iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ogu-078010

Ensembl Protein ID

OGLUM08G10950.1

UniProt Accession

A0A0E0ATT1; A0A0E0ATT1_9ORYZ

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OGLUM08G10950	OGLUM08G10950.1	OGLUM08G10950.1
OGLUM08G10950	OGLUM08G10950.3	OGLUM08G10950.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-26	90.8	50	87
UBD/Beta-Prp	8.30e-41	141.2	6	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v++++   d t+l++Gs D t k+WD+ tg+ l
   Q: 50   GHNGAVWSCDVsRDsTRLITGSADQTAKLWDVQTGREL 87
           8***********777*******************9876 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......... 131
           ++ghe + t +++++dg++l ++++D+t +vw  ++g+ + t++gh+  v+s+++s+++ +l++Gs+d+t+++wd++tg +l +          
   Q: 6    MKGHERPLTFLRYNRDGDLLFSCAKDHTPNVWFADNGDRLGTYRGHNGAVWSCDVSRDSTRLITGSADQTAKLWDVQTGRELFTfrfdaparsv 99
           489********************************************************************************9********** PP
   S: 132  .........................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...tgghtd 181
                                                    + +g +g +n +v+ p ++ +++++ D t+r+Wd +tg++l++    + gh++
   Q: 100  efaigdglavittdnfmenvptaqvkriaedpddqseesllVITGIKGRINRAVWGPLNRTIITAGEDATIRIWDTETGQCLKESdkeQ-GHQK 192
           **************************************************************************************955.5*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgec..........................vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
            ++sls + +  ++++gsld++ klwd +t +                           +  ++gh  +++ ++f p++  + sg++Dg +r++
   Q: 193  TITSLSKSADWSHFLTGSLDKSAKLWDTRTLTLiktyvterpvnavdisplldhilqeeIGGVKGHFGPINALAFNPDGRSFSSGGEDGYVRLH 286
           *****************************77773333333344555555555555555555555555*************************98 PP
   S: 250  dlrs 253
             +s
   Q: 287  HFDS 290
           4444 PP

Organism

Oryza glumaepatula

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLRYNR DGDLLFSCAK DHTPNVWFAD NGDRLGTYRG HNGAVWSCDV 60
SRDSTRLITG SADQTAKLWD VQTGRELFTF RFDAPARSVE FAIGDGLAVI TTDNFMENVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCGA TCCTGATGAA GGGGCACGAG CGCCCGCTCA CGTTCCTCCG GTACAACCGC 60
GACGGGGACC TCCTCTTCTC CTGCGCCAAG GACCACACCC CCAACGTCTG GTTCGCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Oba-075395	Oryza barthii	100.00	2.00e-177	613.00
IUUC-Ome-081228	Oryza meridionalis	67.50	1.00e-114	405.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence