iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004016

Ensembl Protein ID

ENSAPLP00000009324.1

UniProt Accession

U3IQ01; U3IQ01_ANAPL

Genbank Protein ID

ENSAPLP00000009324

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01016961

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000009512.1	ENSAPLT00000010014.1	ENSAPLP00000009324.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-22	78.6	294	328
UBD/Beta-Prp	1.30e-49	168.7	213	472

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrt 32
           Htd+v +++f    d  ++vsGs+Dgt ++W +++
   Q: 294  HTDKVVAVQFcnnGDsLRFVSGSRDGTARIWHYHQ 328
           ***********86335779************8765 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v+++
   Q: 213  TRYLTSTGADGTICFWQWHANTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKMAELESHTDKVVAV 301
           689***************997776677764444444444449************************88888****************** PP
   S: 101  sfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           +f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W+++tg+l
   Q: 302  QFCNNGdsLRFVSGSRDGTARIWHYHQQEWKSIvldmatkmtgnnvasgEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQL 390
           ****8832468*****************99999************8888888888899******************************* PP
   S: 172  lrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           l+ l+g h+d v  l+   fd+  + ++s+++dg + +wd+ +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 391  LHSLSG-HDDEVFVLEahpFDQ--RIVLSAGHDGNIFVWDIDKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 472
           *****9.*********554544..8999******************988877554555577777899999999999998887765 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

HIPPDYLLRI CERLGPLLDK EIPQSVLGVQ TLLGVGRQSL LRAAKDFRHT LWKGSAFAAL 60
HRGRPPELPV NYGKPPNVEN RLLATSLSKE EIITKPTFVL LQLQLSTPLK NLYKTQICIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACATCCCTC CGGATTATCT TCTTCGGATC TGCGAGAGGC TGGGACCGCT CTTAGACAAG 60
GAAATCCCTC AGAGTGTCCT AGGTGTGCAG ACCTTGCTAG GCGTTGGGCG GCAGTCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	80.61	0.00e+00	2241.00
IUUC-Aca-004722	Anolis carolinensis	86.33	0.00e+00	2187.00
IUUC-Ame-010602	Astyanax mexicanus	64.71	0.00e+00	1758.00
IUUC-Bta-013198	Bos taurus	81.60	0.00e+00	2117.00
IUUC-Cfa-020963	Canis familiaris	80.36	0.00e+00	2236.00
IUUC-Cpo-022448	Cavia porcellus	75.02	0.00e+00	2091.00
IUUC-Csa-023166	Chlorocebus sabaeus	80.08	0.00e+00	2226.00
IUUC-Cin-025553	Ciona intestinalis	42.31	5.00e-118	418.00
IUUC-Dre-028508	Danio rerio	65.14	0.00e+00	1720.00
IUUC-Dno-030070	Dasypus novemcinctus	79.50	0.00e+00	2204.00
IUUC-Dor-031052	Dipodomys ordii	80.26	0.00e+00	884.00
IUUC-Ete-032650	Echinops telfairi	75.68	0.00e+00	1479.00
IUUC-Eca-033953	Equus caballus	82.50	0.00e+00	2137.00
IUUC-Eeu-034871	Erinaceus europaeus	67.37	0.00e+00	1000.00
IUUC-Fca-036099	Felis catus	80.00	0.00e+00	2221.00
IUUC-Fal-037246	Ficedula albicollis	92.19	0.00e+00	2486.00
IUUC-Gmo-039116	Gadus morhua	66.18	2.00e-161	563.00
IUUC-Gga-041097	Gallus gallus	93.72	0.00e+00	2567.00
IUUC-Gac-042435	Gasterosteus aculeatus	62.57	0.00e+00	1668.00
IUUC-Hsa-045666	Homo sapiens	79.94	0.00e+00	2227.00
IUUC-Lch-050646	Latimeria chalumnae	61.95	0.00e+00	1736.00
IUUC-Loc-051802	Lepisosteus oculatus	69.71	0.00e+00	1902.00
IUUC-Laf-053942	Loxodonta africana	79.92	0.00e+00	2268.00
IUUC-Mcc-054645	Macaca mulatta	80.08	0.00e+00	2228.00
IUUC-Meu-056321	Macropus eugenii	67.65	0.00e+00	952.00
IUUC-Mga-060063	Meleagris gallopavo	91.65	0.00e+00	2527.00
IUUC-Mmr-061262	Microcebus murinus	80.21	0.00e+00	2254.00
IUUC-Mdo-062320	Monodelphis domestica	72.92	0.00e+00	1974.00
IUUC-Mmu-063163	Mus musculus	79.71	0.00e+00	2220.00
IUUC-Mpu-066628	Mustela putorius furo	80.47	0.00e+00	2239.00
IUUC-Mlu-068082	Myotis lucifugus	79.88	0.00e+00	2180.00
IUUC-Nle-069609	Nomascus leucogenys	80.08	0.00e+00	2236.00
IUUC-Ont-071589	Oreochromis niloticus	64.45	0.00e+00	1665.00
IUUC-Ocu-074122	Oryctolagus cuniculus	80.73	0.00e+00	1774.00
IUUC-Ogl-077493	Oryza glaberrima	29.94	9.00e-47	182.00
IUUC-Ogu-078641	Oryza glumaepatula	30.12	5.00e-45	176.00
IUUC-Oni-082991	Oryza nivara	29.84	4.00e-45	177.00
IUUC-Ola-086580	Oryzias latipes	63.65	0.00e+00	1690.00
IUUC-Oga-089053	Otolemur garnettii	80.35	0.00e+00	2236.00
IUUC-Oar-090042	Ovis aries	80.33	0.00e+00	2227.00
IUUC-Ptr-091268	Pan troglodytes	79.88	0.00e+00	2224.00
IUUC-Pan-092376	Papio anubis	80.08	0.00e+00	2228.00
IUUC-Psi-093408	Pelodiscus sinensis	86.83	0.00e+00	2439.00
IUUC-Pfo-096515	Poecilia formosa	63.88	0.00e+00	1627.00
IUUC-Pab-097672	Pongo abelii	78.19	0.00e+00	2179.00
IUUC-Pva-102512	Pteropus vampyrus	81.90	0.00e+00	1889.00
IUUC-Rno-105797	Rattus norvegicus	79.50	0.00e+00	2208.00
IUUC-Sha-107061	Sarcophilus harrisii	74.91	0.00e+00	2050.00
IUUC-Sar-113004	Sorex araneus	67.61	0.00e+00	1102.00
IUUC-Tgu-117254	Taeniopygia guttata	90.39	0.00e+00	2463.00
IUUC-Tru-118186	Takifugu rubripes	62.93	0.00e+00	1647.00
IUUC-Tsy-119003	Tarsius syrichta	75.36	0.00e+00	2034.00
IUUC-Tni-120110	Tetraodon nigroviridis	62.81	0.00e+00	1621.00
IUUC-Ttr-129265	Tursiops truncatus	79.78	0.00e+00	2215.00
IUUC-Vpa-130736	Vicugna pacos	73.42	0.00e+00	1067.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence