iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116195

Ensembl Protein ID

ENSSSCP00000021679.1

UniProt Accession

I3LCA5; I3LCA5_PIG

Protein Name

Uncharacterized protein

Gene Name

LOC100512752

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000022323.1	ENSSSCT00000031488.1	ENSSSCP00000021679.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-29	99.0	166	195
UBD/Beta-Prp	3.20e-62	210.7	3	200

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           Htd+v +++f ++ +++vsGs+Dgt ++W 
   Q: 166  HTDKVDSIQFsNTsNRFVSGSRDGTARIWQ 195
           9*********9667***************7 PP

UBD/Beta-Prp

   S: 28   gsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp....sgdklvsG 112
           gs+d  +k+w +++g ll++l gh ae++++  + +  +++ gs D++i+vw l+t+ ++ +l+gh++s++sl+fsp    s+ +l s+
   Q: 3    GSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPlcsgSKRYLSST 91
           89999*******************************99*****************************************877799**** PP
   S: 113  shdrtirvwdletgqclee......tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkl..lrtltgghtdsvyslsfdsng 192
           ++d ti  w ++ g+   +      t++++ gv ++ ++ + g   l++Gs+D ++r++   +g+   + +l+  htd+v s++f+ ++
   Q: 92   GADGTICFWLWDAGTLKINprpakfTERPRPGVQMICSSFSAGgMFLATGSTDHIIRVYFFGSGQPekISELEF-HTDKVDSIQFSNTS 179
           ********9888888887788************9988887777799*************996666511667788.************** PP
   S: 193  kelvsgsldgtvklwdlqtge 213
           +++vsgs+dgt ++w++++ e
   Q: 180  NRFVSGSRDGTARIWQFKRRE 200
           ****************99776 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

FKGSDDCLVK IWATDDGRLL ATLRGHAAEI SDMAVNYENT MIAAGSCDKM IRVWCLRTCA 60
PLAVLQGHSA SITSLQFSPL CSGSKRYLSS TGADGTICFW LWDAGTLKIN PRPAKFTERP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCAAAATT TATAGAGTTA ATTCTGTTAA TATCCATTTT TATTTTAAGG GTTCTGATGA 60
CTGTCTTGTG AAAATCTGGG CAACAGATGA TGGGAGATTA TTAGCTACTT TAAGAGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024794	Choloepus hoffmanni	90.32	0.00e+00	875.00
IUUC-Mga-060063	Meleagris gallopavo	55.75	0.00e+00	758.00
IUUC-Opr-070971	Ochotona princeps	69.41	0.00e+00	877.00
IUUC-Ogl-077493	Oryza glaberrima	26.93	1.00e-28	122.00
IUUC-Ogu-078641	Oryza glumaepatula	26.68	2.00e-28	122.00
IUUC-Oin-079669	Oryza indica	30.13	9.00e-47	181.00
IUUC-Olo-080755	Oryza longistaminata	30.67	1.00e-48	189.00
IUUC-Oni-082991	Oryza nivara	26.57	5.00e-34	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence