iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088015

Ensembl Protein ID

ENSOGAP00000015385.2

UniProt Accession

H0XH03; H0XH03_OTOGA

Genbank Protein ID

ENSOGAP00000015385

Protein Name

Ribosome biogenesis protein BOP1; Block of proliferation 1 protein

Genbank Nucleotide ID

AAQR03179272

Gene Name

BOP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000017175.2	ENSOGAT00000017180.2	ENSOGAP00000015385.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-19	69.6	394	432

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+d v+cl+  ++   l+sGsdDg++++W++ t +++k
   Q: 394  GHSDLVRCLSVsPGgQWLASGSDDGSLRLWEVATARCVK 432
           8**********988899*******************986 PP

Organism

Otolemur garnettii

Functional Description
(View)

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Protein Sequence
(Fasta)

MAGTRGTKRR QGPELESEPE PEPEPLLEEP SFCTSAPSHG DGRDSGLSDS EESVFSGLDD 60
SGSDSSEDDG HDSVKGTEKT TGEQAQSRPL CPSTEVVHMG NTDEYAEDSS DEEDIRNTVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCA CGCGGGGCAC GAAGCGGCGC CAGGGGCCGG AGCTGGAGTC GGAGCCGGAG 60
CCGGAGCCGG AGCCGCTGCT GGAGGAGGTG ACTGTGGGGT GGCGGGGGCG CTACGAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR028598--BOP1/Erb1
IPR012953--BOP1_N_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08145--BOP1NT
PF00400--WD40

SMART

SM01035--BOP1NT
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0008283--P:cell proliferation
GO:0000448--P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0051726--P:regulation of cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001158	Aegilops tauschii	40.73	2.00e-123	436.00
IUUC-Aml-001507	Ailuropoda melanoleuca	82.85	0.00e+00	1046.00
IUUC-Atr-003141	Amborella trichopoda	41.98	1.00e-86	313.00
IUUC-Apl-003545	Anas platyrhynchos	66.15	0.00e+00	796.00
IUUC-Aly-005649	Arabidopsis lyrata	44.54	2.00e-158	552.00
IUUC-Ath-007625	Arabidopsis thaliana	44.95	4.00e-156	545.00
IUUC-Ago-007958	Ashbya gossypii	42.60	2.00e-160	559.00
IUUC-Acl-008344	Aspergillus clavatus	43.57	3.00e-144	505.00
IUUC-Afl-008616	Aspergillus flavus	42.97	2.00e-146	513.00
IUUC-Afu-009083	Aspergillus fumigatus	44.04	2.00e-141	496.00
IUUC-Ani-009365	Aspergillus nidulans	43.27	2.00e-146	513.00
IUUC-Ang-009796	Aspergillus niger	43.58	2.00e-140	493.00
IUUC-Aor-010015	Aspergillus oryzae	42.97	2.00e-146	513.00
IUUC-Ate-010537	Aspergillus terreus	43.80	2.00e-148	519.00
IUUC-Ame-011767	Astyanax mexicanus	68.80	4.00e-114	403.00
IUUC-Bgr-012286	Blumeria graminis	42.52	6.00e-149	521.00
IUUC-Bta-013569	Bos taurus	87.27	0.00e+00	1102.00
IUUC-Bci-013820	Botrytis cinerea	41.89	9.00e-142	497.00
IUUC-Bdi-014895	Brachypodium distachyon	45.56	7.00e-157	547.00
IUUC-Bol-016099	Brassica oleracea	44.08	6.00e-157	547.00
IUUC-Bra-017174	Brassica rapa	43.92	3.00e-157	550.00
IUUC-Cel-018201	Caenorhabditis elegans	45.75	1.00e-151	530.00
IUUC-Cja-019009	Callithrix jacchus	76.68	0.00e+00	960.00
IUUC-Cfa-020173	Canis familiaris	82.21	0.00e+00	1040.00
IUUC-Cpo-021796	Cavia porcellus	87.48	0.00e+00	1096.00
IUUC-Cre-022650	Chlamydomonas reinhardtii	47.18	2.00e-153	535.00
IUUC-Csa-023440	Chlorocebus sabaeus	89.14	0.00e+00	1154.00
IUUC-Cin-025782	Ciona intestinalis	54.60	0.00e+00	742.00
IUUC-Csv-026352	Ciona savignyi	55.64	0.00e+00	731.00
IUUC-Cgl-026393	Colletotrichum gloeosporioides	38.16	1.00e-113	404.00
IUUC-Cne-027004	Cryptococcus neoformans	42.77	2.00e-166	579.00
IUUC-Cme-027242	Cyanidioschyzon merolae	39.53	3.00e-124	439.00
IUUC-Dre-028658	Danio rerio	71.95	0.00e+00	988.00
IUUC-Dno-028883	Dasypus novemcinctus	80.76	0.00e+00	1099.00
IUUC-Dor-031031	Dipodomys ordii	85.95	0.00e+00	1142.00
IUUC-Dse-031443	Dothistroma septosporum	39.88	1.00e-141	496.00
IUUC-Dme-031786	Drosophila melanogaster	51.79	0.00e+00	720.00
IUUC-Eca-033677	Equus caballus	85.04	0.00e+00	1123.00
IUUC-Eeu-035310	Erinaceus europaeus	86.18	0.00e+00	907.00
IUUC-Fca-035888	Felis catus	84.82	0.00e+00	1071.00
IUUC-Fal-037438	Ficedula albicollis	67.43	0.00e+00	732.00
IUUC-Fox-037973	Fusarium oxysporum	43.25	2.00e-156	546.00
IUUC-Fso-038187	Fusarium solani	42.84	8.00e-155	540.00
IUUC-Gmo-039114	Gadus morhua	65.37	0.00e+00	834.00
IUUC-Ggr-039746	Gaeumannomyces graminis	41.38	1.00e-151	530.00
IUUC-Gga-040631	Gallus gallus	73.16	7.00e-156	543.00
IUUC-Gac-042582	Gasterosteus aculeatus	66.98	0.00e+00	885.00
IUUC-Gma-044215	Glycine max	45.67	3.00e-150	525.00
IUUC-Ggo-045587	Gorilla gorilla	91.57	0.00e+00	1151.00
IUUC-Hsa-046319	Homo sapiens	89.76	0.00e+00	1165.00
IUUC-Hvu-047526	Hordeum vulgare	44.21	1.00e-145	509.00
IUUC-Itr-048683	Ictidomys tridecemlineatus	90.09	0.00e+00	1127.00
IUUC-Kpa-049221	Komagataella pastoris	41.39	5.00e-153	535.00
IUUC-Lch-049640	Latimeria chalumnae	72.41	0.00e+00	1004.00
IUUC-Lpe-051135	Leersia perrieri	42.60	9.00e-135	474.00
IUUC-Loc-051930	Lepisosteus oculatus	72.08	0.00e+00	977.00
IUUC-Lma-053290	Leptosphaeria maculans	42.48	4.00e-142	498.00
IUUC-Laf-053903	Loxodonta africana	77.27	0.00e+00	1003.00
IUUC-Mcc-055471	Macaca mulatta	88.84	0.00e+00	1151.00
IUUC-Meu-056190	Macropus eugenii	84.09	0.00e+00	1056.00
IUUC-Mor-057135	Magnaporthe oryzae	41.99	2.00e-145	509.00
IUUC-Mpo-057475	Magnaporthe poae	40.92	2.00e-140	493.00
IUUC-Mtr-058689	Medicago truncatula	41.34	8.00e-133	467.00
IUUC-Mla-059149	Melampsora laricipopulina	44.67	2.00e-168	586.00
IUUC-Mga-059645	Meleagris gallopavo	63.11	2.00e-97	348.00
IUUC-Mvi-060485	Microbotryum violaceum	44.34	2.00e-147	517.00
IUUC-Mmr-061674	Microcebus murinus	88.59	0.00e+00	1162.00
IUUC-Mdo-062973	Monodelphis domestica	83.09	0.00e+00	1073.00
IUUC-Mmu-064180	Mus musculus	87.44	0.00e+00	1123.00
IUUC-Mac-064535	Musa acuminata	39.59	9.00e-95	341.00
IUUC-Mpu-066406	Mustela putorius furo	87.31	0.00e+00	1128.00
IUUC-Mlu-067795	Myotis lucifugus	88.67	0.00e+00	1092.00
IUUC-Nfi-068516	Neosartorya fischeri	43.72	5.00e-134	471.00
IUUC-Ncr-068767	Neurospora crassa	42.75	6.00e-139	488.00
IUUC-Opr-071084	Ochotona princeps	86.43	9.00e-145	506.00
IUUC-Ont-071614	Oreochromis niloticus	68.98	0.00e+00	923.00
IUUC-Oba-075980	Oryza barthii	42.51	8.00e-136	477.00
IUUC-Obr-076799	Oryza brachyantha	44.82	4.00e-150	525.00
IUUC-Ogl-077134	Oryza glaberrima	44.01	7.00e-145	507.00
IUUC-Ogu-078655	Oryza glumaepatula	42.39	3.00e-139	489.00
IUUC-Oin-079654	Oryza indica	44.01	1.00e-144	506.00
IUUC-Olo-080706	Oryza longistaminata	42.07	1.00e-136	479.00
IUUC-Ome-081716	Oryza meridionalis	38.99	9.00e-119	421.00
IUUC-Oni-082508	Oryza nivara	42.49	9.00e-137	480.00
IUUC-Opu-083707	Oryza punctata	42.18	8.00e-136	477.00
IUUC-Oru-084453	Oryza rufipogon	42.07	1.00e-136	479.00
IUUC-Osa-085811	Oryza sativa	44.01	1.00e-144	506.00
IUUC-Ola-087361	Oryzias latipes	68.54	0.00e+00	936.00
IUUC-Oar-090058	Ovis aries	61.31	3.00e-116	412.00
IUUC-Ptr-090631	Pan troglodytes	81.70	4.00e-140	490.00
IUUC-Pan-092306	Papio anubis	86.20	0.00e+00	1167.00
IUUC-Pma-094622	Petromyzon marinus	71.47	0.00e+00	963.00
IUUC-Pno-094794	Phaeosphaeria nodorum	39.22	3.00e-130	459.00
IUUC-Ppa-095528	Physcomitrella patens	43.56	1.00e-96	347.00
IUUC-Pfo-096682	Poecilia formosa	68.45	0.00e+00	935.00
IUUC-Pab-097939	Pongo abelii	90.23	0.00e+00	1028.00
IUUC-Pop-099530	Populus trichocarpa	45.10	8.00e-140	490.00
IUUC-Pca-100333	Procavia capensis	85.37	0.00e+00	1134.00
IUUC-Ppe-102078	Prunus persica	42.42	6.00e-150	524.00
IUUC-Pgr-103525	Puccinia graminis	45.38	3.00e-160	558.00
IUUC-Ptt-103929	Puccinia triticina	44.98	1.00e-155	543.00
IUUC-Pte-104029	Pyrenophora teres	42.02	7.00e-151	527.00
IUUC-Pyt-104446	Pyrenophora triticirepentis	42.17	3.00e-151	528.00
IUUC-Rno-105248	Rattus norvegicus	86.78	0.00e+00	1120.00
IUUC-Sce-106381	Saccharomyces cerevisiae	40.87	3.00e-154	539.00
IUUC-Sha-106519	Sarcophilus harrisii	83.31	0.00e+00	1078.00
IUUC-Sja-107908	Schizosaccharomyces japonicus	40.57	1.00e-139	490.00
IUUC-Spo-108071	Schizosaccharomyces pombe	41.79	7.00e-142	497.00
IUUC-Smo-109604	Selaginella moellendorffii	45.98	4.00e-156	545.00
IUUC-Sit-109742	Setaria italica	43.94	7.00e-153	534.00
IUUC-Sly-110970	Solanum lycopersicum	46.06	8.00e-82	297.00
IUUC-Stu-112593	Solanum tuberosum	45.63	2.00e-154	539.00
IUUC-Sar-113123	Sorex araneus	84.44	2.00e-146	511.00
IUUC-Sbi-113945	Sorghum bicolor	44.10	3.00e-151	528.00
IUUC-Sre-115188	Sporisorium reilianum	44.02	3.00e-159	555.00
IUUC-Ssc-115352	Sus scrofa	90.11	0.00e+00	1094.00
IUUC-Tru-117685	Takifugu rubripes	69.12	0.00e+00	935.00
IUUC-Tni-119982	Tetraodon nigroviridis	69.77	0.00e+00	894.00
IUUC-Tca-121664	Theobroma cacao	45.31	5.00e-157	548.00
IUUC-Tre-122229	Trichoderma reesei	42.60	7.00e-138	484.00
IUUC-Tvi-122576	Trichoderma virens	42.84	2.00e-142	499.00
IUUC-Tae-124110	Triticum aestivum	44.12	9.00e-138	484.00
IUUC-Tur-126781	Triticum urartu	41.23	3.00e-119	422.00
IUUC-Tme-127080	Tuber melanosporum	45.83	1.00e-171	596.00
IUUC-Ttr-128514	Tursiops truncatus	85.02	0.00e+00	781.00
IUUC-Uma-129556	Ustilago maydis	42.22	3.00e-151	529.00
IUUC-Vda-129715	Verticillium dahliae	42.37	9.00e-149	520.00
IUUC-Vvi-131211	Vitis vinifera	44.98	5.00e-149	521.00
IUUC-Xma-133883	Xiphophorus maculatus	69.00	0.00e+00	902.00
IUUC-Yli-134438	Yarrowia lipolytica	42.73	7.00e-143	501.00
IUUC-Zma-135341	Zea mays	39.29	8.00e-136	477.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence