iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bdi-014102

UUCD1 version

UUC-BrD-01258

Ensembl Protein ID

BRADI1G51210.1

UniProt Accession

I1H1P8; I1H1P8_BRADI

Protein Name

Coatomer subunit beta'

Gene Name

LOC100823641

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BRADI1G51210	BRADI1G51210.1	BRADI1G51210.1
BRADI1G51210	BRADI1G51210.2	BRADI1G51210.2
BRADI1G51210	BRADI1G51210.3	BRADI1G51210.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-30	102.5	135	176
UBD/Beta-Prp	9.30e-58	196.3	3	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 135  GHQKGVNCVDYftgGDrPYLITGSDDSTAKVWDYQTKSCVQT 176
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvv 140
           +s++  e +v++ kf +++++ v g++D+ i+v++++t + v ++++h+d++++++++p+  +++s s+d  i++wd+++g+   ++++gh++ v
   Q: 3    KSFEVSELPVRSAKFVSRKQWVVAGADDMYIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTLPYVLSSSDDMLIKLWDWDKGWMCTQIFEGHSHYV 97
           678888999*************************************************************************9999********* PP
   S: 141  ncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfsp 232
           + v+++p++ n ++s+slDrt ++W+l + +   tl g h++ v++++     ++++l++gs+d+t k+wd+qt++cv+tl+ght n++ v f+p
   Q: 98   MQVTFNPKDtNTFASASLDRTTKIWSLGSPDPNFTLDG-HQKGVNCVDyfTGGDRPYLITGSDDSTAKVWDYQTKSCVQTLEGHTHNISAVCFHP 191
           *************************************9.*********7445566**************************************** PP
   S: 233  nderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvn 290
           +  ++++gs+Dg++riW +++  l +tl++  ++v++v +++   + +v g ++++++
   Q: 192  ELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVGYMKG-SRRMVIGYDEGTIM 248
           **************************************99444.45555555556655 PP

Organism

Brachypodium distachyon

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MVKSFEVSEL PVRSAKFVSR KQWVVAGADD MYIRVYNYNT MDKVKVFEAH TDYIRCVAVH 60
PTLPYVLSSS DDMLIKLWDW DKGWMCTQIF EGHSHYVMQV TFNPKDTNTF ASASLDRTTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAT CATTTGAAGT TTCAGAGTTG CCAGGTATTC AGCGCATTTG TGTTCACATG 60
AAGATAAAAT TTGTGCTAAA AGCTGTAACT GACTACTGTG TTATGTATGT TCGAATGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	89.68	0.00e+00	1523.00
IUUC-Mac-065544	Musa acuminata	84.06	0.00e+00	1491.00
IUUC-Oba-075760	Oryza barthii	94.54	0.00e+00	1618.00
IUUC-Ogl-077450	Oryza glaberrima	94.21	0.00e+00	1611.00
IUUC-Ogu-078994	Oryza glumaepatula	94.54	0.00e+00	1615.00
IUUC-Oin-079211	Oryza indica	94.49	0.00e+00	1598.00
IUUC-Olo-080731	Oryza longistaminata	94.55	0.00e+00	1621.00
IUUC-Ome-081762	Oryza meridionalis	88.56	0.00e+00	1500.00
IUUC-Oni-082324	Oryza nivara	94.54	0.00e+00	1617.00
IUUC-Opu-083433	Oryza punctata	94.37	0.00e+00	1598.00
IUUC-Oru-084829	Oryza rufipogon	94.44	0.00e+00	1618.00
IUUC-Osa-086026	Oryza sativa	94.49	0.00e+00	1599.00
IUUC-Pno-094785	Phaeosphaeria nodorum	59.11	3.00e-103	368.00
IUUC-Sit-110239	Setaria italica	94.32	0.00e+00	1672.00
IUUC-Stu-112906	Solanum tuberosum	80.38	0.00e+00	1414.00
IUUC-Sar-113472	Sorex araneus	56.06	0.00e+00	756.00
IUUC-Tae-125292	Triticum aestivum	94.90	0.00e+00	1667.00
IUUC-Tur-126283	Triticum urartu	88.44	0.00e+00	1519.00
IUUC-Vpa-130037	Vicugna pacos	48.55	9.00e-127	447.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence