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Tag Content
UUCD2 ID IUUC-Dre-028567
UUCD1 version UUC-DaR-01307
Ensembl Protein ID ENSDARP00000017792.3
UniProt Accession Q7ZV55; EIF3I_DANRE
Genbank Protein ID AAH45995.1; AAH65874.1
Protein Name Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36
Genbank Nucleotide ID BC045995; BC065874
Gene Name eif3i; eif3s2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000017445.5 ENSDART00000005119.4 ENSDARP00000017792.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.70e-19 68.6 50 87
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d + +++Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdvDW-DtKNVLTGSADNSCRLWDCETGKQL 87
           8*******63377.4488*****************9986 PP
   
Organism Danio rerio
Functional Description
(View)

Functional Description


     Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Protein Sequence
(Fasta)
MKPILLQGHE RSITQIKYNR EGDLLFSVAK DPIANVWYSV NGERLGTYNG HTGAVWCVDV 60
DWDTKNVLTG SADNSCRLWD CETGKQLALL ETSSAVRTCG FDFSGNIIMF STDKQMGYQC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028567|E3,WD_repeat|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAACACGGA CCCATTTTCC TCCGTACAGG AAATGAAGTC CGTCTTTTCC GTTGGTAACC 60
GGGCGCCGTT CAGCACGCGC ACAGCGTACT GTTTTCTTTC TAAGGCAGAT TGACGTGTAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028567|E3,WD_repeat|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001889--P:liver development
GO:0002040--P:sprouting angiogenesis
GO:0006413--P:translational initiation
KEGG dre:406263
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000115 Aegilops tauschii 56.64 2.00e-34 140.00
IUUC-Aml-001321 Ailuropoda melanoleuca 83.64 4.00e-170 590.00
IUUC-Atr-002468 Amborella trichopoda 50.00 2.00e-53 201.00
IUUC-Apl-003841 Anas platyrhynchos 85.49 1.00e-174 605.00
IUUC-Aca-005123 Anolis carolinensis 85.23 2.00e-174 605.00
IUUC-Aly-006532 Arabidopsis lyrata 45.73 6.00e-86 310.00
IUUC-Ath-007094 Arabidopsis thaliana 45.73 2.00e-88 319.00
IUUC-Ago-008000 Ashbya gossypii 42.90 6.00e-82 297.00
IUUC-Acl-008098 Aspergillus clavatus 50.90 4.00e-98 351.00
IUUC-Afl-008494 Aspergillus flavus 51.36 5.00e-99 354.00
IUUC-Afu-009080 Aspergillus fumigatus 51.20 6.00e-99 353.00
IUUC-Ani-009230 Aspergillus nidulans 51.52 2.00e-98 352.00
IUUC-Aor-010114 Aspergillus oryzae 51.36 5.00e-99 354.00
IUUC-Ate-010285 Aspergillus terreus 53.05 1.00e-101 363.00
IUUC-Ame-011534 Astyanax mexicanus 91.13 0.00e+00 643.00
IUUC-Bgr-012121 Blumeria graminis 47.42 7.00e-88 317.00
IUUC-Bta-013143 Bos taurus 83.69 1.00e-170 592.00
IUUC-Bci-013950 Botrytis cinerea 50.46 9.00e-97 346.00
IUUC-Bdi-015019 Brachypodium distachyon 46.63 4.00e-89 321.00
IUUC-Bol-015709 Brassica oleracea 44.85 8.00e-84 305.00
IUUC-Bra-017760 Brassica rapa 44.85 3.00e-84 306.00
IUUC-Cel-018226 Caenorhabditis elegans 43.03 4.00e-81 294.00
IUUC-Cja-019741 Callithrix jacchus 83.69 3.00e-171 593.00
IUUC-Cfa-021204 Canis familiaris 83.33 7.00e-170 589.00
IUUC-Cpo-021661 Cavia porcellus 83.33 7.00e-170 589.00
IUUC-Cre-022952 Chlamydomonas reinhardtii 44.51 5.00e-83 300.00
IUUC-Csa-024038 Chlorocebus sabaeus 83.69 3.00e-171 593.00
IUUC-Cin-025597 Ciona intestinalis 58.77 8.00e-118 416.00
IUUC-Cgl-026583 Colletotrichum gloeosporioides 49.70 7.00e-93 333.00
IUUC-Cne-026838 Cryptococcus neoformans 47.71 2.00e-91 329.00
IUUC-Cme-027304 Cyanidioschyzon merolae 44.24 2.00e-81 295.00
IUUC-Dno-029171 Dasypus novemcinctus 83.33 2.00e-169 588.00
IUUC-Dor-030257 Dipodomys ordii 72.73 1.00e-75 276.00
IUUC-Dse-031191 Dothistroma septosporum 49.54 1.00e-92 333.00
IUUC-Dme-031879 Drosophila melanogaster 60.56 6.00e-120 423.00
IUUC-Ete-032336 Echinops telfairi 78.04 1.00e-103 368.00
IUUC-Eca-033259 Equus caballus 83.64 3.00e-170 590.00
IUUC-Eeu-035153 Erinaceus europaeus 61.74 2.00e-47 182.00
IUUC-Fca-036489 Felis catus 83.64 3.00e-170 590.00
IUUC-Fal-037485 Ficedula albicollis 85.49 7.00e-175 606.00
IUUC-Fox-037860 Fusarium oxysporum 48.32 3.00e-92 331.00
IUUC-Fso-038188 Fusarium solani 49.24 6.00e-92 330.00
IUUC-Gmo-039311 Gadus morhua 93.21 0.00e+00 649.00
IUUC-Ggr-040045 Gaeumannomyces graminis 50.15 7.00e-96 343.00
IUUC-Gga-040645 Gallus gallus 83.48 3.00e-173 600.00
IUUC-Gac-042086 Gasterosteus aculeatus 91.69 0.00e+00 637.00
IUUC-Gma-043246 Glycine max 45.09 2.00e-88 318.00
IUUC-Ggo-045578 Gorilla gorilla 83.69 3.00e-171 593.00
IUUC-Hsa-046734 Homo sapiens 83.69 3.00e-171 593.00
IUUC-Hvu-047553 Hordeum vulgare 46.01 1.00e-88 320.00
IUUC-Itr-048467 Ictidomys tridecemlineatus 83.33 6.00e-170 590.00
IUUC-Kpa-049325 Komagataella pastoris 43.87 4.00e-85 308.00
IUUC-Lch-049620 Latimeria chalumnae 84.56 4.00e-159 553.00
IUUC-Lpe-051338 Leersia perrieri 44.69 3.00e-81 295.00
IUUC-Loc-052094 Lepisosteus oculatus 83.90 1.00e-166 578.00
IUUC-Lma-053047 Leptosphaeria maculans 48.48 5.00e-93 334.00
IUUC-Laf-053801 Loxodonta africana 83.33 2.00e-166 578.00
IUUC-Mcc-055498 Macaca mulatta 72.92 1.00e-140 492.00
IUUC-Meu-056729 Macropus eugenii 76.69 5.00e-154 536.00
IUUC-Mor-057025 Magnaporthe oryzae 49.85 1.00e-92 332.00
IUUC-Mpo-057511 Magnaporthe poae 50.76 4.00e-95 341.00
IUUC-Mtr-058051 Medicago truncatula 46.32 8.00e-89 320.00
IUUC-Mla-059061 Melampsora laricipopulina 46.42 3.00e-84 305.00
IUUC-Mga-059229 Meleagris gallopavo 84.66 3.00e-172 597.00
IUUC-Mvi-060399 Microbotryum violaceum 45.48 4.00e-81 295.00
IUUC-Mmr-060764 Microcebus murinus 84.00 1.00e-171 595.00
IUUC-Mdo-062088 Monodelphis domestica 83.38 2.00e-170 591.00
IUUC-Mmu-064304 Mus musculus 84.00 4.00e-171 593.00
IUUC-Mac-065520 Musa acuminata 47.20 4.00e-90 324.00
IUUC-Mpu-066340 Mustela putorius furo 83.64 3.00e-170 590.00
IUUC-Mlu-067111 Myotis lucifugus 83.64 2.00e-170 591.00
IUUC-Nfi-068478 Neosartorya fischeri 51.20 1.00e-98 353.00
IUUC-Ncr-068820 Neurospora crassa 49.70 4.00e-93 334.00
IUUC-Nle-069903 Nomascus leucogenys 83.64 1.00e-170 592.00
IUUC-Opr-070221 Ochotona princeps 81.54 5.00e-165 573.00
IUUC-Ont-071765 Oreochromis niloticus 93.23 0.00e+00 649.00
IUUC-Oan-073660 Ornithorhynchus anatinus 81.97 1.00e-152 531.00
IUUC-Ocu-074039 Oryctolagus cuniculus 83.64 2.00e-170 591.00
IUUC-Oba-075395 Oryza barthii 39.26 4.00e-71 261.00
IUUC-Obr-076334 Oryza brachyantha 42.64 2.00e-80 292.00
IUUC-Ogl-077751 Oryza glaberrima 45.40 1.00e-87 316.00
IUUC-Ogu-078207 Oryza glumaepatula 45.54 2.00e-87 315.00
IUUC-Oin-079878 Oryza indica 45.71 6.00e-88 317.00
IUUC-Olo-080677 Oryza longistaminata 38.95 1.00e-78 286.00
IUUC-Ome-081228 Oryza meridionalis 33.74 4.00e-34 138.00
IUUC-Oni-082411 Oryza nivara 39.70 7.00e-71 260.00
IUUC-Opu-083136 Oryza punctata 45.40 3.00e-87 315.00
IUUC-Oru-084916 Oryza rufipogon 44.48 1.00e-85 309.00
IUUC-Osa-085454 Oryza sativa 45.71 6.00e-88 317.00
IUUC-Ola-087053 Oryzias latipes 91.69 0.00e+00 640.00
IUUC-Olu-087602 Ostreococcus lucimarinus 47.83 4.00e-89 321.00
IUUC-Oga-088154 Otolemur garnettii 83.33 1.00e-169 588.00
IUUC-Oar-089915 Ovis aries 83.64 4.00e-170 590.00
IUUC-Ptr-091124 Pan troglodytes 66.25 4.00e-125 441.00
IUUC-Pan-092035 Papio anubis 83.69 3.00e-171 593.00
IUUC-Psi-094096 Pelodiscus sinensis 80.18 5.00e-108 383.00
IUUC-Pno-094988 Phaeosphaeria nodorum 45.23 3.00e-82 298.00
IUUC-Ppa-095949 Physcomitrella patens 48.16 4.00e-93 334.00
IUUC-Pfo-096101 Poecilia formosa 92.00 0.00e+00 645.00
IUUC-Pab-097726 Pongo abelii 83.69 3.00e-171 593.00
IUUC-Pop-099617 Populus trichocarpa 46.63 2.00e-90 325.00
IUUC-Pca-101014 Procavia capensis 83.69 5.00e-171 593.00
IUUC-Ppe-101320 Prunus persica 46.01 4.00e-87 314.00
IUUC-Pva-102789 Pteropus vampyrus 74.15 4.00e-144 504.00
IUUC-Pgr-103479 Puccinia graminis 47.04 1.00e-84 306.00
IUUC-Ptt-103981 Puccinia triticina 47.35 5.00e-86 310.00
IUUC-Pte-104278 Pyrenophora teres 48.48 7.00e-91 327.00
IUUC-Pyt-104492 Pyrenophora triticirepentis 48.48 7.00e-91 327.00
IUUC-Rno-105867 Rattus norvegicus 66.06 2.00e-122 432.00
IUUC-Sce-106251 Saccharomyces cerevisiae 45.65 3.00e-83 301.00
IUUC-Sha-107039 Sarcophilus harrisii 83.38 1.00e-170 592.00
IUUC-Sja-107758 Schizosaccharomyces japonicus 50.76 3.00e-96 345.00
IUUC-Spo-108314 Schizosaccharomyces pombe 49.24 2.00e-93 335.00
IUUC-Ssl-108478 Sclerotinia sclerotiorum 49.85 8.00e-96 343.00
IUUC-Smo-108728 Selaginella moellendorffii 48.00 5.00e-88 317.00
IUUC-Sit-110801 Setaria italica 45.09 3.00e-86 311.00
IUUC-Sly-111326 Solanum lycopersicum 46.79 8.00e-89 320.00
IUUC-Stu-112458 Solanum tuberosum 46.63 4.00e-89 321.00
IUUC-Sbi-114063 Sorghum bicolor 44.48 4.00e-85 307.00
IUUC-Sre-115096 Sporisorium reilianum 46.87 1.00e-84 306.00
IUUC-Ssc-116080 Sus scrofa 83.69 8.00e-171 592.00
IUUC-Tgu-116988 Taeniopygia guttata 85.19 2.00e-174 604.00
IUUC-Tru-118766 Takifugu rubripes 92.31 0.00e+00 645.00
IUUC-Tni-120197 Tetraodon nigroviridis 91.69 0.00e+00 643.00
IUUC-Tca-121316 Theobroma cacao 45.40 8.00e-88 317.00
IUUC-Tre-122097 Trichoderma reesei 50.46 1.00e-93 336.00
IUUC-Tvi-122442 Trichoderma virens 50.46 3.00e-94 338.00
IUUC-Tae-125800 Triticum aestivum 46.01 1.00e-88 319.00
IUUC-Tur-126334 Triticum urartu 39.57 9.00e-69 253.00
IUUC-Tme-127038 Tuber melanosporum 51.22 7.00e-100 357.00
IUUC-Ttr-128659 Tursiops truncatus 78.15 2.00e-146 511.00
IUUC-Uma-129464 Ustilago maydis 47.16 1.00e-84 306.00
IUUC-Vda-129841 Verticillium dahliae 51.99 9.00e-97 346.00
IUUC-Vvi-131076 Vitis vinifera 46.18 4.00e-89 321.00
IUUC-Xtr-132395 Xenopus tropicalis 84.00 3.00e-174 604.00
IUUC-Xma-133383 Xiphophorus maculatus 92.31 0.00e+00 648.00
IUUC-Yli-134586 Yarrowia lipolytica 47.85 2.00e-81 295.00
IUUC-Zma-135667 Zea mays 44.79 1.00e-85 310.00
Created Date 25-Jun-2017

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