iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-110991

Ensembl Protein ID

Solyc04g008720.2.1

UniProt Accession

K4BP28; K4BP28_SOLLC

Protein Name

Katanin p80 WD40 repeat-containing subunit B1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc04g008720.2	Solyc04g008720.2.1	Solyc04g008720.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-35	118.5	142	180
UBD/Beta-Prp	3.30e-57	194.7	15	252

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt +v+ ++f +d + +vsG+ D ++k+WDl+ g+ll+
   Q: 142  GHTRGVNTIRFtPDgRWVVSGGEDRSVKIWDLTAGKLLH 180
           8***********99999******************9986 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           +h+  ++c+k+  +++++l+tg++d+++ +w++ +++++ slsgh++++ +v+f++++ + + g+  +tik+wdl+  k+v+tl+gh ++ 
   Q: 15   AHSLSVNCLKIgRKSSRVLVTGGEDHKVNLWSIGKPDAILSLSGHSSGIDSVSFDSSEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRSNC 105
           7899999****99*********************************************999999999************************ PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
            sl+f+p g++++sGs d  +++wd++ + c++ t +gh++ vn++++ pdg+ +vsG+ Dr v++Wdl  gkll++++  h++++++++f
   Q: 106  ISLDFHPFGEFFASGSLDTNLKIWDIRRKGCIH-TYKGHTRGVNTIRFTPDGRWVVSGGEDRSVKIWDLTAGKLLHDFKC-HEGKIQCIDF 194
           *********************************.********************************************98.********** PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           ++  + l++gs d+tvk+wdl++ e + +    t+ v+s++f  ++  l++g +++ ++
   Q: 195  HPHEFLLATGSADKTVKFWDLESFELIGSAGPETTGVRSMAFNTDGRTLLCGLHEN-LK 252
           *******************************************9999999997554.33 PP

Organism

Solanum lycopersicum

Functional Description
(View)

May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.

Protein Sequence
(Fasta)

MTTTKRAYKL QEFVAHSLSV NCLKIGRKSS RVLVTGGEDH KVNLWSIGKP DAILSLSGHS 60
SGIDSVSFDS SEVLVAAGAA SGTIKLWDLE EAKIVRTLTG HRSNCISLDF HPFGEFFASG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAACTA CCAAACGTGC TTATAAGCTA CGTATCCTAT TTTTTTTTTT GGTTTGTATT 60
GTTAGTTTAT TTGCTTAATT TTGTTGTTTG GCTTGCAATT GGTCATATAG GGTAACAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0051013--P:microtubule severing

KEGG

sly:101249258

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bgr-012225	Blumeria graminis	30.00	1.00e-29	124.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	43.91	4.00e-82	298.00
IUUC-Ogu-078062	Oryza glumaepatula	41.39	3.00e-164	571.00
IUUC-Osa-085801	Oryza sativa	42.54	5.00e-176	610.00
IUUC-Stu-112053	Solanum tuberosum	96.79	0.00e+00	1557.00
IUUC-Sbi-114389	Sorghum bicolor	38.23	9.00e-161	560.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence