iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027586

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Transducin (beta)-like 1X-linked; Zgc:158242 protein

Genbank Nucleotide ID

CU469547

Gene Name

tbl1x; zgc:158242

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060438.4	ENSDART00000085135.4	ENSDARP00000079570.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-51	169.4	437	472
UBD/Beta-Prp	4.10e-61	207.7	303	508

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+++v+++af +d ++l+sGs D+ +++WD+ +g l
   Q: 437  HQEPVYSVAFsPDgKFLASGSFDKCVHIWDTMSGSL 472
           99*********999****************998876 PP

UBD/Beta-Prp

   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h++ +l+++++  +++++s s d  i+v  l ++  l+ t++gh+  vn ++++p+g ll+s+s+D t+++W++k+++++++l+  h +
   Q: 303  HSAPALDVDWQN-NSTFASCSTDMCIHVCRLGSERPLK-TFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDSCVHDLQA-HSK 388
           566666666665.6777777777777777777777777.7777777777777777777777777777777777777777777776.777 PP
   S: 182  svyslsfdsng.........kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
            +y ++++++g           l+s+s d+tv+lwd+ +g c +tl+ h+++v+sv+fsp++++l+sgs D+ + iWd+ sg l++++ 
   Q: 389  EIYTIKWSPTGigsnnpnanILLASASFDSTVRLWDVDRGVCTHTLTRHQEPVYSVAFSPDGKFLASGSFDKCVHIWDTMSGSLVNSYR 477
           77777777777777777776677777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 262  lhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           ++   +  v+  s+gd+v +++s d++v +++l
   Q: 478  GTG-GIFEVCWNSVGDKVGASAS-DGSVCVLDL 508
           644.4444444445555555553.345555554 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALV SVLQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVHSRQQAFR DKLSQHQHQG SSSSNSSVAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTCATAT AAACACAGGA AACTTGTGTA AAAATACATA TAATTCACAT TTAATCGTGA 60
TTTGACGCAC ACGGGAGCGC GCTTATTTCT ACACATCGAC GTTTTAACGG ACCGGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

dre:560294

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007869	Ashbya gossypii	25.74	3.00e-39	156.00
IUUC-Bdi-014315	Brachypodium distachyon	50.00	7.00e-150	524.00
IUUC-Kpa-049338	Komagataella pastoris	26.30	1.00e-38	154.00
IUUC-Oba-075618	Oryza barthii	47.03	6.00e-139	487.00
IUUC-Ogl-077302	Oryza glaberrima	49.19	4.00e-151	528.00
IUUC-Ogu-078718	Oryza glumaepatula	49.37	3.00e-151	528.00
IUUC-Oin-079515	Oryza indica	42.99	2.00e-91	330.00
IUUC-Ome-081696	Oryza meridionalis	48.29	1.00e-145	510.00
IUUC-Oni-082137	Oryza nivara	49.37	3.00e-151	528.00
IUUC-Opu-083505	Oryza punctata	47.21	1.00e-139	489.00
IUUC-Oru-085276	Oryza rufipogon	49.55	1.00e-151	530.00
IUUC-Osa-085791	Oryza sativa	49.37	3.00e-151	528.00
IUUC-Pma-094105	Petromyzon marinus	65.77	1.00e-100	359.00
IUUC-Tur-126856	Triticum urartu	41.18	5.00e-73	268.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence