iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106660

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01000522

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017705.1	ENSSHAT00000021046.1	ENSSHAP00000020877.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-44	147.0	19	58
UBD/Beta-Prp	1.10e-74	251.5	16	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.....sd.tllvsGsdDgtikvWDlrtgvl 35
           H d ++++a+     ++  ++vsGs D  +kvW +++ +l
   Q: 19   HDDAIWSVAWglnqkDNsEMIVSGSLDDLVKVWKWKSEKL 58
           99************8446****************998776 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++++++gs d+ +kvw+++++kl   +sl+gh+ +v +v++s++g i +++s D++i++wdl++gk++ 
   Q: 16   EQAHDDAIWSVAWglnqKDNSEMIVSGSLDDLVKVWKWKSEKLelQWSLEGHQLGVVSVDISQSGAIAASSSLDAHIRLWDLENGKQMK 104
           56777788889999988999**********************99899****************************************** PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp++++l++Gsh+  ++++ +etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 105  SIDAGPVDAWSLAFSPDSQFLATGSHVGKVNIFGVETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 192
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d ++vs ssD+s+++Wd  ++++++t+  h+++
   Q: 193  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDIHFVSSSSDKSVKVWDAGTRTCVHTFFDHQDQ 280
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 281  VWGVKY-NATGSKIVSVGDDQEIHIYDC 307
           ******.*******************98 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MGFLFFFQYS ILFKQEQAHD DAIWSVAWGL NQKDNSEMIV SGSLDDLVKV WKWKSEKLEL 60
QWSLEGHQLG VVSVDISQSG AIAASSSLDA HIRLWDLENG KQMKSIDAGP VDAWSLAFSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGCCCGA GGAGTTACGT CATTGATGAT CTCTTCCCTT GTGGCACCTC CTTCTATTGG 60
GGGCGTCCTC CCCCGACCTC CCAGACCGCG CTTCGGGACC CCCGTGGGGA AGCACAGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

shr:100925814

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	33.43	4.00e-47	181.00
IUUC-Aml-002245	Ailuropoda melanoleuca	92.03	5.00e-156	543.00
IUUC-Atr-003142	Amborella trichopoda	51.55	1.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	91.36	7.00e-156	542.00
IUUC-Aca-004880	Anolis carolinensis	88.04	6.00e-154	536.00
IUUC-Aly-005956	Arabidopsis lyrata	37.70	8.00e-57	213.00
IUUC-Ath-007230	Arabidopsis thaliana	36.86	4.00e-51	194.00
IUUC-Acl-008297	Aspergillus clavatus	30.74	4.00e-25	108.00
IUUC-Ame-011511	Astyanax mexicanus	85.48	6.00e-149	519.00
IUUC-Bgr-012189	Blumeria graminis	31.45	1.00e-29	123.00
IUUC-Bta-012936	Bos taurus	92.69	2.00e-156	544.00
IUUC-Bdi-015020	Brachypodium distachyon	37.46	1.00e-46	179.00
IUUC-Bol-015927	Brassica oleracea	37.50	1.00e-57	216.00
IUUC-Bra-017323	Brassica rapa	37.70	3.00e-57	215.00
IUUC-Cja-019961	Callithrix jacchus	92.03	7.00e-156	542.00
IUUC-Cfa-020862	Canis familiaris	91.69	4.00e-155	540.00
IUUC-Cpo-021356	Cavia porcellus	92.03	2.00e-155	541.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.72	1.00e-56	213.00
IUUC-Csa-024067	Chlorocebus sabaeus	91.69	3.00e-155	540.00
IUUC-Cho-024421	Choloepus hoffmanni	79.70	3.00e-79	287.00
IUUC-Cin-025261	Ciona intestinalis	65.12	1.00e-115	408.00
IUUC-Cne-026846	Cryptococcus neoformans	29.03	8.00e-25	107.00
IUUC-Dre-027706	Danio rerio	67.11	2.00e-110	392.00
IUUC-Dno-029084	Dasypus novemcinctus	91.75	6.00e-155	539.00
IUUC-Dor-030353	Dipodomys ordii	80.15	1.00e-114	405.00
IUUC-Dse-031348	Dothistroma septosporum	30.17	6.00e-26	110.00
IUUC-Dme-031836	Drosophila melanogaster	51.08	2.00e-88	318.00
IUUC-Ete-032261	Echinops telfairi	90.37	3.00e-151	527.00
IUUC-Eca-034231	Equus caballus	84.39	6.00e-141	493.00
IUUC-Eeu-034828	Erinaceus europaeus	91.03	5.00e-147	513.00
IUUC-Fca-036569	Felis catus	92.36	7.00e-156	542.00
IUUC-Fal-037469	Ficedula albicollis	92.69	4.00e-158	550.00
IUUC-Gmo-039579	Gadus morhua	85.71	5.00e-146	509.00
IUUC-Gga-040808	Gallus gallus	93.47	4.00e-153	533.00
IUUC-Gac-042100	Gasterosteus aculeatus	85.71	1.00e-146	512.00
IUUC-Gma-043509	Glycine max	40.19	3.00e-61	228.00
IUUC-Ggo-045227	Gorilla gorilla	92.03	7.00e-156	542.00
IUUC-Hsa-045839	Homo sapiens	92.03	7.00e-156	542.00
IUUC-Hvu-047591	Hordeum vulgare	37.50	4.00e-49	187.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	92.36	1.00e-156	545.00
IUUC-Lch-049549	Latimeria chalumnae	83.06	3.00e-143	500.00
IUUC-Lpe-050746	Leersia perrieri	38.59	2.00e-48	186.00
IUUC-Loc-052540	Lepisosteus oculatus	86.71	2.00e-146	511.00
IUUC-Lma-052992	Leptosphaeria maculans	29.01	3.00e-27	115.00
IUUC-Laf-053907	Loxodonta africana	92.36	1.00e-156	545.00
IUUC-Mcc-055828	Macaca mulatta	85.98	1.00e-151	528.00
IUUC-Meu-056075	Macropus eugenii	98.44	3.00e-140	490.00
IUUC-Mor-056971	Magnaporthe oryzae	31.84	3.00e-24	105.00
IUUC-Mtr-057728	Medicago truncatula	40.71	2.00e-58	219.00
IUUC-Mga-059872	Meleagris gallopavo	93.36	5.00e-159	553.00
IUUC-Mvi-060564	Microbotryum violaceum	31.88	6.00e-31	127.00
IUUC-Mmr-060985	Microcebus murinus	92.44	1.00e-150	525.00
IUUC-Mdo-062758	Monodelphis domestica	95.68	4.00e-164	570.00
IUUC-Mmu-063580	Mus musculus	91.36	2.00e-155	541.00
IUUC-Mac-064880	Musa acuminata	40.19	6.00e-59	220.00
IUUC-Mpu-066577	Mustela putorius furo	91.36	2.00e-154	537.00
IUUC-Nle-069573	Nomascus leucogenys	92.03	7.00e-156	542.00
IUUC-Opr-070216	Ochotona princeps	91.00	3.00e-154	537.00
IUUC-Ont-071981	Oreochromis niloticus	86.38	4.00e-149	520.00
IUUC-Oan-073223	Ornithorhynchus anatinus	96.94	3.00e-109	386.00
IUUC-Ocu-074199	Oryctolagus cuniculus	78.48	5.00e-128	450.00
IUUC-Oba-075255	Oryza barthii	40.77	9.00e-42	163.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	143.00
IUUC-Ogl-077777	Oryza glaberrima	38.39	4.00e-49	187.00
IUUC-Ogu-078780	Oryza glumaepatula	38.39	4.00e-49	187.00
IUUC-Oin-079228	Oryza indica	38.39	1.00e-51	196.00
IUUC-Olo-080617	Oryza longistaminata	45.77	2.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.39	3.00e-48	185.00
IUUC-Oni-082997	Oryza nivara	38.39	1.00e-51	196.00
IUUC-Opu-083931	Oryza punctata	38.71	4.00e-49	187.00
IUUC-Oru-084645	Oryza rufipogon	38.39	4.00e-49	187.00
IUUC-Osa-085842	Oryza sativa	38.39	1.00e-51	196.00
IUUC-Ola-086696	Oryzias latipes	86.38	7.00e-145	506.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.44	4.00e-41	160.00
IUUC-Oga-088272	Otolemur garnettii	91.39	7.00e-155	539.00
IUUC-Oar-089416	Ovis aries	92.69	2.00e-156	544.00
IUUC-Ptr-090944	Pan troglodytes	92.03	7.00e-156	542.00
IUUC-Pan-091861	Papio anubis	92.03	7.00e-156	542.00
IUUC-Psi-093750	Pelodiscus sinensis	92.36	5.00e-157	546.00
IUUC-Pma-094608	Petromyzon marinus	82.03	3.00e-136	477.00
IUUC-Pno-094832	Phaeosphaeria nodorum	31.58	3.00e-25	108.00
IUUC-Ppa-095737	Physcomitrella patens	39.42	1.00e-57	216.00
IUUC-Pfo-096479	Poecilia formosa	86.71	3.00e-142	497.00
IUUC-Pab-098179	Pongo abelii	92.03	7.00e-156	542.00
IUUC-Pop-099532	Populus trichocarpa	40.91	2.00e-57	216.00
IUUC-Pca-100664	Procavia capensis	71.43	1.00e-97	348.00
IUUC-Ppe-102056	Prunus persica	39.94	4.00e-59	221.00
IUUC-Pva-102859	Pteropus vampyrus	92.03	2.00e-155	541.00
IUUC-Pte-104236	Pyrenophora teres	35.71	1.00e-24	106.00
IUUC-Rno-105826	Rattus norvegicus	91.36	9.00e-155	538.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	34.22	5.00e-37	147.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.37	3.00e-33	135.00
IUUC-Smo-109382	Selaginella moellendorffii	42.81	8.00e-63	233.00
IUUC-Sit-110048	Setaria italica	37.11	4.00e-40	158.00
IUUC-Sly-111618	Solanum lycopersicum	38.14	6.00e-52	197.00
IUUC-Stu-112543	Solanum tuberosum	37.82	1.00e-54	206.00
IUUC-Sar-113743	Sorex araneus	72.76	4.00e-119	420.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	2.00e-41	162.00
IUUC-Ssc-115560	Sus scrofa	88.04	3.00e-146	510.00
IUUC-Tgu-117300	Taeniopygia guttata	93.02	1.00e-158	551.00
IUUC-Tru-117933	Takifugu rubripes	86.05	3.00e-148	517.00
IUUC-Tsy-119574	Tarsius syrichta	81.40	3.00e-132	464.00
IUUC-Tni-120191	Tetraodon nigroviridis	87.71	6.00e-113	399.00
IUUC-Tca-120983	Theobroma cacao	40.13	2.00e-58	218.00
IUUC-Tae-124056	Triticum aestivum	35.96	3.00e-49	188.00
IUUC-Tur-126711	Triticum urartu	35.11	1.00e-47	182.00
IUUC-Tme-127066	Tuber melanosporum	33.46	3.00e-34	139.00
IUUC-Tbe-127802	Tupaia belangeri	92.36	7.00e-156	542.00
IUUC-Ttr-128861	Tursiops truncatus	89.60	3.00e-51	194.00
IUUC-Vda-129720	Verticillium dahliae	31.25	1.00e-23	103.00
IUUC-Vpa-130618	Vicugna pacos	91.85	3.00e-125	440.00
IUUC-Vvi-130981	Vitis vinifera	40.71	4.00e-58	218.00
IUUC-Xtr-132460	Xenopus tropicalis	87.04	3.00e-146	510.00
IUUC-Xma-134154	Xiphophorus maculatus	86.71	2.00e-142	498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence