iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061855

UUCD1 version

UUC-MoD-00542

Ensembl Protein ID

ENSMODP00000009683.3

UniProt Accession

F7A8H9; F7A8H9_MONDO

Protein Name

Uncharacterized protein

Gene Name

NEDD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007794.3	ENSMODT00000009874.3	ENSMODP00000009683.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-20	71.9	81	111
UBD/Beta-Prp	2.70e-40	138.5	81	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           tc+++ s+  +lvsG+ D+t+ +WDl++ +l
   Q: 81   TCINLnSTsMYLVSGGLDNTVNIWDLKSKRL 111
           79999866699***************98776 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstg.kcvhtlkghedsvlsls 101
           tc+     + +l++g+ d+t+ +wd++++ l rsl++h++evt+v+f+ ++ + ++gs  + i + ++ t+ + +   +g+ +s++ l+
   Q: 81   TCINLNSTSMYLVSGGLDNTVNIWDLKSKRLHRSLKDHKDEVTCVTFNWNDCYTASGSLSGEIILHSITTNlSSTPFGHGNGQSIRQLK 169
           6777888899****************************************99*************99986515555556999******* PP
   S: 102  fsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
           +s  +++ l s s+  ++ +wd+++++ +++++  h++  ++++++p +  llv+ +lD+ + l+d +++ +l+tl    + + + ++f
   Q: 170  YSLfKKSLLGSVSDNGVVTLWDVNSQSAYHNFDCSHKAPASGIAFSPVNdMLLVTIGLDKRIVLYDTASKIMLKTLV--TEAPLTAVDF 256
           ***7778999***************************************9**************************5..59******** PP
   S: 189  dsngkelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsg 240
            ++g  l+ gs  g++  +dl+  ++ v++  +h++ v+++ f       +s 
   Q: 257  MPDGATLAIGSSRGKIYQYDLRmLNSPVKIISAHKTSVQCITFQ--CSSALSK 307
           **********************97778**************998..5444444 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MQESIKFASA GDDVKIWDSS SMTMVEQFNP HSSSLGISSL CWSSNNNFLV TASASGDKIV 60
ISSCKCKPVP LLELAEGQKQ TCINLNSTSM YLVSGGLDNT VNIWDLKSKR LHRSLKDHKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGCCCTT CGTGACCTAC TGAACCCGAT CACCTCTGAC ATACAGGACC CAGTGCCTGT 60
GACCGACCCG TTCCCACCTT GGTTACGTCA GTACCACGCA TGCACGCTCC CCCCTCTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0045177--C:apical part of cell
GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000242--C:pericentriolar material
GO:0000922--C:spindle pole
GO:0071539--P:protein localization to centrosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000871	Aegilops tauschii	37.84	6.00e-17	83.20
IUUC-Aml-002397	Ailuropoda melanoleuca	72.73	0.00e+00	960.00
IUUC-Atr-002464	Amborella trichopoda	31.83	3.00e-38	153.00
IUUC-Apl-003870	Anas platyrhynchos	62.48	0.00e+00	822.00
IUUC-Aca-004925	Anolis carolinensis	59.19	0.00e+00	761.00
IUUC-Aly-005931	Arabidopsis lyrata	32.36	2.00e-38	154.00
IUUC-Ath-006681	Arabidopsis thaliana	32.36	2.00e-38	154.00
IUUC-Ame-010906	Astyanax mexicanus	64.90	2.00e-114	406.00
IUUC-Bta-013389	Bos taurus	73.62	0.00e+00	979.00
IUUC-Bdi-014340	Brachypodium distachyon	31.61	3.00e-38	153.00
IUUC-Bol-015773	Brassica oleracea	28.64	6.00e-38	152.00
IUUC-Bra-016623	Brassica rapa	29.19	3.00e-38	154.00
IUUC-Cja-019541	Callithrix jacchus	73.17	0.00e+00	989.00
IUUC-Cfa-021218	Canis familiaris	71.83	0.00e+00	946.00
IUUC-Cpo-021697	Cavia porcellus	68.45	0.00e+00	919.00
IUUC-Csa-023620	Chlorocebus sabaeus	73.03	0.00e+00	999.00
IUUC-Cho-025105	Choloepus hoffmanni	69.73	0.00e+00	744.00
IUUC-Cin-025293	Ciona intestinalis	40.47	3.00e-63	236.00
IUUC-Csv-026234	Ciona savignyi	36.64	5.00e-52	197.00
IUUC-Dre-028251	Danio rerio	64.55	5.00e-107	382.00
IUUC-Dno-029281	Dasypus novemcinctus	71.71	0.00e+00	794.00
IUUC-Dor-031020	Dipodomys ordii	56.84	3.00e-125	442.00
IUUC-Ete-033113	Echinops telfairi	74.23	5.00e-169	587.00
IUUC-Eca-034230	Equus caballus	73.36	0.00e+00	959.00
IUUC-Eeu-034671	Erinaceus europaeus	59.51	1.00e-179	622.00
IUUC-Fca-035775	Felis catus	74.07	0.00e+00	989.00
IUUC-Fal-037557	Ficedula albicollis	60.35	0.00e+00	744.00
IUUC-Gmo-038586	Gadus morhua	58.84	9.00e-106	377.00
IUUC-Gga-040153	Gallus gallus	62.48	0.00e+00	823.00
IUUC-Gac-041385	Gasterosteus aculeatus	49.53	1.00e-110	393.00
IUUC-Gma-042844	Glycine max	33.55	2.00e-42	167.00
IUUC-Ggo-044576	Gorilla gorilla	73.77	0.00e+00	1019.00
IUUC-Hsa-046198	Homo sapiens	73.62	0.00e+00	1018.00
IUUC-Hvu-047794	Hordeum vulgare	37.84	2.00e-17	82.00
IUUC-Lch-050561	Latimeria chalumnae	50.07	2.00e-159	555.00
IUUC-Lpe-051469	Leersia perrieri	32.57	3.00e-37	150.00
IUUC-Loc-052816	Lepisosteus oculatus	57.21	1.00e-122	434.00
IUUC-Laf-053880	Loxodonta africana	73.21	0.00e+00	931.00
IUUC-Mcc-054977	Macaca mulatta	73.17	0.00e+00	1000.00
IUUC-Meu-056141	Macropus eugenii	72.83	0.00e+00	735.00
IUUC-Mtr-058441	Medicago truncatula	32.92	1.00e-41	165.00
IUUC-Mga-060141	Meleagris gallopavo	61.42	0.00e+00	795.00
IUUC-Mmr-061201	Microcebus murinus	73.03	0.00e+00	1001.00
IUUC-Mmu-064342	Mus musculus	70.04	0.00e+00	932.00
IUUC-Mac-065368	Musa acuminata	32.12	1.00e-37	151.00
IUUC-Mpu-066191	Mustela putorius furo	72.43	0.00e+00	959.00
IUUC-Mlu-067310	Myotis lucifugus	72.92	0.00e+00	940.00
IUUC-Nle-069990	Nomascus leucogenys	73.62	0.00e+00	1019.00
IUUC-Opr-070336	Ochotona princeps	66.47	0.00e+00	841.00
IUUC-Ont-071675	Oreochromis niloticus	42.21	8.00e-139	487.00
IUUC-Oan-072772	Ornithorhynchus anatinus	69.42	0.00e+00	769.00
IUUC-Ocu-074095	Oryctolagus cuniculus	74.07	0.00e+00	989.00
IUUC-Oba-075327	Oryza barthii	32.24	2.00e-37	150.00
IUUC-Obr-076119	Oryza brachyantha	32.57	7.00e-38	152.00
IUUC-Ogl-077820	Oryza glaberrima	32.24	8.00e-37	149.00
IUUC-Ogu-078679	Oryza glumaepatula	32.57	3.00e-37	150.00
IUUC-Oin-079891	Oryza indica	32.24	2.00e-37	151.00
IUUC-Olo-080414	Oryza longistaminata	35.19	1.00e-36	148.00
IUUC-Ome-081888	Oryza meridionalis	32.89	1.00e-37	151.00
IUUC-Oni-082417	Oryza nivara	32.24	2.00e-37	150.00
IUUC-Opu-083393	Oryza punctata	32.57	1.00e-37	151.00
IUUC-Oru-084698	Oryza rufipogon	32.57	1.00e-37	152.00
IUUC-Osa-086121	Oryza sativa	32.24	2.00e-37	150.00
IUUC-Ola-086806	Oryzias latipes	41.42	3.00e-140	492.00
IUUC-Olu-087591	Ostreococcus lucimarinus	23.13	3.00e-15	76.30
IUUC-Oga-088622	Otolemur garnettii	73.62	0.00e+00	994.00
IUUC-Oar-090391	Ovis aries	70.72	0.00e+00	827.00
IUUC-Ptr-091036	Pan troglodytes	73.47	0.00e+00	1014.00
IUUC-Pan-092576	Papio anubis	73.03	0.00e+00	999.00
IUUC-Psi-093450	Pelodiscus sinensis	65.54	0.00e+00	835.00
IUUC-Pma-094101	Petromyzon marinus	53.05	1.00e-102	365.00
IUUC-Ppa-095262	Physcomitrella patens	32.48	6.00e-40	159.00
IUUC-Pfo-097142	Poecilia formosa	47.80	1.00e-111	397.00
IUUC-Pab-097829	Pongo abelii	73.77	0.00e+00	1021.00
IUUC-Pop-099687	Populus trichocarpa	33.66	2.00e-41	164.00
IUUC-Pca-100217	Procavia capensis	70.74	7.00e-170	590.00
IUUC-Ppe-101502	Prunus persica	33.66	6.00e-42	166.00
IUUC-Pva-102736	Pteropus vampyrus	70.79	0.00e+00	961.00
IUUC-Rno-104977	Rattus norvegicus	70.04	0.00e+00	898.00
IUUC-Sha-107003	Sarcophilus harrisii	88.66	0.00e+00	1177.00
IUUC-Smo-108734	Selaginella moellendorffii	30.85	1.00e-37	150.00
IUUC-Sit-109796	Setaria italica	32.67	7.00e-38	152.00
IUUC-Sly-110941	Solanum lycopersicum	31.17	8.00e-39	155.00
IUUC-Stu-112314	Solanum tuberosum	32.47	2.00e-39	157.00
IUUC-Sar-112926	Sorex araneus	66.47	0.00e+00	867.00
IUUC-Sbi-113822	Sorghum bicolor	34.29	9.00e-28	118.00
IUUC-Ssc-116242	Sus scrofa	78.82	4.00e-166	577.00
IUUC-Tgu-116765	Taeniopygia guttata	61.58	0.00e+00	779.00
IUUC-Tru-117738	Takifugu rubripes	42.78	1.00e-148	520.00
IUUC-Tsy-118856	Tarsius syrichta	72.25	0.00e+00	902.00
IUUC-Tni-120871	Tetraodon nigroviridis	43.81	7.00e-149	520.00
IUUC-Tca-120965	Theobroma cacao	31.68	2.00e-38	154.00
IUUC-Tae-124830	Triticum aestivum	31.60	4.00e-38	153.00
IUUC-Tur-126840	Triticum urartu	31.60	4.00e-38	153.00
IUUC-Ttr-128551	Tursiops truncatus	71.24	0.00e+00	935.00
IUUC-Vpa-130324	Vicugna pacos	74.52	0.00e+00	962.00
IUUC-Vvi-131699	Vitis vinifera	33.33	8.00e-41	162.00
IUUC-Xtr-131956	Xenopus tropicalis	60.21	0.00e+00	806.00
IUUC-Xma-132982	Xiphophorus maculatus	47.58	7.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence