iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047781

Ensembl Protein ID

MLOC_44534.1

UniProt Accession

F2DZA4; M0W7I5; F2DZA4_HORVV

Genbank Protein ID

BAK00426.1

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Genbank Nucleotide ID

AK369224

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_44534	MLOC_44534.8	MLOC_44534.8
MLOC_44534	MLOC_44534.1	MLOC_44534.1
MLOC_44534	MLOC_44534.13	MLOC_44534.13
MLOC_44534	MLOC_44534.17	MLOC_44534.17
MLOC_44534	MLOC_44534.16	MLOC_44534.16
MLOC_44534	MLOC_44534.11	MLOC_44534.11
MLOC_44534	MLOC_44534.2	MLOC_44534.2
MLOC_44534	MLOC_44534.12	MLOC_44534.12
MLOC_44534	MLOC_44534.4	MLOC_44534.4
MLOC_44534	MLOC_44534.15	MLOC_44534.15

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-34	117.2	184	219
UBD/Beta-Prp	9.50e-54	183.7	14	263

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+++++cl+f +   ll++Gs D+t+k WDl t+ l
   Q: 184  HEGPINCLDFhPHeFLLATGSADKTVKFWDLETFEL 219
           9*********9776789**************99876 PP
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+++++cl+f +   ll++Gs D+t+k WDl t+ l
   Q: 184  HEGPINCLDFhPHeFLLATGSADKTVKFWDLETFEL 219
           9*********9776789**************99876 PP
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+++++cl+f +   ll++Gs D+t+k WDl t+ l
   Q: 184  HEGPINCLDFhPHeFLLATGSADKTVKFWDLETFEL 219
           9*********9776789**************99876 PP
   S: 5    svtclafsd.tllvsGs.dDgtikvWDlrtgv 34
           +vt l++ d   +v G+ +Dg+++vW++rtg+
   Q: 326  PVTLLHL-DpYKVVMGApWDGQVHVWETRTGH 356
           5777777.4345666666************97 PP
   S: 5    svtclaf..sd.tllvsGsdDgtikvWD 29
            v +++f  ++  +++sGsd g + +W+
   Q: 314  TVKGVSFfgPNnEYVLSGSDCGHVFIWR 341
           58899*99*666***************8 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +h s +tc kf ++ ++ l+tg++d+++ +w v +++++ slsg +++v +++f++++ ++  g+  +tik+wd++  k v+t++gh ++  sl++
   Q: 14   AHASDVTCAKFgKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 109
           67778899*************************************************9888899999***************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsg 198
           +p gd+++sGs+d   ++wd++++ c++ t +gh+g + ++++ pdg+ +vsG++D+ v++Wdl  gkll++++  h++++++l+f++  + l++g
   Q: 110  HPFGDFFASGSSDTNMKIWDMRKKRCIH-TYQGHTGRIDVLRFTPDGRWIVSGGADSSVKIWDLTAGKLLHDFRL-HEGPINCLDFHPHEFLLATG 203
           ****************************.*********************************************8.******************** PP
   S: 199  sldgtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiri..W 249
           s d+tvk+wdl+t e          r++    + v+s+ f ++++ l +g  ++s+++  W
   Q: 204  SADKTVKFWDLETFELigssgpenCREYYVPGSVVRSMTFNSDGKALFCGL-HESLKVlsW 263
           ************65554555555588888999**************99995.555555445 PP
   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +h s +tc kf ++ ++ l+tg++d+++ +w v +++++ slsg +++v +++f++++ ++  g+  +tik+wd++  k v+t++gh ++  sl++
   Q: 14   AHASDVTCAKFgKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 109
           67778899*************************************************9888899999***************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsg 198
           +p gd+++sGs+d   ++wd++++ c++ t +gh+g + ++++ pdg+ +vsG++D+ v++Wdl  gkll++++  h++++++l+f++  + l++g
   Q: 110  HPFGDFFASGSSDTNMKIWDMRKKRCIH-TYQGHTGRIDVLRFTPDGRWIVSGGADSSVKIWDLTAGKLLHDFRL-HEGPINCLDFHPHEFLLATG 203
           ****************************.*********************************************8.******************** PP
   S: 199  sldgtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiri..W 249
           s d+tvk+wdl+t e          r++    + v+s+ f ++++ l +g  ++s+++  W
   Q: 204  SADKTVKFWDLETFELigssgpenCREYYVPGSVVRSMTFNSDGKALFCGL-HESLKVlsW 263
           ************65554555555588888999**************99995.555555446 PP
   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           +h s +tc kf ++ ++ l+tg++d+++ +w v +++++ slsg +++v +++f++++ ++  g+  +tik+wd++  k v+t++gh ++  sl+++
   Q: 14   AHASDVTCAKFgKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSH 110
           67778899*************************************************9888899999****************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsl 200
           p gd+++sGs+d   ++wd++++ c++ t +gh+g + ++++ pdg+ +vsG++D+ v++Wdl  gkll++++  h++++++l+f++  + l++gs 
   Q: 111  PFGDFFASGSSDTNMKIWDMRKKRCIH-TYQGHTGRIDVLRFTPDGRWIVSGGADSSVKIWDLTAGKLLHDFRL-HEGPINCLDFHPHEFLLATGSA 205
           ***************************.*********************************************8.********************** PP
   S: 201  dgtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiri..W 249
           d+tvk+wdl+t e          r++    + v+s+ f ++++ l +g  ++s+++  W
   Q: 206  DKTVKFWDLETFELigssgpenCREYYVPGSVVRSMTFNSDGKALFCGL-HESLKVlsW 263
           **********65554555555588888999*************999995.555555445 PP

Organism

Hordeum vulgare

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MATKRAYKLQ EFVAHASDVT CAKFGKRTSR TLITGGEDQK VNLWAVGKPT AVLSLSGLTS 60
PVESLSFDSS EVMIGAGAAS GTIKIWDIEE AKVVRTFTGH RSNCASLDSH PFGDFFASGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTCTTTA GAGTTGCTTT TCCCCTCGCC TCTCTCTCTC CCTCTCACTA GTTTGTTCCT 60
ATAAAATCGG GCGGATTTGT AGCACCAAAC GAGAAACGGC ATACAATAAG GGACCGATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0051013--P:microtubule severing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000873	Aegilops tauschii	80.46	0.00e+00	1305.00
IUUC-Atr-002899	Amborella trichopoda	46.90	0.00e+00	650.00
IUUC-Bdi-014552	Brachypodium distachyon	77.41	0.00e+00	1230.00
IUUC-Gma-044134	Glycine max	46.02	0.00e+00	655.00
IUUC-Lpe-051597	Leersia perrieri	73.87	0.00e+00	684.00
IUUC-Oba-075845	Oryza barthii	62.76	0.00e+00	1007.00
IUUC-Obr-076798	Oryza brachyantha	62.80	0.00e+00	1055.00
IUUC-Ogu-079022	Oryza glumaepatula	63.90	0.00e+00	1045.00
IUUC-Oin-080135	Oryza indica	64.58	0.00e+00	1056.00
IUUC-Olo-080665	Oryza longistaminata	62.03	0.00e+00	877.00
IUUC-Ome-081884	Oryza meridionalis	64.06	0.00e+00	1031.00
IUUC-Oni-082726	Oryza nivara	62.87	0.00e+00	1006.00
IUUC-Opu-083637	Oryza punctata	63.85	0.00e+00	1064.00
IUUC-Oru-085123	Oryza rufipogon	64.46	0.00e+00	1053.00
IUUC-Osa-086267	Oryza sativa	64.46	0.00e+00	1053.00
IUUC-Sit-109837	Setaria italica	59.20	0.00e+00	962.00
IUUC-Stu-112053	Solanum tuberosum	43.84	0.00e+00	631.00
IUUC-Tae-123176	Triticum aestivum	88.53	0.00e+00	1412.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence