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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-032085
UUCD1 version UUC-DrM-00357
Ensembl Protein ID FBpp0079266
UniProt Accession Q9VLN1; WDR82_DROME
Genbank Protein ID AAF52654.1; AAL39226.1
Protein Name WD repeat-containing protein 82
Genbank Nucleotide ID AE014134; AY069081
Gene Name Wdr82; CG17293
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0032030 FBtr0079650 FBpp0079266
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
CPLMdbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-25 88.6 107 143
UBD/Beta-Prp 2.60e-42 145.0 17 309
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt +v +l+  +  ++++sGs D+t+++WDlr+ ++
   Q: 107  GHTKKVISLCIsPVeDTFLSGSLDKTLRLWDLRSPNC 143
           8**********955689***************99877 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgse..Drtikvwdlstgkcvhtlkghedsvls 99
           +++ ++++ i++++f+p++++l++ s+d+ i ++d ++g+  r++ +++ +v  + f +  ++ + +s+  D+ti+  +l ++k+++ + gh+++v s
   Q: 17   KIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTkvDDTIRYLSLHDNKYLRYFPGHTKKVIS 114
           67788999***************************************************9997776665449************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....ktgkllrtltgghtdsvyslsfdsngk 193
           l +sp  d+++sGs d+t+r+wdl++  c       h +   +++++p+g ++++G + + ++l+dl    k  ++  +l ++++ + + l+f+++gk
   Q: 115  LCISPVEDTFLSGSLDKTLRLWDLRSPNCQG---LMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLrsfdKGPFVTFKLNQEKECDWTGLKFSRDGK 209
           *****************************97...4566666699***********************7665555666666555777777788****** PP
   S: 194  elvsgsldgtvklwdlqtgecvrtlnghtdn...vksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedsk 288
            ++   + + ++l+d  +g+ ++t++g+ +n   +    fsp+++++ sgs Dg + iW+ ++g+ +++l++ +    +v++++f+ ++++l+s+  +
   Q: 210  TILISTNGSVIRLVDAFHGTPLQTFTGYPNNkgiPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGDH--PGPVQCVQFNPKYMMLASACTN 305
           ***************************87661114568888*******************************55..99****************9767 PP
   S: 289  vniw 292
             +w
   Q: 306  MAFW 309
           7666 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3.
 Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3.
Protein Sequence
(Fasta)
MKIKLIDSVV RSFKVAKIFR ENTDKINAID FAPNGEHLIS CSEDDQIVIY DCEKGTQSRT 60
VNSKKYGVDL IHFTHANNTA IHSSTKVDDT IRYLSLHDNK YLRYFPGHTK KVISLCISPV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032085|E3,WD_repeat;UBD,Beta-Prp|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCACCGATA ACATTGTTTG CAACAATTGA GCATATTGAC AACAAAACGA AATTCGACAG 60
GCTAAAATGA AGATAAAACT AATAGATTCG GTGGTGCGCA GTTTTAAGGT GGCCAAGATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032085|E3,WD_repeat;UBD,Beta-Prp|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0048188--C:Set1C/COMPASS complex
GO:0003682--F:chromatin binding
GO:0051568--P:histone H3-K4 methylation
GO:0080182--P:histone H3-K4 trimethylation
GO:0019233--P:sensory perception of pain
KEGG dme:Dmel_CG17293
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000390 Aegilops tauschii 36.86 7.00e-62 229.00
IUUC-Aml-001221 Ailuropoda melanoleuca 69.01 6.00e-137 479.00
IUUC-Atr-002607 Amborella trichopoda 41.67 1.00e-72 265.00
IUUC-Apl-003817 Anas platyrhynchos 69.08 4.00e-132 464.00
IUUC-Aca-005383 Anolis carolinensis 69.01 1.00e-135 474.00
IUUC-Aly-005437 Arabidopsis lyrata 39.24 3.00e-70 258.00
IUUC-Ath-006793 Arabidopsis thaliana 39.24 5.00e-70 256.00
IUUC-Ago-007804 Ashbya gossypii 35.44 1.00e-50 192.00
IUUC-Acl-008217 Aspergillus clavatus 36.23 2.00e-56 211.00
IUUC-Afl-008539 Aspergillus flavus 36.71 8.00e-58 216.00
IUUC-Afu-009105 Aspergillus fumigatus 36.36 4.00e-57 214.00
IUUC-Ani-009474 Aspergillus nidulans 36.61 7.00e-56 210.00
IUUC-Ang-009858 Aspergillus niger 36.55 5.00e-58 217.00
IUUC-Aor-009955 Aspergillus oryzae 36.71 8.00e-58 216.00
IUUC-Ate-010364 Aspergillus terreus 37.54 1.00e-58 219.00
IUUC-Ame-010661 Astyanax mexicanus 68.09 8.00e-131 459.00
IUUC-Bgr-012008 Blumeria graminis 34.75 2.00e-55 208.00
IUUC-Bta-013022 Bos taurus 69.08 3.00e-132 464.00
IUUC-Bci-013966 Botrytis cinerea 38.15 6.00e-53 200.00
IUUC-Bdi-015066 Brachypodium distachyon 41.48 1.00e-72 265.00
IUUC-Bol-016019 Brassica oleracea 39.12 3.00e-70 257.00
IUUC-Bra-017871 Brassica rapa 38.92 4.00e-70 257.00
IUUC-Cel-018276 Caenorhabditis elegans 45.67 1.00e-76 279.00
IUUC-Cja-019309 Callithrix jacchus 69.01 6.00e-137 479.00
IUUC-Cfa-020345 Canis familiaris 69.01 6.00e-137 479.00
IUUC-Cpo-022227 Cavia porcellus 63.17 8.00e-120 422.00
IUUC-Csa-023267 Chlorocebus sabaeus 66.45 7.00e-135 472.00
IUUC-Cho-024409 Choloepus hoffmanni 61.02 8.00e-105 372.00
IUUC-Cin-025628 Ciona intestinalis 73.19 2.00e-146 510.00
IUUC-Csv-026164 Ciona savignyi 72.29 1.00e-144 504.00
IUUC-Cgl-026516 Colletotrichum gloeosporioides 34.94 2.00e-50 192.00
IUUC-Cne-026890 Cryptococcus neoformans 31.17 1.00e-41 162.00
IUUC-Cme-027288 Cyanidioschyzon merolae 37.20 4.00e-63 234.00
IUUC-Dre-028001 Danio rerio 68.69 9.00e-136 475.00
IUUC-Dno-029056 Dasypus novemcinctus 69.01 6.00e-137 479.00
IUUC-Dor-031078 Dipodomys ordii 68.63 1.00e-89 321.00
IUUC-Dse-031152 Dothistroma septosporum 35.84 5.00e-58 217.00
IUUC-Ete-033158 Echinops telfairi 66.45 6.00e-132 462.00
IUUC-Eca-033879 Equus caballus 70.16 4.00e-112 397.00
IUUC-Eeu-035229 Erinaceus europaeus 60.53 9.00e-111 392.00
IUUC-Fca-035896 Felis catus 69.01 6.00e-137 479.00
IUUC-Fal-036843 Ficedula albicollis 69.08 3.00e-132 464.00
IUUC-Fox-037858 Fusarium oxysporum 35.24 1.00e-54 206.00
IUUC-Fso-038386 Fusarium solani 33.72 3.00e-45 174.00
IUUC-Gmo-038506 Gadus morhua 67.87 3.00e-129 454.00
IUUC-Ggr-040090 Gaeumannomyces graminis 35.10 6.00e-53 200.00
IUUC-Gga-040192 Gallus gallus 69.01 2.00e-136 477.00
IUUC-Gac-042494 Gasterosteus aculeatus 66.34 1.00e-126 446.00
IUUC-Gma-044074 Glycine max 40.00 6.00e-71 259.00
IUUC-Ggo-045204 Gorilla gorilla 69.08 8.00e-133 466.00
IUUC-Hsa-045866 Homo sapiens 69.01 6.00e-137 479.00
IUUC-Hvu-047690 Hordeum vulgare 37.18 9.00e-63 233.00
IUUC-Itr-048338 Ictidomys tridecemlineatus 69.01 6.00e-137 479.00
IUUC-Kpa-049249 Komagataella pastoris 37.34 6.00e-54 203.00
IUUC-Lch-050431 Latimeria chalumnae 68.51 7.00e-133 466.00
IUUC-Lpe-050830 Leersia perrieri 40.19 1.00e-70 259.00
IUUC-Loc-052505 Lepisosteus oculatus 62.50 9.00e-27 111.00
IUUC-Lma-053026 Leptosphaeria maculans 35.28 6.00e-56 210.00
IUUC-Laf-054265 Loxodonta africana 55.34 1.00e-94 338.00
IUUC-Mcc-055583 Macaca mulatta 69.01 6.00e-137 479.00
IUUC-Meu-056113 Macropus eugenii 56.87 1.00e-105 375.00
IUUC-Mor-057267 Magnaporthe oryzae 33.92 1.00e-45 176.00
IUUC-Mpo-057502 Magnaporthe poae 34.22 1.00e-50 192.00
IUUC-Mtr-058200 Medicago truncatula 40.31 6.00e-71 260.00
IUUC-Mla-058815 Melampsora laricipopulina 40.00 2.00e-70 258.00
IUUC-Mga-059407 Meleagris gallopavo 70.43 3.00e-116 410.00
IUUC-Mvi-060411 Microbotryum violaceum 38.23 4.00e-66 244.00
IUUC-Mmr-061470 Microcebus murinus 69.01 6.00e-137 479.00
IUUC-Mdo-062860 Monodelphis domestica 68.37 2.00e-135 474.00
IUUC-Mmu-063105 Mus musculus 69.01 6.00e-137 479.00
IUUC-Mac-065314 Musa acuminata 41.19 2.00e-71 261.00
IUUC-Mpu-066472 Mustela putorius furo 70.04 2.00e-116 410.00
IUUC-Mlu-067073 Myotis lucifugus 69.06 1.00e-134 471.00
IUUC-Nfi-068284 Neosartorya fischeri 36.36 3.00e-57 214.00
IUUC-Ncr-068702 Neurospora crassa 35.84 3.00e-46 177.00
IUUC-Nle-069451 Nomascus leucogenys 69.01 6.00e-137 479.00
IUUC-Opr-071112 Ochotona princeps 70.04 2.00e-116 410.00
IUUC-Ont-071988 Oreochromis niloticus 67.43 9.00e-130 456.00
IUUC-Oan-072947 Ornithorhynchus anatinus 70.43 3.00e-116 409.00
IUUC-Ocu-074969 Oryctolagus cuniculus 69.01 6.00e-137 479.00
IUUC-Oba-075229 Oryza barthii 35.46 3.00e-57 215.00
IUUC-Obr-076456 Oryza brachyantha 40.51 4.00e-71 260.00
IUUC-Ogl-076973 Oryza glaberrima 40.51 4.00e-71 260.00
IUUC-Ogu-078068 Oryza glumaepatula 35.67 2.00e-57 215.00
IUUC-Oin-079656 Oryza indica 40.51 4.00e-71 260.00
IUUC-Olo-080893 Oryza longistaminata 33.76 9.00e-51 192.00
IUUC-Ome-081559 Oryza meridionalis 36.46 1.00e-32 132.00
IUUC-Oni-082990 Oryza nivara 35.14 5.00e-57 214.00
IUUC-Opu-083374 Oryza punctata 35.67 1.00e-57 215.00
IUUC-Oru-084354 Oryza rufipogon 35.14 6.00e-57 214.00
IUUC-Osa-086296 Oryza sativa 40.51 4.00e-71 260.00
IUUC-Ola-087095 Oryzias latipes 67.09 9.00e-134 468.00
IUUC-Olu-087603 Ostreococcus lucimarinus 36.70 6.00e-55 206.00
IUUC-Oga-088766 Otolemur garnettii 69.01 6.00e-137 479.00
IUUC-Oar-089565 Ovis aries 67.41 2.00e-132 464.00
IUUC-Ptr-091219 Pan troglodytes 64.54 2.00e-131 460.00
IUUC-Pan-091733 Papio anubis 69.01 6.00e-137 479.00
IUUC-Psi-092972 Pelodiscus sinensis 68.20 2.00e-130 458.00
IUUC-Pma-094332 Petromyzon marinus 70.93 4.00e-144 503.00
IUUC-Pno-094960 Phaeosphaeria nodorum 37.61 2.00e-58 218.00
IUUC-Ppa-095292 Physcomitrella patens 45.83 4.00e-82 296.00
IUUC-Pfo-096775 Poecilia formosa 67.11 2.00e-129 455.00
IUUC-Pab-098340 Pongo abelii 66.13 5.00e-134 469.00
IUUC-Pop-099608 Populus trichocarpa 43.08 5.00e-74 270.00
IUUC-Pca-100635 Procavia capensis 69.65 5.00e-113 399.00
IUUC-Ppe-101452 Prunus persica 41.72 6.00e-72 263.00
IUUC-Pva-102798 Pteropus vampyrus 68.37 8.00e-136 475.00
IUUC-Pgr-103395 Puccinia graminis 39.72 7.00e-75 273.00
IUUC-Ptt-103747 Puccinia triticina 39.71 8.00e-72 263.00
IUUC-Pte-104129 Pyrenophora teres 36.70 1.00e-53 204.00
IUUC-Pyt-104773 Pyrenophora triticirepentis 34.59 3.00e-56 211.00
IUUC-Rno-106127 Rattus norvegicus 67.20 2.00e-130 457.00
IUUC-Sce-106257 Saccharomyces cerevisiae 35.65 1.00e-46 179.00
IUUC-Sha-107529 Sarcophilus harrisii 62.94 2.00e-126 444.00
IUUC-Sja-107724 Schizosaccharomyces japonicus 33.86 5.00e-47 180.00
IUUC-Spo-108206 Schizosaccharomyces pombe 34.65 3.00e-50 191.00
IUUC-Smo-108979 Selaginella moellendorffii 44.19 4.00e-79 286.00
IUUC-Sit-109858 Setaria italica 40.38 1.00e-70 258.00
IUUC-Sly-111267 Solanum lycopersicum 42.99 6.00e-72 263.00
IUUC-Sar-113079 Sorex araneus 70.04 2.00e-116 410.00
IUUC-Sbi-114094 Sorghum bicolor 35.67 7.00e-60 223.00
IUUC-Sre-115157 Sporisorium reilianum 35.41 7.00e-56 210.00
IUUC-Ssc-116386 Sus scrofa 69.01 6.00e-137 479.00
IUUC-Tgu-116465 Taeniopygia guttata 70.28 8.00e-111 393.00
IUUC-Tru-117604 Takifugu rubripes 67.43 6.00e-131 460.00
IUUC-Tsy-119314 Tarsius syrichta 53.63 5.00e-77 279.00
IUUC-Tni-120237 Tetraodon nigroviridis 67.43 1.00e-129 455.00
IUUC-Tca-121853 Theobroma cacao 41.19 7.00e-72 263.00
IUUC-Tre-122205 Trichoderma reesei 34.19 1.00e-52 199.00
IUUC-Tvi-122471 Trichoderma virens 29.83 2.00e-38 152.00
IUUC-Tae-125200 Triticum aestivum 41.80 2.00e-73 268.00
IUUC-Tur-126512 Triticum urartu 39.49 6.00e-59 220.00
IUUC-Tme-126883 Tuber melanosporum 39.14 5.00e-58 217.00
IUUC-Tbe-127310 Tupaia belangeri 59.09 2.00e-47 181.00
IUUC-Ttr-128307 Tursiops truncatus 70.04 2.00e-116 410.00
IUUC-Uma-129579 Ustilago maydis 35.09 7.00e-55 206.00
IUUC-Vda-129826 Verticillium dahliae 34.67 8.00e-50 190.00
IUUC-Vpa-130091 Vicugna pacos 70.04 2.00e-116 410.00
IUUC-Vvi-131587 Vitis vinifera 39.94 5.00e-70 256.00
IUUC-Xtr-132660 Xenopus tropicalis 66.13 4.00e-129 454.00
IUUC-Xma-133496 Xiphophorus maculatus 67.09 5.00e-134 469.00
IUUC-Yli-134509 Yarrowia lipolytica 37.46 1.00e-60 225.00
IUUC-Zma-134685 Zea mays 40.51 1.00e-70 259.00
Created Date 25-Jun-2017

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