinensis	88.53	0.00e+00	2738.00
IUUC-Aly-006097	Arabidopsis lyrata	63.64	4.00e-09	58.50
IUUC-Ath-007218	Arabidopsis thaliana	63.64	5.00e-09	58.20
IUUC-Ani-009139	Aspergillus nidulans	33.55	8.00e-109	389.00
IUUC-Ame-011323	Astyanax mexicanus	77.15	0.00e+00	2075.00
IUUC-Bgr-012241	Blumeria graminis	30.23	9.00e-115	409.00
IUUC-Bta-012902	Bos taurus	95.10	0.00e+00	2898.00
IUUC-Cja-018988	Callithrix jacchus	96.19	0.00e+00	2800.00
IUUC-Cfa-020212	Canis familiaris	95.21	0.00e+00	2860.00
IUUC-Cpo-022221	Cavia porcellus	97.51	0.00e+00	2107.00
IUUC-Csa-023575	Chlorocebus sabaeus	96.18	0.00e+00	2780.00
IUUC-Cho-024280	Choloepus hoffmanni	90.95	0.00e+00	2660.00
IUUC-Cin-025321	Ciona intestinalis	48.81	0.00e+00	1074.00
IUUC-Dre-027909	Danio rerio	75.81	0.00e+00	1655.00
IUUC-Dno-029473	Dasypus novemcinctus	97.94	0.00e+00	2634.00
IUUC-Dor-030281	Dipodomys ordii	96.06	0.00e+00	1231.00
IUUC-Eca-034265	Equus caballus	94.68	0.00e+00	2900.00
IUUC-Fca-035476	Felis catus	95.15	0.00e+00	2893.00
IUUC-Fal-037078	Ficedula albicollis	89.25	0.00e+00	2413.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.23	5.00e-110	393.00
IUUC-Gga-040466	Gallus gallus	88.98	0.00e+00	2810.00
IUUC-Gac-042566	Gasterosteus aculeatus	73.90	0.00e+00	2036.00
IUUC-Ggo-044524	Gorilla gorilla	91.66	0.00e+00	2520.00
IUUC-Hsa-045821	Homo sapiens	96.09	0.00e+00	2895.00
IUUC-Kpa-049245	Komagataella pastoris	22.18	5.00e-29	124.00
IUUC-Lch-050630	Latimeria chalumnae	72.60	0.00e+00	2031.00
IUUC-Loc-051963	Lepisosteus oculatus	74.18	0.00e+00	1995.00
IUUC-Laf-053918	Loxodonta africana	88.75	0.00e+00	2484.00
IUUC-Mcc-055672	Macaca mulatta	94.75	0.00e+00	2878.00
IUUC-Meu-056374	Macropus eugenii	78.05	0.00e+00	1297.00
IUUC-Mor-057198	Magnaporthe oryzae	30.25	2.00e-120	427.00
IUUC-Mpo-057317	Magnaporthe poae	30.44	2.00e-111	398.00
IUUC-Mga-059192	Meleagris gallopavo	81.05	0.00e+00	2355.00
IUUC-Mmr-060968	Microcebus murinus	95.04	0.00e+00	2937.00
IUUC-Mdo-062945	Monodelphis domestica	93.29	0.00e+00	2699.00
IUUC-Mmu-063614	Mus musculus	94.73	0.00e+00	2865.00
IUUC-Mpu-066349	Mustela putorius furo	95.90	0.00e+00	2771.00
IUUC-Mlu-067363	Myotis lucifugus	95.56	0.00e+00	2950.00
IUUC-Nfi-068430	Neosartorya fischeri	34.15	7.00e-111	395.00
IUUC-Nle-070142	Nomascus leucogenys	96.15	0.00e+00	2905.00
IUUC-Opr-071002	Ochotona princeps	91.34	0.00e+00	1400.00
IUUC-Ont-072471	Oreochromis niloticus	78.54	0.00e+00	1889.00
IUUC-Oan-072797	Ornithorhynchus anatinus	76.24	0.00e+00	1919.00
IUUC-Ocu-074164	Oryctolagus cuniculus	94.68	0.00e+00	2957.00
IUUC-Oba-075388	Oryza barthii	28.57	8.00e-72	266.00
IUUC-Obr-076296	Oryza brachyantha	34.25	1.00e-94	342.00
IUUC-Ome-081764	Oryza meridionalis	30.95	1.00e-89	325.00
IUUC-Oni-083012	Oryza nivara	28.57	9.00e-72	266.00
IUUC-Oru-084630	Oryza rufipogon	28.62	6.00e-72	266.00
IUUC-Ola-087076	Oryzias latipes	73.40	0.00e+00	2025.00
IUUC-Oar-090045	Ovis aries	94.90	0.00e+00	2883.00
IUUC-Ptr-091199	Pan troglodytes	95.56	0.00e+00	2880.00
IUUC-Pan-092094	Papio anubis	91.55	0.00e+00	2809.00
IUUC-Psi-093550	Pelodiscus sinensis	89.51	0.00e+00	2662.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.39	3.00e-119	423.00
IUUC-Pfo-097266	Poecilia formosa	78.50	0.00e+00	1863.00
IUUC-Pab-098576	Pongo abelii	96.27	0.00e+00	2892.00
IUUC-Pca-100123	Procavia capensis	94.24	0.00e+00	1653.00
IUUC-Ppe-101504	Prunus persica	32.53	2.00e-103	371.00
IUUC-Pva-103109	Pteropus vampyrus	89.88	0.00e+00	2733.00
IUUC-Pte-104195	Pyrenophora teres	29.86	5.00e-122	433.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	29.95	9.00e-124	439.00
IUUC-Rno-105664	Rattus norvegicus	94.67	0.00e+00	2864.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.04	1.00e-72	268.00
IUUC-Sha-107506	Sarcophilus harrisii	94.20	0.00e+00	2548.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.89	1.00e-34	142.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.71	9.00e-53	202.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	62.40
IUUC-Sit-110534	Setaria italica	32.10	7.00e-106	379.00
IUUC-Sly-111298	Solanum lycopersicum	32.09	7.00e-102	366.00
IUUC-Sar-113052	Sorex araneus	94.56	0.00e+00	2887.00
IUUC-Tgu-116613	Taeniopygia guttata	88.97	0.00e+00	2724.00
IUUC-Tru-118604	Takifugu rubripes	73.34	0.00e+00	2075.00
IUUC-Tsy-119237	Tarsius syrichta	98.26	0.00e+00	1311.00
IUUC-Tni-120779	Tetraodon nigroviridis	73.13	0.00e+00	2051.00
IUUC-Tca-121478	Theobroma cacao	32.39	1.00e-105	378.00
IUUC-Tae-125894	Triticum aestivum	31.61	1.00e-98	355.00
IUUC-Tur-126632	Triticum urartu	31.12	4.00e-96	347.00
IUUC-Tme-127087	Tuber melanosporum	30.87	4.00e-132	466.00
IUUC-Tbe-127627	Tupaia belangeri	98.99	0.00e+00	805.00
IUUC-Ttr-129242	Tursiops truncatus	93.31	0.00e+00	2786.00
IUUC-Vda-129733	Verticillium dahliae	29.08	1.00e-105	378.00
IUUC-Vpa-130429	Vicugna pacos	84.80	0.00e+00	1360.00
IUUC-Xtr-131762	Xenopus tropicalis	78.01	0.00e+00	2263.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence