iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-109722

Ensembl Protein ID

Si034045m

UniProt Accession

K4A591; K4A591_SETIT

Genbank Protein ID

KQK91299.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CM003536

Gene Name

SETIT_034045mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si034045m.g	Si034045m	Si034045m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.70e-169	563.9	425	911

Active Site

Position(s)	Description	Evidence
606	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahee 95
           YD Qi ++G+  q+kl+ a+v++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+ qFLfr++++g+ K+ vaa a+  +n+  +++a ++
   Q: 425  YDAQISVFGSRLQKKLRDANVFVVGSGALGCEFLKNLALMGVscsrkGKLTITDDDVIEKSNLSSQFLFRDWNIGQAKSTVAATAASAINSCLHIDALQN 524
           **************************************************************************************************** PP
   S: 96   siteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           + ++++e+++   F + +dvV++aldn+ ar++++ +cl+ ++pl+esgtlG++ +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa  
   Q: 525  RACPETEHVFhdaFWEGLDVVINALDNVNARMYMDMRCLYFQKPLLESGTLGTKCNTQMVIPHLTENYGASQDPPEKQAPMCTVHSFPHNIDHCVTWArs 624
           ********9899999999********************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv...... 274
                       +n +l++ ++     +k   ++ +e +++v++ l++e+ e fe++i++a+ +f+ +++n +kql+  f+ d  t+ ++pfw+      
   Q: 625  efeglldktpNEVNSFLSNPTQYAAAMKKAGDAQARELLERVRECLEKERCERFEDCITWARLKFEDYFSNRVKQLTFTFPEDAATSTGAPFWSapkrfp 724
           *********9999999999999999999************************************************************************ PP
   S: 275  ...................................................sfcsna.ealqvpekvekdeevvkasap.lylllralerfekk..kgrk 319
                                                              +f++ +  +++++ek++    ++ ++a+ ++ ll++le  +kk  +g  
   Q: 725  rplefsttdlshvqfimaasilravsfgitvpdwaksttnlidaiskvyvpEFKPKSgVKIETDEKANNISSASVDDAAvIEDLLAKLEASAKKlpPGFR 824
           ************************************9999999999999995555442566677777777666666666877777777777776557899 PP
   S: 320  pgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfda 403
            + + fekddd   ++dl++ +an+ra ++gi++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  + e + n+f ++a
   Q: 825  LKPIHFEKDDDTnfHMDLIAGLANMRARNYGIQE-VDRLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLAGghPVEDYHNTFSNLA 911
           999*******************************.*************************************9999999****99877 PP

Organism

Setaria italica

Protein Sequence
(Fasta)

MVAGEEAGGG GGSGNMSGVA EIDEDLHSRQ LAVYGRETMR RLFASNVLIS GLNGLGAEIA 60
KNLALAGVKS VTLHDAGNVE MWDLSGNFFL SEDDIGKNRA VACAAKLQEL NNAVDISALT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCGCCCT CGAGCCTCGA GGCCGCGACC GCCGCGCGAA CCCTAGCCGC CGCTCCGATC 60
GCCCCCACCG GTAAAGCCGT AAGCTCCCTC GTCGACTCGA TTCGTTCCGA TGATTCGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

sita:101779341

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Hvu-047846	Hordeum vulgare	84.84	0.00e+00	1737.00
IUUC-Lpe-051520	Leersia perrieri	85.45	0.00e+00	1792.00
IUUC-Oba-075913	Oryza barthii	86.72	0.00e+00	1781.00
IUUC-Ogl-077371	Oryza glaberrima	86.72	0.00e+00	1781.00
IUUC-Ogu-078793	Oryza glumaepatula	86.72	0.00e+00	1781.00
IUUC-Oin-079710	Oryza indica	86.62	0.00e+00	1776.00
IUUC-Olo-080255	Oryza longistaminata	86.72	0.00e+00	1782.00
IUUC-Ome-081171	Oryza meridionalis	86.52	0.00e+00	1772.00
IUUC-Oni-082436	Oryza nivara	86.52	0.00e+00	1778.00
IUUC-Opu-083161	Oryza punctata	86.07	0.00e+00	1758.00
IUUC-Oru-085015	Oryza rufipogon	86.62	0.00e+00	1781.00
IUUC-Osa-085455	Oryza sativa	86.52	0.00e+00	1779.00
IUUC-Pma-094214	Petromyzon marinus	44.71	2.00e-34	137.00
IUUC-Sbi-114475	Sorghum bicolor	83.84	0.00e+00	1670.00
IUUC-Tae-125628	Triticum aestivum	85.33	0.00e+00	1756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence