iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060150

UUCD1 version

UUC-MeG-00577

Ensembl Protein ID

ENSMGAP00000013377.1

UniProt Accession

G1NJ85; G1NJ85_MELGA

Protein Name

Uncharacterized protein

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000012690.1	ENSMGAT00000014283.1	ENSMGAP00000013377.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-39	131.8	231	261
UBD/Beta-Prp	5.20e-62	209.4	53	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d + l+s+s+D+t k+WD+
   Q: 231  HDGGIYAISWsPDsCQLLSASGDKTAKIWDV 261
           99*********999****************8 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           ++h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++
   Q: 53   TEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDLAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEIT 141
           4566667778*************************998777742334567***********99999999887777777789******** PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tg 177
           gh++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    tls h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   +
   Q: 142  GHNKVINSVDIKQTRpYRLATGSDDNCAAFFEGPPFKFKF-TLSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALggGK 229
           *************999*******************99999.********************************************9955 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           +h++ +y +s+++++ +l+s+s d+t k+wd+ ++++v t+n  ++   
   Q: 230  AHDGGIYAISWSPDSCQLLSASGDKTAKIWDVGANSVVSTFNMGSNVLD 278
           6***************************************997665443 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FPVEKVFASL PQVERGVSKI IGGDPKGNNF LYTNGKCVVI RNIDNPAIAD IYTEHAHQVV 60
VAKYAPSGFY IASGDVSGKL RIWDTTQKEH LLKYEYQPFA GKIKDLAWTE DSKRIAVVGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCCTGTAG AAAAAGTGTT CGCCAGCCTC CCGCAGGTTG AACGAGGCGT GTCCAAAATC 60
ATTGGAGGTG ATCCGAAAGG CAACAATTTT CTCTATACCA ATGGGAAATG CGTCGTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.80	6.00e-85	307.00
IUUC-Aml-002368	Ailuropoda melanoleuca	89.52	0.00e+00	1110.00
IUUC-Atr-003160	Amborella trichopoda	37.95	1.00e-116	413.00
IUUC-Apl-004012	Anas platyrhynchos	96.36	0.00e+00	1157.00
IUUC-Aca-004707	Anolis carolinensis	84.88	0.00e+00	1063.00
IUUC-Aly-006465	Arabidopsis lyrata	39.12	2.00e-115	409.00
IUUC-Ath-006740	Arabidopsis thaliana	38.96	6.00e-114	404.00
IUUC-Ago-007920	Ashbya gossypii	28.21	4.00e-75	275.00
IUUC-Acl-008262	Aspergillus clavatus	36.93	1.00e-109	389.00
IUUC-Afl-008471	Aspergillus flavus	33.33	7.00e-80	291.00
IUUC-Afu-008989	Aspergillus fumigatus	38.92	6.00e-99	354.00
IUUC-Ani-009167	Aspergillus nidulans	37.97	2.00e-116	412.00
IUUC-Ang-009595	Aspergillus niger	38.83	2.00e-104	372.00
IUUC-Aor-009908	Aspergillus oryzae	36.54	2.00e-103	369.00
IUUC-Ate-010580	Aspergillus terreus	37.89	2.00e-109	390.00
IUUC-Ame-011269	Astyanax mexicanus	61.87	7.00e-135	473.00
IUUC-Bgr-011996	Blumeria graminis	34.04	5.00e-106	378.00
IUUC-Bta-013278	Bos taurus	89.40	0.00e+00	1140.00
IUUC-Bci-013925	Botrytis cinerea	36.33	2.00e-110	392.00
IUUC-Bdi-014659	Brachypodium distachyon	36.02	1.00e-106	379.00
IUUC-Bol-016043	Brassica oleracea	37.11	1.00e-111	396.00
IUUC-Bra-017139	Brassica rapa	38.01	6.00e-113	400.00
IUUC-Cel-018417	Caenorhabditis elegans	40.16	1.00e-121	429.00
IUUC-Cja-019952	Callithrix jacchus	87.75	0.00e+00	1079.00
IUUC-Cfa-020225	Canis familiaris	88.91	0.00e+00	1110.00
IUUC-Cpo-021900	Cavia porcellus	88.52	0.00e+00	1107.00
IUUC-Csa-023028	Chlorocebus sabaeus	88.58	0.00e+00	1089.00
IUUC-Cho-025030	Choloepus hoffmanni	64.83	0.00e+00	713.00
IUUC-Cin-025152	Ciona intestinalis	55.16	2.00e-80	291.00
IUUC-Csv-025986	Ciona savignyi	37.85	4.00e-94	338.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.69	1.00e-115	409.00
IUUC-Cne-026814	Cryptococcus neoformans	35.13	5.00e-98	351.00
IUUC-Dre-027498	Danio rerio	79.79	1.00e-94	337.00
IUUC-Dno-029383	Dasypus novemcinctus	87.91	0.00e+00	1072.00
IUUC-Dor-030633	Dipodomys ordii	87.14	0.00e+00	1018.00
IUUC-Dse-031526	Dothistroma septosporum	38.76	1.00e-116	412.00
IUUC-Dme-031597	Drosophila melanogaster	47.59	2.00e-168	585.00
IUUC-Ete-032780	Echinops telfairi	82.03	0.00e+00	994.00
IUUC-Eca-034306	Equus caballus	87.69	0.00e+00	1078.00
IUUC-Eeu-034531	Erinaceus europaeus	70.09	6.00e-129	453.00
IUUC-Fca-036301	Felis catus	89.52	0.00e+00	1134.00
IUUC-Fal-037361	Ficedula albicollis	95.87	0.00e+00	1207.00
IUUC-Fox-037924	Fusarium oxysporum	35.80	2.00e-104	372.00
IUUC-Fso-038199	Fusarium solani	34.98	5.00e-100	358.00
IUUC-Gmo-039238	Gadus morhua	72.07	0.00e+00	894.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.68	5.00e-98	351.00
IUUC-Gga-040235	Gallus gallus	98.68	0.00e+00	1197.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.14	0.00e+00	929.00
IUUC-Gma-044189	Glycine max	37.70	1.00e-115	409.00
IUUC-Ggo-044632	Gorilla gorilla	86.45	0.00e+00	1055.00
IUUC-Hsa-045792	Homo sapiens	88.25	0.00e+00	1103.00
IUUC-Hvu-047517	Hordeum vulgare	36.01	2.00e-110	392.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	89.35	0.00e+00	1108.00
IUUC-Kpa-049183	Komagataella pastoris	33.83	8.00e-90	323.00
IUUC-Lch-050428	Latimeria chalumnae	77.69	0.00e+00	1013.00
IUUC-Lpe-051306	Leersia perrieri	36.89	1.00e-112	399.00
IUUC-Loc-052096	Lepisosteus oculatus	72.80	0.00e+00	905.00
IUUC-Lma-053313	Leptosphaeria maculans	38.99	1.00e-117	419.00
IUUC-Laf-054060	Loxodonta africana	86.92	0.00e+00	1076.00
IUUC-Mcc-055619	Macaca mulatta	87.31	0.00e+00	1068.00
IUUC-Meu-056689	Macropus eugenii	76.52	3.00e-179	621.00
IUUC-Mor-056940	Magnaporthe oryzae	37.03	2.00e-99	356.00
IUUC-Mpo-057557	Magnaporthe poae	31.00	3.00e-71	262.00
IUUC-Mtr-057922	Medicago truncatula	36.11	9.00e-113	400.00
IUUC-Mla-059103	Melampsora laricipopulina	33.27	9.00e-77	280.00
IUUC-Mvi-060448	Microbotryum violaceum	31.78	2.00e-78	286.00
IUUC-Mmr-061226	Microcebus murinus	87.58	0.00e+00	1080.00
IUUC-Mdo-062674	Monodelphis domestica	89.40	0.00e+00	1125.00
IUUC-Mmu-064170	Mus musculus	88.41	0.00e+00	1108.00
IUUC-Mac-065124	Musa acuminata	39.02	2.00e-116	412.00
IUUC-Mpu-066001	Mustela putorius furo	85.17	0.00e+00	1087.00
IUUC-Mlu-067253	Myotis lucifugus	89.18	0.00e+00	1111.00
IUUC-Nfi-068550	Neosartorya fischeri	38.73	3.00e-112	398.00
IUUC-Ncr-068948	Neurospora crassa	36.82	5.00e-114	404.00
IUUC-Nle-070115	Nomascus leucogenys	86.15	0.00e+00	993.00
IUUC-Opr-070254	Ochotona princeps	86.33	0.00e+00	1042.00
IUUC-Ont-071666	Oreochromis niloticus	75.66	0.00e+00	962.00
IUUC-Oan-073594	Ornithorhynchus anatinus	88.02	5.00e-161	559.00
IUUC-Ocu-074824	Oryctolagus cuniculus	86.75	0.00e+00	1061.00
IUUC-Oba-075010	Oryza barthii	36.56	3.00e-112	398.00
IUUC-Obr-076364	Oryza brachyantha	38.73	4.00e-115	408.00
IUUC-Ogl-077019	Oryza glaberrima	36.56	3.00e-112	398.00
IUUC-Ogu-078496	Oryza glumaepatula	36.56	3.00e-112	398.00
IUUC-Oin-080116	Oryza indica	36.72	2.00e-112	399.00
IUUC-Olo-080290	Oryza longistaminata	36.56	8.00e-112	397.00
IUUC-Ome-081969	Oryza meridionalis	36.56	4.00e-112	398.00
IUUC-Oni-082075	Oryza nivara	36.56	3.00e-112	398.00
IUUC-Opu-083959	Oryza punctata	36.89	8.00e-113	400.00
IUUC-Oru-084711	Oryza rufipogon	36.56	3.00e-112	398.00
IUUC-Osa-085958	Oryza sativa	36.72	2.00e-112	399.00
IUUC-Ola-086968	Oryzias latipes	75.33	0.00e+00	964.00
IUUC-Oga-089108	Otolemur garnettii	88.01	0.00e+00	1129.00
IUUC-Oar-089986	Ovis aries	84.10	0.00e+00	1053.00
IUUC-Ptr-091281	Pan troglodytes	89.00	0.00e+00	1105.00
IUUC-Pan-092585	Papio anubis	88.58	0.00e+00	1087.00
IUUC-Psi-093811	Pelodiscus sinensis	91.69	0.00e+00	1164.00
IUUC-Pma-094542	Petromyzon marinus	70.23	0.00e+00	904.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.34	3.00e-111	395.00
IUUC-Ppa-095876	Physcomitrella patens	36.47	2.00e-112	399.00
IUUC-Pfo-096973	Poecilia formosa	75.99	0.00e+00	1000.00
IUUC-Pab-098391	Pongo abelii	88.08	0.00e+00	1085.00
IUUC-Pop-098850	Populus trichocarpa	38.13	9.00e-116	410.00
IUUC-Pca-100257	Procavia capensis	56.57	3.00e-84	305.00
IUUC-Ppe-101578	Prunus persica	38.63	4.00e-116	411.00
IUUC-Pva-102872	Pteropus vampyrus	83.64	0.00e+00	1056.00
IUUC-Pgr-103593	Puccinia graminis	32.89	1.00e-80	293.00
IUUC-Pte-104365	Pyrenophora teres	38.83	1.00e-112	399.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.50	3.00e-115	408.00
IUUC-Rno-105737	Rattus norvegicus	88.74	0.00e+00	1134.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.38	2.00e-70	259.00
IUUC-Sha-107084	Sarcophilus harrisii	87.34	0.00e+00	982.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.50	1.00e-111	396.00
IUUC-Spo-108309	Schizosaccharomyces pombe	32.95	6.00e-95	341.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	36.50	2.00e-111	395.00
IUUC-Smo-109255	Selaginella moellendorffii	36.89	1.00e-104	373.00
IUUC-Sit-109962	Setaria italica	37.56	1.00e-114	406.00
IUUC-Sly-110897	Solanum lycopersicum	38.89	2.00e-117	415.00
IUUC-Stu-111971	Solanum tuberosum	38.40	6.00e-116	410.00
IUUC-Sar-113415	Sorex araneus	71.59	7.00e-108	384.00
IUUC-Sbi-114857	Sorghum bicolor	37.01	4.00e-112	398.00
IUUC-Sre-114900	Sporisorium reilianum	35.81	3.00e-93	335.00
IUUC-Tgu-117256	Taeniopygia guttata	96.35	0.00e+00	1212.00
IUUC-Tru-117871	Takifugu rubripes	71.36	0.00e+00	907.00
IUUC-Tsy-119172	Tarsius syrichta	92.50	9.00e-134	469.00
IUUC-Tni-120339	Tetraodon nigroviridis	71.69	0.00e+00	937.00
IUUC-Tca-121609	Theobroma cacao	37.85	6.00e-114	404.00
IUUC-Tre-122076	Trichoderma reesei	36.12	1.00e-98	353.00
IUUC-Tvi-122528	Trichoderma virens	34.75	8.00e-100	357.00
IUUC-Tae-124549	Triticum aestivum	35.84	7.00e-111	394.00
IUUC-Tur-126845	Triticum urartu	35.58	3.00e-83	302.00
IUUC-Tme-127217	Tuber melanosporum	35.47	6.00e-105	374.00
IUUC-Tbe-127526	Tupaia belangeri	86.40	0.00e+00	1078.00
IUUC-Ttr-128898	Tursiops truncatus	80.83	0.00e+00	1020.00
IUUC-Uma-129631	Ustilago maydis	33.83	3.00e-95	342.00
IUUC-Vda-129732	Verticillium dahliae	35.57	1.00e-95	343.00
IUUC-Vvi-131217	Vitis vinifera	38.03	7.00e-114	404.00
IUUC-Xtr-132860	Xenopus tropicalis	73.98	0.00e+00	949.00
IUUC-Xma-133830	Xiphophorus maculatus	75.99	0.00e+00	999.00
IUUC-Yli-134335	Yarrowia lipolytica	33.01	1.00e-73	270.00
IUUC-Zma-135907	Zea mays	37.17	7.00e-113	400.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence