iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107326

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01126590

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017481.1	ENSSHAT00000020776.1	ENSSHAP00000020611.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-54	177.7	439	477
UBD/Beta-Prp	1.20e-64	218.6	310	510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 439  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGTLVHS 477
           9**********999*******************999876 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
            +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++
   Q: 310  LDVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKW 397
           33444.55555666666666666666665566666666666666666666666666666666666666666666666666666666666 PP
   S: 103  sp.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           sp         s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ 
   Q: 398  SPtgpgtsnptSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRG--TGG 483
           5544444443223455666666666666666666666.6666666666666666666666666666666666666666666655..666 PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdl 209
           +  + ++  g  + + + dg+v + dl
   Q: 484  IFEVCWNARGDKVGASASDGSVCVLDL 510
           666666666666666666666655555 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQXXXXA AVTPAAISQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCATAA CCAGCGACGA AGTGAATTTT TTGGTATATC GTTATCTCCA GGAGTCAGGT 60
AAATTATTCA TCTTTCAGTC AGTAAGCAGC ATTTCTGAAG TCAACTGTGT ACAGTATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

KEGG

shr:100927158

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	95.90	0.00e+00	1003.00
IUUC-Apl-003232	Anas platyrhynchos	94.84	0.00e+00	1008.00
IUUC-Aca-005035	Anolis carolinensis	93.55	0.00e+00	1016.00
IUUC-Ago-007869	Ashbya gossypii	25.64	3.00e-40	159.00
IUUC-Bta-013202	Bos taurus	94.32	0.00e+00	1013.00
IUUC-Cja-019281	Callithrix jacchus	92.26	0.00e+00	987.00
IUUC-Cfa-020929	Canis familiaris	94.11	0.00e+00	1009.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.16	6.00e-132	464.00
IUUC-Csa-023943	Chlorocebus sabaeus	91.75	0.00e+00	983.00
IUUC-Cin-025704	Ciona intestinalis	72.68	0.00e+00	802.00
IUUC-Csv-026257	Ciona savignyi	70.97	0.00e+00	768.00
IUUC-Cne-026946	Cryptococcus neoformans	38.46	1.00e-30	128.00
IUUC-Cme-027258	Cyanidioschyzon merolae	40.38	2.00e-107	382.00
IUUC-Dno-028926	Dasypus novemcinctus	92.41	0.00e+00	995.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	3.00e-176	611.00
IUUC-Ete-032822	Echinops telfairi	83.78	0.00e+00	851.00
IUUC-Eca-033897	Equus caballus	94.68	0.00e+00	1013.00
IUUC-Fca-036462	Felis catus	94.12	0.00e+00	1010.00
IUUC-Fal-037388	Ficedula albicollis	95.60	0.00e+00	1019.00
IUUC-Gga-040671	Gallus gallus	95.60	0.00e+00	1019.00
IUUC-Gac-041851	Gasterosteus aculeatus	91.03	0.00e+00	945.00
IUUC-Gma-044208	Glycine max	47.64	5.00e-153	534.00
IUUC-Ggo-045373	Gorilla gorilla	91.27	0.00e+00	991.00
IUUC-Hsa-045841	Homo sapiens	91.44	0.00e+00	991.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	98.92	0.00e+00	774.00
IUUC-Lch-050535	Latimeria chalumnae	94.53	0.00e+00	988.00
IUUC-Laf-054071	Loxodonta africana	93.95	0.00e+00	1013.00
IUUC-Mcc-055233	Macaca mulatta	91.98	0.00e+00	967.00
IUUC-Mtr-058681	Medicago truncatula	59.62	7.00e-132	464.00
IUUC-Mga-059895	Meleagris gallopavo	95.42	0.00e+00	1018.00
IUUC-Mmr-061286	Microcebus murinus	94.53	0.00e+00	1018.00
IUUC-Mmu-063447	Mus musculus	94.12	0.00e+00	1009.00
IUUC-Nle-069151	Nomascus leucogenys	91.41	0.00e+00	987.00
IUUC-Ont-072252	Oreochromis niloticus	91.42	0.00e+00	972.00
IUUC-Oan-073562	Ornithorhynchus anatinus	95.45	0.00e+00	1027.00
IUUC-Oba-075618	Oryza barthii	48.47	1.00e-143	503.00
IUUC-Ogl-077302	Oryza glaberrima	50.63	1.00e-155	542.00
IUUC-Ogu-078718	Oryza glumaepatula	50.63	1.00e-155	543.00
IUUC-Oin-079515	Oryza indica	44.34	3.00e-94	339.00
IUUC-Ome-081696	Oryza meridionalis	49.55	2.00e-150	525.00
IUUC-Oni-082137	Oryza nivara	50.63	1.00e-155	543.00
IUUC-Opu-083505	Oryza punctata	48.11	3.00e-143	501.00
IUUC-Oru-085276	Oryza rufipogon	50.63	6.00e-156	543.00
IUUC-Osa-085791	Oryza sativa	50.63	1.00e-155	543.00
IUUC-Olu-087589	Ostreococcus lucimarinus	53.76	1.00e-157	549.00
IUUC-Oar-089506	Ovis aries	97.27	0.00e+00	1014.00
IUUC-Ptr-090793	Pan troglodytes	91.03	0.00e+00	959.00
IUUC-Pan-091909	Papio anubis	92.19	0.00e+00	991.00
IUUC-Psi-093358	Pelodiscus sinensis	93.36	0.00e+00	970.00
IUUC-Pfo-097214	Poecilia formosa	90.45	0.00e+00	942.00
IUUC-Pab-098317	Pongo abelii	91.28	0.00e+00	971.00
IUUC-Pop-098989	Populus trichocarpa	57.64	6.00e-129	453.00
IUUC-Ppe-101572	Prunus persica	63.69	6.00e-128	450.00
IUUC-Rno-105857	Rattus norvegicus	94.12	0.00e+00	1009.00
IUUC-Sce-106132	Saccharomyces cerevisiae	25.27	1.00e-43	170.00
IUUC-Sly-111042	Solanum lycopersicum	51.27	7.00e-152	530.00
IUUC-Stu-112786	Solanum tuberosum	49.23	3.00e-144	504.00
IUUC-Ssc-115646	Sus scrofa	94.71	0.00e+00	1019.00
IUUC-Tgu-116898	Taeniopygia guttata	95.03	0.00e+00	1010.00
IUUC-Tru-117862	Takifugu rubripes	91.42	0.00e+00	960.00
IUUC-Tni-119656	Tetraodon nigroviridis	92.40	0.00e+00	955.00
IUUC-Ttr-128826	Tursiops truncatus	94.80	0.00e+00	927.00
IUUC-Vvi-131193	Vitis vinifera	56.89	3.00e-129	455.00
IUUC-Xma-133591	Xiphophorus maculatus	90.25	0.00e+00	940.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence