iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004726

Ensembl Protein ID

ENSACAP00000017237.2

UniProt Accession

G1KU18; G1KU18_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017506.2	ENSACAT00000017575.2	ENSACAP00000017237.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-24	85.3	149	179
UBD/Beta-Prp	2.20e-62	210.8	33	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************8 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
            +++ srd+t ++w  ++++     +r++sgh+++v++v+ +p ++     + +tg++D++i+++ l+++ ++++lkgh+++v+sls+ 
   Q: 33   AFVSVSRDRTARLWAPDSPNRgfaeMRCMSGHSNFVSSVCVIPPSDlyprgLVATGGNDNNICIFTLDNSAPLYVLKGHKNTVCSLSSG 121
           488999**************999*********************9999999************************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng 192
           +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g++ +t+tg h+d v+ l++ s+ 
   Q: 122  K-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGRCEKTFTG-HEDCVRGLAILSE- 202
           9.9***************..9******.*********************************..88********9.*********9998. PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlv 281
            e++s+++d +++ w++ +gec++ + ght+ ++++ ++p+++ +v++++D+s+riW  r+g++++t+ l+++sv++++v  +++  +v
   Q: 203  LEFLSCANDASIRRWQI-SGECLQVYYGHTNYIYCISVFPHSKDFVTTGEDRSLRIW--RQGECTQTIRLPAQSVWCCCV--LDNGDIV 286
           59***************.999************************************..9********************..9999*** PP
   S: 282  lgsedskvniwk 293
            g++d++++++ 
   Q: 287  VGASDGIIRVFT 298
           **********97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAGAGSAFRL RCSLAGHELD VRGLSGALFP AGAFVSVSRD RTARLWAPDS PNRGFAEMRC 60
MSGHSNFVSS VCVIPPSDLY PRGLVATGGN DNNICIFTLD NSAPLYVLKG HKNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGTG CGGGGAGCGC TTTCCGGCTC CGCTGCTCAC TGGCGGGCCA TGAGCTGGAC 60
GTGCGCGGCC TCAGCGGCGC CCTCTTCCCA GCCGGGGCCT TCGTGTCAGT GTCCCGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

KEGG

acs:100558394

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.30	5.00e-85	308.00
IUUC-Aml-002125	Ailuropoda melanoleuca	80.85	0.00e+00	1341.00
IUUC-Atr-002554	Amborella trichopoda	31.16	2.00e-95	343.00
IUUC-Apl-004094	Anas platyrhynchos	82.89	0.00e+00	1278.00
IUUC-Aly-005961	Arabidopsis lyrata	33.79	4.00e-106	378.00
IUUC-Ath-006639	Arabidopsis thaliana	33.60	6.00e-101	361.00
IUUC-Ago-007772	Ashbya gossypii	30.61	1.00e-84	307.00
IUUC-Acl-008316	Aspergillus clavatus	32.02	5.00e-86	311.00
IUUC-Afl-008532	Aspergillus flavus	34.26	3.00e-95	342.00
IUUC-Afu-008950	Aspergillus fumigatus	33.33	3.00e-92	332.00
IUUC-Ani-009186	Aspergillus nidulans	34.10	3.00e-96	346.00
IUUC-Ang-009575	Aspergillus niger	33.00	2.00e-91	330.00
IUUC-Aor-010086	Aspergillus oryzae	34.26	3.00e-95	342.00
IUUC-Ate-010541	Aspergillus terreus	31.84	1.00e-86	313.00
IUUC-Ame-011633	Astyanax mexicanus	65.20	0.00e+00	1096.00
IUUC-Bgr-012292	Blumeria graminis	30.94	3.00e-93	336.00
IUUC-Bta-013218	Bos taurus	80.03	0.00e+00	1335.00
IUUC-Bci-013876	Botrytis cinerea	33.25	7.00e-97	348.00
IUUC-Bdi-014810	Brachypodium distachyon	32.17	6.00e-99	355.00
IUUC-Bol-016006	Brassica oleracea	33.20	6.00e-104	371.00
IUUC-Bra-017593	Brassica rapa	34.39	7.00e-107	381.00
IUUC-Cel-018703	Caenorhabditis elegans	27.86	2.00e-73	270.00
IUUC-Cja-019270	Callithrix jacchus	79.75	0.00e+00	1330.00
IUUC-Cfa-021262	Canis familiaris	80.50	0.00e+00	1333.00
IUUC-Cpo-021449	Cavia porcellus	75.69	0.00e+00	1220.00
IUUC-Csa-024140	Chlorocebus sabaeus	80.50	0.00e+00	1340.00
IUUC-Cho-024923	Choloepus hoffmanni	75.57	4.00e-177	614.00
IUUC-Cin-025373	Ciona intestinalis	39.58	3.00e-169	588.00
IUUC-Csv-026324	Ciona savignyi	41.02	2.00e-180	625.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	30.91	9.00e-87	314.00
IUUC-Cne-026998	Cryptococcus neoformans	29.63	7.00e-85	308.00
IUUC-Cme-027154	Cyanidioschyzon merolae	31.51	3.00e-58	219.00
IUUC-Dre-028674	Danio rerio	65.17	0.00e+00	1087.00
IUUC-Dno-028966	Dasypus novemcinctus	80.13	0.00e+00	1342.00
IUUC-Dor-030343	Dipodomys ordii	73.07	0.00e+00	748.00
IUUC-Dse-031385	Dothistroma septosporum	31.97	4.00e-86	312.00
IUUC-Dme-032044	Drosophila melanogaster	36.48	4.00e-124	438.00
IUUC-Ete-032506	Echinops telfairi	72.13	0.00e+00	692.00
IUUC-Eca-033547	Equus caballus	80.90	0.00e+00	1346.00
IUUC-Eeu-034462	Erinaceus europaeus	66.37	3.00e-161	561.00
IUUC-Fca-035893	Felis catus	80.78	0.00e+00	1342.00
IUUC-Fal-037235	Ficedula albicollis	83.29	0.00e+00	1386.00
IUUC-Fox-037836	Fusarium oxysporum	31.72	2.00e-97	350.00
IUUC-Fso-038251	Fusarium solani	32.08	2.00e-96	346.00
IUUC-Gmo-038648	Gadus morhua	65.68	0.00e+00	957.00
IUUC-Ggr-039867	Gaeumannomyces graminis	29.64	1.00e-82	301.00
IUUC-Gga-040989	Gallus gallus	81.66	0.00e+00	1349.00
IUUC-Gac-041344	Gasterosteus aculeatus	67.17	0.00e+00	1054.00
IUUC-Gma-043067	Glycine max	32.24	1.00e-103	370.00
IUUC-Ggo-045009	Gorilla gorilla	80.30	0.00e+00	1028.00
IUUC-Hsa-046807	Homo sapiens	80.00	0.00e+00	1334.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	80.40	0.00e+00	1346.00
IUUC-Kpa-049134	Komagataella pastoris	34.99	2.00e-96	346.00
IUUC-Lch-049597	Latimeria chalumnae	73.00	0.00e+00	737.00
IUUC-Lpe-050821	Leersia perrieri	31.27	7.00e-96	344.00
IUUC-Loc-051849	Lepisosteus oculatus	71.27	0.00e+00	1182.00
IUUC-Lma-053297	Leptosphaeria maculans	34.73	2.00e-106	379.00
IUUC-Laf-053495	Loxodonta africana	80.48	0.00e+00	1337.00
IUUC-Meu-055983	Macropus eugenii	73.74	5.00e-168	584.00
IUUC-Mor-057006	Magnaporthe oryzae	37.89	3.00e-75	276.00
IUUC-Mpo-057465	Magnaporthe poae	37.20	1.00e-75	277.00
IUUC-Mtr-058374	Medicago truncatula	33.81	9.00e-111	394.00
IUUC-Mla-058895	Melampsora laricipopulina	36.65	4.00e-80	291.00
IUUC-Mvi-060297	Microbotryum violaceum	34.84	3.00e-110	392.00
IUUC-Mmr-060810	Microcebus murinus	75.09	0.00e+00	1224.00
IUUC-Mdo-062671	Monodelphis domestica	82.04	0.00e+00	1344.00
IUUC-Mmu-063536	Mus musculus	80.00	0.00e+00	1310.00
IUUC-Mac-064902	Musa acuminata	31.99	5.00e-99	355.00
IUUC-Mpu-066085	Mustela putorius furo	80.90	0.00e+00	1347.00
IUUC-Mlu-067907	Myotis lucifugus	80.65	0.00e+00	882.00
IUUC-Nfi-068457	Neosartorya fischeri	32.61	7.00e-74	271.00
IUUC-Ncr-068622	Neurospora crassa	31.85	1.00e-97	350.00
IUUC-Nle-069049	Nomascus leucogenys	79.37	0.00e+00	1308.00
IUUC-Opr-071013	Ochotona princeps	62.72	7.00e-156	544.00
IUUC-Ont-071339	Oreochromis niloticus	69.01	0.00e+00	1140.00
IUUC-Oan-073353	Ornithorhynchus anatinus	86.90	3.00e-115	407.00
IUUC-Ocu-074625	Oryctolagus cuniculus	80.25	0.00e+00	1339.00
IUUC-Oba-075226	Oryza barthii	28.73	2.00e-80	293.00
IUUC-Obr-076875	Oryza brachyantha	32.91	3.00e-106	379.00
IUUC-Ogl-077057	Oryza glaberrima	32.28	1.00e-105	377.00
IUUC-Ogu-078156	Oryza glumaepatula	31.91	2.00e-105	376.00
IUUC-Oin-079373	Oryza indica	31.78	4.00e-104	372.00
IUUC-Olo-080849	Oryza longistaminata	29.07	2.00e-69	256.00
IUUC-Ome-081654	Oryza meridionalis	28.14	1.00e-80	294.00
IUUC-Oni-082221	Oryza nivara	28.14	1.00e-82	300.00
IUUC-Opu-084103	Oryza punctata	28.52	3.00e-81	296.00
IUUC-Oru-084751	Oryza rufipogon	27.78	3.00e-79	289.00
IUUC-Osa-085584	Oryza sativa	31.91	3.00e-105	376.00
IUUC-Ola-086974	Oryzias latipes	66.92	0.00e+00	1124.00
IUUC-Oga-088052	Otolemur garnettii	75.75	0.00e+00	1249.00
IUUC-Oar-089509	Ovis aries	79.95	0.00e+00	1322.00
IUUC-Ptr-090911	Pan troglodytes	80.13	0.00e+00	1336.00
IUUC-Pan-092141	Papio anubis	80.08	0.00e+00	1330.00
IUUC-Psi-093543	Pelodiscus sinensis	83.22	0.00e+00	1289.00
IUUC-Pno-094952	Phaeosphaeria nodorum	34.20	1.00e-101	364.00
IUUC-Ppa-095881	Physcomitrella patens	33.08	3.00e-112	399.00
IUUC-Pfo-096739	Poecilia formosa	67.25	0.00e+00	1117.00
IUUC-Pab-098641	Pongo abelii	80.25	0.00e+00	1337.00
IUUC-Pop-099621	Populus trichocarpa	30.83	7.00e-101	361.00
IUUC-Pca-100599	Procavia capensis	72.92	0.00e+00	1118.00
IUUC-Ppe-101874	Prunus persica	32.12	5.00e-104	372.00
IUUC-Pva-103009	Pteropus vampyrus	78.41	0.00e+00	1093.00
IUUC-Pgr-103260	Puccinia graminis	33.89	9.00e-96	344.00
IUUC-Ptt-103711	Puccinia triticina	32.82	7.00e-92	331.00
IUUC-Pte-104337	Pyrenophora teres	33.98	9.00e-96	344.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	34.24	3.00e-97	349.00
IUUC-Rno-105273	Rattus norvegicus	79.87	0.00e+00	1337.00
IUUC-Sce-106351	Saccharomyces cerevisiae	41.44	9.00e-85	307.00
IUUC-Sha-106758	Sarcophilus harrisii	81.60	0.00e+00	1348.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	32.01	2.00e-92	333.00
IUUC-Spo-108093	Schizosaccharomyces pombe	33.24	8.00e-99	354.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	33.90	6.00e-97	348.00
IUUC-Smo-109368	Selaginella moellendorffii	33.00	2.00e-98	353.00
IUUC-Sit-109699	Setaria italica	33.20	3.00e-106	379.00
IUUC-Sly-111063	Solanum lycopersicum	32.42	5.00e-100	358.00
IUUC-Sar-113199	Sorex araneus	85.46	0.00e+00	736.00
IUUC-Sbi-114745	Sorghum bicolor	32.97	1.00e-98	353.00
IUUC-Sre-115080	Sporisorium reilianum	39.69	5.00e-98	352.00
IUUC-Ssc-115666	Sus scrofa	80.12	0.00e+00	1329.00
IUUC-Tgu-116877	Taeniopygia guttata	82.54	0.00e+00	1376.00
IUUC-Tru-117580	Takifugu rubripes	67.21	0.00e+00	1133.00
IUUC-Tsy-118946	Tarsius syrichta	80.27	0.00e+00	1236.00
IUUC-Tni-119755	Tetraodon nigroviridis	63.97	0.00e+00	1054.00
IUUC-Tca-120977	Theobroma cacao	31.48	4.00e-100	358.00
IUUC-Tre-122217	Trichoderma reesei	33.33	3.00e-100	359.00
IUUC-Tvi-122671	Trichoderma virens	32.42	2.00e-98	353.00
IUUC-Tae-125234	Triticum aestivum	31.96	3.00e-101	362.00
IUUC-Tur-126404	Triticum urartu	25.76	6.00e-21	95.90
IUUC-Tme-126971	Tuber melanosporum	35.40	2.00e-111	396.00
IUUC-Tbe-127858	Tupaia belangeri	61.57	2.00e-146	513.00
IUUC-Ttr-128173	Tursiops truncatus	79.27	0.00e+00	1298.00
IUUC-Uma-129322	Ustilago maydis	33.25	3.00e-104	372.00
IUUC-Vda-129682	Verticillium dahliae	31.37	2.00e-85	310.00
IUUC-Vpa-130607	Vicugna pacos	79.36	0.00e+00	1215.00
IUUC-Vvi-131153	Vitis vinifera	33.16	2.00e-106	380.00
IUUC-Xtr-132208	Xenopus tropicalis	74.21	0.00e+00	1238.00
IUUC-Xma-133098	Xiphophorus maculatus	67.94	0.00e+00	1111.00
IUUC-Yli-134646	Yarrowia lipolytica	39.09	5.00e-96	345.00
IUUC-Zma-135920	Zea mays	30.95	5.00e-89	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence