iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Smo-109640

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-protein ligase, UPL1

Genbank Nucleotide ID

GL377611

Gene Name

UPL1-2; SELMODRAFT_154179

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_154179	EFJ18137	EFJ18137

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-120	402.5	3206	3544
UBD/Alpha-Helix/UBA	3.00e-07	31.1	1256	1295

Active Site

Position(s)	Description	Evidence
3512	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +++k rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Gr++ kal+dg+lld+ +++sfyk++l
   Q: 3206 DEVKGRLTVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQ-TEHLSYFKFVGRVVSKALFDGQLLDVYFTRSFYKHIL 3302
           67899*********************************99995.55577788******986.5************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveaf 193
           g+k++++d+e+vdp++yk+lk+++en   d++++ l ltfs++ ++         e++++eL+pgG+ni+Vt+eNk+eYv+l++e+rl++ i+ q++af
   Q: 3303 GTKVTYHDIEAVDPDYYKNLKWLLEN---DVNDI-LGLTFSIDADEekhilyeKTEVTDHELVPGGRNIRVTEENKHEYVDLIAEHRLTTAIRPQINAF 3397
           ************************99...77776.77777766555568895555566778************************************** PP
   S: 194  reGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
            eGfne++p el+s+F+ +elelli+G +eid++dl+++t+y+g y++ sp++qwFwev+++fs+e+ +++LqF+Tg+s++Pl+Gf++l+    p++f+
   Q: 3398 LEGFNELVPRELISIFNDKELELLISGLPEIDLDDLRANTEYTG-YSSGSPVVQWFWEVVQDFSKEDMARLLQFITGTSKVPLEGFKALQgisgPQKFQ 3495
           ******************************************66.****************************************************** PP
   S: 289  irk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           i+k +++++rlPs++TCfn+L+LPeYssk++++++Ll+Ai+e+ +gF++
   Q: 3496 IHKaYGAPERLPSAHTCFNQLDLPEYSSKDQMHDRLLLAIHEAsEGFGF 3544
           ***99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de ++  ++eMGF+r +a  aLr++   ++e A+e+L+++
   Q: 1256 DEALISTIMEMGFPRARAEAALRNSeASSVELAMEWLFTH 1295
           7889**********************************98 PP

Organism

Selaginella moellendorffii

Protein Sequence
(Fasta)

MKVKRKRGAE TPPRIRSFIN NVVSTPLESI HTVLSSFYWD FEKGDFFHWL DLINHFDSFL 60
EKFVTSRKDL QLDLEGSDES DVPKEAVLQV LRVTRCLLDN CVNRSFYNSL EHLTVLLAST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTGA AGAGGAAGAG AGGCGCGGAG ACGGTAAGCT TTTGGATTCT CGCCCGCGCT 60
TCGGCGGCTT TGCATGCCTC TATAGTTCTT AGGGTTCTGT GTCCGGATTG AGCTGAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00185--ARM
SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

smo:SELMODRAFT_154179

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002582	Amborella trichopoda	38.92	0.00e+00	1169.00
IUUC-Apl-003400	Anas platyrhynchos	42.82	1.00e-97	350.00
IUUC-Aca-005263	Anolis carolinensis	52.80	2.00e-130	461.00
IUUC-Ago-008005	Ashbya gossypii	37.80	2.00e-123	437.00
IUUC-Acl-008254	Aspergillus clavatus	38.90	8.00e-136	479.00
IUUC-Afu-009022	Aspergillus fumigatus	38.74	2.00e-136	481.00
IUUC-Ani-009412	Aspergillus nidulans	43.65	3.00e-135	477.00
IUUC-Ate-010253	Aspergillus terreus	40.78	3.00e-137	484.00
IUUC-Bgr-012043	Blumeria graminis	38.64	2.00e-136	481.00
IUUC-Bol-015228	Brassica oleracea	37.82	2.00e-143	503.00
IUUC-Cpo-021766	Cavia porcellus	43.51	5.00e-100	358.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	62.41	5.00e-161	559.00
IUUC-Csv-025872	Ciona savignyi	50.58	2.00e-121	428.00
IUUC-Cne-027095	Cryptococcus neoformans	30.67	1.00e-107	385.00
IUUC-Cme-027267	Cyanidioschyzon merolae	52.96	1.00e-127	451.00
IUUC-Ete-032966	Echinops telfairi	43.28	6.00e-100	358.00
IUUC-Fal-036687	Ficedula albicollis	43.05	1.00e-98	353.00
IUUC-Fso-038464	Fusarium solani	40.69	7.00e-140	493.00
IUUC-Gga-040845	Gallus gallus	42.82	3.00e-98	352.00
IUUC-Ggo-044465	Gorilla gorilla	43.18	5.00e-98	351.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	53.04	2.00e-130	460.00
IUUC-Kpa-049228	Komagataella pastoris	39.78	7.00e-130	459.00
IUUC-Lch-050252	Latimeria chalumnae	52.87	2.00e-129	458.00
IUUC-Lpe-050915	Leersia perrieri	45.73	0.00e+00	2489.00
IUUC-Mcc-055085	Macaca mulatta	53.16	2.00e-130	461.00
IUUC-Meu-056751	Macropus eugenii	43.94	5.00e-76	279.00
IUUC-Mpo-057597	Magnaporthe poae	40.12	9.00e-138	486.00
IUUC-Mla-058888	Melampsora laricipopulina	48.78	2.00e-119	421.00
IUUC-Mga-059935	Meleagris gallopavo	42.82	2.00e-98	352.00
IUUC-Mpu-066653	Mustela putorius furo	53.16	3.00e-130	461.00
IUUC-Nfi-068278	Neosartorya fischeri	38.73	1.00e-136	482.00
IUUC-Ncr-068813	Neurospora crassa	40.59	8.00e-148	519.00
IUUC-Oba-075757	Oryza barthii	48.85	0.00e+00	1157.00
IUUC-Obr-076762	Oryza brachyantha	43.14	0.00e+00	1327.00
IUUC-Ogl-077520	Oryza glaberrima	48.92	0.00e+00	1154.00
IUUC-Ogu-077981	Oryza glumaepatula	43.59	0.00e+00	1335.00
IUUC-Oin-079767	Oryza indica	48.92	0.00e+00	1157.00
IUUC-Olo-080380	Oryza longistaminata	47.80	0.00e+00	1119.00
IUUC-Ome-081925	Oryza meridionalis	48.72	0.00e+00	1151.00
IUUC-Oni-082619	Oryza nivara	48.78	0.00e+00	1156.00
IUUC-Opu-083428	Oryza punctata	43.16	0.00e+00	1294.00
IUUC-Oru-084501	Oryza rufipogon	48.92	0.00e+00	1157.00
IUUC-Ola-086777	Oryzias latipes	43.74	5.00e-99	355.00
IUUC-Olu-087813	Ostreococcus lucimarinus	53.77	2.00e-129	454.00
IUUC-Ptr-090529	Pan troglodytes	43.28	1.00e-99	357.00
IUUC-Psi-093969	Pelodiscus sinensis	42.60	2.00e-98	352.00
IUUC-Pma-094364	Petromyzon marinus	43.26	6.00e-88	317.00
IUUC-Pfo-096232	Poecilia formosa	52.80	1.00e-129	459.00
IUUC-Pca-100596	Procavia capensis	42.53	3.00e-87	315.00
IUUC-Ppe-102109	Prunus persica	47.19	0.00e+00	2724.00
IUUC-Pgr-103465	Puccinia graminis	45.01	1.00e-129	459.00
IUUC-Ptt-103813	Puccinia triticina	42.86	3.00e-120	427.00
IUUC-Rno-105153	Rattus norvegicus	43.28	5.00e-100	358.00
IUUC-Sce-106449	Saccharomyces cerevisiae	30.03	7.00e-126	446.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	40.28	2.00e-135	478.00
IUUC-Spo-108024	Schizosaccharomyces pombe	40.53	4.00e-137	483.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	43.56	2.00e-93	336.00
IUUC-Sit-110149	Setaria italica	43.40	0.00e+00	1278.00
IUUC-Sly-111285	Solanum lycopersicum	43.01	0.00e+00	1613.00
IUUC-Stu-112501	Solanum tuberosum	57.80	1.00e-103	368.00
IUUC-Sbi-114042	Sorghum bicolor	50.10	0.00e+00	1166.00
IUUC-Sre-114958	Sporisorium reilianum	55.74	9.00e-143	499.00
IUUC-Tgu-117225	Taeniopygia guttata	42.82	2.00e-98	352.00
IUUC-Tsy-119407	Tarsius syrichta	49.41	2.00e-94	339.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.87	1.00e-125	445.00
IUUC-Tre-121909	Trichoderma reesei	41.85	1.00e-147	518.00
IUUC-Tvi-122370	Trichoderma virens	41.43	1.00e-147	518.00
IUUC-Tme-127172	Tuber melanosporum	39.28	1.00e-134	475.00
IUUC-Tbe-127408	Tupaia belangeri	42.44	3.00e-84	306.00
IUUC-Uma-129355	Ustilago maydis	51.43	1.00e-144	505.00
IUUC-Vvi-131559	Vitis vinifera	48.25	0.00e+00	1110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence