iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069151

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01194155

Gene Name

TBL1X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000008726.2	ENSNLET00000011234.2	ENSNLEP00000010715.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.10e-54	177.0	502	540
UBD/Beta-Prp	9.80e-64	215.3	374	573

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 502  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGNLVHS 540
           9**********999********************99886 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++  c+h l++h+++++++++s
   Q: 374  DVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 461
           3333.444445555555555555555555555555555555555555555555555555555555555555555555555555555554 PP
   S: 104  p.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           p         s+  l+s+s d+t+r+wd+e g c + tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +
   Q: 462  PtgpatsnpnSNIMLASASFDSTVRLWDIERGVCTH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG--TGGI 547
           444433333222345555555555555555555555.5555555555555555555555555555555555555555555554..5555 PP
   S: 184  yslsfdsngkelvsgsldgtvklwdl 209
             + ++  g  + + + dg+v + dl
   Q: 548  FEVCWNARGDKVGASASDGSVCVLDL 573
           55555555555555555555554444 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MTELAGASSS CCHRPAGRGA MQSVLHHFQR LRGREGGSHF INTSSPRGEA KMSITSDEVN 60
FLVYRYLQES VFSHSAFTFG IESHISQSNI NGTLVPPAAL IFLLQKGLQY VEAEISINED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCATGTA ATACCTCAGC ATCAGTCTGC ACAAGCCCAG GGAGCCCAGG AGCAACGAAG 60
GGCAGGCTCA AGGGAAGGCC ACACCAAGTC CTTCTGGGGG GCCTTGAATG GCAACTGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0017053--C:transcriptional repressor complex
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006508--P:proteolysis
GO:0007605--P:sensory perception of sound

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	89.34	0.00e+00	995.00
IUUC-Apl-003232	Anas platyrhynchos	93.13	0.00e+00	971.00
IUUC-Aca-005035	Anolis carolinensis	92.66	0.00e+00	983.00
IUUC-Bta-013202	Bos taurus	93.18	0.00e+00	985.00
IUUC-Cja-019281	Callithrix jacchus	91.48	0.00e+00	1061.00
IUUC-Cfa-020929	Canis familiaris	92.21	0.00e+00	975.00
IUUC-Csa-023943	Chlorocebus sabaeus	97.22	0.00e+00	1115.00
IUUC-Dno-028926	Dasypus novemcinctus	91.65	0.00e+00	965.00
IUUC-Dme-031939	Drosophila melanogaster	80.38	3.00e-174	605.00
IUUC-Ete-032822	Echinops telfairi	82.86	0.00e+00	833.00
IUUC-Eca-033897	Equus caballus	93.16	0.00e+00	979.00
IUUC-Fca-036462	Felis catus	93.36	0.00e+00	977.00
IUUC-Fal-037388	Ficedula albicollis	93.70	0.00e+00	980.00
IUUC-Gga-040671	Gallus gallus	94.08	0.00e+00	980.00
IUUC-Gac-041851	Gasterosteus aculeatus	88.55	0.00e+00	922.00
IUUC-Ggo-045373	Gorilla gorilla	97.40	0.00e+00	1120.00
IUUC-Hsa-045841	Homo sapiens	97.57	0.00e+00	1127.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	95.97	0.00e+00	760.00
IUUC-Lch-050535	Latimeria chalumnae	90.08	0.00e+00	956.00
IUUC-Laf-054071	Loxodonta africana	93.01	0.00e+00	982.00
IUUC-Mcc-055233	Macaca mulatta	97.01	0.00e+00	1100.00
IUUC-Mtr-058624	Medicago truncatula	46.98	1.00e-136	480.00
IUUC-Mga-059895	Meleagris gallopavo	93.51	0.00e+00	984.00
IUUC-Mvi-060557	Microbotryum violaceum	37.30	2.00e-70	260.00
IUUC-Mmr-061286	Microcebus murinus	93.21	0.00e+00	989.00
IUUC-Mmu-063447	Mus musculus	93.17	0.00e+00	981.00
IUUC-Mac-065508	Musa acuminata	44.03	5.00e-100	357.00
IUUC-Ont-072252	Oreochromis niloticus	88.17	0.00e+00	939.00
IUUC-Oan-073562	Ornithorhynchus anatinus	92.98	0.00e+00	982.00
IUUC-Oba-075618	Oryza barthii	47.94	1.00e-142	499.00
IUUC-Ogl-077302	Oryza glaberrima	49.73	7.00e-154	536.00
IUUC-Ogu-078718	Oryza glumaepatula	49.73	7.00e-154	537.00
IUUC-Oin-079515	Oryza indica	43.92	7.00e-94	338.00
IUUC-Ome-081696	Oryza meridionalis	48.65	1.00e-148	519.00
IUUC-Oni-082137	Oryza nivara	49.73	7.00e-154	537.00
IUUC-Opu-083505	Oryza punctata	47.93	4.00e-142	498.00
IUUC-Oru-085276	Oryza rufipogon	49.73	3.00e-154	538.00
IUUC-Osa-085791	Oryza sativa	49.73	7.00e-154	537.00
IUUC-Oar-089506	Ovis aries	92.37	0.00e+00	980.00
IUUC-Ptr-090793	Pan troglodytes	90.46	0.00e+00	938.00
IUUC-Pan-091909	Papio anubis	97.23	0.00e+00	1120.00
IUUC-Psi-093358	Pelodiscus sinensis	88.95	0.00e+00	938.00
IUUC-Pma-094105	Petromyzon marinus	60.69	1.00e-99	356.00
IUUC-Pfo-097214	Poecilia formosa	86.64	0.00e+00	905.00
IUUC-Pab-098317	Pongo abelii	97.35	0.00e+00	1107.00
IUUC-Rno-105857	Rattus norvegicus	93.17	0.00e+00	981.00
IUUC-Sha-107326	Sarcophilus harrisii	91.41	0.00e+00	987.00
IUUC-Stu-112786	Solanum tuberosum	47.93	4.00e-141	494.00
IUUC-Ssc-115646	Sus scrofa	92.83	0.00e+00	1009.00
IUUC-Tgu-116898	Taeniopygia guttata	93.32	0.00e+00	973.00
IUUC-Tru-117862	Takifugu rubripes	88.40	0.00e+00	934.00
IUUC-Tni-119656	Tetraodon nigroviridis	88.49	0.00e+00	934.00
IUUC-Tae-125368	Triticum aestivum	49.46	3.00e-153	535.00
IUUC-Tur-126856	Triticum urartu	42.54	6.00e-75	274.00
IUUC-Ttr-128826	Tursiops truncatus	91.88	0.00e+00	921.00
IUUC-Uma-129469	Ustilago maydis	43.14	8.00e-59	222.00
IUUC-Vvi-131193	Vitis vinifera	59.26	2.00e-129	456.00
IUUC-Xma-133591	Xiphophorus maculatus	86.88	0.00e+00	913.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence