iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132208

Ensembl Protein ID

ENSXETP00000020678.3

UniProt Accession

F7EC12; F7EC12_XENTR

Genbank Protein ID

ENSXETP00000020678

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01028726

Gene Name

plaa

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000009385.3	ENSXETT00000020678.3	ENSXETP00000020678.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-23	81.9	155	185
UBD/Beta-Prp	5.80e-59	199.9	36	304

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D++ik+W 
   Q: 155  GHTAAVWAVKIlPEqGLMLTGSADKSIKLWK 185
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
            ++ +++ srd++ ++w  ++++     l+++sgh+++v++v++ p ++     +++tg++D++i+v++l++ k+++tlkgh+++v+sl
   Q: 36   PGEGFVSVSRDRSARLWVPDSPNQefveLQRMSGHSNFVSSVCILPPSDlyprgLIATGGNDHNICVFSLDSAKPLYTLKGHKNTVCSL 124
           566689999********99999888899******************99999999*********************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfd 189
           s+ +   +l+sGs+d t +vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+ ++lW  k g++  t+ g h+d v+ l+  
   Q: 125  SSGK-FGTLLSGSWDTTGKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKSIKLW--KAGRCEMTFLG-HEDCVRGLATV 206
           ***9.9***************..9******.*********************************..88********9.********976 PP
   S: 190  sngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
            + +e++s+s+d +v+ w + tgec++++ ght+ ++ + ++pn++ +v++s+D+s riW  ++g++++t+ l+++sv++++v  +++ 
   Q: 207  ND-TEFLSCSNDASVRRWLI-TGECLQIYYGHTNYIYNICLFPNSQDFVTTSEDRSMRIW--KKGECTQTIRLPAQSVWCCCV--LDNG 289
           65.8**************99.***************************************..9********************..9999 PP
   S: 279  vlvlgsedskvniwk 293
            +v g++d++++++ 
   Q: 290  DIVVGASDGIIRVFT 304
           *************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSQAGRDGGD NCYRLRCSLL GHELDVRGVA RCPLWPGEGF VSVSRDRSAR LWVPDSPNQE 60
FVELQRMSGH SNFVSSVCIL PPSDLYPRGL IATGGNDHNI CVFSLDSAKP LYTLKGHKNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCAGGCGTG TCCGTAATGA CGTAATCAAG AAGGGCTGTG GTTCCTCACA GCTTGTTGGC 60
TGGCAAGCAT GATGTATATA TACTGATGGT GCAGGTGCTT CTGTACATAG GTAGCCTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.73	2.00e-91	329.00
IUUC-Aml-002125	Ailuropoda melanoleuca	75.19	0.00e+00	1240.00
IUUC-Atr-002554	Amborella trichopoda	31.84	8.00e-102	364.00
IUUC-Apl-004094	Anas platyrhynchos	74.73	0.00e+00	1150.00
IUUC-Aca-004726	Anolis carolinensis	73.84	0.00e+00	1224.00
IUUC-Aly-005961	Arabidopsis lyrata	31.91	1.00e-102	367.00
IUUC-Ath-006639	Arabidopsis thaliana	32.33	1.00e-100	360.00
IUUC-Ago-007772	Ashbya gossypii	36.29	3.00e-73	269.00
IUUC-Acl-008316	Aspergillus clavatus	30.90	4.00e-79	289.00
IUUC-Afl-008532	Aspergillus flavus	33.46	7.00e-87	315.00
IUUC-Afu-008950	Aspergillus fumigatus	31.60	3.00e-81	296.00
IUUC-Ani-009186	Aspergillus nidulans	32.29	1.00e-86	313.00
IUUC-Ang-009575	Aspergillus niger	31.33	4.00e-81	295.00
IUUC-Aor-010086	Aspergillus oryzae	33.46	7.00e-87	315.00
IUUC-Ate-010541	Aspergillus terreus	30.99	4.00e-80	292.00
IUUC-Ame-011633	Astyanax mexicanus	64.86	0.00e+00	1056.00
IUUC-Bgr-012292	Blumeria graminis	30.20	7.00e-89	321.00
IUUC-Bta-013218	Bos taurus	75.22	0.00e+00	1243.00
IUUC-Bci-013876	Botrytis cinerea	31.82	1.00e-92	333.00
IUUC-Bdi-014810	Brachypodium distachyon	32.78	7.00e-104	371.00
IUUC-Bol-016006	Brassica oleracea	32.85	2.00e-103	370.00
IUUC-Bra-017593	Brassica rapa	32.20	2.00e-103	370.00
IUUC-Cel-018703	Caenorhabditis elegans	28.06	4.00e-72	266.00
IUUC-Cja-019270	Callithrix jacchus	74.94	0.00e+00	1241.00
IUUC-Cfa-021262	Canis familiaris	75.22	0.00e+00	1239.00
IUUC-Cpo-021449	Cavia porcellus	71.25	0.00e+00	1128.00
IUUC-Csa-024140	Chlorocebus sabaeus	75.19	0.00e+00	1247.00
IUUC-Cho-024923	Choloepus hoffmanni	68.59	1.00e-158	553.00
IUUC-Cin-025373	Ciona intestinalis	40.86	3.00e-168	585.00
IUUC-Csv-026324	Ciona savignyi	42.30	3.00e-179	621.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	30.63	2.00e-79	290.00
IUUC-Cne-026998	Cryptococcus neoformans	31.99	2.00e-88	320.00
IUUC-Cme-027154	Cyanidioschyzon merolae	31.26	1.00e-56	214.00
IUUC-Dre-028674	Danio rerio	65.41	0.00e+00	1071.00
IUUC-Dno-028966	Dasypus novemcinctus	74.81	0.00e+00	1243.00
IUUC-Dor-030343	Dipodomys ordii	67.00	0.00e+00	681.00
IUUC-Dse-031385	Dothistroma septosporum	29.99	1.00e-81	297.00
IUUC-Dme-032044	Drosophila melanogaster	35.95	1.00e-125	444.00
IUUC-Ete-032506	Echinops telfairi	66.67	0.00e+00	646.00
IUUC-Eca-033547	Equus caballus	75.50	0.00e+00	1254.00
IUUC-Eeu-034462	Erinaceus europaeus	63.13	2.00e-153	535.00
IUUC-Fca-035893	Felis catus	75.22	0.00e+00	1245.00
IUUC-Fal-037235	Ficedula albicollis	75.47	0.00e+00	1253.00
IUUC-Fox-037836	Fusarium oxysporum	31.69	1.00e-90	327.00
IUUC-Fso-038251	Fusarium solani	31.35	1.00e-88	320.00
IUUC-Gmo-038648	Gadus morhua	64.79	0.00e+00	913.00
IUUC-Ggr-039867	Gaeumannomyces graminis	35.89	1.00e-73	271.00
IUUC-Gga-040989	Gallus gallus	74.12	0.00e+00	1213.00
IUUC-Gac-041344	Gasterosteus aculeatus	65.21	0.00e+00	1038.00
IUUC-Gma-043067	Glycine max	31.18	4.00e-100	358.00
IUUC-Ggo-045009	Gorilla gorilla	74.84	0.00e+00	948.00
IUUC-Hsa-046807	Homo sapiens	74.81	0.00e+00	1240.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	75.19	0.00e+00	1253.00
IUUC-Kpa-049134	Komagataella pastoris	33.55	6.00e-83	301.00
IUUC-Lch-049597	Latimeria chalumnae	71.79	0.00e+00	705.00
IUUC-Lpe-050821	Leersia perrieri	31.86	1.00e-97	350.00
IUUC-Loc-051849	Lepisosteus oculatus	69.94	0.00e+00	1138.00
IUUC-Lma-053297	Leptosphaeria maculans	33.51	5.00e-102	365.00
IUUC-Laf-053495	Loxodonta africana	74.94	0.00e+00	1234.00
IUUC-Meu-055983	Macropus eugenii	65.99	1.00e-149	523.00
IUUC-Mor-057006	Magnaporthe oryzae	35.97	6.00e-73	268.00
IUUC-Mpo-057465	Magnaporthe poae	35.48	4.00e-73	269.00
IUUC-Mtr-058374	Medicago truncatula	32.41	3.00e-109	389.00
IUUC-Mla-058895	Melampsora laricipopulina	35.82	3.00e-75	275.00
IUUC-Mvi-060297	Microbotryum violaceum	33.93	4.00e-104	372.00
IUUC-Mmr-060810	Microcebus murinus	69.80	0.00e+00	1126.00
IUUC-Mdo-062671	Monodelphis domestica	74.81	0.00e+00	1229.00
IUUC-Mmu-063536	Mus musculus	74.06	0.00e+00	1214.00
IUUC-Mac-064902	Musa acuminata	32.61	8.00e-103	368.00
IUUC-Mpu-066085	Mustela putorius furo	75.35	0.00e+00	1251.00
IUUC-Mlu-067907	Myotis lucifugus	75.63	0.00e+00	813.00
IUUC-Nfi-068457	Neosartorya fischeri	31.03	4.00e-68	252.00
IUUC-Ncr-068622	Neurospora crassa	29.64	9.00e-92	331.00
IUUC-Nle-069049	Nomascus leucogenys	74.18	0.00e+00	1218.00
IUUC-Opr-071013	Ochotona princeps	58.13	1.00e-143	503.00
IUUC-Ont-071339	Oreochromis niloticus	66.92	0.00e+00	1093.00
IUUC-Oan-073353	Ornithorhynchus anatinus	80.79	1.00e-105	375.00
IUUC-Ocu-074625	Oryctolagus cuniculus	74.43	0.00e+00	1235.00
IUUC-Oba-075226	Oryza barthii	29.55	5.00e-84	305.00
IUUC-Obr-076875	Oryza brachyantha	32.58	7.00e-108	384.00
IUUC-Ogl-077057	Oryza glaberrima	32.58	6.00e-108	384.00
IUUC-Ogu-078156	Oryza glumaepatula	32.45	3.00e-107	382.00
IUUC-Oin-079373	Oryza indica	32.32	3.00e-106	379.00
IUUC-Olo-080849	Oryza longistaminata	28.98	4.00e-71	262.00
IUUC-Ome-081654	Oryza meridionalis	28.91	1.00e-83	304.00
IUUC-Oni-082221	Oryza nivara	29.17	8.00e-86	311.00
IUUC-Opu-084103	Oryza punctata	28.97	5.00e-85	308.00
IUUC-Oru-084751	Oryza rufipogon	28.79	3.00e-82	299.00
IUUC-Osa-085584	Oryza sativa	32.32	6.00e-106	378.00
IUUC-Ola-086974	Oryzias latipes	66.50	0.00e+00	1096.00
IUUC-Oga-088052	Otolemur garnettii	71.57	0.00e+00	1166.00
IUUC-Oar-089509	Ovis aries	74.56	0.00e+00	1229.00
IUUC-Ptr-090911	Pan troglodytes	74.81	0.00e+00	1239.00
IUUC-Pan-092141	Papio anubis	75.03	0.00e+00	1239.00
IUUC-Psi-093543	Pelodiscus sinensis	75.00	0.00e+00	1164.00
IUUC-Pno-094952	Phaeosphaeria nodorum	33.20	6.00e-97	348.00
IUUC-Ppa-095881	Physcomitrella patens	33.64	6.00e-112	398.00
IUUC-Pfo-096739	Poecilia formosa	65.66	0.00e+00	1078.00
IUUC-Pab-098641	Pongo abelii	74.94	0.00e+00	1239.00
IUUC-Pop-099621	Populus trichocarpa	31.87	1.00e-106	380.00
IUUC-Pca-100599	Procavia capensis	67.74	0.00e+00	1035.00
IUUC-Ppe-101874	Prunus persica	31.10	2.00e-105	376.00
IUUC-Pva-103009	Pteropus vampyrus	71.70	0.00e+00	1011.00
IUUC-Pgr-103260	Puccinia graminis	32.15	3.00e-95	342.00
IUUC-Ptt-103711	Puccinia triticina	31.74	4.00e-87	315.00
IUUC-Pte-104337	Pyrenophora teres	32.60	1.00e-90	327.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	32.86	1.00e-91	330.00
IUUC-Rno-105273	Rattus norvegicus	74.43	0.00e+00	1236.00
IUUC-Sce-106351	Saccharomyces cerevisiae	40.24	2.00e-79	290.00
IUUC-Sha-106758	Sarcophilus harrisii	74.15	0.00e+00	1226.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.12	8.00e-93	334.00
IUUC-Spo-108093	Schizosaccharomyces pombe	41.28	9.00e-95	341.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	37.60	3.00e-88	319.00
IUUC-Smo-109368	Selaginella moellendorffii	31.90	2.00e-92	333.00
IUUC-Sit-109699	Setaria italica	32.95	4.00e-110	392.00
IUUC-Sly-111063	Solanum lycopersicum	32.63	3.00e-100	359.00
IUUC-Sar-113199	Sorex araneus	80.60	0.00e+00	691.00
IUUC-Sbi-114745	Sorghum bicolor	32.61	1.00e-101	364.00
IUUC-Sre-115080	Sporisorium reilianum	39.25	1.00e-96	347.00
IUUC-Ssc-115666	Sus scrofa	74.34	0.00e+00	1232.00
IUUC-Tgu-116877	Taeniopygia guttata	74.72	0.00e+00	1237.00
IUUC-Tru-117580	Takifugu rubripes	65.54	0.00e+00	1087.00
IUUC-Tsy-118946	Tarsius syrichta	75.07	0.00e+00	1159.00
IUUC-Tni-119755	Tetraodon nigroviridis	63.54	0.00e+00	1029.00
IUUC-Tca-120977	Theobroma cacao	30.16	3.00e-101	362.00
IUUC-Tre-122217	Trichoderma reesei	31.21	6.00e-94	338.00
IUUC-Tvi-122671	Trichoderma virens	29.94	1.00e-89	324.00
IUUC-Tae-125581	Triticum aestivum	32.56	5.00e-105	375.00
IUUC-Tur-126404	Triticum urartu	24.46	3.00e-25	110.00
IUUC-Tme-126971	Tuber melanosporum	33.67	2.00e-107	383.00
IUUC-Tbe-127858	Tupaia belangeri	57.40	5.00e-134	471.00
IUUC-Ttr-128173	Tursiops truncatus	73.24	0.00e+00	1201.00
IUUC-Uma-129322	Ustilago maydis	33.25	7.00e-105	375.00
IUUC-Vda-129682	Verticillium dahliae	30.75	1.00e-80	294.00
IUUC-Vpa-130607	Vicugna pacos	73.23	0.00e+00	1132.00
IUUC-Vvi-131153	Vitis vinifera	32.59	1.00e-107	384.00
IUUC-Xma-133098	Xiphophorus maculatus	66.16	0.00e+00	1075.00
IUUC-Yli-134646	Yarrowia lipolytica	38.72	3.00e-92	332.00
IUUC-Zma-135920	Zea mays	31.86	5.00e-95	342.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence