iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 2    svtnedlkcLeegeflnDviidfylkylvlekl..kkekverihifssffykklkqke..rr..rvktwtr....kvdlfekdlifvpineaaHWsla 89
           ++t + l+cL++g++lnD++i++y+  l++e+   + +k  ++h+f++ff++kl +++  ++  +v++wt      + l ++d if+pi+ + HW+la
   Q: 301  DITGKILRCLKPGKWLNDEVINLYMV-LLKEREarEPKKFLKCHFFNTFFFTKLVNSAtgYNygAVRRWTSmkrlGYHLKDCDKIFIPIHMNIHWTLA 397
           789999********************.777766578899***************9965335577******987888899******************* PP
   S: 90   vvcfkkksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk.vpqQkNssDCGvyvlqyve 162
           v+++k++++ +lDS  +  + +++++l++y  +ev++ks+ +++ +++++++++ +p Q+N++DCG+++++y++
   Q: 398  VINIKDQKFQYLDSF-KGREPKILDALARYFVDEVRDKSEVDLDVSRWRQEFVQdLPMQRNGFDCGMFMVKYID 470
           ***************.788999****************************99999*****************97 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, and very inefficiently of SUM3. Seems to be the only ULP1 able to cleave SUM3 precursors. Cleaves SUMO peptides better than SUMO-conjugated proteins.

Protein Sequence
(Fasta)

MKNQSRVLNS ELGDFDLSVL WDQILNFEGY GSYCFRPMDM DGYHKRSAGL NPCKHSGFSH 60
SSRPMAPGIY RYPEVKSSLR RQVHAPVRIL NSGRDRSTRQ GSGNVLGTFL TRNNDMWKRN 120

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Nucleotide Sequence
(Fasta)

AGGGTATGAG ATAAGTCAAC ATATTTGAGT TTGACCTATC TCTTCCAAAA CAAAACCCGC 60
CCGGGTCTCA TGTCCGGGTC CGAATCTGTG TATCGGAAAC GCCAGTGAGT TTAATGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0005634--C:nucleus
GO:0009506--C:plasmodesma
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0016926--P:protein desumoylation

KEGG

ath:AT3G06910

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001166	Aegilops tauschii	59.63	8.00e-80	289.00
IUUC-Aly-006429	Arabidopsis lyrata	89.46	0.00e+00	779.00
IUUC-Bol-015236	Brassica oleracea	65.05	6.00e-143	499.00
IUUC-Bra-018062	Brassica rapa	66.67	4.00e-144	503.00
IUUC-Cin-025277	Ciona intestinalis	38.30	4.00e-32	129.00
IUUC-Csv-026222	Ciona savignyi	38.81	2.00e-34	138.00
IUUC-Dre-027383	Danio rerio	38.98	3.00e-39	155.00
IUUC-Dse-031224	Dothistroma septosporum	26.63	6.00e-12	63.20
IUUC-Fox-037968	Fusarium oxysporum	26.77	5.00e-13	69.70
IUUC-Laf-053368	Loxodonta africana	39.80	2.00e-37	150.00
IUUC-Opr-070806	Ochotona princeps	38.81	1.00e-36	146.00
IUUC-Oba-075703	Oryza barthii	58.82	6.00e-84	303.00
IUUC-Ogl-077509	Oryza glaberrima	58.82	9.00e-84	303.00
IUUC-Ogu-078434	Oryza glumaepatula	58.82	4.00e-84	304.00
IUUC-Oin-080186	Oryza indica	58.82	1.00e-83	302.00
IUUC-Oni-082830	Oryza nivara	58.82	1.00e-83	302.00
IUUC-Oru-084475	Oryza rufipogon	58.82	1.00e-83	302.00
IUUC-Olu-087729	Ostreococcus lucimarinus	42.29	1.00e-46	178.00
IUUC-Ppa-095997	Physcomitrella patens	60.26	1.00e-86	313.00
IUUC-Pgr-103502	Puccinia graminis	36.52	1.00e-29	124.00
IUUC-Ptt-103854	Puccinia triticina	33.80	5.00e-07	47.80
IUUC-Pyt-104575	Pyrenophora triticirepentis	30.29	2.00e-15	77.00
IUUC-Sja-107906	Schizosaccharomyces japonicus	39.70	7.00e-38	150.00
IUUC-Spo-108221	Schizosaccharomyces pombe	36.82	7.00e-39	154.00
IUUC-Smo-108869	Selaginella moellendorffii	60.67	2.00e-80	290.00
IUUC-Ssc-115700	Sus scrofa	39.30	9.00e-37	147.00
IUUC-Vda-129779	Verticillium dahliae	27.23	4.00e-16	79.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence