iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041041

UUCD1 version

UUC-GaG-00895

Ensembl Protein ID

ENSGALP00000046640.1

UniProt Accession

A0A1D5P1U8; A0A1D5P1U8_CHICK

Genbank Protein ID

ENSGALP00000046640

Protein Name

Ubiquitin carboxyl-terminal hydrolase 48

Genbank Nucleotide ID

AADN04000551

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000030857.1	ENSGALT00000061163.1	ENSGALP00000046640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-73	248.8	89	417
ULD/UDP/UBQ/UBQ_Other	7.00e-11	42.2	947	1005

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee 83
           +Gl+Nlg+tCY+N  LQ+ +   elr++l           e++++ +++ + ++++++lq lf+ l++sk+++++p+ ++kal+     
   Q: 89   VGLTNLGATCYVNTFLQMWFLNLELRQALYLcssnehAAGESIPK-DKDYEPQTICEHLQYLFALLQNSKRRYIDPSGFVKALG----- 171
           6***************************99975554322233333.3366777******************************9..... PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f++l
   Q: 172  LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLVSKFYEL 237
           78899*******************.......................457889999********************************* PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+++g++     +l+dc+ +f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + Ld+
   Q: 238  ELNIQGHK-----QLTDCITEFLKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELLDM 321
           ********.....9**********************************************************************99*** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg..................... 327
           +pf+++++      + YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +                     
   Q: 322  EPFMEQKNG----VYVYELSAVLIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkgth 406
           ******553....79**************************55555************9999998665999****************** PP
   S: 328  ..staYvlfYk 336
             ++aY+l+Y+
   Q: 407  csRNAYMLVYR 417
           **********8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 17   vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           v+   t +eLK +i +++++ p +q+L+++GkiL +d  tL+++g+ ++s+i+l  +++
   Q: 947  VSANQTLKELKIQIMHAFSVAPFDQNLLIDGKILsDDTATLGSLGIIPESVILLKADEP 1005
           88899************************************************988775 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWTETVPP EAVTQEHIEA AYRVGLEPCQ RGTCRRNCRG NPNCLVGIGE 60
HVWLGEIDEN SFHNIDDPNC ERRKKNAFVG LTNLGATCYV NTFLQMWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCACCGGCC CTGACGGCAG CGGGAGGGGC TGGGTCGGGC CGGGGGCGGC GATGGCGCCG 60
CGGCTGCAGT TAGAGAAGGC GGCCTGGCGC TGGACCGAGA CGGTGCCGCC CGAGGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	29.01	3.00e-82	300.00
IUUC-Aml-001357	Ailuropoda melanoleuca	86.71	0.00e+00	1814.00
IUUC-Atr-002976	Amborella trichopoda	31.90	3.00e-78	286.00
IUUC-Apl-003773	Anas platyrhynchos	96.65	0.00e+00	1835.00
IUUC-Aca-004466	Anolis carolinensis	84.33	0.00e+00	909.00
IUUC-Aly-006249	Arabidopsis lyrata	30.38	4.00e-72	266.00
IUUC-Ath-006700	Arabidopsis thaliana	31.32	4.00e-80	293.00
IUUC-Ame-011554	Astyanax mexicanus	68.27	0.00e+00	1433.00
IUUC-Bta-012573	Bos taurus	86.62	0.00e+00	1820.00
IUUC-Bdi-014149	Brachypodium distachyon	32.74	2.00e-81	296.00
IUUC-Bol-016289	Brassica oleracea	29.74	5.00e-81	296.00
IUUC-Bra-017494	Brassica rapa	32.64	2.00e-83	304.00
IUUC-Cel-018662	Caenorhabditis elegans	28.57	2.00e-31	131.00
IUUC-Cja-019991	Callithrix jacchus	85.82	0.00e+00	1815.00
IUUC-Cfa-020294	Canis familiaris	86.89	0.00e+00	1845.00
IUUC-Cpo-021706	Cavia porcellus	85.50	0.00e+00	1731.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	31.03	1.00e-42	169.00
IUUC-Csa-023931	Chlorocebus sabaeus	86.69	0.00e+00	1827.00
IUUC-Cho-024566	Choloepus hoffmanni	87.00	1.00e-138	487.00
IUUC-Cin-025307	Ciona intestinalis	47.99	1.00e-76	279.00
IUUC-Csv-026006	Ciona savignyi	36.39	1.00e-152	533.00
IUUC-Cne-027065	Cryptococcus neoformans	27.43	1.00e-67	251.00
IUUC-Dre-027624	Danio rerio	69.24	0.00e+00	1474.00
IUUC-Dno-029633	Dasypus novemcinctus	87.87	0.00e+00	1187.00
IUUC-Dor-030809	Dipodomys ordii	66.88	0.00e+00	1062.00
IUUC-Ete-032818	Echinops telfairi	83.00	0.00e+00	857.00
IUUC-Eca-033692	Equus caballus	87.17	0.00e+00	1836.00
IUUC-Eeu-035185	Erinaceus europaeus	67.21	0.00e+00	696.00
IUUC-Fca-035676	Felis catus	86.68	0.00e+00	1841.00
IUUC-Fal-036913	Ficedula albicollis	95.74	0.00e+00	1992.00
IUUC-Gmo-038532	Gadus morhua	65.03	0.00e+00	1388.00
IUUC-Gac-042570	Gasterosteus aculeatus	66.54	0.00e+00	1435.00
IUUC-Gma-044136	Glycine max	29.83	2.00e-91	330.00
IUUC-Ggo-045367	Gorilla gorilla	82.60	0.00e+00	1706.00
IUUC-Hsa-046019	Homo sapiens	86.98	0.00e+00	1830.00
IUUC-Hvu-047303	Hordeum vulgare	33.64	2.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	84.75	0.00e+00	1805.00
IUUC-Lch-049989	Latimeria chalumnae	76.77	0.00e+00	1632.00
IUUC-Lpe-051612	Leersia perrieri	32.65	4.00e-79	289.00
IUUC-Loc-052756	Lepisosteus oculatus	70.84	0.00e+00	1529.00
IUUC-Laf-054043	Loxodonta africana	85.78	0.00e+00	1822.00
IUUC-Mcc-054986	Macaca mulatta	85.36	0.00e+00	1807.00
IUUC-Meu-056228	Macropus eugenii	71.84	0.00e+00	790.00
IUUC-Mtr-058610	Medicago truncatula	30.01	1.00e-81	297.00
IUUC-Mga-059896	Meleagris gallopavo	97.90	0.00e+00	1937.00
IUUC-Mvi-060269	Microbotryum violaceum	36.99	5.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	86.98	0.00e+00	1826.00
IUUC-Mdo-062506	Monodelphis domestica	87.56	0.00e+00	1847.00
IUUC-Mmu-063642	Mus musculus	83.51	0.00e+00	1780.00
IUUC-Mac-064896	Musa acuminata	31.68	2.00e-78	287.00
IUUC-Mpu-066194	Mustela putorius furo	86.98	0.00e+00	1827.00
IUUC-Mlu-067233	Myotis lucifugus	86.42	0.00e+00	1821.00
IUUC-Nle-069052	Nomascus leucogenys	85.70	0.00e+00	1811.00
IUUC-Opr-070890	Ochotona princeps	85.08	0.00e+00	1113.00
IUUC-Ont-071450	Oreochromis niloticus	65.18	0.00e+00	1386.00
IUUC-Oan-073252	Ornithorhynchus anatinus	85.49	0.00e+00	996.00
IUUC-Ocu-073796	Oryctolagus cuniculus	86.78	0.00e+00	1581.00
IUUC-Oba-075563	Oryza barthii	33.67	6.00e-80	292.00
IUUC-Obr-076394	Oryza brachyantha	31.70	8.00e-79	288.00
IUUC-Ogl-077339	Oryza glaberrima	39.04	1.00e-40	159.00
IUUC-Ogu-079007	Oryza glumaepatula	34.51	1.00e-74	275.00
IUUC-Oin-079997	Oryza indica	33.67	3.00e-80	293.00
IUUC-Olo-080364	Oryza longistaminata	34.29	6.00e-80	292.00
IUUC-Ome-081165	Oryza meridionalis	33.86	1.00e-74	275.00
IUUC-Oni-083026	Oryza nivara	33.67	4.00e-80	293.00
IUUC-Opu-083284	Oryza punctata	35.36	3.00e-75	276.00
IUUC-Oru-084797	Oryza rufipogon	33.67	4.00e-80	293.00
IUUC-Osa-086221	Oryza sativa	39.04	1.00e-40	159.00
IUUC-Ola-086568	Oryzias latipes	67.29	0.00e+00	1449.00
IUUC-Oga-088687	Otolemur garnettii	85.81	0.00e+00	1816.00
IUUC-Oar-090345	Ovis aries	87.14	0.00e+00	1746.00
IUUC-Ptr-090734	Pan troglodytes	86.89	0.00e+00	1828.00
IUUC-Pan-091704	Papio anubis	83.57	0.00e+00	1737.00
IUUC-Psi-092937	Pelodiscus sinensis	92.46	0.00e+00	1694.00
IUUC-Ppa-095808	Physcomitrella patens	28.37	5.00e-70	259.00
IUUC-Pab-098129	Pongo abelii	86.89	0.00e+00	1828.00
IUUC-Pop-099494	Populus trichocarpa	30.60	9.00e-79	288.00
IUUC-Pca-100647	Procavia capensis	88.79	1.00e-180	626.00
IUUC-Ppe-102091	Prunus persica	29.38	5.00e-82	299.00
IUUC-Pva-102719	Pteropus vampyrus	86.69	0.00e+00	1817.00
IUUC-Rno-105363	Rattus norvegicus	85.34	0.00e+00	1809.00
IUUC-Sha-107620	Sarcophilus harrisii	85.04	0.00e+00	1729.00
IUUC-Smo-109487	Selaginella moellendorffii	27.80	1.00e-82	301.00
IUUC-Sit-110683	Setaria italica	29.91	3.00e-80	293.00
IUUC-Sly-111377	Solanum lycopersicum	29.66	1.00e-78	287.00
IUUC-Stu-111969	Solanum tuberosum	32.19	1.00e-69	257.00
IUUC-Sar-113099	Sorex araneus	87.21	0.00e+00	1578.00
IUUC-Sbi-113833	Sorghum bicolor	43.10	1.00e-56	212.00
IUUC-Ssc-115279	Sus scrofa	80.03	0.00e+00	1186.00
IUUC-Tgu-117519	Taeniopygia guttata	92.17	0.00e+00	1810.00
IUUC-Tru-117651	Takifugu rubripes	67.26	0.00e+00	1433.00
IUUC-Tsy-119201	Tarsius syrichta	84.86	0.00e+00	1644.00
IUUC-Tni-120840	Tetraodon nigroviridis	68.26	0.00e+00	1454.00
IUUC-Tca-121674	Theobroma cacao	30.80	2.00e-84	306.00
IUUC-Tae-125247	Triticum aestivum	29.15	3.00e-83	303.00
IUUC-Tur-126599	Triticum urartu	30.31	2.00e-81	297.00
IUUC-Tbe-127782	Tupaia belangeri	76.70	0.00e+00	1545.00
IUUC-Ttr-128312	Tursiops truncatus	85.44	0.00e+00	1791.00
IUUC-Vpa-130348	Vicugna pacos	87.10	0.00e+00	1746.00
IUUC-Vvi-131353	Vitis vinifera	32.56	6.00e-83	302.00
IUUC-Xtr-132172	Xenopus tropicalis	71.01	0.00e+00	1338.00
IUUC-Xma-133263	Xiphophorus maculatus	67.65	0.00e+00	1403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence