iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007638

Ensembl Protein ID

AT2G46500.2

UniProt Accession

Q9ZPY9; B9DGU3; B9DHV3; P4KG4_ARATH

Genbank Protein ID

AAD20161.1; AAM15268.1; AEC10708.1; AEC10709.1; AAL31898.1; AAO11610.1; BAH19960.1; BAH20320.1

Protein Name

Phosphatidylinositol 4-kinase gamma 4; Ubiquitin-like domain kinase gamma 4

Genbank Nucleotide ID

AC006418; AC006526; CP002685; CP002685; AF419566; BT002694; AK317284; AK317659

Gene Name

PI4KG4; PI4KGAMMA4; UBDKGAMMA4; At2g46500; F11C10.19; F13A10.3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G46500	AT2G46500.3	AT2G46500.3
AT2G46500	AT2G46500.2	AT2G46500.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
ULD/UDP/UFD/MUB	MUB	17880284; 25320573

Classification

Family	E-value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	9.70e-36	122.4	113	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 3    ltvktlkgkefelevseddtveelKekiakesg..vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           l vkt++gk+++++v++ +++  +K++i+k++g  v+p++q+++y+G++L+D++ +++++ +d+sv+hl+v++s 
   Q: 113  LDVKTTCGKHCRFHVERGRNIGYVKKQISKKRGdfVDPDEQEILYEGEKLEDQSLINDICRNDDSVLHLLVRRSA 187
           78**********************************************************************985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) (By similarity). Undergoes autophosphorylation and phosphorylates serine/threonine residues of protein substrates. Phosphorylates RPN10 and UFD1 in vitro.

Protein Sequence
(Fasta)

MSSAGVALSP VRSEPLIMPL VRANSCLDSY PDDTIMIYLT LPGSVIPMRV LESDSIESVK 60
LRIQSYRGFV VRNQKLVFGG RELARSNSNM RDYGVSEGNI LHLVLKLSDL QVLDVKTTCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACGGTGA AATAATGACG ATTAAAACCC CAAAGTCTCT GGCTTGGTTT CCACTCCAAG 60
GGTAAAATAC AAAACAAAAT CAACGAAACT GCCGTACACC GTTGACAATA AACAAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000403--PI3/4_kinase_cat_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00454--PI3_PI4_kinase
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0004430--F:1-phosphatidylinositol 4-kinase activity
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0046854--P:phosphatidylinositol phosphorylation
GO:0046777--P:protein autophosphorylation
GO:0009651--P:response to salt stress

KEGG

ath:AT2G46500

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001119	Aegilops tauschii	54.53	2.00e-173	601.00
IUUC-Atr-003173	Amborella trichopoda	60.72	0.00e+00	715.00
IUUC-Aly-006373	Arabidopsis lyrata	97.17	0.00e+00	1110.00
IUUC-Bdi-014830	Brachypodium distachyon	54.48	2.00e-177	615.00
IUUC-Bol-015291	Brassica oleracea	84.71	0.00e+00	957.00
IUUC-Hvu-047637	Hordeum vulgare	54.88	9.00e-177	612.00
IUUC-Lpe-051347	Leersia perrieri	54.29	2.00e-176	611.00
IUUC-Mtr-058430	Medicago truncatula	58.32	0.00e+00	684.00
IUUC-Mac-064878	Musa acuminata	52.90	5.00e-165	573.00
IUUC-Oba-075122	Oryza barthii	58.07	0.00e+00	635.00
IUUC-Obr-076735	Oryza brachyantha	57.90	2.00e-179	621.00
IUUC-Ogl-077728	Oryza glaberrima	58.07	0.00e+00	635.00
IUUC-Ogu-078710	Oryza glumaepatula	58.07	0.00e+00	633.00
IUUC-Oin-079877	Oryza indica	58.07	0.00e+00	633.00
IUUC-Olo-080554	Oryza longistaminata	54.80	2.00e-179	621.00
IUUC-Ome-081224	Oryza meridionalis	58.07	0.00e+00	632.00
IUUC-Oni-082355	Oryza nivara	58.07	0.00e+00	632.00
IUUC-Opu-083124	Oryza punctata	54.75	6.00e-180	623.00
IUUC-Oru-085036	Oryza rufipogon	58.07	0.00e+00	633.00
IUUC-Osa-085868	Oryza sativa	58.07	0.00e+00	633.00
IUUC-Olu-087862	Ostreococcus lucimarinus	47.89	7.00e-68	249.00
IUUC-Ppa-095406	Physcomitrella patens	47.93	2.00e-149	521.00
IUUC-Pop-098893	Populus trichocarpa	64.70	0.00e+00	784.00
IUUC-Smo-109415	Selaginella moellendorffii	49.43	2.00e-145	508.00
IUUC-Sit-109885	Setaria italica	58.03	0.00e+00	642.00
IUUC-Sly-110868	Solanum lycopersicum	65.79	0.00e+00	773.00
IUUC-Stu-112829	Solanum tuberosum	65.45	0.00e+00	769.00
IUUC-Sbi-114169	Sorghum bicolor	57.27	0.00e+00	632.00
IUUC-Tca-121450	Theobroma cacao	65.66	0.00e+00	783.00
IUUC-Tae-123343	Triticum aestivum	54.53	6.00e-173	600.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence