iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d045379	Zm00001d045379_T005	Zm00001d045379_T005
Zm00001d045379	Zm00001d045379_T007	Zm00001d045379_T007
Zm00001d045379	Zm00001d045379_T002	Zm00001d045379_T002
Zm00001d045379	Zm00001d045379_T021	Zm00001d045379_T021
Zm00001d045379	Zm00001d045379_T024	Zm00001d045379_T024
Zm00001d045379	Zm00001d045379_T018	Zm00001d045379_T018
Zm00001d045379	Zm00001d045379_T006	Zm00001d045379_T006
Zm00001d045379	Zm00001d045379_T003	Zm00001d045379_T003

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-33	113.9	183	224
UBD/Beta-Prp	1.60e-67	229.8	10	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 183  GHQKGVNCVDYftgGDrPYLITGSDDSTAKVWDYQTKSCVQT 224
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
            ++++++++++v+ +p +++++++ ++g++ +wd++ + +++s++  e +v++ kf++++++ v g++D++i+v++++t + v ++++h+
   Q: 10   KFAQRSERVKSVDLHPTEPWILSSLYSGSVCIWDYQAQAMVKSFEVSELPVRSAKFISRKQWVVAGADDMFIRVYNYNTMDKVKVFEAHT 99
           567788999********************************************************************************* PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           d++++++++p+  +++s s+d  i++wd+++g++  ++++gh++ v+ v+++p++ n ++s+slDrt ++W+l + +   tl g h++ v
   Q: 100  DYIRCVAVHPTLPYVLSSSDDMLIKLWDWDKGWVCTQIFEGHSHYVMQVTFNPKDiNTFASASLDRTTKIWSLGSPDPNFTLDG-HQKGV 188
           *********************************9999**********************************************9.***** PP
   S: 184  ysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++     ++++l++gs+d+t k+wd+qt++cv+tl+ght n++ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v++v 
   Q: 189  NCVDyfTGGDRPYLITGSDDSTAKVWDYQTKSCVQTLEGHTHNISAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVG 278
           ****7445566******************************************************************************9 PP
   S: 272  vlsfgdnvlvlgsedskvn 290
           +++   + +v g ++++++
   Q: 279  YMKG-SRRMVIGYDEGTIM 296
           9444.45555555555655 PP

Organism

Zea mays

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK FAQRSERVKS VDLHPTEPWI LSSLYSGSVC IWDYQAQAMV KSFEVSELPV 60
RSAKFISRKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGCCACCG AGCCCGCGAT CGGATTCGCT CCCTCTTCGC CGCGCCCCAC CACCCATCGC 60
CGCTGGGGAT CCCTAGGGTT TAGTGCAGTC GCTCGGCTCC GCGCCGTCCT CGCCGCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	81.21	0.00e+00	1513.00
IUUC-Aly-006508	Arabidopsis lyrata	79.72	0.00e+00	1520.00
IUUC-Bdi-014102	Brachypodium distachyon	91.19	0.00e+00	1613.00
IUUC-Bra-016617	Brassica rapa	83.16	0.00e+00	1450.00
IUUC-Dme-031791	Drosophila melanogaster	57.16	0.00e+00	1014.00
IUUC-Eeu-035086	Erinaceus europaeus	48.79	6.00e-125	441.00
IUUC-Mvi-060240	Microbotryum violaceum	47.75	0.00e+00	882.00
IUUC-Oba-075760	Oryza barthii	90.74	0.00e+00	1663.00
IUUC-Ogl-077450	Oryza glaberrima	91.55	0.00e+00	1691.00
IUUC-Ogu-078994	Oryza glumaepatula	90.74	0.00e+00	1659.00
IUUC-Olo-080731	Oryza longistaminata	89.39	0.00e+00	1640.00
IUUC-Oni-082324	Oryza nivara	90.74	0.00e+00	1660.00
IUUC-Oru-084829	Oryza rufipogon	90.56	0.00e+00	1662.00
IUUC-Ppa-095911	Physcomitrella patens	74.92	0.00e+00	1395.00
IUUC-Smo-108695	Selaginella moellendorffii	79.78	0.00e+00	1385.00
IUUC-Sit-110239	Setaria italica	93.08	0.00e+00	1746.00
IUUC-Tae-125488	Triticum aestivum	90.86	0.00e+00	1700.00
IUUC-Tur-126283	Triticum urartu	81.97	0.00e+00	1516.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence