iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-001031

Ensembl Protein ID

EMT32744

UniProt Accession

M8CEC8; M8CEC8_AEGTA

Genbank Protein ID

EMT32744.1

Protein Name

Cullin-3

Genbank Nucleotide ID

KD501372

Gene Name

F775_29004

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_29004	EMT32744	EMT32744

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.40e-207	692.0	1	573

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 29   lclskvgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllel 127
           ++l+k+g+klY+ l+ +++  +k+++k++e++++  +L+ +n +W +++++l+++r+i++y+drtyv   ++ ++v++L+l+lwr++i+++  i+ rll++
   Q: 1    MVLHKYGEKLYNGLESTMTWRLKEISKSIEAAQGGLFLEELNAKWMDHNKALQMIRDILMYMDRTYVPT-SHRTPVHELGLNLWRDHIIHYpmIHGRLLDT 100
           799******************************************************************.999**************************** PP
   S: 128  llklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevve 228
           ll+li++eR ge+++r l++++ ++l++L+    a+y+++FE++fle ++ fy+ es+ef++ +++ +Ylkk+e rlnee er+++yl++ +e k+++vve
   Q: 101  LLDLIHRERMGEVINRGLMRSITKMLMDLG---PAVYQDDFEKPFLEVSASFYSGESQEFIECCDCGNYLKKAERRLNEEMERVSHYLDAGSEAKITSVVE 198
           *****************************9...9******************************************************************* PP
   S: 229  keliakhlesll....aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakF 325
           ke+ia+h+++l+    ++lv++l d+k+edl+rmy L++rv++gl+++++ ++s+++e gk+++t++e+ kdp+++V+ ll+ k+k +k+++ aF+nd++F
   Q: 199  KEMIANHMHRLVhmenSGLVNMLIDDKYEDLGRMYTLFRRVPDGLSTIRDMMTSYLRETGKHLVTDPERLKDPVEFVQCLLNEKDKHDKIINVAFGNDKTF 299
           ***********999999************************************************************************************ PP
   S: 326  lkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeec 426
           ++al+++fe f+n n      +spE+++ y+D++Lrk++kg+tee++e +ldkv+++f+y++ekdvFekyYk+hLakRLlsgk++s++aE+s+i kLk+ec
   Q: 300  QNALNSSFEFFINLN-----NRSPEFISLYVDDKLRKGLKGATEEDVEGILDKVMMLFRYLQEKDVFEKYYKQHLAKRLLSGKTVSDDAERSMIVKLKTEC 395
           ***************.....9******************************************************************************** PP
   S: 427  gaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelk 527
           g++ftskLe+Mf+d+k+S+d++++F+  k+++e   +++l v +L++g+Wpt+++ + +sLP+e+ + +ekf+ +Yl +hsgR+L+Wq+++g+a++ka++ 
   Q: 396  GYQFTSKLEGMFTDMKTSQDTMQDFY-AKKSEELGDGPTLDVHILTTGSWPTQPSPP-CSLPPEILAVCEKFRGYYLGTHSGRRLTWQTNMGTADIKATFG 494
           **************************.6666678999****************9866.******************************************8 PP
   S: 528  kg.kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk.kqvlkkepeskeieeedlfsvNqef 604
           k  k+el+Vst+Qm+vL++fn+s+ +s++++++ate+p  +L+r+lqsL+++k k+vl+kep+sk+i+e+d+f++N++f
   Q: 495  KSqKHELNVSTYQMCVLMLFNTSDGLSYKDIEQATEIPSTDLKRCLQSLACVKgKNVLRKEPMSKDISEDDTFYFNDKF 573
           8779*************************************************************************99 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MVLHKYGEKL YNGLESTMTW RLKEISKSIE AAQGGLFLEE LNAKWMDHNK ALQMIRDILM 60
YMDRTYVPTS HRTPVHELGL NLWRDHIIHY PMIHGRLLDT LLDLIHRERM GEVINRGLMR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGCTTC ACAAGTATGG CGAGAAGCTC TATAATGGCC TTGAGAGCAC TATGACATGG 60
CGTTTGAAGG AAATATCAAA ATCAATAGAG GCTGCACAGG GTGGTTTGTT TTTGGAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_29004

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002616	Amborella trichopoda	82.92	0.00e+00	1120.00
IUUC-Aly-005566	Arabidopsis lyrata	77.90	0.00e+00	1060.00
IUUC-Ath-007587	Arabidopsis thaliana	78.37	0.00e+00	1066.00
IUUC-Bdi-014269	Brachypodium distachyon	94.84	0.00e+00	1246.00
IUUC-Cin-025201	Ciona intestinalis	48.46	2.00e-164	571.00
IUUC-Ete-032347	Echinops telfairi	44.82	5.00e-141	494.00
IUUC-Gma-043659	Glycine max	78.53	0.00e+00	1060.00
IUUC-Hvu-047831	Hordeum vulgare	97.97	0.00e+00	1281.00
IUUC-Lpe-051396	Leersia perrieri	92.02	0.00e+00	1237.00
IUUC-Opr-070333	Ochotona princeps	52.69	4.00e-148	517.00
IUUC-Oba-075332	Oryza barthii	92.96	0.00e+00	1244.00
IUUC-Obr-076435	Oryza brachyantha	92.95	0.00e+00	1249.00
IUUC-Ogl-077655	Oryza glaberrima	92.96	0.00e+00	1249.00
IUUC-Ogu-078458	Oryza glumaepatula	92.96	0.00e+00	1245.00
IUUC-Oin-079567	Oryza indica	92.96	0.00e+00	1250.00
IUUC-Olo-080930	Oryza longistaminata	93.11	0.00e+00	1251.00
IUUC-Ome-081353	Oryza meridionalis	92.96	0.00e+00	1248.00
IUUC-Oni-082378	Oryza nivara	92.96	0.00e+00	1249.00
IUUC-Opu-084055	Oryza punctata	92.80	0.00e+00	1249.00
IUUC-Oru-084202	Oryza rufipogon	92.80	0.00e+00	1244.00
IUUC-Osa-085290	Oryza sativa	92.80	0.00e+00	1248.00
IUUC-Pop-099206	Populus trichocarpa	83.07	0.00e+00	1123.00
IUUC-Sit-110763	Setaria italica	93.74	0.00e+00	1236.00
IUUC-Sar-113144	Sorex araneus	52.69	3.00e-148	518.00
IUUC-Sbi-114690	Sorghum bicolor	93.27	0.00e+00	1255.00
IUUC-Tca-121282	Theobroma cacao	81.35	0.00e+00	1124.00
IUUC-Tae-124292	Triticum aestivum	98.90	0.00e+00	1291.00
IUUC-Tur-126800	Triticum urartu	99.06	0.00e+00	1293.00
IUUC-Tbe-127427	Tupaia belangeri	46.74	1.00e-132	466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence