iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058618

Ensembl Protein ID

KEH39574

UniProt Accession

A0A072VC11; A0A072VC11_MEDTR

Genbank Protein ID

KEH39574.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CM001218

Gene Name

MTR_2g102277

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_2g102277	KEH39574	KEH39574
MTR_2g102277	KEH39573	KEH39573

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-35	119.9	184	224
UBD/Beta-Prp	2.00e-67	228.9	14	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           ++++++cv+ +p +++++++ ++gt+ +w+++++++ +s++  e +v++ kf  ++++ v g++D++i+v++++t + v ++++h+d++++++++p+  ++
   Q: 14   RSERVKCVDLHPTEPWILASLYSGTVCIWNYQSQTMAKSFEVTELPVRSAKFVARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTLPYV 114
           67789************************************************************************************************ PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklw 207
           +s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     ++++l++gs+d t k+w
   Q: 115  LSSSDDMLIKLWDWEKGWICTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKPYLITGSDDHTAKVW 214
           ******************9999*********************************************98.*********6444555*************** PP
   S: 208  dlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
           d+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v+++ +l+ +++v++  
   Q: 215  DYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYLKSSRRVVIGY 290
           *****************************************************************99998888544 PP

Organism

Medicago truncatula

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKC VDLHPTEPWI LASLYSGTVC IWNYQSQTMA KSFEVTELPV 60
RSAKFVARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAGATCTA TCACACTCAC AACACGGATC TCCGTACCCA CAATAGTGTA CCCCACACAG 60
GAATACAGAT CCAGTGGCAT TTCCGTAATC TCACTTTAAC CAAATCTTTC ATAACACTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	73.56	0.00e+00	1405.00
IUUC-Atr-003090	Amborella trichopoda	81.08	0.00e+00	1541.00
IUUC-Aly-006508	Arabidopsis lyrata	87.22	0.00e+00	1642.00
IUUC-Ath-007635	Arabidopsis thaliana	86.49	0.00e+00	1632.00
IUUC-Bdi-015046	Brachypodium distachyon	81.16	0.00e+00	1557.00
IUUC-Bol-016271	Brassica oleracea	86.43	0.00e+00	1628.00
IUUC-Bra-017758	Brassica rapa	86.30	0.00e+00	1634.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	66.63	0.00e+00	1115.00
IUUC-Gma-044126	Glycine max	93.93	0.00e+00	1760.00
IUUC-Lpe-051579	Leersia perrieri	82.84	0.00e+00	1558.00
IUUC-Mac-064636	Musa acuminata	83.62	0.00e+00	1594.00
IUUC-Oba-075760	Oryza barthii	82.84	0.00e+00	1555.00
IUUC-Obr-076163	Oryza brachyantha	83.66	0.00e+00	1574.00
IUUC-Ogl-077450	Oryza glaberrima	83.73	0.00e+00	1580.00
IUUC-Ogu-078994	Oryza glumaepatula	82.84	0.00e+00	1552.00
IUUC-Oin-079211	Oryza indica	84.89	0.00e+00	1519.00
IUUC-Olo-080731	Oryza longistaminata	81.89	0.00e+00	1534.00
IUUC-Ome-081762	Oryza meridionalis	79.89	0.00e+00	1433.00
IUUC-Oni-082324	Oryza nivara	82.84	0.00e+00	1554.00
IUUC-Opu-083400	Oryza punctata	80.88	0.00e+00	1538.00
IUUC-Oru-084829	Oryza rufipogon	82.97	0.00e+00	1556.00
IUUC-Osa-086026	Oryza sativa	87.12	0.00e+00	1572.00
IUUC-Olu-087655	Ostreococcus lucimarinus	66.96	0.00e+00	1147.00
IUUC-Ppa-095911	Physcomitrella patens	79.35	0.00e+00	1434.00
IUUC-Pop-099634	Populus trichocarpa	88.82	0.00e+00	1652.00
IUUC-Ppe-101470	Prunus persica	90.80	0.00e+00	1717.00
IUUC-Sit-110239	Setaria italica	82.83	0.00e+00	1597.00
IUUC-Sly-111775	Solanum lycopersicum	84.85	0.00e+00	1629.00
IUUC-Stu-112906	Solanum tuberosum	85.60	0.00e+00	1486.00
IUUC-Sbi-113801	Sorghum bicolor	83.04	0.00e+00	1561.00
IUUC-Tca-121613	Theobroma cacao	91.31	0.00e+00	1739.00
IUUC-Tae-125488	Triticum aestivum	82.97	0.00e+00	1594.00
IUUC-Tur-126283	Triticum urartu	74.45	0.00e+00	1404.00
IUUC-Vvi-131689	Vitis vinifera	92.34	0.00e+00	1661.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence