iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.00e-05	26.7	27	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklde 67
           +Dv+++vg+  f+ hk  L++ + + ++l +   ++s+ +  ++i d     e+f+   kF+Y   +d+
   Q: 27   SDVTVHVGEASFSLHKFPLMSKCGFIKKLVSESSKDSD-STVIKIPDipGGSEAFELAAKFCYGINFDM 94
           69***********************************9.********888899**********876665 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MSAKKKDLLS SAMKRTSEWI SSQEVSSDVT VHVGEASFSL HKFPLMSKCG FIKKLVSESS 60
KDSDSTVIKI PDIPGGSEAF ELAAKFCYGI NFDMSTENIA MLRCAAEYLE MTEEHSVENL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAATATCCC ATCATTCATG TTCTGTCACA AAACCAAGAT TCTGCAGCTT ACTTATATAC 60
TCCTTCCTTC TCTTCTTCTT ACCACTAAAC CAATTTATAG CTAATATTTG TAAGGGATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000210--BTB/POZ_dom
IPR027356--NPH3_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB
PS51649--NPH3

Pfam

PF03000--NPH3

SMART

SM00225--BTB

Gene Ontology

GO:0016567--P:protein ubiquitination

KEGG

ath:AT5G67385

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bol-015199	Brassica oleracea	88.82	0.00e+00	1009.00
IUUC-Lch-050276	Latimeria chalumnae	33.67	4.00e-06	46.20
IUUC-Oba-075965	Oryza barthii	33.33	1.00e-79	290.00
IUUC-Ogl-077703	Oryza glaberrima	34.03	6.00e-81	294.00
IUUC-Oin-079784	Oryza indica	34.03	7.00e-81	294.00
IUUC-Ome-081799	Oryza meridionalis	34.42	5.00e-80	291.00
IUUC-Oni-082767	Oryza nivara	33.90	7.00e-81	294.00
IUUC-Osa-085337	Oryza sativa	34.35	5.00e-74	271.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence