iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033749

Ensembl Protein ID

ENSECAP00000021467.1

UniProt Accession

F6YZI7; F6YZI7_HORSE

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000023961.1	ENSECAT00000025786.1	ENSECAP00000021467.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	92.25	0.00e+00	729.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MDRSKENCIS GPVKTTVPLG DGPKRVPVTQ QLPQNLLSAN SGQAQRVLCP SNSSHRVPSQ 60
AQKLVSSHKP VQNLKQKQSQ ATSVPHPVPR PLNNTQRSEQ LQPSAPGNNS EKELASKEKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGAT CTAAAGAAAA CTGCATTTCA GGGCCTGTTA AGGTAAATTG AATAATCTGT 60
AATCTCAATC ACATTTATAA AAGCCAAGTG GAGATTGGTC TCATATCTGG AATTCTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

ecb:100050161

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	62.24	2.00e-103	368.00
IUUC-Aml-001426	Ailuropoda melanoleuca	94.57	0.00e+00	755.00
IUUC-Atr-002453	Amborella trichopoda	67.04	4.00e-107	380.00
IUUC-Apl-003626	Anas platyrhynchos	69.85	7.00e-157	546.00
IUUC-Aca-004602	Anolis carolinensis	69.37	2.00e-148	518.00
IUUC-Aly-005878	Arabidopsis lyrata	64.68	5.00e-105	373.00
IUUC-Ath-007117	Arabidopsis thaliana	65.43	1.00e-105	375.00
IUUC-Acl-008199	Aspergillus clavatus	56.88	2.00e-89	322.00
IUUC-Afl-008419	Aspergillus flavus	56.00	2.00e-87	315.00
IUUC-Afu-008751	Aspergillus fumigatus	51.27	4.00e-88	318.00
IUUC-Ani-009181	Aspergillus nidulans	51.27	3.00e-91	328.00
IUUC-Ang-009787	Aspergillus niger	51.12	2.00e-87	315.00
IUUC-Aor-009980	Aspergillus oryzae	56.00	2.00e-87	315.00
IUUC-Ate-010286	Aspergillus terreus	54.01	2.00e-87	315.00
IUUC-Ame-010849	Astyanax mexicanus	59.55	3.00e-128	451.00
IUUC-Bgr-012110	Blumeria graminis	58.30	2.00e-88	319.00
IUUC-Bta-013474	Bos taurus	90.35	0.00e+00	735.00
IUUC-Bci-013756	Botrytis cinerea	58.30	1.00e-94	339.00
IUUC-Bdi-014257	Brachypodium distachyon	62.94	7.00e-105	373.00
IUUC-Bol-016310	Brassica oleracea	63.50	5.00e-103	367.00
IUUC-Bra-017438	Brassica rapa	63.50	2.00e-104	371.00
IUUC-Cel-018157	Caenorhabditis elegans	62.50	4.00e-101	360.00
IUUC-Cja-019282	Callithrix jacchus	90.59	0.00e+00	714.00
IUUC-Cfa-020162	Canis familiaris	91.83	0.00e+00	744.00
IUUC-Cpo-021764	Cavia porcellus	83.46	0.00e+00	679.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.92	3.00e-107	380.00
IUUC-Csa-023694	Chlorocebus sabaeus	90.10	0.00e+00	667.00
IUUC-Cho-024350	Choloepus hoffmanni	94.84	3.00e-113	400.00
IUUC-Cin-025542	Ciona intestinalis	70.80	2.00e-117	415.00
IUUC-Csv-025873	Ciona savignyi	67.94	1.00e-117	416.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	47.90	8.00e-81	293.00
IUUC-Cne-026928	Cryptococcus neoformans	58.97	7.00e-95	340.00
IUUC-Cme-027336	Cyanidioschyzon merolae	72.73	4.00e-119	421.00
IUUC-Dre-028198	Danio rerio	62.30	4.00e-131	461.00
IUUC-Dno-029928	Dasypus novemcinctus	89.15	0.00e+00	668.00
IUUC-Dor-030238	Dipodomys ordii	79.65	0.00e+00	649.00
IUUC-Dse-031266	Dothistroma septosporum	54.79	5.00e-93	334.00
IUUC-Dme-032007	Drosophila melanogaster	61.45	4.00e-100	358.00
IUUC-Ete-032911	Echinops telfairi	67.98	8.00e-135	473.00
IUUC-Eeu-035170	Erinaceus europaeus	88.40	0.00e+00	721.00
IUUC-Fca-035498	Felis catus	94.36	0.00e+00	758.00
IUUC-Fal-037397	Ficedula albicollis	64.90	1.00e-152	532.00
IUUC-Fox-037747	Fusarium oxysporum	51.03	8.00e-91	327.00
IUUC-Fso-038429	Fusarium solani	55.90	8.00e-90	323.00
IUUC-Gmo-039378	Gadus morhua	60.26	1.00e-125	442.00
IUUC-Ggr-039939	Gaeumannomyces graminis	58.01	9.00e-95	340.00
IUUC-Gga-040187	Gallus gallus	70.42	8.00e-154	536.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.05	9.00e-133	466.00
IUUC-Gma-042870	Glycine max	63.38	3.00e-99	354.00
IUUC-Ggo-045617	Gorilla gorilla	91.34	0.00e+00	747.00
IUUC-Hsa-046968	Homo sapiens	91.58	0.00e+00	749.00
IUUC-Hvu-047072	Hordeum vulgare	53.99	1.00e-81	296.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	77.42	4.00e-178	617.00
IUUC-Kpa-049093	Komagataella pastoris	55.94	8.00e-77	280.00
IUUC-Lch-050346	Latimeria chalumnae	66.92	2.00e-148	518.00
IUUC-Lpe-051466	Leersia perrieri	66.79	2.00e-105	375.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	5.00e-89	321.00
IUUC-Laf-053422	Loxodonta africana	87.13	0.00e+00	713.00
IUUC-Mcc-055245	Macaca mulatta	90.63	0.00e+00	661.00
IUUC-Mor-056952	Magnaporthe oryzae	54.73	3.00e-91	328.00
IUUC-Mpo-057605	Magnaporthe poae	56.31	4.00e-96	344.00
IUUC-Mtr-057726	Medicago truncatula	63.86	1.00e-105	375.00
IUUC-Mla-059174	Melampsora laricipopulina	63.32	2.00e-98	352.00
IUUC-Mga-059562	Meleagris gallopavo	60.10	1.00e-119	422.00
IUUC-Mvi-060305	Microbotryum violaceum	58.97	6.00e-94	337.00
IUUC-Mmr-061588	Microcebus murinus	88.09	0.00e+00	733.00
IUUC-Mdo-061914	Monodelphis domestica	79.12	2.00e-178	618.00
IUUC-Mmu-063288	Mus musculus	83.37	0.00e+00	665.00
IUUC-Mac-064969	Musa acuminata	64.56	6.00e-106	376.00
IUUC-Mpu-066855	Mustela putorius furo	92.51	0.00e+00	742.00
IUUC-Mlu-068046	Myotis lucifugus	90.70	0.00e+00	716.00
IUUC-Nfi-068527	Neosartorya fischeri	56.73	1.00e-87	316.00
IUUC-Ncr-068678	Neurospora crassa	57.80	4.00e-93	335.00
IUUC-Nle-069848	Nomascus leucogenys	91.09	0.00e+00	744.00
IUUC-Opr-070589	Ochotona princeps	80.89	0.00e+00	640.00
IUUC-Ont-071733	Oreochromis niloticus	61.42	7.00e-125	440.00
IUUC-Oan-073399	Ornithorhynchus anatinus	88.70	7.00e-155	539.00
IUUC-Ocu-074063	Oryctolagus cuniculus	86.39	0.00e+00	709.00
IUUC-Oba-075264	Oryza barthii	63.38	1.00e-104	372.00
IUUC-Obr-076048	Oryza brachyantha	65.54	4.00e-104	370.00
IUUC-Ogl-077637	Oryza glaberrima	66.42	3.00e-104	371.00
IUUC-Ogu-078830	Oryza glumaepatula	63.38	7.00e-105	373.00
IUUC-Oin-079150	Oryza indica	63.38	6.00e-105	373.00
IUUC-Olo-080398	Oryza longistaminata	58.09	5.00e-83	300.00
IUUC-Ome-081544	Oryza meridionalis	55.51	6.00e-91	327.00
IUUC-Oni-082250	Oryza nivara	63.38	6.00e-105	373.00
IUUC-Opu-083638	Oryza punctata	63.99	2.00e-105	374.00
IUUC-Oru-084981	Oryza rufipogon	63.38	5.00e-105	373.00
IUUC-Osa-085961	Oryza sativa	63.38	5.00e-105	373.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.96	3.00e-112	397.00
IUUC-Oga-088891	Otolemur garnettii	88.86	0.00e+00	711.00
IUUC-Oar-090021	Ovis aries	90.10	0.00e+00	714.00
IUUC-Ptr-091458	Pan troglodytes	91.83	0.00e+00	750.00
IUUC-Pan-092546	Papio anubis	89.85	0.00e+00	665.00
IUUC-Psi-093280	Pelodiscus sinensis	75.53	6.00e-166	576.00
IUUC-Pma-094298	Petromyzon marinus	76.60	9.00e-121	426.00
IUUC-Pno-094847	Phaeosphaeria nodorum	57.95	1.00e-89	323.00
IUUC-Ppa-095855	Physcomitrella patens	62.50	3.00e-108	384.00
IUUC-Pfo-096428	Poecilia formosa	60.15	1.00e-128	452.00
IUUC-Pab-098696	Pongo abelii	91.11	0.00e+00	731.00
IUUC-Pop-099405	Populus trichocarpa	64.52	9.00e-106	376.00
IUUC-Pca-100740	Procavia capensis	81.19	0.00e+00	670.00
IUUC-Ppe-101854	Prunus persica	63.29	3.00e-106	377.00
IUUC-Pva-103212	Pteropus vampyrus	91.19	0.00e+00	723.00
IUUC-Pgr-103474	Puccinia graminis	63.26	2.00e-98	352.00
IUUC-Ptt-103933	Puccinia triticina	45.36	3.00e-62	231.00
IUUC-Pte-104089	Pyrenophora teres	56.89	6.00e-89	320.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	56.89	5.00e-89	321.00
IUUC-Rno-105057	Rattus norvegicus	83.37	0.00e+00	664.00
IUUC-Sha-107137	Sarcophilus harrisii	80.62	0.00e+00	627.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	60.66	2.00e-99	355.00
IUUC-Spo-108078	Schizosaccharomyces pombe	62.32	9.00e-104	369.00
IUUC-Smo-109288	Selaginella moellendorffii	67.04	5.00e-108	383.00
IUUC-Sit-110246	Setaria italica	65.22	5.00e-105	373.00
IUUC-Sly-111379	Solanum lycopersicum	64.66	5.00e-107	380.00
IUUC-Stu-112777	Solanum tuberosum	61.54	5.00e-105	374.00
IUUC-Sbi-114325	Sorghum bicolor	64.86	7.00e-105	373.00
IUUC-Sre-115203	Sporisorium reilianum	58.80	5.00e-80	291.00
IUUC-Ssc-115361	Sus scrofa	91.85	0.00e+00	751.00
IUUC-Tgu-116967	Taeniopygia guttata	72.46	5.00e-150	523.00
IUUC-Tru-117570	Takifugu rubripes	63.01	2.00e-135	475.00
IUUC-Tsy-119280	Tarsius syrichta	68.56	2.00e-140	491.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.12	1.00e-134	472.00
IUUC-Tca-121494	Theobroma cacao	64.29	5.00e-105	373.00
IUUC-Tre-121869	Trichoderma reesei	55.05	2.00e-94	339.00
IUUC-Tvi-122510	Trichoderma virens	58.87	4.00e-92	331.00
IUUC-Tae-123071	Triticum aestivum	62.24	2.00e-103	368.00
IUUC-Tur-126240	Triticum urartu	62.24	6.00e-103	366.00
IUUC-Tme-126921	Tuber melanosporum	59.93	2.00e-96	345.00
IUUC-Tbe-127872	Tupaia belangeri	83.63	0.00e+00	643.00
IUUC-Ttr-129134	Tursiops truncatus	91.47	0.00e+00	698.00
IUUC-Uma-129412	Ustilago maydis	57.89	6.00e-79	288.00
IUUC-Vda-130003	Verticillium dahliae	58.24	9.00e-92	330.00
IUUC-Vvi-131272	Vitis vinifera	65.92	2.00e-105	375.00
IUUC-Xtr-132019	Xenopus tropicalis	65.67	3.00e-150	524.00
IUUC-Xma-134203	Xiphophorus maculatus	60.30	1.00e-132	466.00
IUUC-Yli-134503	Yarrowia lipolytica	54.23	2.00e-86	312.00
IUUC-Zma-135232	Zea mays	65.09	8.00e-105	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence