iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.90e-09	37.0	111	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl +f   d+++vlp CgH fh  C+  w         + +CP Cr
   Q: 111  CAICLAEFsaGDELRVLPqCGHGFHVACIDTW------LGSHSSCPSCR 153
           ********88555*******************......99********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Protein Sequence
(Fasta)

MARLLFRLLV ESNTPSPAID NSTAALNSDL VVILAALLCA LICVLGLIAV SRCVWLRRLA 60
AGNRTVSGSQ TQSPQPPVAA ANKGLKKKVL QSLPKLTFSP ESPESEKFAE CAICLAEFSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTAAAATGA CTAAAGTAAC CTTAACCGAC AACGATAGTT TTAAGACCAA ACCAGTAGAA 60
CTCTCCTCCT TCTATAAATC TCTGCTTCTC GTTGCCTCTC CAAAACCCTC TCAAACTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0070417--P:cellular response to cold
GO:0006952--P:defense response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0009909--P:regulation of flower development
GO:0010966--P:regulation of phosphate transport
GO:0010200--P:response to chitin

KEGG

ath:AT1G20823

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000545	Aegilops tauschii	55.42	3.00e-21	94.00
IUUC-Atr-002926	Amborella trichopoda	47.21	4.00e-24	103.00
IUUC-Aly-005933	Arabidopsis lyrata	94.92	2.00e-74	270.00
IUUC-Bdi-014058	Brachypodium distachyon	58.14	6.00e-25	106.00
IUUC-Bol-016283	Brassica oleracea	80.50	3.00e-66	243.00
IUUC-Bra-017385	Brassica rapa	80.69	1.00e-59	221.00
IUUC-Gma-042991	Glycine max	69.23	4.00e-37	146.00
IUUC-Hvu-047055	Hordeum vulgare	48.87	2.00e-29	120.00
IUUC-Lpe-050856	Leersia perrieri	48.95	1.00e-26	111.00
IUUC-Mac-064619	Musa acuminata	50.00	5.00e-30	123.00
IUUC-Oba-075502	Oryza barthii	48.50	7.00e-29	119.00
IUUC-Obr-076446	Oryza brachyantha	49.64	5.00e-31	125.00
IUUC-Ogl-077507	Oryza glaberrima	47.90	2.00e-28	117.00
IUUC-Ogu-078762	Oryza glumaepatula	48.50	7.00e-29	119.00
IUUC-Oin-079945	Oryza indica	53.23	5.00e-31	125.00
IUUC-Ome-081518	Oryza meridionalis	50.31	2.00e-28	117.00
IUUC-Oni-082929	Oryza nivara	51.28	2.00e-29	121.00
IUUC-Opu-083589	Oryza punctata	48.95	3.00e-27	115.00
IUUC-Oru-084673	Oryza rufipogon	47.90	2.00e-28	117.00
IUUC-Osa-085373	Oryza sativa	47.90	8.00e-29	119.00
IUUC-Ppe-101319	Prunus persica	63.83	2.00e-44	171.00
IUUC-Tca-121444	Theobroma cacao	61.42	3.00e-47	180.00
IUUC-Tae-124309	Triticum aestivum	54.22	4.00e-20	90.10
IUUC-Tur-126504	Triticum urartu	62.35	2.00e-26	111.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence