iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053915

Ensembl Protein ID

ENSLAFP00000004752.4

UniProt Accession

G3SWN7; G3SWN7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005663.4	ENSLAFT00000005662.4	ENSLAFP00000004752.4
ENSLAFG00000005663.4	ENSLAFT00000029336.1	ENSLAFP00000025230.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.06	0.00e+00	837.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 60
RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLQ CSPEQAVELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGTGCT ATGTAACGAG GCCGGACGCG GTGCTGATGG AGGTGGAGGT GGAGGCGAAA 60
GCCAACGGCG AGGACTGCCT CAACCAGTGA AGGGAGAGGG GNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019749--Band_41_domain
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF00373--FERM_M
PF09379--FERM_N

PRINTS

PR00935--BAND41
PR00661--ERMFAMILY

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0019898--C:extrinsic component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	93.75	0.00e+00	779.00
IUUC-Apl-003704	Anas platyrhynchos	89.50	0.00e+00	753.00
IUUC-Aca-004645	Anolis carolinensis	87.87	0.00e+00	748.00
IUUC-Ame-011401	Astyanax mexicanus	74.10	0.00e+00	646.00
IUUC-Bta-012752	Bos taurus	92.11	0.00e+00	692.00
IUUC-Cja-019734	Callithrix jacchus	94.38	0.00e+00	830.00
IUUC-Cfa-020145	Canis familiaris	93.68	0.00e+00	706.00
IUUC-Cpo-021436	Cavia porcellus	93.16	0.00e+00	702.00
IUUC-Csa-024248	Chlorocebus sabaeus	95.51	0.00e+00	840.00
IUUC-Cho-024528	Choloepus hoffmanni	83.15	0.00e+00	672.00
IUUC-Cin-025748	Ciona intestinalis	36.33	1.00e-47	183.00
IUUC-Csv-025837	Ciona savignyi	37.93	3.00e-89	322.00
IUUC-Dre-027847	Danio rerio	74.55	0.00e+00	650.00
IUUC-Dno-029860	Dasypus novemcinctus	94.21	0.00e+00	674.00
IUUC-Dor-030664	Dipodomys ordii	82.47	0.00e+00	686.00
IUUC-Dse-031509	Dothistroma septosporum	43.14	6.00e-09	56.20
IUUC-Dme-031990	Drosophila melanogaster	36.06	6.00e-28	119.00
IUUC-Ete-032496	Echinops telfairi	76.41	8.00e-147	513.00
IUUC-Eca-033674	Equus caballus	93.76	0.00e+00	843.00
IUUC-Eeu-035048	Erinaceus europaeus	84.94	0.00e+00	747.00
IUUC-Fca-036547	Felis catus	93.03	0.00e+00	780.00
IUUC-Fal-037504	Ficedula albicollis	89.93	0.00e+00	741.00
IUUC-Gmo-038660	Gadus morhua	73.82	8.00e-152	530.00
IUUC-Gga-040123	Gallus gallus	90.34	0.00e+00	789.00
IUUC-Gac-042073	Gasterosteus aculeatus	70.98	1.00e-179	622.00
IUUC-Ggo-045387	Gorilla gorilla	95.06	0.00e+00	836.00
IUUC-Hsa-046869	Homo sapiens	95.06	0.00e+00	839.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	92.58	0.00e+00	816.00
IUUC-Lch-049990	Latimeria chalumnae	80.00	0.00e+00	753.00
IUUC-Lpe-051271	Leersia perrieri	39.62	2.00e-07	53.90
IUUC-Loc-051908	Lepisosteus oculatus	74.33	0.00e+00	653.00
IUUC-Mcc-054865	Macaca mulatta	95.28	0.00e+00	838.00
IUUC-Meu-056826	Macropus eugenii	86.36	6.00e-75	274.00
IUUC-Mga-059827	Meleagris gallopavo	89.45	0.00e+00	711.00
IUUC-Mmr-060734	Microcebus murinus	95.06	0.00e+00	835.00
IUUC-Mdo-062988	Monodelphis domestica	92.81	0.00e+00	824.00
IUUC-Mmu-064415	Mus musculus	93.48	0.00e+00	790.00
IUUC-Mpu-066118	Mustela putorius furo	93.42	0.00e+00	699.00
IUUC-Mlu-067131	Myotis lucifugus	93.26	0.00e+00	803.00
IUUC-Nle-070112	Nomascus leucogenys	95.51	0.00e+00	837.00
IUUC-Opr-071193	Ochotona princeps	91.12	0.00e+00	773.00
IUUC-Ont-072635	Oreochromis niloticus	73.38	0.00e+00	637.00
IUUC-Oan-073266	Ornithorhynchus anatinus	89.18	0.00e+00	742.00
IUUC-Ocu-074903	Oryctolagus cuniculus	91.69	0.00e+00	802.00
IUUC-Ome-081491	Oryza meridionalis	39.62	2.00e-07	54.30
IUUC-Oni-082255	Oryza nivara	39.62	2.00e-07	54.30
IUUC-Osa-085816	Oryza sativa	39.62	3.00e-08	52.40
IUUC-Ola-087533	Oryzias latipes	71.59	2.00e-176	611.00
IUUC-Oga-087979	Otolemur garnettii	94.83	0.00e+00	842.00
IUUC-Oar-089747	Ovis aries	92.31	0.00e+00	763.00
IUUC-Ptr-090732	Pan troglodytes	95.28	0.00e+00	837.00
IUUC-Pan-092032	Papio anubis	95.51	0.00e+00	840.00
IUUC-Psi-093296	Pelodiscus sinensis	89.74	0.00e+00	754.00
IUUC-Pma-094351	Petromyzon marinus	51.41	2.00e-32	131.00
IUUC-Pfo-097183	Poecilia formosa	73.29	8.00e-174	603.00
IUUC-Pab-098177	Pongo abelii	94.83	0.00e+00	835.00
IUUC-Pca-100734	Procavia capensis	95.06	0.00e+00	842.00
IUUC-Pva-102778	Pteropus vampyrus	95.43	0.00e+00	796.00
IUUC-Rno-106039	Rattus norvegicus	93.26	0.00e+00	818.00
IUUC-Sha-106869	Sarcophilus harrisii	92.31	0.00e+00	764.00
IUUC-Sar-113587	Sorex araneus	63.22	7.00e-138	483.00
IUUC-Ssc-116212	Sus scrofa	94.16	0.00e+00	821.00
IUUC-Tgu-116871	Taeniopygia guttata	89.69	0.00e+00	739.00
IUUC-Tru-117925	Takifugu rubripes	72.48	0.00e+00	657.00
IUUC-Tsy-118815	Tarsius syrichta	93.27	0.00e+00	758.00
IUUC-Tni-120007	Tetraodon nigroviridis	72.30	0.00e+00	630.00
IUUC-Tbe-127381	Tupaia belangeri	91.76	0.00e+00	631.00
IUUC-Ttr-129025	Tursiops truncatus	79.81	8.00e-179	619.00
IUUC-Vpa-130164	Vicugna pacos	70.56	9.00e-150	522.00
IUUC-Xtr-132800	Xenopus tropicalis	81.57	0.00e+00	719.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence