iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Smo-109099

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-protein ligase, UPL5

Genbank Nucleotide ID

GL377620

Gene Name

UPL5-1; SELMODRAFT_117305

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_117305	EFJ16195	EFJ16195

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-93	314.1	474	808
ULD/UDP/UBQ/UBQ_Other	8.70e-10	39.0	17	90

Active Site

Position(s)	Description	Evidence
776	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkk 104
           +++  l vef+ Ee+++  Gv re++++++ke++np+  lfl  +nd++ ++pnp+sg+ np hl +F+f Gr++++a++++  +d++++ +f+k+l g +
   Q: 474  NIQGGLSVEFSSEEATGP-GVLREWFFMVCKEIFNPQFALFLPCPNDRRRFYPNPASGV-NPGHLTYFKFCGRVIALAMMHRVQVDVTFALFFFKQLAGLP 572
           5677899**********9.***************************************9.89*************************************** PP
   S: 105  lsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple. 204
           +++ed  + dp ly s k i+e++ ++i+  +l ltf ++ e+lg++k+ eL+pgG+++ Vt +N++ +v+l+v+ rl   ++ qv+ f++Gf+++++ + 
   Q: 573  ITWEDSRDADPALYASCKNILEMDPDSIDSDTLGLTFVTEMELLGSRKVLELCPGGKDMAVTSTNRRHFVDLMVQRRLVAAVADQVKWFSQGFSDLLSNTs 673
           ************************99**********************************************************************98762 PP
   S: 205  ...llslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPs 300
              +l+ ++ e+l+l++ G+ +ei+ved+k++t+y ++yt+++++ +wFwev+ee+s e r+++L F+T+   lP++Gfa l  ++f i+k  ++ ++lP+
   Q: 674  ihqFLRPLDLEDLDLMLYGKdREISVEDWKQHTEY-HDYTASDEQARWFWEVVEEMSPERRRKLLFFATSVTHLPPEGFAGLT-SKFHIHKsLTNVTWLPT 772
           1125666799**********9**************.66*********************************************.77*****55555***** PP
   S: 301  snTCfnyLkLPeYsskeilkekL..lyAieetkgFe 334
           ++TCf++L LP+Yss +++++ L  ++A + ++gF+
   Q: 773  AHTCFYQLILPPYSSFDVMHRSLyaITADHIAEGFG 808
           ********************9994333333346666 PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksl.dgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           q++vk++ dg++  l+   sdt+  + ++i  ++g+p  +qrLi+ G+ L+ d++L  ++++++ t+hl+ +++
   Q: 17   QFFVKTYiDGKTIVLHATASDTIESVHQQILVRTGLPLLEQRLIFGGRQLQHDQSLETCHVTNDATLHLVARMR 90
           5667766255588889999***************************************************9986 PP

Organism

Selaginella moellendorffii

Protein Sequence
(Fasta)

MEVDRGVSCP SSSSHLQFFV KTYIDGKTIV LHATASDTIE SVHQQILVRT GLPLLEQRLI 60
FGGRQLQHDQ SLETCHVTND ATLHLVARMR STALPHSWQL INDLVATIRK MYGLSGDEVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGTGG ACAGGGGCGT TTCGTGCCCG AGTTCCTCGT CACATCTCCA GTTCTTTGTC 60
AAGACGTACA TTGATGGCAA GACGATTGTT CTTCACGCGA CAGCGTCGGA CACGATCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

smo:SELMODRAFT_117305

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000327	Aegilops tauschii	37.66	8.00e-116	410.00
IUUC-Atr-002891	Amborella trichopoda	44.43	0.00e+00	642.00
IUUC-Aly-005570	Arabidopsis lyrata	39.63	9.00e-156	543.00
IUUC-Ath-007126	Arabidopsis thaliana	40.17	2.00e-158	552.00
IUUC-Bdi-014613	Brachypodium distachyon	37.01	3.00e-131	462.00
IUUC-Gma-043346	Glycine max	44.54	0.00e+00	633.00
IUUC-Lpe-051617	Leersia perrieri	36.69	1.00e-125	443.00
IUUC-Ogl-077892	Oryza glaberrima	36.16	2.00e-106	379.00
IUUC-Ogu-078711	Oryza glumaepatula	36.93	3.00e-113	402.00
IUUC-Oin-079504	Oryza indica	35.67	1.00e-106	380.00
IUUC-Olo-080730	Oryza longistaminata	38.82	3.00e-109	388.00
IUUC-Ome-081851	Oryza meridionalis	36.86	9.00e-115	407.00
IUUC-Oni-082230	Oryza nivara	36.93	8.00e-113	400.00
IUUC-Opu-084015	Oryza punctata	36.53	3.00e-115	408.00
IUUC-Oru-084327	Oryza rufipogon	36.93	3.00e-113	402.00
IUUC-Osa-086148	Oryza sativa	35.06	2.00e-106	379.00
IUUC-Ppa-095337	Physcomitrella patens	62.63	0.00e+00	1038.00
IUUC-Pop-099556	Populus trichocarpa	39.18	2.00e-151	528.00
IUUC-Ppe-101443	Prunus persica	43.28	7.00e-177	613.00
IUUC-Sit-110651	Setaria italica	35.42	4.00e-125	441.00
IUUC-Sly-111513	Solanum lycopersicum	42.20	4.00e-175	607.00
IUUC-Stu-112582	Solanum tuberosum	42.26	9.00e-176	609.00
IUUC-Tca-121392	Theobroma cacao	43.35	0.00e+00	650.00
IUUC-Tur-126774	Triticum urartu	40.09	5.00e-121	427.00
IUUC-Vvi-131149	Vitis vinifera	41.97	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence