• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063566
Ensembl Protein ID ENSMUSP00000023918.6
UniProt Accession Q920Q8; Q06BK6; Q3TXI1; Q3UJE3; Q3UJS1; Q3UKH9; Q3UMK9; Q6ZQ34; Q99KN0; Q9D978; NS1BP_MOUSE
Genbank Protein ID BAB69058.1; BAB69059.1; ABI84241.1; BAC98039.1; BAB24936.1; BAE26089.1; BAE26221.1; BAE26822.1; BAE27084.1; BAE27212.1; BAE27326.1; BAE34935.1; AAH04092.1; AAH40250.1
Protein Name Influenza virus NS1A-binding protein homolog; Kelch family protein Nd1-L; ND1-L2; Nd1-S
Genbank Nucleotide ID AB055737; AB055738; DQ914522; AK129229; AK007291; AK144835; AK145071; AK146001; AK146329; AK146494; AK146645; AK159254; BC004092; BC040250
Gene Name Ivns1abp; Kiaa0850; Nd1; Nd1L; Nd1S; Ns1; Ns1bp
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000023150.14 ENSMUST00000023918.12 ENSMUSP00000023918.6
ENSMUSG00000023150.14 ENSMUST00000111887.9 ENSMUSP00000107518.3
ENSMUSG00000023150.14 ENSMUST00000097543.7 ENSMUSP00000095150.1
ENSMUSG00000023150.14 ENSMUST00000190872.1 ENSMUSP00000140332.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 4.10e-12 47.4 32 96
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv l+v g e  ah++vLa +S+++   f+++ +     + v+++d+ pe++++ll++ Yt +l+
   Q: 32   CDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHG-VSHVKLDDLNPEAVEVLLNYAYTAQLK 96
           8**********************************777.9************************97 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Plays a role in protecting the heart from doxorubicin-induced cardiomyopathy. Activates Erk signaling pathway when overexpressed in cultured cell lines.
 Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Plays a role in protecting the heart from doxorubicin-induced cardiomyopathy. Activates Erk signaling pathway when overexpressed in cultured cell lines.
Protein Sequence
(Fasta)
MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI 60
FNSDSDPHGV SHVKLDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063566|E3,BTB_Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTGGCGGCA GCGCACGTGG TGACGTGCGA GGGAGTGCGG CGCGAGCGCG CGCGGCGGCG 60
GCGGCGGTGG CAGTGTGTTC GGGACGCGCG TGGAGGTCGG TCAGTCGCTC GGAGGTGCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063566|E3,BTB_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0880--Kelch repeat
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029849--NS1BP
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:2001243--P:negative regulation of intrinsic apoptotic signaling pathway
KEGG mmu:117198
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001227 Ailuropoda melanoleuca 97.35 0.00e+00 1314.00
IUUC-Apl-003244 Anas platyrhynchos 90.06 0.00e+00 1217.00
IUUC-Aca-005134 Anolis carolinensis 89.88 0.00e+00 1204.00
IUUC-Ame-011309 Astyanax mexicanus 76.76 0.00e+00 1046.00
IUUC-Bta-013020 Bos taurus 97.20 0.00e+00 1291.00
IUUC-Cel-018672 Caenorhabditis elegans 28.08 1.00e-81 297.00
IUUC-Cja-018717 Callithrix jacchus 95.79 0.00e+00 1260.00
IUUC-Cfa-021209 Canis familiaris 97.20 0.00e+00 1290.00
IUUC-Cpo-022465 Cavia porcellus 96.42 0.00e+00 1306.00
IUUC-Csa-023264 Chlorocebus sabaeus 97.04 0.00e+00 1277.00
IUUC-Cho-024407 Choloepus hoffmanni 96.24 0.00e+00 1112.00
IUUC-Dre-027945 Danio rerio 77.26 0.00e+00 1060.00
IUUC-Dno-028942 Dasypus novemcinctus 91.90 0.00e+00 1229.00
IUUC-Ete-032283 Echinops telfairi 96.42 0.00e+00 1298.00
IUUC-Eca-033877 Equus caballus 96.80 0.00e+00 1015.00
IUUC-Eeu-034923 Erinaceus europaeus 88.63 0.00e+00 1161.00
IUUC-Fca-036378 Felis catus 97.20 0.00e+00 1313.00
IUUC-Fal-037161 Ficedula albicollis 87.28 0.00e+00 1000.00
IUUC-Gmo-039396 Gadus morhua 70.08 0.00e+00 880.00
IUUC-Gga-040338 Gallus gallus 93.64 2.00e-122 431.00
IUUC-Gac-042553 Gasterosteus aculeatus 74.96 0.00e+00 966.00
IUUC-Ggo-045612 Gorilla gorilla 96.88 0.00e+00 1276.00
IUUC-Hsa-045753 Homo sapiens 97.04 0.00e+00 1277.00
IUUC-Itr-048475 Ictidomys tridecemlineatus 97.98 0.00e+00 1322.00
IUUC-Lch-050220 Latimeria chalumnae 78.09 0.00e+00 1023.00
IUUC-Loc-051950 Lepisosteus oculatus 80.00 0.00e+00 1090.00
IUUC-Laf-053878 Loxodonta africana 96.57 0.00e+00 1285.00
IUUC-Mcc-055598 Macaca mulatta 97.04 0.00e+00 1278.00
IUUC-Meu-056133 Macropus eugenii 98.40 1.00e-144 506.00
IUUC-Mga-059538 Meleagris gallopavo 89.44 0.00e+00 1190.00
IUUC-Mmr-061279 Microcebus murinus 97.20 0.00e+00 1283.00
IUUC-Mdo-062952 Monodelphis domestica 95.17 0.00e+00 1293.00
IUUC-Mpu-065828 Mustela putorius furo 97.20 0.00e+00 1312.00
IUUC-Mlu-067313 Myotis lucifugus 96.12 0.00e+00 1259.00
IUUC-Nle-069890 Nomascus leucogenys 97.20 0.00e+00 1278.00
IUUC-Ont-072649 Oreochromis niloticus 76.49 0.00e+00 1001.00
IUUC-Oan-073447 Ornithorhynchus anatinus 93.63 0.00e+00 1240.00
IUUC-Ocu-074680 Oryctolagus cuniculus 90.60 0.00e+00 1176.00
IUUC-Ogu-078293 Oryza glumaepatula 29.73 7.00e-13 68.20
IUUC-Ome-081176 Oryza meridionalis 29.09 2.00e-07 50.10
IUUC-Ola-086588 Oryzias latipes 75.12 0.00e+00 992.00
IUUC-Oga-088982 Otolemur garnettii 97.35 0.00e+00 1316.00
IUUC-Oar-090409 Ovis aries 97.35 0.00e+00 1294.00
IUUC-Ptr-091365 Pan troglodytes 96.73 0.00e+00 1274.00
IUUC-Pan-092753 Papio anubis 97.04 0.00e+00 1277.00
IUUC-Pma-094393 Petromyzon marinus 71.49 1.00e-88 318.00
IUUC-Pfo-096772 Poecilia formosa 76.05 0.00e+00 1009.00
IUUC-Pab-098516 Pongo abelii 97.20 0.00e+00 1278.00
IUUC-Pca-100604 Procavia capensis 87.46 0.00e+00 1137.00
IUUC-Pva-102388 Pteropus vampyrus 96.57 0.00e+00 1273.00
IUUC-Rno-105464 Rattus norvegicus 99.22 0.00e+00 1305.00
IUUC-Sha-107436 Sarcophilus harrisii 94.42 0.00e+00 1274.00
IUUC-Tgu-116590 Taeniopygia guttata 85.51 0.00e+00 1141.00
IUUC-Tru-117699 Takifugu rubripes 77.12 0.00e+00 1048.00
IUUC-Tsy-119465 Tarsius syrichta 95.95 0.00e+00 1265.00
IUUC-Tni-120314 Tetraodon nigroviridis 76.02 0.00e+00 1030.00
IUUC-Tbe-127336 Tupaia belangeri 94.86 0.00e+00 1219.00
IUUC-Ttr-128624 Tursiops truncatus 90.03 0.00e+00 1135.00
IUUC-Vpa-130453 Vicugna pacos 97.35 0.00e+00 1248.00
IUUC-Xtr-132900 Xenopus tropicalis 78.40 0.00e+00 1059.00
IUUC-Xma-133881 Xiphophorus maculatus 74.96 0.00e+00 1000.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved