iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005001

UUCD1 version

UUC-AnC-00909

Ensembl Protein ID

ENSACAP00000002438.2

UniProt Accession

G1KAU9; G1KAU9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002551.3	ENSACAT00000002501.3	ENSACAP00000002438.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	9.90e-55	184.1	8	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  
   Q: 8    RLMRDFKRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLIIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ-- 93
           9**********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 94   NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 142
           **********************************************996 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GTFKLIIEFS 60
EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAATGCC CAGGGTGGGA GAAAGAACTC TTGTCTGTTG GCGGCAAGTG TGAATGTTGC 60
AATTAATCAT CTTGATTGGC ACGGAAAAGC CTGGCAGCTT CAAAGCCTGG CTGTTACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

KEGG

acs:100551860

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	74.50	3.00e-68	249.00
IUUC-Aml-002120	Ailuropoda melanoleuca	99.34	7.00e-88	315.00
IUUC-Atr-002862	Amborella trichopoda	76.67	2.00e-70	257.00
IUUC-Apl-004063	Anas platyrhynchos	91.95	2.00e-76	276.00
IUUC-Aly-005584	Arabidopsis lyrata	76.51	1.00e-69	254.00
IUUC-Ath-007149	Arabidopsis thaliana	76.51	1.00e-69	254.00
IUUC-Ago-007745	Ashbya gossypii	69.80	8.00e-63	232.00
IUUC-Acl-008139	Aspergillus clavatus	68.21	1.00e-63	234.00
IUUC-Afl-008551	Aspergillus flavus	68.21	2.00e-63	234.00
IUUC-Afu-008980	Aspergillus fumigatus	68.21	2.00e-63	234.00
IUUC-Ang-009554	Aspergillus niger	68.21	2.00e-63	234.00
IUUC-Aor-010242	Aspergillus oryzae	68.21	2.00e-63	234.00
IUUC-Ate-010390	Aspergillus terreus	68.21	2.00e-63	234.00
IUUC-Ame-010743	Astyanax mexicanus	96.05	1.00e-84	304.00
IUUC-Bta-012840	Bos taurus	99.34	7.00e-88	315.00
IUUC-Bci-013919	Botrytis cinerea	68.42	2.00e-64	237.00
IUUC-Bdi-015010	Brachypodium distachyon	75.84	4.00e-69	253.00
IUUC-Bol-015726	Brassica oleracea	76.51	3.00e-69	256.00
IUUC-Bra-018026	Brassica rapa	76.51	8.00e-70	255.00
IUUC-Cel-018244	Caenorhabditis elegans	84.56	2.00e-76	277.00
IUUC-Cja-019737	Callithrix jacchus	99.34	7.00e-88	315.00
IUUC-Cfa-020244	Canis familiaris	99.34	7.00e-88	315.00
IUUC-Cpo-022192	Cavia porcellus	99.34	7.00e-88	315.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	75.97	1.00e-57	215.00
IUUC-Csa-023430	Chlorocebus sabaeus	99.34	7.00e-88	315.00
IUUC-Cho-024773	Choloepus hoffmanni	79.61	1.00e-64	238.00
IUUC-Cin-025537	Ciona intestinalis	80.92	2.00e-61	227.00
IUUC-Csv-025846	Ciona savignyi	82.00	1.00e-66	244.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	68.21	3.00e-64	236.00
IUUC-Cne-026864	Cryptococcus neoformans	69.80	6.00e-64	236.00
IUUC-Cme-027284	Cyanidioschyzon merolae	66.67	4.00e-54	204.00
IUUC-Dre-028774	Danio rerio	95.39	9.00e-85	305.00
IUUC-Dno-029661	Dasypus novemcinctus	99.34	7.00e-88	315.00
IUUC-Dor-030452	Dipodomys ordii	99.27	3.00e-78	283.00
IUUC-Dse-031487	Dothistroma septosporum	68.21	8.00e-64	235.00
IUUC-Dme-031863	Drosophila melanogaster	86.09	2.00e-76	277.00
IUUC-Ete-032595	Echinops telfairi	96.05	4.00e-85	306.00
IUUC-Eca-033377	Equus caballus	99.34	7.00e-88	315.00
IUUC-Eeu-035191	Erinaceus europaeus	76.62	2.00e-61	227.00
IUUC-Fca-036336	Felis catus	99.34	7.00e-88	315.00
IUUC-Fox-037808	Fusarium oxysporum	68.21	5.00e-64	235.00
IUUC-Fso-038232	Fusarium solani	68.21	6.00e-64	235.00
IUUC-Gmo-038517	Gadus morhua	95.39	2.00e-84	303.00
IUUC-Ggr-039875	Gaeumannomyces graminis	68.46	2.00e-63	233.00
IUUC-Gga-040494	Gallus gallus	99.34	7.00e-88	315.00
IUUC-Gac-042471	Gasterosteus aculeatus	96.05	2.00e-85	307.00
IUUC-Gma-043865	Glycine max	77.18	2.00e-70	257.00
IUUC-Ggo-044896	Gorilla gorilla	95.39	2.00e-84	303.00
IUUC-Hsa-046239	Homo sapiens	99.34	7.00e-88	315.00
IUUC-Hvu-047054	Hordeum vulgare	74.50	3.00e-68	249.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	99.34	7.00e-88	315.00
IUUC-Kpa-049225	Komagataella pastoris	68.67	2.00e-62	230.00
IUUC-Lch-050283	Latimeria chalumnae	96.69	1.00e-85	307.00
IUUC-Lpe-051301	Leersia perrieri	76.51	9.00e-70	254.00
IUUC-Loc-051962	Lepisosteus oculatus	97.37	3.00e-86	309.00
IUUC-Lma-053214	Leptosphaeria maculans	43.07	4.00e-32	130.00
IUUC-Laf-053380	Loxodonta africana	99.34	7.00e-88	315.00
IUUC-Mcc-054819	Macaca mulatta	99.34	4.00e-88	316.00
IUUC-Meu-056231	Macropus eugenii	95.39	2.00e-84	303.00
IUUC-Mpo-057498	Magnaporthe poae	68.46	3.00e-63	234.00
IUUC-Mtr-058305	Medicago truncatula	76.51	6.00e-70	255.00
IUUC-Mla-058876	Melampsora laricipopulina	73.51	1.00e-58	218.00
IUUC-Mga-059863	Meleagris gallopavo	97.86	5.00e-79	285.00
IUUC-Mvi-060330	Microbotryum violaceum	72.85	5.00e-58	216.00
IUUC-Mmr-060630	Microcebus murinus	99.34	7.00e-88	315.00
IUUC-Mdo-062676	Monodelphis domestica	99.34	7.00e-88	315.00
IUUC-Mmu-063491	Mus musculus	99.34	7.00e-88	315.00
IUUC-Mac-064774	Musa acuminata	76.51	1.00e-69	254.00
IUUC-Mpu-065803	Mustela putorius furo	99.34	7.00e-88	315.00
IUUC-Mlu-067147	Myotis lucifugus	99.34	7.00e-88	315.00
IUUC-Nfi-068580	Neosartorya fischeri	68.21	2.00e-63	234.00
IUUC-Ncr-068913	Neurospora crassa	68.21	3.00e-64	236.00
IUUC-Nle-070105	Nomascus leucogenys	99.34	7.00e-88	315.00
IUUC-Opr-070935	Ochotona princeps	99.34	7.00e-88	315.00
IUUC-Ont-071335	Oreochromis niloticus	96.05	2.00e-85	306.00
IUUC-Oan-072706	Ornithorhynchus anatinus	93.96	2.00e-80	290.00
IUUC-Ocu-074130	Oryctolagus cuniculus	99.34	7.00e-88	315.00
IUUC-Oba-075896	Oryza barthii	75.84	3.00e-69	253.00
IUUC-Obr-076713	Oryza brachyantha	76.51	9.00e-70	254.00
IUUC-Ogl-077116	Oryza glaberrima	76.51	9.00e-70	254.00
IUUC-Ogu-078696	Oryza glumaepatula	76.51	9.00e-70	254.00
IUUC-Oin-079099	Oryza indica	76.51	9.00e-70	254.00
IUUC-Olo-081018	Oryza longistaminata	64.85	3.00e-60	224.00
IUUC-Ome-081285	Oryza meridionalis	76.51	9.00e-70	254.00
IUUC-Oni-082088	Oryza nivara	76.51	9.00e-70	254.00
IUUC-Opu-083310	Oryza punctata	76.51	9.00e-70	254.00
IUUC-Oru-084449	Oryza rufipogon	76.51	9.00e-70	254.00
IUUC-Osa-085923	Oryza sativa	76.51	9.00e-70	254.00
IUUC-Ola-087160	Oryzias latipes	96.05	2.00e-85	306.00
IUUC-Olu-087830	Ostreococcus lucimarinus	78.52	2.00e-61	227.00
IUUC-Oga-088836	Otolemur garnettii	99.34	7.00e-88	315.00
IUUC-Oar-090141	Ovis aries	99.34	7.00e-88	315.00
IUUC-Ptr-091453	Pan troglodytes	99.34	7.00e-88	315.00
IUUC-Pan-092511	Papio anubis	99.34	7.00e-88	315.00
IUUC-Psi-093968	Pelodiscus sinensis	100.00	5.00e-88	315.00
IUUC-Pma-094376	Petromyzon marinus	92.76	5.00e-83	298.00
IUUC-Pno-094935	Phaeosphaeria nodorum	68.21	3.00e-64	236.00
IUUC-Ppa-095689	Physcomitrella patens	76.51	1.00e-60	224.00
IUUC-Pfo-096656	Poecilia formosa	94.74	3.00e-84	303.00
IUUC-Pab-098121	Pongo abelii	99.34	7.00e-88	315.00
IUUC-Pop-099517	Populus trichocarpa	76.51	8.00e-70	255.00
IUUC-Pca-100906	Procavia capensis	88.82	2.00e-76	277.00
IUUC-Ppe-101594	Prunus persica	76.51	1.00e-69	254.00
IUUC-Pva-102380	Pteropus vampyrus	94.08	2.00e-81	293.00
IUUC-Pgr-103611	Puccinia graminis	72.85	7.00e-59	219.00
IUUC-Ptt-103971	Puccinia triticina	73.73	1.00e-44	171.00
IUUC-Pte-104378	Pyrenophora teres	68.87	1.00e-64	237.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	68.87	1.00e-64	237.00
IUUC-Rno-105772	Rattus norvegicus	99.34	3.00e-88	317.00
IUUC-Sce-106283	Saccharomyces cerevisiae	69.80	7.00e-63	232.00
IUUC-Sha-107650	Sarcophilus harrisii	98.03	5.00e-86	308.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	71.14	3.00e-58	216.00
IUUC-Spo-108073	Schizosaccharomyces pombe	71.14	2.00e-58	217.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	68.42	2.00e-64	237.00
IUUC-Smo-109512	Selaginella moellendorffii	76.51	4.00e-70	256.00
IUUC-Sit-110731	Setaria italica	76.51	9.00e-70	254.00
IUUC-Sly-111506	Solanum lycopersicum	77.18	4.00e-70	256.00
IUUC-Stu-112080	Solanum tuberosum	77.18	4.00e-70	256.00
IUUC-Sar-113429	Sorex araneus	99.34	7.00e-88	315.00
IUUC-Sbi-114289	Sorghum bicolor	76.51	9.00e-70	254.00
IUUC-Sre-115106	Sporisorium reilianum	73.51	1.00e-59	221.00
IUUC-Ssc-115257	Sus scrofa	97.37	8.00e-86	308.00
IUUC-Tgu-116604	Taeniopygia guttata	93.21	1.00e-85	307.00
IUUC-Tru-118576	Takifugu rubripes	94.74	8.00e-84	301.00
IUUC-Tsy-119000	Tarsius syrichta	99.34	7.00e-88	315.00
IUUC-Tni-119745	Tetraodon nigroviridis	94.74	5.00e-84	302.00
IUUC-Tca-121827	Theobroma cacao	76.51	6.00e-70	255.00
IUUC-Tre-122002	Trichoderma reesei	68.21	9.00e-64	235.00
IUUC-Tvi-122331	Trichoderma virens	68.21	9.00e-64	235.00
IUUC-Tae-124461	Triticum aestivum	75.17	3.00e-69	254.00
IUUC-Tur-126866	Triticum urartu	75.17	5.00e-69	252.00
IUUC-Tme-127148	Tuber melanosporum	70.47	3.00e-64	236.00
IUUC-Tbe-127921	Tupaia belangeri	97.37	2.00e-83	300.00
IUUC-Ttr-129121	Tursiops truncatus	99.34	7.00e-88	315.00
IUUC-Uma-129561	Ustilago maydis	73.51	5.00e-60	223.00
IUUC-Vda-129711	Verticillium dahliae	68.21	3.00e-64	236.00
IUUC-Vpa-130570	Vicugna pacos	92.70	3.00e-71	259.00
IUUC-Vvi-131108	Vitis vinifera	77.85	2.00e-70	257.00
IUUC-Xtr-131824	Xenopus tropicalis	98.03	1.00e-86	311.00
IUUC-Xma-133667	Xiphophorus maculatus	96.05	2.00e-85	306.00
IUUC-Yli-134660	Yarrowia lipolytica	65.56	7.00e-63	232.00
IUUC-Zma-135584	Zea mays	75.17	8.00e-69	252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence